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  1. 2541

    CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension by Lea Strohm, Henning Ubbens, Dominika Mihalikova, Alexander Czarnowski, Paul Stamm, Michael Molitor, Stefanie Finger, Matthias Oelze, Dorothee Atzler, Philip Wenzel, Philipp Lurz, Thomas Münzel, Christian Weber, Esther Lutgens, Andreas Daiber, Steffen Daub

    Published 2025-03-01
    “…The hypertensive cell type-specific CD40(L) knockout animals showed only a minor effect on endothelial function, blood pressure, and oxidative stress. Therefore, we conclude that targeting CD40 directly on adipocytes, B-cells, T-cells, or CD40L on platelets is not a promising target to prevent hypertension complications.In summary, TRAF6 inhibition but not adipocyte, B-cell, or T-cell-specific CD40 or platelet-specific CD40L deficiency reduces pathophysiological vascular inflammation in hypertensive mice, suggesting TRAF6 inhibition as a potential therapeutic target in hypertensive patients.…”
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  2. 2542

    The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis by Peiye Zhu, Yunrui Jin, Jiya Sun, Xia Zhou

    Published 2025-01-01
    “…BackgroundThe effects of resveratrol supplementation on inflammation and oxidative stress in patients with type 2 diabetes mellitus (T2DM) were controversial. …”
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  3. 2543

    Anti-oxidation enhancement, inflammation alleviation, and microbial composition optimization of using tussah (Antheraea pernyi) silk fibroin peptides for hyperglycaemia remission. by Rui Mi, Xuejun Li, Yajie Li, Xingfan Du

    Published 2025-01-01
    “…In addition, the TSFP could ameliorate the lipid dysbolism and contribute to a higher anti-oxidation capacity. Moreover, TSFP could alleviate pathological damages and hinder inflammatory processes of diabetic mice. …”
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  4. 2544

    Correlation of Oxidative Stress with Serum Trace Element Levels and Antioxidant Enzyme Status in Beta Thalassemia Major Patients: A Review of the Literature by Q. Shazia, Z. H. Mohammad, Taibur Rahman, Hossain Uddin Shekhar

    Published 2012-01-01
    “…The aim of this review is to scrutinize the relationship between oxidative stress and serum trace elements, degree of damage caused by oxidative stress, and the role of antioxidant enzymes in beta thalassemia major patients. …”
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  5. 2545

    Assessment of Oxidative Stress by the Estimation of Lipid Peroxidation Marker Malondialdehyde (MDA) in Patients with Chronic Periodontitis: A Systematic Review and Meta-Analysis by Khadijah Mohideen, Krithika Chandrasekar, Saranya Ramsridhar, Chandini Rajkumar, Snehashish Ghosh, Safal Dhungel

    Published 2023-01-01
    “…The present systematic review and meta-analysis aimed to assess the oxidative stress-mediated lipid peroxidation end product malondialdehyde (MDA) in periodontitis using the available literature. …”
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  9. 2549

    Characterisation of environmentally persistent free radicals and their contributions to oxidative potential and reactive oxygen species in sea spray and size-resolved ambient particles by Xinji Zhang, Fanyi Wei, Haiyan Fu, Huibin Guo

    Published 2025-01-01
    “…In this regard, the role of recent pollutant environmentally persistent free radicals (EPFRs) should not be overlooked. However, the oxidative toxicity and mass transfer processes of EPFRs in liquid-phase environments remain completely understood. …”
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  10. 2550

    Protein Oxidation in Breast Microenvironment: Nipple Aspirate Fluid Collected from Breast Cancer Women Contains Increased Protein Carbonyl Concentration by Ferdinando Mannello, Gaetana A. Tonti, Virginia Medda

    Published 2009-01-01
    “…Background: Protein carbonyl levels are the most frequently used biomarker of protein oxidation in several human diseases, including cancer. …”
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  11. 2551
  12. 2552

    Enhancing the photocatalytic performance and chemical durability of AZ31 magnesium alloy by incorporating two types of nanoparticles through plasma electrolytic oxidation by Mosab Kaseem, Abdullah H. Alluhayb, Talitha Tara Thanaa, Arash Fattah-alhosseini, Mohammad Alkaseem

    Published 2024-11-01
    “…The technique utilizes a plasma electrolytic oxidation (PEO) method. In this method, both the AZ31 Mg alloy substrate and SnO2/WO3 precursors undergo simultaneous oxidation. …”
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  13. 2553

    Exercise-Intervened Circulating Extracellular Vesicles Alleviate Oxidative Stress in Cerebral Microvascular Endothelial Cells Under Hypertensive Plus Hypoxic Conditions by Smara Sigdel, Shuzhen Chen, Gideon Udoh, Jinju Wang

    Published 2025-01-01
    “…Cellular migration ability and oxidative stress were evaluated. We found that treadmill exercise stimulated cEV release, and ET-cEVs were more prone to be internalized by mBMECs. …”
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  18. 2558

    Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors by Yifan Yang, Jing Xu, Qingxin Su, Yiran Wu, Qizheng Li, Zongren Ma, Tao Ding

    Published 2022-01-01
    “…The Rho kinase inhibitor (Y-27632) can attenuate LPA-induced apoptosis, DNA damage, and oxidative stress in spinal cord neurons. Moreover mechanistic investigation indicated that LPA (18 : 1) activates Gα12/13–Rho–ROCK2-induced apoptosis, DNA damage, and oxidative stress in spinal cord neurons by upregulating LPA4/LPA6 receptors. …”
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  19. 2559

    Tilia species (linden) exert anti-cancer effects on MIA PaCa-2 cells through the modulation of oxidative stress and inflammation by Gamze Yüksel, Yağmur Özhan, Dilara Güreşçi, Etil Güzelmeriç, Nisa Beril Şen, İpek Bedir, Onur Senol, Gizem Emre, Dilek Telci, Vilma Petrikaitė, Hande Sipahi

    Published 2025-01-01
    “…Abstract This study investigated the anti-cancer effects of the chemically characterized Tilia species (linden) on MIA PaCa-2 cells by analyzing various cancer-triggering mechanisms, including oxidative stress and inflammation status. Extracts from the flowers, bracts, and inflorescences of T. cordata, T. platyphyllos, T. rubra, and T. tomentosa were evaluated for antioxidant activity; subsequently, their ability to mitigate inflammation was assessed through in vitro nitrite assays in LPS-induced RAW264.7 cells. …”
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