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Ebola Virus and SARS-CoV-2: Similarities and Differences
Published 2020-07-01“…Ebola virus and the novel coronavirus of 2019, SARS-CoV-2 (severe acute respiratory syndrome coronavi- rus 2) share many similarities in origin although transmission, morbidity and mortality are vastly different. …”
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Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis
Published 2020-12-01“…COVID-19 is the deadly respiratory disease of the century caused by new type unknown origin Coronavirus. The recent effort of the word researchers is toward finding the origin of the virus. …”
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Clinical characteristics of pediatric patients with SARS-CoV-2 infection. Cienfuegos, 2020-2021
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Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
Published 2022-01-01“…Ionised active water S-100® has been proposed as an original solution for use in dermocosmetics and for the treatment of wounds such as burns and atopic dermatitis. …”
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An Overview on the Role of Relative Humidity in Airborne Transmission of SARS-CoV-2 in Indoor Environments
Published 2020-07-01“…Abstract COVID-19 disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China and spread with an astonishing rate across the world. …”
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Protective potential of structural proteins of the SARS-CoV-2 virus in protecting against COVID-19
Published 2024-12-01“…Due to the constant change in circulating variants of the SARS-CoV-2 virus, the decrease in the effectiveness of the vaccines with the original antigen composition against new variants of the virus and the continuing high incidence of COVID-19, it is necessary to continuously monitor the effectiveness of vaccines against new variants of the virus and promptly update the antigen composition of vaccines when a decrease in effectiveness is detected.…”
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Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections?
Published 2025-02-01“…We propose that the elevated levels of VEGF-A observed during HIV/SARS-CoV-2 co-infection originate predominantly from activated immune cells due to the upregulation of HIF-1α by damaged endothelial cells. …”
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Long-term effects of SARS-CoV-2 infection and vaccination in a population-based pediatric cohort
Published 2025-01-01“…In a subgroup (n = 259) SARS-CoV-2 antibody serology was further investigated. 789 participants of the original CorKID study cohort (n = 2.121; 37.2%) were included. 67.9% reported at least one SARS-CoV2 infection. 46.6% had received one or more SARS-CoV-2 vaccinations. …”
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Computational analysis of SARS-CoV-2, SARS-CoV, and MERS-CoV genome using MEGA
Published 2020-09-01“…The novel coronavirus pandemic that has originated from China and spread throughout the world in three months. …”
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Is It Scaly Anteater or Bat A Real Origin of The 2019-Novel CoV: A Probable Hypothesis?
Published 2020-04-01“…Thus, necessitates a very rapid active surveillance using accurate method to find the original host where the 2019nCoV emerged. This will help in further understanding and creating a better approach to control the spread of SARS-CoV-2 outbreak. …”
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mRNA vaccines with RBD mutations have broad-spectrum activity against SARS-CoV-2 variants in mice
Published 2025-01-01“…Abstract The emergence of SARS-CoV-2 variants with defined mutations that enhance pathogenicity or facilitate immune evasion has resulted in a continual decline in the protective efficacy of existing vaccines. …”
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Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies.
Published 2025-01-01“…Previously, we designed a next-generation synthetic humanized nanobody (Nb) phage display library and demonstrated that this library could be used to rapidly identify highly specific and potent neutralizing heavy chain-only antibodies (HCAbs) with prophylactic and therapeutic efficacy in vivo against the original SARS-CoV-2. In this study, we used a combination of high throughput screening and machine learning (ML) models to identify HCAbs with potent efficacy against SARS-CoV-2 viral variants of interest (VOIs) and concern (VOCs). …”
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Evaluation of IgG binding capability to SARS-CoV-2 variants in early COVID-19 convalescent sera using an indirect ELISA
Published 2025-02-01“…Many SARS-CoV-2 variants are considered to have potential to escape from the host immune system. …”
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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor
Published 2025-02-01“…Background: Accumulating evidence suggests that the receptor binding domain (RBD) of the SARS-CoV-2 Omicron variant has several times more binding affinity to the human angiotensin-converting enzyme 2 (ACE2) receptor compared to the RBD of the original Covid-19 strain. …”
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Functional heterogeneity of mesenchymal stem cells and their therapeutic potential in the K18-hACE2 mouse model of SARS-CoV-2 infection
Published 2025-01-01“…This study aimed to evaluate the biological characteristics of MSCs from different tissue origins, selecting the most promising line for further validation in a K18-hACE2 mouse model of SARS-CoV-2 infection. …”
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The R203M and D377Y mutations of the nucleocapsid protein promote SARS-CoV-2 infectivity by impairing RIG-I-mediated antiviral signaling.
Published 2025-01-01“…However, its biological function in viral evolution is not well understood. SARS-CoV-2 N protein mutations were analyzed in Delta, Omicron, and original strains. …”
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COVID-19: Understanding the New Variants of Concern
Published 2022-12-01“… The novel coronavirus, SARS-CoV-2, part of the Coronaviridae family, was discovered in December 2019 in China. …”
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Does the COVID-19 XBB Omicron subvariant signal the beginning of the end of the pandemic?
Published 2024-12-01“…This is to be expected in the natural evolution of a virus in a population highly vaccinated with a vaccine targeting the spike protein of the original Wuhan strain of the virus. This review explores the important implications of the rising prevalence of the SARS-CoV-2 Omicron subvariant for public health in Singapore and beyond.…”
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A Rare Cutaneous Manifestation: Leukocytoclastic Vasculitis after Pfizer-BioNTech COVID-19 Vaccination
Published 2022-01-01“…There is growing evidence that vaccines against SARS-CoV-2 can cause various skin reactions, many of which have autoimmune origins. …”
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