Evaluating metagenomics and targeted approaches for diagnosis and surveillance of viruses by Sarah Buddle, Leysa Forrest, Naomi Akinsuyi, Luz Marina Martin Bernal, Tony Brooks, Cristina Venturini, Charles Miller, Julianne R. Brown, Nathaniel Storey, Laura Atkinson, Timothy Best, Sunando Roy, Sian Goldsworthy, Sergi Castellano, Peter Simmonds, Heli Harvala, Tanya Golubchik, Rachel Williams, Judith Breuer, Sofia Morfopoulou, Oscar Enrique Torres Montaguth

“…Results Capture with the Twist CVRP increased sensitivity by at least 10–100-fold over untargeted sequencing, making it suitable for the detection of low viral loads (60 genome copies per ml (gc/ml)), but additional methods may be needed in a diagnostic setting to detect untargeted organisms. While untargeted ONT had good sensitivity at high viral loads (60,000 gc/ml), at lower viral loads (600–6000 gc/ml), longer and more costly sequencing runs would be required to achieve sensitivities comparable to the untargeted Illumina protocol. …”
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Glioma Image-Level and Slide-Level Gene Predictor (GLISP) for Molecular Diagnosis and Predicting Genetic Events of Adult Diffuse Glioma by Minh-Khang Le, Masataka Kawai, Kenta Masui, Takashi Komori, Takakazu Kawamata, Yoshihiro Muragaki, Tomohiro Inoue, Ippei Tahara, Kazunari Kasai, Tetsuo Kondo

“…The latest World Health Organization (WHO) classification of central nervous system tumors (WHO2021/5th) has incorporated molecular information into the diagnosis of each brain tumor type including diffuse glioma. …”
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Insights into ozone pollution control in urban areas by decoupling meteorological factors based on machine learning by Y. Qiu, X. Li, X. Li, W. Chai, Y. Liu, M. Song, X. Tian, Q. Zou, W. Lou, W. Zhang, J. Li, Y. Zhang

“…., NO<span class="inline-formula">_<i>x</i></span> and volatile organic compounds, VOCs). When meteorological conditions deteriorate, the atmosphere's capacity to cleanse pollutants decreases, leading to the accumulation of air pollutants. …”
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Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence by Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton-That

“…Together, these results establish that the BMC-mediated metabolism of ethanolamine is critical for fusobacterial virulence.IMPORTANCEThe oral anaerobe Fusobacterium nucleatum can spread to distal internal organs, such as the colon and placenta, thereby promoting the development of colorectal cancer and inducing preterm birth, respectively. …”
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Prevalence of overweight and obesity among preschool children in Hainan: a cross-sectional study in China's largest free-trade zone by Wei-Jia Wu, Wei-Jia Wu, Ping-Hao Chen, Ping-Hao Chen, Zhen-Ning Huang, Zhen-Ning Huang, Xue-Lu Lei, Xue-Lu Lei, Chen Wang, Chen Wang, Chun-hui Zhang, Chun-hui Zhang, Ping Wang, Ping Wang, Chui-can Huang, Qing Luo, Qing Luo, Li-Chun Fan, Li-Chun Fan

“…Our study assessed the prevalence of overweight and obesity among preschool children across Hainan Island using Chinese, World Health Organization (WHO), and International Obesity Task Force (IOTF) criteria. …”
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CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors by Chrystal Paulos, Mary Jo Turk, Megen C Wittling, Yina H Huang, Asmaa O Mohamed, David Tyler Boone, Shannon L Ferry, Melanie C Peck, Alicia M Santos, Haille E Soderholm

“…Unarmored CAR T cells expressed a stem-like phenotype in the tumor-draining lymph node and differentiated into CAR TCIRC memory cells in lymphoid organs and CAR TRM cells in the skin. In contrast, S233-armored CAR T cells exhibited an activated effector phenotype and differentiated inefficiently into CAR effector and central memory T cells. …”
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Biochemical, Histological, and Multi-Omics Analyses Reveal the Molecular and Metabolic Mechanisms of Cold Stress Response in the Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis... by Liqin Ji, Qing Shi, Chen Chen, Xiaoli Liu, Junxian Zhu, Xiaoyou Hong, Chengqing Wei, Xinping Zhu, Wei Li

“…The Chinese soft-shelled turtle (<i>Pelodiscus sinensis</i>), a type of warm-water reptile, is frequently chosen as the model animal to understand how organisms respond to environmental stressors. However, the responsive mechanism of <i>P. sinensis</i> to natural cold stress is unclear, especially in terms of metabolic pattern and molecular pathways. …”
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Understanding Dioxygen Activation in the Fe(III)-Promoted Oxidative Dehydrogenation of Amines: A Computational Study by Ricardo D. Páez-López, Miguel Á. Gómez-Soto, Héctor F. Cortés-Hernández, Alejandro Solano-Peralta, Miguel Castro, Peter M. H. Kroneck, Martha E. Sosa-Torres

“…Hydrogenation and dehydrogenation reactions are fundamental in chemistry and essential for all living organisms. We employ density functional theory (DFT) to understand the reaction mechanism of the oxidative dehydrogenation (ODH) of the pyridyl-amine complex [Fe^IIIL³]³⁺ (L³, 1,9-bis(2′-pyridyl)-5-[(ethoxy-2″-pyridyl)methyl]-2,5,8-triazanonane) to the mono-imine complex [Fe^IIL⁴]²⁺ (L⁴, 1,9-bis(2′-pyridyl)-5-[(ethoxy-2″-pyridyl)methyl]-2,5,8-triazanon-1-ene) in the presence of dioxygen. …”
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Weighted EHR-based prevalence estimates for hypertension at the state and local levels in Louisiana by Wenjun Li, Meng Zhang, Jie Cheng, Sandra L. Jackson, Adam S. Vaughan, Michael Klompas, Thomas W. Carton, Elizabeth Nauman, Lee Mendoza, Arun Adhikari, Jeanie Donovan, Katherine H. Hohman

“…These estimates can provide public health organizations with timely, accurate, and local information. …”
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Association of coronary revascularisation after physician-referred non-invasive diagnostic imaging tests with outcomes in patients with suspected coronary artery disease: a post ho... by Takao Kato, Moriaki Inoko, Naoya Matsumoto, Yukari Uemura, Masanao Naya, Mitsuru Momose, Satoshi Hida, Takao Yamauchi, Takatomo Nakajima, Eriko Suzuki, Tohru Shiga, Nagara Tamaki

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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms by Irina Tiganova, Yulia Zhizhimova, Eteri Tolordava, Elena Makarova, Natalia Shevlyagina, Alexander Barmashov, Maria Baryshnikova, Vladimir Zhukhovitsky, Yulia Romanova

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Remote Monitoring of Chemotherapy-Induced Peripheral Neuropathy by the NeuroDetect iOS App: Observational Cohort Study of Patients With Cancer by Ciao-Sin Chen, Michael P Dorsch, Sarah Alsomairy, Jennifer J Griggs, Reshma Jagsi, Michael Sabel, Amro Stino, Brian Callaghan, Daniel L Hertz

“…MethodsThe NeuroDetect app (Medable Inc) includes subjective EORTC (European Organization for Research and Treatment of Cancer) Quality of Life Questionnaire (QLQ)–20-item scale (CIPN20) and 6 objective functional assessments that use smartphone sensors to mimic neurological examinations, such as walking, standing, and manual dexterity tests. …”
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Dairy cows' responses to 2 separation methods after 3 months of cow-calf contact by Anina Vogt, Susanne Waiblinger, Rupert Palme, Uta König von Borstel, Kerstin Barth

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L’alimentation hydraulique de Saint-Romain-en-Gal (Rhône), quartier de Vienne antique (Isère) by Laurence Brissaud, Jean-Luc Prisset

“…It is hoped that such studies could be carried out on the left bank to find out about hydraulic organization in the town centre and the links that connected aqueducts on the left bank and pressurised water systems on the right bank.…”
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Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples by Borremans, Benny, Falvo, Caylee A, Crowley, Daniel E, Hoegh, Andrew, Lloyd-Smith, James O, Peel, Alison J, Restif, Olivier, Ruiz-Aravena, Manuel, Plowright, Raina K

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SECOND WAVE AND PANDEMIC SITUATION OF COVID-(2020-2021) IN BANGLADESH by Ahasan Ullah Khan, Rumana Akter, Foyj Ullah Khan, Shakhera Khanom, Anayat Ullah Khan, Ayesha Shiddika Afsana

“… Background: In Bangladesh, the Institute of Epidemiology, Disease Control and Research (IEDCR) reported the first COVID-19 positive patients in the country on March 8, 2020. The world health organization (WHO) declared a COVID-19 epidemic on March 11, 2020. …”
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Enhancing sustainable solid waste management through separate source collection by O. Arabiyat, J.T. Al-Bakri, F. Kölsch, S. Al-Omari, H. Aladwan

“…A significant amount of municipal solid waste (60 percent) has an organic composition, while recyclable waste constitutes about 12.5 percent of the total municipal solid waste. …”
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Un service de table en bronze et argent soigneusement rangé dans une cave à Reims/Durocortorum by Michaël Brunet, Fabienne Médard, Magalie Cavé, Stéphane Sindonino

“…The study of the crockery organization alongside the textile data allows us to propose an overall reconstruction of the deposit. …”
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Pengukuran Kepuasan Pengguna E-Learning Menggunakan Metode Evaluasi Heuristik dan System Usability Scale by Emi Iryanti, La Ode Mohamad Zulfiqar, Sri Suning Kusumawardani, Indriana Hidayah

“…In the usability evaluation using HE, the selected evaluators are five user experts who are experts in the field of usability (three people) who are experts in the field of IT and learning development (two people), while the scope of evaluation in this study is the login process, edit profile, lecture organization, and lecture activities. While the evaluation using the SUS questionnaire obtained a score of 63.3 (grade C-) with 162 respondents. …”
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United by Sports? Key Factors affecting Sports Participation in a Sports-based Initiative to Promote Social Integration in Segregated Communities by Anna Boemmel, Matthias Buser, Thomas Persson

“…Acknowledging this challenge, the Swedish government, the Swedish Sports Confederation, and sports organizations have invested in sports to promote integration. …”
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