Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Techniques such as biochemical assays, Enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting, and immunofluorescence labeling were employed to detect changes in nitric oxide (NO), lactate dehydrogenase (LDH), inflammatory markers, and components of the cartilage matrix in chondrocytes. …”
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Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-κB Pathway by Qingwen Zhang, Jinxia Sun, Yan Fu, Weigang He, Yinhong Li, Hongsheng Tan, Hongxi Xu, Xin Jiang

“…It was evidenced by the decreased production of inflammatory mediators, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2). …”
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NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane therapy via c-JUN repression by Tejaswini Reddy, Akshjot Puri, Liliana Guzman-Rojas, Christoforos Thomas, Wei Qian, Jianying Zhou, Hong Zhao, Bijan Mahboubi, Adrian Oo, Young-Jae Cho, Baek Kim, Jose Thaiparambil, Roberto Rosato, Karina Ortega Martinez, Maria Florencia Chervo, Camila Ayerbe, Noah Giese, David Wink, Stephen Lockett, Stephen Wong, Jeffrey Chang, Savitri Krishnamurthy, Clinton Yam, Stacy Moulder, Helen Piwnica-Worms, Funda Meric-Bernstam, Jenny Chang

“…A clinical study in anthracycline-refractory MpBC patients suggested that nitric oxide synthase (NOS) inhibitor NG-monomethyl-l-arginine (L-NMMA) may augment anti-tumor efficacy of taxane. …”
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Can electronic monitoring with a digital smart spacer support personalised medication adherence and inhaler technique education in patients with asthma?: Protocol of the randomised... by Job F. M. van Boven, Boudewijn H.J. Dierick, Maria Achterbosch, Sandra Been-Buck, Titia Klemmeier, Susanne J. van de Hei, Paul Hagedoorn, Huib A.M. Kerstjens, Janwillem W.H. Kocks

“…At t=-1, t=0 and t=1 month, the Asthma Control Questionnaire (ACQ), Work Productivity and Activity Impairment (WPAI) questionnaire and Test of Adherence to Inhalers (TAI) are administered and fractional exhaled nitric oxide (FeNO) is assessed. At t=0 and t=1, spirometry is performed. …”
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Structural characterization and anti-inflammatory activities of novel polysaccharides obtained from Pleurotus eryngii by Han Wang, Sai Ma, Alfred Mugambi Mariga, Qiuhui Hu, Qian Xu, Anxiang Su, Ning Ma, Gaoxing Ma

“…Biological activity analysis was then carried out and found that all these polysaccharides could significantly suppress the relative mRNA expression of toll-like receptor 4, nitric oxide (NO), tumor necrosis factor-α, interleukin (IL)-1β and IL-6 in lipopolysaccharide (LPS)-induced inflammation of RAW264.7 cells, as well as the over secretion of the above cell cytokines. …”
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Tumor Anti-Initiation and Anti-Progression Properties of Sulphated-Extract of Colocasia esculenta by Amira M. Gamal-Eldeen, Hassan Amer ‎, Cinderella A. ‎ Fahmy, Haytham ‎ Dahlawi, Basem H ‎ Elesawy, Nahla L. ‎ Faizo, Bassem M. ‎ Raafat

“…It induced lymphocyte growth and modulated the macrophage functions into an anti-inflammatory profile, via elevating macrophage proliferation and its binding affinity of fluorescein isothiocyanate-lipopolysaccharide (FITC-LPS) and inhibiting nitric oxide and tumor necrosis factor-α generation. Furthermore, SCE showed a potent cytotoxicity against human breast MCF-7 carcinoma cells (IC 50 27.73 µg/mL), whereas SCE treatment inhibited the activity of histone deacetylase (HDAC IC 50 37.70 µg/mL) and disturbed the pattern of cell cycle phases. …”
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Wedge‐Like Microstructure of Al2O3/i‐Ti3C2Tx Electrode with “Nano‐Pumping” Effect for Boosting Ion Diffusion and Electrochemical Defluoridation by Junce Wang, Jinfeng Chen, Ningning Liu, Jingjing Lei, Hong‐Wen Gao, Fei Yu, Fanghui Pan, Jie Ma

“…The wedge‐like microstructure of aluminum oxide/incomplete‐Ti3C2Tx MXene (Al2O3/i‐Ti3C2 Tx) is constructed by incomplete etching MAX and in situ derivation of A‐layer element, in which the sub‐nanoscale interlayer space is conducive to the small size ions intercalation, and the formation of “nanopump‐like” effect boosted the ions diffusion. …”
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The Role of Tetrahydrobiopterin and Dihydrobiopterin in Ischemia/Reperfusion Injury When Given at Reperfusion by Qian Chen, Elizabeth Eun Jung Kim, Katrina Elio, Christopher Zambrano, Samuel Krass, Jane Chun-wen Teng, Helen Kay, Kerry-Anne Perkins, Sailesh Pershad, Sloane McGraw, Jeffrey Emrich, Jovan S. Adams, Lindon H. Young

“…Reduced nitric oxide (NO) bioavailability and increased oxidative stress are major factors mediating ischemia/reperfusion (I/R) injury. …”
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Impact of heavy metal pollution on the use of fishing pond land, a former site of used battery smelting by E. Riani, N.A. Butet, M. Ansori, M.R. Cordova

“…Other metals are present because lead and lead oxide plates are impure and associated with other minerals. …”
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Microstructure regulation mechanism of CuW composites prepared by aluminothermic coupling with magnesiothermic reduction by Xin-Yu Wang, Chu Cheng, Yan-Shuo Feng, Meng-Xin Wang, Ming-Yu Li, Tao Huang, Ling-Ling Xiong, Kai Li, Zhi-He Dou, Ting-An Zhang, Ke-Xing Song

“…The mechanism was that magnesium was converted into magnesium vapor during the rapid heating process of the system, and the gas-solid, gas-liquid-solid reaction occurred with tungsten oxide to generate smaller tungsten particles. With an increase of magnesium content, the average size of tungsten particles in the microstructure of CuW gradually decreased from 2.38 μm to 0.82 μm, and the microstructure uniformity increased from 56.26% to 76.96%.…”
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Ultrasound stimulated perfluorobutane microbubbles cavitation enhanced the therapeutic effect of colchicine in rats with acute gouty arthritis by Ji-cheng Zhang, Bo Gou, Tian-rui Wang, Wan-tai Dang, Yan-hui Li, Wen Wen, Jian Liu

“…For the evaluation of vascular inflammation and dilation, plasma interleukin-1β (IL-1β) and endothelial nitric oxide synthase (eNOS) served as the key indicators. …”
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Materials and devices for high‐density, high‐throughput micro‐electrocorticography arrays by Yang Xie, Yanxiu Peng, Jinhong Guo, Muyang Liu, Bozhen Zhang, Lan Yin, He Ding, Xing Sheng

“…Furthermore, recent findings highlight the need for further research and development in active transistor arrays, including silicon, metal oxide, and solution-gated transistors. These active transistor arrays have the potential to unlock the capabilities of high-density, high-throughput µECoG devices and overcome the limitations of passive multielectrode arrays. …”
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Long-term effects of dupilumab on chronic rhinosinusitis with nasal polyps: A step towards clinical remission by Mona Al-Ahmad, MD, FRCPC, Asmaa Ali, MD, PhD, Wafaa Talat, MD, PhD, Haitham A. Dawood, MD, PhD, Osama Imam, MD, PhD

“…Higher fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC) levels, along with anosmia/hyposmia, predicted larger polyp size. …”
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Design of precursors and pH factors for enhancing the performance of nickel-based catalysts for anion exchange membrane water electrolysis by Eon-ju Park, Chiho Kim, Jooyoung Lee, Shin-Woo Myeong, Hoseok Lee, Sungjun Heo, Song Jin, Minjeong Park, Oi Lun Li, Sung Mook Choi

“…In addition, to verify universality of the N-NiO study and to assess the water electrolysis performance, we synthesized a binary compound, nickel–cobalt oxide (NCO), by incorporating Co, and evaluated its electrochemical performance in an AEMWE single-cell system. …”
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Using mechanical and thermodynamic methods to evaluate the effects of nanomaterials on thermal cracking mechanisms of asphalt mixtures under the influence of different moisture con... by Amir Hossein Asadi, Gholam Hossein Hamedi, Alireza Azarhoosh

“…Considering the unique properties of multi-walled carbon nanotubes (MWCNTs) and nano-graphene oxide (NGO), including hydrophobicity, high tensile strength, high modulus of elasticity, and effective outcomes in water treatment industries, these two materials were utilized as bitumen additives at 0.3 and 0.6 % by weight of bitumen to improve the low-temperature performance of bitumen and aggregates against adhesive and cohesive failures under various moisture conditions. …”
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Protective Effects of Thalidomide on High-Glucose-Induced Podocyte Injury through In Vitro Modulation of Macrophage M1/M2 Differentiation by Hui Liao, Yuanping Li, Xilan Zhang, Xiaoyun Zhao, Dan Zheng, Dayue Shen, Rongshan Li

“…The present study explored the effects of Tha on mRNA and protein expressions of inducible nitric oxide synthase (iNOS), tumor necrosis factor- (TNF-) α, mannose receptor (CD206), and arginase- (Arg-) 1 in HG-activated macrophages. iNOS and TNF-α are established as markers of classically activated macrophage (M1). …”
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Two-dimensional anion-rich NaCl2 crystal under ambient conditions by Ruobing Yi, Jie Jiang, Yizhou Yang, Yueyu Zhang, Siyan Gao, Yimin Zhao, Jiahao Hu, Xuchang Su, Xinming Xia, Bingquan Peng, Fangfang Dai, Pei Li, Zhao Guan, Haijun Yang, Fangyuan Zhu, Jiefeng Cao, Zhe Wang, Haiping Fang, Lei Zhang, Liang Chen

“…Here, we report a 2D anion-rich NaCl2 crystal with sandwiched structure confined within graphene oxide membranes with positive surface potential. …”
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Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells by Lulli Daniela, Potapovich Alla, Riccardo Maurelli, Dellambra Elena, Pressi Giovanna, Kostyuk Vladimir, Dal Toso Roberto, De Luca Chiara, Pastore Saveria, Korkina Liudmila

“…Inflammatory responses were induced by UVA+UVB, lipopolysaccharide (LPS), oxidized low-density lipoprotein (oxLDL), and a mixture of proinflammatory cytokines. …”
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Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus by Yue Tian, Ke-yan Chen, Li-dan Liu, Yun-xia Dong, Ping Zhao, Shan-bin Guo

“…Interleukin- (IL-) 1β, nuclear factor-κB (NF-κB), and inducible nitric oxide synthase (iNOS) mRNA expression increased after the rats inhaled sevoflurane in the Aβ-treated group (both P<0.01). …”
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3D Crystal Construction by Single‐Crystal 2D Material Supercell Multiplying by Wenhao Li, Jichuang Shen, Yaqing Ma, Xiang Xu, Han Chen, Lida Yu, Chen Ji, Menglin He, Kezhao Ma, Yiwei Duo, Li Wang, Tongbo Wei, Liping Shi, Muhong Wu, Kaihui Liu, Huaze Zhu, Wei Kong

“…Additionally, the approach accommodates the integration of amorphous oxide, enabling the assembly of 3D non‐linear optical crystals with quasi‐phase matching. …”
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