Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract by Mohammad Jad Moussa, Georges C. Tabet, Arlene O. Siefker‐Radtke, Lianchun Xiao, Nathaniel R. Wilson, Jianjun Gao, Christopher J. Logothetis, Petros Grivas, Byron Lee, Amishi Y. Shah, Pavlos Msaouel, Roger Li, Leticia Campos Clemente, Jianping Zhao, Nizar M. Tannir, Ashish M. Kamat, Donna E. Hansel, Charles C. Guo, Matthew T. Campbell, Omar Alhalabi

“…Ninety two (41%) patients had relapse with 77 (83.7%) having distant organs as first metastatic sites, including 10 (10.9%) with exclusive central nervous system (CNS) metastases, mostly (9/10) within 1 year of surgery. …”
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Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis by Ting Zhang, Zhimao Li, Qimin Mei, Joseph Harold Walline, Zhaocai Zhang, Yecheng Liu, Huadong Zhu, Bin Du

“…Systematic search conducted without language restrictions from December 1, 2019 to June 31, 2022 on PubMed, EMBASE, Web of Science, Cochrane library, ProQuest Coronavirus Research Database, COVID-19 Living Overview of the Evidence (L-OVE) subset of Episteminokos and the World Health Organization (WHO) Covid-19 databases. Study was reported according to MOOSE-lists and the PRISMA guidelines. …”
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Effects of nitrogen fertilizer basal-to-top-dressing ratios on maize straw decomposition, soil carbon and nitrogen, and bacterial community structure in different soil textures on... by Jingyu Li, Jingyu Li, Xiaonan Yang, Rui Hou, Yujie Ma, Yanqun Wang, Yang Ma, Wenchao Zhen, Yuanyuan Huang, Xin Fu, Zhengping Peng, Zhengping Peng, Mingxin Men

“…., no N fertilizer (N0) and N fertilizer basal-to-top-dressing ratios of 3:7 (N3:7), 4:6 (N4:6), 5:5 (N5:5), and 6:4 (N6:4)) to investigate the dynamics of maize straw decomposition, changes in soil organic carbon (SOC) and total nitrogen (TN) concentrations, soil bacterial diversity and abundance, and their interactions. …”
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Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy by Wenjun Li, Wenjun Li, Junjiang Sun, Susi Feng, Ariana La Rosa, Panli Zhang, Eveline Y. Wu, Richard Loeser, Chengwen Li, Chengwen Li, Chengwen Li

“…IntroductionRheumatoid arthritis (RA) primarily affects the joints but can also affect multiple organs and profoundly impacts patients’ ability to carry out daily activities, mental health, and life expectancy. …”
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Annual Changes in the Ecological Environment and Microbial Community Structure and Their Correlation Analyses in the Core Area of Dalian National Sea Cucumber Stock Field of China by Xiaotong ZHU, Xiaojun RONG, Bin LI, Yingeng WANG, Jianlong GE, Meijie LIAO, Jinjin WANG, Yanqiang WU, Xintao ZHAO, Guojun SHI

“…The correlation analysis between environmental factors and microbial community structure showed that temperature, pH, and salinity were the major environmental factors affecting the microbial community structure in the water body, whereas organic carbon, sulfide, heavy metal copper, and lead were the chief environmental factors affecting the microbial community structure in the sediments. …”
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Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation by Jiawei Huang, Qingwen Deng, Lai Ling Tsang, Guozhu Chang, Jinghui Guo, Ye Chun Ruan, Chi Chiu Wang, Gang Li, Hon Fai Chan, Xiaohu Zhang, Xiaohua Jiang

“…Mass spectrometry revealed a conserved set of proteins including THBS1 (thrombospondin 1), SERPINE1 (serpin family E member 1), ANXA1 (annexin A1), LOX (lysyl oxidase), and ITGB1 (integrin beta-1) which are involved in extracellular matrix (ECM) organization and wound healing, with the PI3K/AKT signaling pathway playing a central role. …”
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Best evidence summary for nutritional management of cancer patients with chyle leaks following surgery by Jie Zhou, Wentao Huang, Ya Hu, Fen Liu, Man Xu, Xiaoping Chen, Mingzhu Xin, Huiming Lu, Xia Zheng

“…However, the existing evidence on nutritional management for this patient cohort fails to provide actionable clinical guidance.AimThis study was aimed to establish an evidence-based framework for nutritional management, offering reliable basis for clinical nursing practice.MethodsUtilizing the “6S” mode, we conducted a systematic search of UpToDate, BMJ, Best Practice, Cochrane Library, Joanna Briggs Institute (JBI) Center for Evidence-Based Health Care Database, National Guideline Clearinghouse (NGC), Guidelines International Network (GIN), National Institute for Health and Care Excellence (NICE), Scottish Intercollegiate Guidelines Network (SIGN), Registered Nurses' Association of Ontario (RNAO), World Health Organization, Medlive, American Society for Parenteral and Enteral Nutrition (ASPEN), European Society for Clinical Nutrition and Metabolism (ESPEN), Web of Science, PubMed, Embase, CINAHL, China Biology Medicine (CBM), and China National Knowledge Infrastructure (CNKI) for all evidence on the nutritional management of postoperative coeliac leakage in cancer patients. …”
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Effects of Different Types of Cognitive Training on Cognitive Function, Brain Structure, and Driving Safety in Senior Daily Drivers: A Pilot Study by Takayuki Nozawa, Yasuyuki Taki, Akitake Kanno, Yoritaka Akimoto, Mizuki Ihara, Ryoichi Yokoyama, Yuka Kotozaki, Rui Nouchi, Atsushi Sekiguchi, Hikaru Takeuchi, Carlos Makoto Miyauchi, Takeshi Ogawa, Takakuni Goto, Takashi Sunda, Toshiyuki Shimizu, Eiji Tozuka, Satoru Hirose, Tatsuyoshi Nanbu, Ryuta Kawashima

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Effects of Hypoxia Stress on Biochemical Indices and Expression of Hypoxia-Related Genes in the Heart of Rainbow Trout (Oncorhynchus mykiss) by Jiuju MA, Jinqiang HUANG, Yongjuan LI, Shenji WU, Lu ZHAO, Yue ZENG

“…Under hypoxic stress, the rainbow trout were able to provide feedback regulation of hypoxic stress through the high expression pattern of hypoxic-related, which prevents the heart from being in a constant state of hypoxic stress, allowing the organism to quickly return to a stable state and perform its normal physiological function. …”
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The Efficacy and Safety of Elobixibat for the Elderly with Chronic Constipation: A Multicenter Retrospective Cohort Study by Akira Tomie, Naohisa Yoshida, Munehiro Kugai, Ryohei Hirose, Osamu Dohi, Ken Inoue, Kotaro Okuda, Takayuki Motoyoshi, Kohei Fukumoto, Yoshikazu Inagaki, Hiroyuki Yoriki, Yutaka Inada, Takashi Okuda, Daisuke Hasegawa, Kiyoshi Ogiso, Takaaki Murakami, Koichi Soga, Rafiz Abdul Rani, Norimasa Yoshida, Yoshito Itoh

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Evaluation of standardized training model for newly recruited nurses based on demand orientation and post competency (以教育需求评估和核心能力为理论框架的新入职护士规范化培训实践效果评价)... by LI Yun (李云), NIE Fang (聂芳), WANG Xin (王欣), ZHU Lizhen (祝丽珍)

“…Methods Totally 70 nurses recruited in 2017 were selected as control group by convenient sampling method, and their training, examination and management were organized by using a traditional training mode. The same method was adopted to select 69 nurses in 2018 as observation group, and a standardized training model based on demand orientation and post competence was established. …”
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Effects of autolytical fish protein hydrolysate on growth performance, survival rate, and hematological indices in farmed juvenile beluga, Huso huso by Ali Hosseinpour Zelaty

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The Effect of Chewing Simulation on Flexural Strength of Different Lithium Disilicate Ceramics by Alsulimani O, Yousief SA, Al-Dabbagh RA, Attar EA, Bukhary DM, Algamaiah H, Musawa K, Subahi A, Abuzinadah SH, Alhaddad AJ, Alqahtani WMS, Emam ANM, Alqhtani MA, Elmarakby AM

“…The ceramic surfaces were examined using SEM before and after loading.Statistical Analysis: Data were gathered, organized, and subjected to Shapiro–Wilk’s and Levene’s tests (p-value < 0.05), followed by analysis with Brown-Forsythe two-way ANOVA and Tamhane’s post hoc tests to assess group differences (p-value < 0.05).Results: There were significant statistical differences in the flexural strength values between the different brand groups before and after chewing simulation (p-value < 0.05). …”
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Multimorbidity latent classes in relation to 11-year mortality, risk factors and health-related quality of life in Malaysia: a prospective health and demographic surveillance syste... by Michelle M. C. Tan, Charlotte Hanlon, Graciela Muniz-Terrera, Tatiana Benaglia, Roshidi Ismail, Devi Mohan, Ann Breeze Joseph Konkoth, Daniel Reidpath, Pedro José M. Rebello Pinho, Pascale Allotey, Zaid Kassim, Matthew Prina, Tin Tin Su

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Development of a Sensitive Quantum Dot-Linked Immunoassay for the Multiplex Detection of Biochemical Markers in a Microvolumeric Format by Kalvaityte U, Bagdonas E, Kirdaite G, Kausaite-Minkstimiene A, Uzieliene I, Ramanaviciene A, Popov A, Butkiene G, Karabanovas V, Denkovskij J, Mobasheri A, Bernotiene E

“…Ursule Kalvaityte,1 Edvardas Bagdonas,1 Gailute Kirdaite,2 Asta Kausaite-Minkstimiene,3,4 Ilona Uzieliene,1 Almira Ramanaviciene,3,4 Anton Popov,3,4 Greta Butkiene,1,5 Vitalijus Karabanovas,1,5 Jaroslav Denkovskij,1 Ali Mobasheri,1,6– 8 Eiva Bernotiene1,9 1Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, LT-08406, Lithuania; 2Department of Personalised Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania; 3Department of Immunology and Bioelectrochemistry, State Research Institute Centre for Innovative Medicine, Vilnius, LT-08406, Lithuania; 4NanoTechnas - Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Vilnius, LT-03225, Lithuania; 5Biomedical Physics Laboratory, National Cancer Institute, Baublio 3b, Vilnius, LT-08406, Lithuania; 6Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Oulu, 90014, Finland; 7World Health Organization Collaborating Center for Public Health Aspects of Musculoskeletal Health and Aging, Université de Liège, Liège, B-4000, Belgium; 8Department of Joint Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China; 9Faculty of Fundamental Sciences, Vilnius Gediminas Technical University, Vilnius, LT-10223, LithuaniaCorrespondence: Eiva Bernotiene, Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Santariskiu G. 5, Vilnius, LT-08406, Lithuania, Tel +37068377130, Email eiva.bernotiene@imcentras.ltPurpose: For the diagnosis of various diseases, simultaneous sensitive detection of multiple biomarkers using low sample volumes is needed. …”
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Prevalence of daily fruit and vegetable intake by socio-economic characteristics, women’s empowerment, and climate zone: an ecological study in Latin American cities by Giovanna Valentino, Amy H. Auchincloss, Binod Acharya, Natalia Tumas, Nancy López-Olmedo, Ana Ortigoza, Mariana Carvalho de Menezes, María Fernanda Kroker-Lobos, Carolina Nazzal

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High-sensitivity, high-speed, broadband mid-infrared photodetector enabled by a van der Waals heterostructure with a vertical transport channel by Jianfeng Wu, Jialin Zhang, Ruiqi Jiang, Hao Wu, Shouheng Chen, Xinlei Zhang, Wenhui Wang, Yuanfang Yu, Qiang Fu, Rui Lin, Yueying Cui, Tao Zhou, Zhenliang Hu, Dongyang Wan, Xiaolong Chen, Weida Hu, Hongwei Liu, Junpeng Lu, Zhenhua Ni

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An Evidence summary of postoperative pain management in spinal surgery (脊柱外科术后患者疼痛管理的证据总结) by XIANG Tingting (向婷婷), ZHENG Su (郑苏), XIE Xiaomin (谢晓敏)

“…Results A total of 10 articles were selected, including 1 clinical decisions, 2 evidence summary, 5 guidelines, 1expert opinion, 1 expert consensus, best evidences were summarized from the 5 aspects of pain evaluation, intervention, monitoring, education and organization. Conclusion This study summarized the best evidence of postoperative pain management in spinal surgery, which provided evidence for clinical application. …”
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Occurrence of Alternaria Toxins, Ochratoxin A and Aflatoxins B1 in Green Arabic Coffee (Coffea arabica) in Saudi Arabia: Risk Assessment on HepG-2 Cell Line and Male Albino Rats by Ahmed Hashim Almusallam, Ahmed Mahmoud Ismail

“…The results demonstrated a notable decline in liver and kidney functions in all mycotoxins-treated rats. The studied organs (liver, kidney and spleen) exhibited significant damage, with the most severe alterations observed in the Mix1 and Mix2-treated group in comparison with the groups receiving individual treatment. …”
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A compilation of surface inherent optical properties and phytoplankton pigment concentrations from the Atlantic Meridional Transect by T. M. Jordan, G. Dall'Olmo, G. Tilstone, R. J. W. Brewin, F. Nencioli, R. Airs, C. S. Thomas, L. Schlüter

“…<p>In situ measurements of particulate inherent optical properties (IOPs) – absorption (<span class="inline-formula"><i>a</i>_p(<i>λ</i>)</span>), scattering (<span class="inline-formula"><i>b</i>_p(<i>λ</i>)</span>), and beam attenuation (<span class="inline-formula"><i>c</i>_p(<i>λ</i>)</span>) – are crucial for the development of optical algorithms that retrieve biogeochemical quantities such as chlorophyll <span class="inline-formula"><i>a</i></span>, particulate organic carbon (POC), and total suspended matter (TSM). …”
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