Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma by Kai Zhang, Kai Zhang, Luyao Wang, Huili Chen, Lili Deng, Mengling Hu, Ziqiang Wang, Yiluo Xie, Chaoqun Lian, Xiaojing Wang, Xiaojing Wang, Jing Zhang

“…However, the effect of nucleotide metabolism on LUAD remains to be thoroughly investigated.MethodsTranscriptomic and clinical data of LUAD were downloaded and organized from TCGA and GEO databases. Genes related to nucleotide metabolism were downloaded from the Msigdb database. …”
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Biodegradation of Phenol at High Initial Concentration by <i>Rhodococcus opacus</i> 3D Strain: Biochemical and Genetic Aspects by Tatiana O. Anokhina, Tatiana Z. Esikova, Valentina N. Polivtseva, Nataliya E. Suzina, Inna P. Solyanikova

“…Phenolic compounds are an extensive group of natural and anthropogenic organic substances of the aromatic series containing one or more hydroxyl groups. …”
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Attitudes toward healthy nutrition in Germany — results from an online-representative cross-sectional survey by Etienne Hanslian, Etienne Hanslian, Julia Katharina Schiele, Julia Katharina Schiele, Michael Jeitler, Andreas Michalsen, Andreas Michalsen, Manfred Wischnewsky, Manfred Wischnewsky, Maximilian Andreas Storz, Benno Brinkhaus, Miriam Ortiz, Mike R. Sigl, Rasmus Hoffmann, Judith Lehmann, Daniela A. Koppold, Daniela A. Koppold, Daniela A. Koppold, Daniela A. Koppold, Christian S. Keßler, Christian S. Keßler

“…Approximately 18% of participants predominantly or exclusively bought organic foods. Interestingly, one third of participants indicated a willingness to adopt a more plant-based diet if recommended by physicians or scientists.ConclusionThis online representative survey revealed significant associations between nutrition and sociodemographic aspects. …”
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How resistant is anammox biofilm against antibiotics: A special insight into anammox response towards fluoroquinolones by Faysal-Al Mamun, Rohit Kumar, Kelvin Ugochukwu Anwuta, Sovik Das, Madis Jaagura, Koit Herodes, Tetyana Kyrpel, Agnieszka Fiszka Borzyszkowska, Anna Zielińska-Jurek, Zane Vincevica-Gaile, Juris Burlakovs, Andrey E. Krauklis, Mohamad Nor Azra, Md Salauddin, Jiexi Zhong, Taavo Tenno, Kai Bester, Ivar Zekker

“…Elevated concentrations of pharmaceutically active compounds (PhACs) in the water bodies are posing a serious threat to the aquatic microbiota and other organisms. In this context, anaerobic ammonium oxidizing (anammox) bacteria carry a great potential to degrade PhACs through their innate metabolic pathways. …”
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Multi-omics elucidates the kidney damage caused by aquatic Cu via the gut-kidney axis in ducks by Mingcai Duan, Jinyu Liu, Zhaoxia Cai, Li Chen, Yong Tian, Wenwu Xu, Tao Zeng, Tiantian Gu, Lizhi Lu

“…Excessive intake of Cu exists harmful effects on organisms. However, whether excessive Cu intake induces kidney function damage by gut microbiota regulation remains unclear. …”
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Comparative cytogenetics of anembryonic pregnancies and missed abortions in human by T. V. Nikitina, E. A. Sazhenova, E. N. Tolmacheva, N. N. Sukhanova, S. A. Vasilyev, I. N. Lebedev

“…Thus, although the frequencies of some types of chromosomal pathology differ between AP and MA, the total frequency of chromosomal abnormalities in AP is not increased compared to MA, which indicates the need to search for the causes of AP at other levels of the genome organization, including microstructural chromosomal rearrangements, monogenic mutations, imprinting disorders, and epigenetic abnormalities.…”
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Spatiotemporal Assessment of PM2.5 Exposure of a High-risk Occupational Group in a Southeast Asian Megacity by Jarl Tynan Collado, Jose Gabriel Abalos, Imee de los Reyes, Melliza T. Cruz, Gabrielle Frances Leung, Katrina Abenojar, Carlos Rosauro Manalo, Bernell Go, Christine L. Chan, Charlotte Kendra Gotangco Gonzales, James Bernard B. Simpas, Emma E. Porio, John Q. Wong, Shih-Chun Candice Lung, Maria Obiminda L. Cambaliza

“…From all 15-second measurements obtained, the mean concentration of PM2.5 is 36.4 µg m−3, seven times greater than the mean annual guideline value (5.0 µg m−3) set by the World Health Organization (WHO). Elevated levels of PM2.5 were observed at key transportation microenvironments (TMEs) such as a transport terminal and near a shopping mall. …”
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Bronchiectasis Exacerbation Increases the Risk of Adverse Renal Outcomes—Results From a Large Territory‐Wide Cohort Study by Wang Chun Kwok, Chung Ki Tsui, Leung Sze Him Isaac, Chun Ka Emmanuel Wong, Terence Chi Chun Tam, James Chung Man Ho, Desmond Yat Hin Yap

“…ABSTRACT Introduction Bronchiectasis exacerbation (BE) is associated with unfavorable sequelae in other organs such as the cardiovascular system; data regarding its impact on adverse term renal outcomes, however, is lacking. …”
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The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

“…Testosterone plays an important role in the intracellular homeostasis of the heart. Quercetin is an organic substance belonging to the flavonoid family with a wide range of medicinal properties. …”
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Roaming the Seas—Assessing Marine Invertebrate Biodiversity Along Salinity Gradients With Zooplankton and eDNA Metabarcoding by Alica Ohnesorge, Uwe John, Lucie Kuczynski, Stefan Neuhaus, Kingsly Chuo Beng, Bernd Krock, Silke Laakmann

“…The detection of holoplanktonic species from SE eDNA provided evidence for sinking of eDNA particles, dead organisms or the presence of resting eggs. Our study confirms the value of metabarcoding to identify the North Sea and Baltic Sea invertebrates and underscores the importance of combining multiple approaches to understand invertebrate biodiversity and its change in the marine realm.…”
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Ambient PM2.5 Temporal Variation and Source Apportionment in Mbarara, Uganda by Silver Onyango, Crystal M. North, Hatem A. Ellaithy, Paul Tumwesigye, Choong-Min Kang, Vasileios Matthaios, Martin Mukama, Nuriat Nambogo, J. Mikhail Wolfson, Stephen Ferguson, Stephen Asiimwe, Lynn Atuyambe, Data Santorino, David C. Christiani, Petros Koutrakis

“…We compared our estimates to publicly available levels in Kampala, and to World Health Organization (WHO) air quality guidelines. We characterized the leading PM2.5 sources in Mbarara using x-ray fluorescence and positive matrix factorization. …”
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Comparative analysis of anticoagulant influence on PMI estimation based on porcine blood metabolomics profile measured using GC-MS by Patrycja Mojsak, Paulina Samczuk, Paulina Samczuk, Paulina Klimaszewska, Michal Burdukiewicz, Michal Burdukiewicz, Jaroslaw Chilimoniuk, Krystyna Grzesiak, Krystyna Grzesiak, Karolina Pietrowska, Justyna Ciborowska, Anna Niemcunowicz-Janica, Adam Kretowski, Adam Kretowski, Michal Ciborowski, Michal Ciborowski, Michal Szeremeta

“…Our study aimed to identify metabolites dependent on the EDTA addition and time (taking into account the biodiversity of the studied organism) and those that are time−dependent but resistant to the addition of an anticoagulant.MethodsThe experiment was performed on blood samples collected from 16 animals (domestic pig, breed: Polish Large White), 8 with and 8 without EDTA addition. …”
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First Measurements of Ambient PM2.5 in Kinshasa, Democratic Republic of Congo and Brazzaville, Republic of Congo Using Field-calibrated Low-cost Sensors by Celeste McFarlane, Paulson Kasereka Isevulambire, Raymond Sinsi Lumbuenamo, Arnold Murphy Elouma Ndinga, Ranil Dhammapala, Xiaomeng Jin, V. Faye McNeill, Carl Malings, R. Subramanian, Daniel M. Westervelt

“…We estimated an average annual PM2.5 concentration of 43.5 µg m−3 in Kinshasa for 2019, which exceeds the World Health Organization (WHO)’s Interim Target 1 (10 µg m−3) by 4 times. …”
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Childhood wasting and associated factors in Africa: evidence from standard demographic and health surveys from 35 countries by Tadesse Tarik Tamir, Alebachew Ferede Zegeye, Belayneh Shetie Workneh, Mohammed Seid Ali, Almaz Tefera Gonete, Masresha Asmare Techane, Mulugeta Wassie, Alemneh Tadesse Kassie, Medina Abdela Ahmed, Sintayehu Simie Tsega, Yilkal Abebaw Wassie, Berhan Tekeba, Enyew Getaneh Mekonen

“…The World Health Organization’s Global Nutrition Target aims to reduce childhood wasting to less than 5% in over half of low- and middle-income countries by 2025. …”
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Predicting High-Grade Acute Urinary Toxicity and Lower Gastrointestinal Toxicity After Postoperative Volumetric Modulated Arc Therapy for Cervical and Endometrial Cancer Using a No... by Tianyu Yang, Zhe Ji, Runhong Lei, Ang Qu, Weijuan Jiang, Xiuwen Deng, Ping Jiang

“…This study aims to retrospectively analyze the relationship between dosimetric parameters of organs at risk (OARs) and acute toxicities and provide suggestions for the dose constraints. (2) Methods: A total of 164 postoperative cervical and endometrial cancer patients were retrospectively analyzed, and the endpoints were grade ≥ 2 acute urinary toxicity (AUT) and acute lower gastrointestinal toxicity (ALGIT). …”
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Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective... by Itske Fraterman, Lucia Sacchi, Henk Mallo, Valentina Tibollo, Savannah Lucia Catherina Glaser, Stephanie Medlock, Ronald Cornet, Matteo Gabetta, Vitali Hisko, Vadzim Khadakou, Ella Barkan, Laura Del Campo, David Glasspool, Alexandra Kogan, Giordano Lanzola, Roy Leizer, Manuel Ottaviano, Mor Peleg, Konrad Śniatała, Aneta Lisowska, Szymon Wilk, Enea Parimbelli, Silvana Quaglini, Mimma Rizzo, Laura Deborah Locati, Annelies Boekhout, Lonneke V van de Poll-Franse, Sofie Wilgenhof

“…HRQoL data were measured with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 at baseline (T0), 3 months (T1), and 6 months (T2) after start of treatment. …”
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Enhancing CO₂ selectivity in MOFs through a dual-ligand strategy: Experimental and theoretical insights by Amir Kazemi, Akram Karbalaee Hosseini, Mahyar Ashourzadeh Pordsari, Mohsen Tamtaji, Saber Keshavarz, Faranak Manteghi, Azadeh Tadjarodi, Ahad Ghaemi, Sohrab Rohani, William A. Goddard

“…Carbon dioxide (CO₂) is a primary greenhouse gas, playing a significant role in global warming and climate change. In response, metal-organic frameworks (MOFs) have emerged as effective materials for CO₂ capture. …”
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The Beneficial Application of Turmeric (Curcuma longa L.) on Health and Egg Production, in Layers: A Review by Saade Abdalkareem Jasim, Aiman Mohammed Baqir Al‐Dhalimy, Maryam Zokaei, Shadi Salimi, Mohammed Jawad Alnajar, Abhinav Kumar, Enas R. Alwaily, Ahmed Hussein Zwamel, Soura Alaa Hussein, Majid Gholami‐Ahangaran

“…The mechanisms underlying these effects involve the antioxidant properties of turmeric, which protect the reproductive organs, enhance ovarian function and improve reproductive performance. …”
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School-to-work and school-to-university transition and health inequalities among young adults: a scoping review by Matthias Richter, Nico Dragano, Benjamin Wachtler, Stephanie Hoffmann, Max Herke, Katharina Diehl, Marvin Reuter, Paula Mayara Matos Fialho, Maria-Inti Metzendorf, Wiebke Schüttig, Christian Deindl, Sarah Schleberger, Claudia R Pischke

“…Ovid MEDLINE and Web of Science, and websites of the International Labour Organization and National Institute for Occupational Safety and Health were searched, using a predetermined search strategy. …”
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Seed delivery system in northeastern Democratic Republic of Congo: characteristics, stakeholders mapping and challenges towards building a well-functioning seed system under humani... by Jean M. Mondo, Adrien B. Ndeko, Rodrigue B. Ayagirwe, Henri M. Matiti, Chance Bahati, René M. Civava

“…The cash flow in the seed sector was high owing to high seed demands from humanitarian organizations and farmer support structures, estimated at ∼1.5 million US$ in 2022 for the top three commercial seed commodities (common beans, maize and peanuts). …”
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