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Prevention of osteoporosis in ovariectomized mice with calcium yak caseinate
Published 2025-05-01“…ABSTRACT: Moderate calcium supplementation coupled with enhanced calcium absorption rates in postmenopausal women is crucial for the prevention of postmenopausal osteoporosis (PMOP). …”
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Effects of Vitamin E on Bone Biomechanical and Histomorphometric Parameters in Ovariectomized Rats
Published 2013-01-01“…The present study examined the dose-dependent effect of vitamin E in reversing bone loss in ovariectomized (Ovx) rats. Sprague-Dawley rats were either Sham-operated (Sham) or Ovx and fed control diet for 120 days to lose bone. …”
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Dietary sesame diminishes bone mass and bone formation indices in ovariectomized rats
Published 2020-08-01“…Results: The femur BMD in the Ovx + SSI group was lower than in the Ovx group, as were the measurements for bone formation rate and mineralizing surface. Conclusion: Administration of a methanol extract of sesame seeds decreased femur BMD in Ovx rats.…”
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Therapeutic effect of Cnidium officinale Makino extract on ovariectomized hind-limb ischemic mice
Published 2019-06-01“…Methods: In this study, female C57BL/6 mice were ovariectomized, and the vessels of the hind-limb were excised after ligation by surgical silk (6–0). …”
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Daidzein improves neuronal health and alleviates inflammation and apoptosis through BDNF and estrogen receptors in the hippocampus of ovariectomized rats
Published 2025-07-01“…We studied the impact of DDZ on stereological changes, estrogen receptor (ERs) expression, BDNF, GSK-3β, and inflammatory and apoptosis-related genes in the hippocampus of ovariectomized rats, compared to 17β-estradiol (E2).Materials and Methods: OVX rats were treated with DDZ or E2. …”
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Chronic 17β-estradiol treatment improves negative valence, anhedonic profile, and social interactions in ovariectomized, middle-aged female rats
Published 2025-07-01“…Women experience depression at nearly 2-fold higher rates than men, with middle-age during the menopausal transition being particularly vulnerable. …”
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Type 2 Diabetes Mellitus Increases the Risk to Hip Fracture in Postmenopausal Osteoporosis by Deteriorating the Trabecular Bone Microarchitecture and Bone Mass
Published 2019-01-01“…T2DM is linked to an increase in the fracture rate as compared to the nondiabetic population even with normal or raised bone mineral density (BMD). …”
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Sex differences in respiration and redox homeostasis of heart mitochondria in rats on high-fructose diet
Published 2024-08-01“…The experiment was performed on 30 rats divided into five groups: control males, control females, HFD-fed males, HFD- fed females with intact ovaries, ovariectomized HFD-fed females. Heart mitochondria were isolated and indicators of redox homeostasis as well as mitochondrial oxygen consumption rate were determined. …”
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Prolactin induces apoptosis of lactotropes in female rodents.
Published 2014-01-01“…According to our hypothesis, no increase in lactotrope apoptotic rate was observed at proestrus, which likely contributes to pituitary tumorigenesis observed in these animals. …”
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Hearing Vocalizations during First Social Experience with Pups Increase Bdnf Transcription in Mouse Auditory Cortex
Published 2023-01-01“…E2 influenced the rate of maternal behavior but did not significantly affect Bdnf mRNA transcription in the AC. …”
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EXPERIMENTAL SIMULATION OF POST-OPERATIVE COGNITIVE DISORDERS IN RATS
Published 2018-01-01“…Then for three weeks the following behavioral tests were performed in compliance with the protocol: motor activity (Actometer) and exploratory activity in new environment (Open field), social behavior (pair interaction test), novel object recognition, extrapolational deliverance rate, forced swimming, sexual behavior. Ovariectomized female (n = 16) were used as standard opponents for social behavior tests, and hormone-stimulated female rats (n = 26) were used for sexual behavior tests. …”
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Sex differences in metabolic regulation by Gi/o-coupled receptor modulation of exocytosis
Published 2025-03-01“…Additionally, we ovariectomized female mice to investigate the role of sex hormones in our phenotypes. …”
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When estrogen deficiency meets immune responses induced by rabies vaccination
Published 2025-05-01“…Although 100% protection was found, the reduction rate of viral neutralizing antibody titers in the LBNSE-OVX mice was greater than that in the LBNSE-Sham mice. …”
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AVPV Kiss1 neuron-specific knockdown of purinergic P2X2 receptor suppresses LH surge and ovulation in Kiss1-Cre rats
Published 2024-10-01“…Ovulation disorders are a major cause of low pregnancy rates and infertility in humans and livestock. Kisspeptin neurons located in the anteroventral periventricular nucleus (AVPV) are responsible for the generation of the gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) surge and the consequent ovulation in female rodents. …”
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Extract of <i>Curculigo capitulata</i> Ameliorates Postmenopausal Osteoporosis by Promoting Osteoblast Proliferation and Differentiation
Published 2024-12-01“…MCF-7 and HEK-293 cells were utilized to evaluate the estrogen-like activity of Eocc. Apoptosis rates were detected by flow cytometry. In vivo, a bilateral ovariectomized mouse model of PMOP was used to further validate the in vitro findings through histopathological analysis and WB results. …”
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