Alterations in gut‐derived uremic toxins before the onset of azotemic chronic kidney disease in cats by Laurens Van Mulders, Ellen Vanden Broecke, Ellen De Paepe, Femke Mortier, Lynn Vanhaecke, Sylvie Daminet

“…Objectives Assess the association between gut‐derived toxins (ie, indoxyl‐sulfate, p‐cresyl‐sulfate, and trimethylamine‐N‐oxide [TMAO]) and the onset of azotemic CKD in cats. …”
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Muscarinic acetylcholine receptor 3 localized to primary endothelial cilia regulates blood pressure and cognition by Hannah C. Saternos, Kathleen V. Forero, Mahmood A. Meqdad, Raghad Buqaileh, Clare L. Sunderman, Gillian Gallagher, William S. Messer, Ashraf M. Mohieldin, Claudio A. Mucci, Sanjana Kumariya, Islam A. Osman, James P. Burkett, Wissam A. AbouAlaiwi

“…Abstract We previously demonstrated that the inability of primary endothelial cilia to sense fluid shear stress can lead to nitric oxide (NO) deficiency and cause hypertension (HTN). …”
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Improvement of engineering properties and environmental impact of fired clay bricks utilizing industry sludge waste by Amir Detho, Aeslina Abdul Kadir, Ahmad Shayuti, Bin Abdul Rahim, Nejib Ghazouani, Abdelkader Mabrouk, Ahmed Babeker Elhag, Hesham Hussein Rassem

“…X-ray Fluorescence Spectrometry (XRF) analysis reveals that both clay soil and mosaic sludge contain high levels of silicon dioxide (SiO₂) and aluminum oxide (Al₂O₃), supporting their suitability as partial substitutes for clay soil. …”
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Changes in Gastric Smooth Muscle Cell Contraction during Pregnancy: Effect of Estrogen by Othman A. Al-Shboul, Hanan J. Al-Rshoud, Ahmed N. Al-Dwairi, Mohammad A. Alqudah, Mahmoud A. Alfaqih, Ayman G. Mustafa, Mohammad Jaafar

“…The aim of the current study was to explore the changes in the expression of estrogen receptors (ERs) and examine the effect of estrogen on nitric oxide- (NO-) cyclic guanosine monophosphate (cGMP) pathway and thus relaxation in gastric smooth muscle cells (GSMC) during pregnancy. …”
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Protective role of 3-mercaptopyruvate sulfurtransferase (MPST) in the development of metabolic syndrome and vascular inflammation by Paraskevas Zampas, Zhen Li, Antonia Katsouda, Aimilia Varela, Stelios Psarras, Constantinos H. Davos, David J. Lefer, Andreas Papapetropoulos

“…Mice were fed a high-fat diet (HFD) for 15 weeks to induce obesity and hyperglycemia and administrated a nitric oxide synthase inhibitor, during the last 5 weeks to induce hypertension and MetS. …”
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Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia by Carolina Muscoli, Concetta Dagostino, Sara Ilari, Filomena Lauro, Micaela Gliozzi, Erlisa Bardhi, Ernesto Palma, Vincenzo Mollace, Daniela Salvemini

“…Overactivation of this receptor releases superoxide and nitric oxide that, in turn, forms peroxynitrite (PN). All of these events have been linked to neurotoxicity. …”
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In Vitro Free Radical Scavenging Properties and Anti-Inflammatory Activity of Ilex paraguariensis (Maté) and the Ability of Its Major Chemical Markers to Inhibit the Production of... by Ingrid Vicente Farias, Eduarda Fratoni, Lais Cristina Theindl, Angela Machado de Campos, Eduardo Monguilhott Dalmarco, Flavio Henrique Reginatto

“…The chemical profile was achieved by Folin-Ciocalteu, by LC/DAD, and by LC/MS assays, while the antioxidant and anti-inflammatory properties were investigated, respectively, by DPPH assay and by inhibition of nitric oxide (Griess reaction) and TNF-α (ELISA). Our results demonstrated that the IA (aqueous infusion extract) showed higher amounts of total phenolic contents (266.62±10.85 mg CAE·g-1 DE), the highest amounts of all six chemical markers (theobromine, 5-O-caffeoylquinic acid, 4-O-caffeoylquinic acid, 3-O-caffeoylquinic acid, caffeine, and rutin), and stronger antioxidant activity (EC50=54.4±5.14 μg·mL−1). …”
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A novel approach for brazing MgF2 ceramic to TA15 alloy using AgCu/GH4169/Bi2O3B2O3ZnO composite braze fillers by Liangbo Sun, Yue Wen, Tao Liu, Chunfeng Liu, Tipeng Shan, Xinghong Zhang, Jie Zhang

“…As a result, a reliable joint system consisting of TA15/TiCu/TiCu2Al/Ag(s,s) + Cu(s,s)/TiCu2Al/TiCuNi + Ag-rich layer/GH4169/nano-oxide layer/glass/Mg3(BO3)F3+MgO + MgF2 reaction layer/MgF2 was formed. …”
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Interaction between Nuclear Receptor and Alpha-Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Ibrahim Albokhadaim, Ali Attiq, Mahmoud Kandeel, Aimi Syamima Abdul Manap, Sameer M. Alhojaily

“…As compared to the WKY control, the SHR control group’s noninvasive blood pressure and basal mean arterial pressure were significantly greater, along with increased arterial stiffness, lower plasma nitric oxide, adiponectin concentration, and antioxidant enzyme levels (all P<0.05). …”
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Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction by Xiaolong Qu, Pan Yang, Li Jiao, Yuehui Yin

“…Griess reaction method, immunofluorescence, and western blotting (WB) were employed to detect the expressions of nitric oxide (NO), platelet endothelial cell adhesion molecule-1 (CD31) and vascular endothelial (VE)-cadherin, zonula occludens protein 1 (ZO-1), occludin, vascular endothelial growth factor (VEGF) and adenosine monophosphate (AMP)-activated protein kinase (AMPK) signaling-related proteins in endothelial cells and mouse cardiomyocytes. …”
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UV-C and Nanomaterial-Based Approaches for Sulfite-Free Wine Preservation: Effects on Polyphenol Profile and Microbiological Quality by Kamila Pachnowska, Jolanta Kochel-Karakulska, Adrian Augustyniak, Valentina Obradović, Ireneusz Ochmian, Sabina Lachowicz-Wiśniewska, Ireneusz Kapusta, Klaudia Maślana, Ewa Mijowska, Krzysztof Cendrowski

“…Therefore, this study aimed to test and implement iron oxide–silica core–shell nanomaterial functionalized with TiO₂ in UV-C treatment of white and red wines. …”
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Rubber intercropping with arboreal and herbaceous species alleviated the global warming potential through the reduction of soil greenhouse gas emissions by Tahir Ashar, Yingying Zhang, Chuan Yang, Wenxian Xu, Muhammad Zeeshan Ul Haq, Hassam Tahir, Hafiz Muhammad Mazhar Abbas, Zhixiang Wu

“…In 0–20 cm soil depth, all rubber plantations acted as net carbon dioxide (CO₂) and nitrous oxide (N₂O) resources, and net methane (CH₄) sinks. …”
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Study on hot deformation behavior and microstructure evolution of ultrafine W-0.5 wt%La2O3 alloy wire during processing by Yuan Yao, Jianwei Guo, Shizhong Wei, Jinghong Yang, Zhou Li, Hongan Geng, Liujie Xu

“…The recrystallization ratio reaches the maximum at 1600 °C/0.01s−1, but it is still not completely recrystallized. Lanthanum oxide gradually aggregates to the grain boundary during the hot deformation process, which improves the thermal deformation activation energy of tungsten. …”
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Traditional Knowledge and Efficacy Analysis of an Emerging Medicinal Food Plant: <i>Disporopsis aspersa</i> by Qingyu Chen, Miaomiao Wang, Xian Hu, Jihai Zhang, Qing Zhang, Congli Xu, Chunlin Long

“…The IC₅₀ for nitric oxide (NO) scavenging activity was 72.7 ± 7.43 μg/mL, showing dose dependence. …”
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Secondary prevention of preeclampsia by Muhammad Ilham Aldika Akbar, Muhammad Ilham Aldika Akbar, Roudhona Rosaudyn, Khanisyah Erza Gumilar, Khanisyah Erza Gumilar, Renuka Shanmugalingam, Gustaaf Dekker, Gustaaf Dekker

“…Metformin, primarily used for improving insulin sensitivity, has potential advantages in decreasing PE incidence due to its anti-inflammatory and vascular properties, particularly in morbidly obese women. Nitric oxide (NO) donors and L-arginine have been shown to effectively reduce vascular resistance and improving blood flow to placenta, potentially reducing PE risk. …”
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Reinforcement of PMMA Denture Base Material with a Mixture of ZrO2 Nanoparticles and Glass Fibers by Mohammed M. Gad, Ahmad M. Al-Thobity, Ahmed Rahoma, Reem Abualsaud, Fahad A. Al-Harbi, Sultan Akhtar

“…This study is aimed at evaluating the hybrid reinforcement effects of zirconium oxide nanoparticles (nano-ZrO2) and glass fibers (GFs) at different ratios on the flexural and impact strengths of a polymethylmethacrylate (PMMA) denture base. …”
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Anesthetic Isoflurane Posttreatment Attenuates Experimental Lung Injury by Inhibiting Inflammation and Apoptosis by Jun-tang Li, Hui Wang, Wei Li, Li-feng Wang, Li-chao Hou, Jing-lan Mu, Xin Liu, Hui-juan Chen, Ke-lang Xie, Nan-lin Li, Chun-fang Gao

“…ISO also inhibited ZY-induced expression and activation of nuclear factor-kappaB p65 and inducible nitric oxide synthase in pulmonary tissue. ZY administration also resulted in the upregulation of heme oxygenase-1 expression and activity in the lung, which was further enhanced by ISO treatment. …”
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Glucagon-Like Peptide-1 Receptor Agonist Liraglutide Ameliorates the Development of Periodontitis by Noritaka Sawada, Kei Adachi, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Shuichiro Kobayashi, Shin-ichi Miyajima, Yuki Suzuki, Takeshi Kikuchi, Makoto Mizutani, Taku Toriumi, Masaki Honda, Akio Mitani, Tatsuaki Matsubara, Keiko Naruse

“…Periodontitis increased inflammatory cell infiltration, macrophage accumulation, and gene expressions of tumor necrosis factor-α and inducible nitric oxide synthase in the gingiva, all of which were ameliorated by liraglutide. …”
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The SPICE Modeling of a Radiation Sensor Based on a MOSFET with a Dielectric HfO₂/SiO₂ Double-Layer by Miloš Marjanović, Stefan D. Ilić, Sandra Veljković, Nikola Mitrović, Umutcan Gurer, Ozan Yilmaz, Aysegul Kahraman, Aliekber Aktag, Huseyin Karacali, Erhan Budak, Danijel Danković, Goran Ristić, Ercan Yilmaz

“…RADFETs, traditionally fabricated as PMOS transistors with SiO₂, are enhanced by incorporating high-k dielectric materials such as HfO₂ to reduce oxide thickness in modern radiation sensors. The fabrication steps of the sensor are outlined, and model parameters, including the threshold voltage and transconductance, are extracted based on experimental data. …”
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Green nanoparticles synthesized from damask rose petals: Evaluation of their antioxidant, antimicrobial, anti-diabetic, anti-Alzheimer, and photocatalytic properties by Zeinab Alizadeh, Mohammad Fattahi, Alireza Farokhzad, Behvar Asghari, Soheil Yousefzadeh-Valendeh, Hadi Alipour, Javier Palazon

“…Green synthesis, an approach that has gained widespread recognition in recent years due to environmental and health concerns, was employed to synthesize green zinc oxide nanoparticles (G-ZnO NPs) using a hydro-alcoholic extract derived from dried damask rose petals. …”
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