ApWD40a, a Member of the WD40-Repeat Protein Family, Is Crucial for Fungal Development, Toxin Synthesis, and Pathogenicity in the Ginseng Alternaria Leaf Blight Fungus <i>Alternari... by Jinling Lan, Shengjie Mei, Yingxue Du, Meili Chi, Jiayi Yang, Shuliu Guo, Mingliang Chu, Ronglin He, Jie Gao

“…WD40 repeat-containing proteins are evolutionarily conserved proteins with diverse functions between different organisms. In this study, we characterized the roles of a WD40 repeat-containing protein in <i>A. panax</i>. …”
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Beyond first-line therapy: efficacy and safety outcomes of continuing immunotherapy in extensive stage small cell lung cancer after PD-L1 inhibitor progression by Jianfeng Peng, Xueying Zhai, Xiaomei Liu, Zhaoqin Huang, Yimeng Wang, Peizhu Wu, Ran Gao, Xiangjiao Meng

“…Subgroup analyses revealed a significant survival advantage with IBP treatment in patients presenting with baseline liver metastases, less than three metastatic organs, and those who were nonsmokers. Conclusions: In patients with ES-SCLC who received first-line PD-L1 inhibitors, continuing IBP extended second-line survival without increasing adverse events (AEs). …”
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Systematic Review of Surgical Care in the Incarcerated Population: Identifying Knowledge Gaps for Future Research by Totadri Dhimal, MD, Paula Cupertino, PhD, Aqsa Ghaffar, BS, Yue Li, PhD, Xueya Cai, PhD, Cristopher Soto, BS, Megha Ramaswamy, PhD, MPH, Bruce W. Herdman, PhD, Fergal J. Fleming, MD, MPH, Anthony Loria, MD, MSCI

“…Original research on surgical care for incarcerated individuals was included, excluding case reports/series (<10 patients), abstracts, and studies involving prisoners of war, plastic surgeries for recidivism reduction, transplants using organs from incarcerated individuals, and nonconsensual surgical sterilization. …”
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Understanding and measuring workplace violence in healthcare: a Canadian systematic framework to address a global healthcare phenomenon by Christian Schulz-Quach, Brendan Lyver, Charlene Reynolds, Trevor Hanagan, Jennifer Haines, John Shannon, Laura Danielle Pozzobon, Yasemin Sarraf, Sam Sabbah, Sahand Ensafi, Natasha Bloomberg, Jaswanth Gorla, Brendan Singh, Lucas B. Chartier, Marnie Escaf, Diana Elder, Marc Toppings, Brian Hodges, Rickinder Sethi

“…Conclusions Our QI team successfully developed a comprehensive QI project tailored to our organization’s needs. To support healthcare institutions in addressing WPV, we created a 12-step framework designed to assist in developing a systemic QI approach tailored to their unique requirements. …”
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Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus by A. L. Matveev, Ya. A. Khlusevich, I. K. Baykov, I. V.  Babkin, E. P. Goncharova, V. V. Morozova, N. V. Tikunova

“…Notably, DNA of the plasmid pCDNA5/FRT­DHFR­CH­CL was organized in such a way that the restriction sites for rapid cloning of DNA fragments encoding the variable domains of heavy and light chains were inserted upstream of the sequences encoding constant domains of the heavy and light chains of the antibody. …”
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Influence of Irradiance, Flow Rate, Reactor Geometry, and Photopromoter Concentration in Mineralization Kinetics of Methane in Air and in Aqueous Solutions by Photocatalytic Membra... by Ignazio Renato Bellobono, Mauro Rossi, Andrea Testino, Franca Morazzoni, Riccardo Bianchi, Giulia de Martini, Paola Maria Tozzi, Rodica Stanescu, Cristina Costache, Liliana Bobirica, Mauro Luigi Bonardi, Flavia Groppi

“…Kinetics of both substrate disappearance, to yield intermediates, and total organic carbon (TOC) disappearance, to yield carbon dioxide, were followed. …”
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Analysis of Soil Microbial Community Structure and Function in <i>Morchella esculenta</i> Habitats in Jilin Province by Qi Yan, Peng Wang, Zhushan Liu, Ya Yu, Xiao Tan, Xiao Huang, Jiawei Wen, Weidong Zhang

“…A correlation analysis of environmental factors revealed that the genera <i>Luteibacter</i>, <i>Streptomyces</i>, <i>Micromonospora</i>, <i>Nocardia</i>, <i>Actinomadura</i>, and <i>Paenibacillus</i> were positively correlated with soil total nitrogen, total phosphorus, and organic matter content. In contrast, <i>Candidatus Nitrosocosmicus</i> showed a significant positive correlation with rapidly available nutrients. …”
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Flavonoids and anthocyanins in seagrasses: implications for climate change adaptation and resilience by Jana Botes, Jana Botes, Xiao Ma, Xiao Ma, Jiyang Chang, Jiyang Chang, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Dave Kenneth Berger, Dave Kenneth Berger

“…This review highlights the importance of flavonoids in angiosperm stress response and adaptation, examines research on flavonoids in seagrasses, and hypothesizes on the importance of flavonoids in these organisms under climate change.…”
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Soluble ST2 protein as a new biomarker in patientswith precapillary pulmonary hypertension by Marta Banaszkiewicz, Arkadiusz Pietrasik, Szymon Darocha, Michał Piłka, Michał Florczyk, Anna Dobosiewicz, Piotr Kędzierski, Ewa Pędzich-Placha, Janusz Kochman, Grzegorz Opolski, Adam Torbicki, Marcin Kurzyna

“…All patients were evaluated for World Health Organization (WHO) functional class (FC), N-terminal prohormone B-type natriuretic peptide (NT-proBNP), troponin T (TnT), and hemodynamics. …”
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The fate of recessive deleterious or overdominant mutations near mating-type loci under partial selfing by Tezenas, Emilie, Giraud, Tatiana, Véber, Amandine, Billiard, Sylvain

“…Large regions of suppressed recombination having extended over time occur in many organisms around genes involved in mating compatibility (sex-determining or mating-type genes). …”
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Connotation, research status, and development directions of clean coal geology in China by Yuegang TANG, Shaoqing WANG, Xiaoshuai WANG, Xin GUO, Yafeng WANG, Liping XUE, Harold H. Schobert

“…[Issues and Prospects] This study proposes some scientific and technical problems concerning coal formation, organic/inorganic elements, minerals, and clean assessment, positing that future advancements in chemistry, physics, biology, and big data/artificial intelligence (AI) will bring opportunities for the further development of clean coal geology and its applications in large-scale engineering. …”
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Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes by Shuai Zhang, Ruixue Wang, Kun Luo, Shipeng Gu, Xinyu Liu, Junhan Wang, Ludan Zhang, Lin Sun

“…N6-methyladenosine (m6A) in eukaryotic RNA is an epigenetic modification that is critical for RNA metabolism, gene expression regulation, and the development of organisms. Aberrant expression of m6A components appears in a variety of human diseases. …”
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Transcriptomic analysis of Rhipicephalus microplus hemocytes from female ticks infected with Babesia bovis or Babesia bigemina by Rubikah Vimonish, Janaina Capelli-Peixoto, Wendell Johnson, Lowell Kappmeyer, Perot Saelao, Naomi Taus, Chungwon Chung, Massaro Ueti

“…However, Babesia parasites escape and disseminate to other organs through the hemolymph to continue their transmission life cycle. …”
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Urinary Microbiota of Healthy Prepubescent Girls and Boys—A Pilot Study by Yulia L. Naboka, Mikhail I. Kogan, Johannes M. Mayr, Irina A. Gudima, Elizaveta M. Koliva, Violetta M. Kotieva, Marina L. Chernytskaya, Vladimir V. Sizonov

“…Methods: We included healthy children aged between 4 and 10 years who were free of functional or organic urinary tract diseases and had no history of urinary tract infection. …”
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How does gut microbiota affect the vaginitis axis? The mediating role of plasma metabolites by Mo Li, Qianyu Zhang, Tong Wu, Lanfang Ma, Dianxing Hu, Zixuan Yuan, Shixuan Wang, Aiyue Luo, Jinjin Zhang

“…Besides, the human gut and vagina are important organs that are both colonized by thousands of microorganisms impacting human physiology and health. …”
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On the measurement of microclimate by Ilya M. D. Maclean, James P. Duffy, Stef Haesen, Sanne Govaert, Pieter De Frenne, Thomas Vanneste, Jonathan Lenoir, Jonas J. Lembrechts, Marcus W. Rhodes, Koenraad Van Meerbeek

“…Abstract Many organisms live in environments in which temperatures differ substantially from those measured by standard weather stations. …”
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SDUST2023BCO: a global seafloor model determined from a multi-layer perceptron neural network using multi-source differential marine geodetic data by S. Zhou, S. Zhou, J. Guo, H. Zhang, Y. Jia, H. Sun, X. Liu, D. An

“…First, input and output data are organized from the multi-source marine geodetic data to train the MLP model. …”
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Risk assessment and hierarchical classification of foodborne disease epidemics during major events in Beijing: an empirical study based on surveillance data analysis by Jinru JIANG, Yangbo WU, Tongyu WANG, Chao WANG, Yanlin NIU, Di WANG, Liping LI, Qian CHEN, Yao ZHAO, Xiaochen MA

“…MethodsAccording to the World Health Organization's list of foodborne diseases, combined with the foodborne diseases monitored by the Beijing Foodborne Disease Surveillance System during the major sports event from 2016 to 2020 (November to April of the following year) as risk factors, the risk levels of foodborne diseases in the key population and the general population of a major sports event in Beijing were evaluated using the risk matrix method and the Borda count method. …”
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Effects of Different Microplastics on Methane Production and Microbial Community Structure in Anaerobic Digestion of Cattle Manure by Mengjiao Zhang, Congxu Zhao, Tian Yuan, Qing Wang, Qiuxian Zhang, Shuangdui Yan, Xiaohong Guo, Yanzhuan Cao, Hongyan Cheng

“…Physicochemical analyses showed that MPs promoted organic matter hydrolysis on day 4 of AD, leading to the accumulation of volatile fatty acids (VFAs) in the initial stage. …”
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Comparison of Serum Potassium, MagnEsium, and Calcium Levels between Kanamycin and Capreomycin-BASEd Regimen-Treated MultiDrug-Resistant TuBerculosis Patients in Bandung (CEASE MDR... by Arto Yuwono Soeroto, Guntur Darmawan, Rudi Supriyadi, Panji Gugah Bhaskara, Prayudi Santoso, Bachti Alisjahbana, Ida Parwati

“…Moreover, our study supported the 2018 World Health Organization treatment guideline recommendations for removal of kanamycin and capreomycin from the MDR-TB regimens.…”
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