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5361
Danggui-Shaoyao-San Can Ameliorate Alzheimer’s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology
Published 2025-02-01“…Kai-Xin Zhang,1 Ji-Wei Zhang,2 Yan-Hong Jiang,1 Yi-Ran Wang,1 Zhen-Ling Liu,1 Peng-Li Ding,1 Xiang-Ying Wang,1 Wen-Qiang Cui,3 Xiang-Qing Xu,3,* Ya-Han Wang3,* 1First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2College of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 3Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiang-Qing Xu, Ya-Han Wang; Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China, Email happyxiangqing@163.com; sdwangyahan@sina.comBackground: Danggui-Shaoyao-San (DSS) is a traditional Chinese medicine prescription with a history of nearly 2000 years, originally widely used for gynecological diseases, and in recent years research has found that DSS also has a good therapeutic effect on Alzheimer’s disease (AD).Purpose: The objective is to investigate the metabolic components of the DSS in the blood and the potential mechanisms for AD.Materials and Methods: Liquid chromatography‒mass spectrometry (LC-MS) combined with gas chromatography‒mass spectrometry (GC-MS) based non-targeted metabolomics were used to conduct in-depth research. …”
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5362
Interventions for SARS-CoV-2 prevention among Jailed adults: A network-based modeling analysis
Published 2025-06-01“…Background: Airborne pathogens present challenges in settings like jails or prisons with a high density of contacts. The state of Georgia has the highest percentage of its citizens under correctional supervision in the United States. …”
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5363
Novos olhares para os estudos da tradução espanholportuguês no século XXI: uma abordagem a partir dos estudos descritivos
Published 2024-12-01“…A teoria e prática primordialmente logocêntrica dava espaço à escritura desestruturada do teórico franco-magrebino, cuja base está na desconstrução do texto com o Outro, o que teria profundas consequências na relação entre texto original e traduzido – ou entre textos pertencentes a diferentes aqui e agora. …”
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5364
Mycotoxilogical monitoring. Part 2. Wheat, barley, oat and maize grain
Published 2020-06-01“…These data support the need of their introduction in the group of regulated substances significant for public health. Original monitoring data systematized and summarized in the paper are given in electronic format in section Additional materials.Part 1: Veterinary Science Today. 2020; 1 (32): 60–65. …”
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5365
Assessing water and energy fluxes in a regional hydrosystem: case study of the Seine basin
Published 2022-12-01“…In this paper, one of the first attempts to jointly model water and energy fluxes with a special focus on both surface and groundwater at the regional scale is proposed on the Seine hydrosystem (78,650 km$^{2}$), which overlays one of the main multi-aquifer systems of Europe.This study couples the SVAT model ORCHIDEE and the process-based hydrological–hydrogeological model CaWaQS, which describes water fluxes, via a one-way coupling approach from ORCHIDEE toward CaWaQS based on the blueprint published by [de Marsily et al., 1978]. An original transport library based on the resolution of the diffusion/advection transport equation was developed in order to simulate heat transfer in both 1D-river networks and pseudo-3D aquifer systems. …”
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5366
AHP Approach To Developing a New Natural Toothpaste Product
Published 2024-09-01“…Strategies include targeted marketing, loyalty programs, and strategic partnerships, ensuring a comprehensive and data-driven approach to reach and engage target audiences. Originality/value (State of the art): The AHP facilitates complete review, data-driven planning, and commercial viability for commercialization strategy. …”
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5367
Levels, Chemical Compositions, and Sources of PM2.5 of Rural and Urban Area under the Impact of Wheat Harvest
Published 2021-04-01“…Additionally, we found high geo-accumulation index (Igeo) values for crustal elements at both sampling sites, indicating that the dust emissions originated from the WH. Between DWH and AWH, the share of soil dust in the PM2.5 decreased from 21.3% to 7.98% and from 9.40% to 6.75% at ARS and UA, respectively. …”
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5368
Phylogeographic breaks and how to find them: An empirical attempt at separating vicariance from isolation by distance in a lizard with restricted dispersal
Published 2023-08-01“…Main conclusions: The genetic diversity of A. erythrurus originates from a mix of IBD and vicariance, which were difficult to distinguish, and resulted in similar levels of mitochondrial differentiation. …”
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5369
Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer
Published 2025-02-01“…Methods We performed targeted DNA sequencing on tumor specimens and conducted bulk RNA transcriptome analysis on 53 multiple nodules originating from 26 lung cancer patients. The multiple nodules from the same patient was determined as major nodule and minor nodule. …”
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5370
Effects of Brackish Water with Different Sodium-Potassium Ratios on Soil Water-Salt Characteristics and Winter Wheat Growth
Published 2024-12-01“…[Conclusion] In summary, irrigation using 4 dS/m brackish water changed the original water-salt characteristics of the soil, caused salts to accumulate in the soil and promoted winter wheat growth in the short term. …”
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5371
How Organizational Citizenship Behavior Stimulant: Transformational Leadership Identification Model Approaches
Published 2024-09-01“…This condition can trigger an increase in individual performance which will ultimately improve overall organizational performance. Originality/value (State of the art): The study's intriguing conclusion is that there is no significant relationship between work satisfaction and OCB. …”
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5372
L’alimentation hydraulique de Saint-Romain-en-Gal (Rhône), quartier de Vienne antique (Isère)
Published 2023-12-01“…It marked the northern limit of the original town, which grew at the foot of steep hills. …”
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5373
Rancang Bangun Aplikasi Berbasis Android untuk Perbaikan Kualitas Citra Tanaman Atas Perbedaan Spesifikasi Kamera Smartphone pada Prediksi Kandungan Pigmen Fotosintesis Secara Real...
Published 2022-12-01“…The variation of pigment content prediction with 3 different smartphone types on the same leaf object can be reduced by 87% after the original image is corrected with PLSR. …”
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5374
INSTRUMENT ASSESSMENT IN STUDENT LEARNING OUTCOME FOR FACTUAL AND CONCEPTUAL HOTS ON SCIENCE EDUCATION
Published 2024-04-01“…Specifically, the study identified 15 out of the original 20 items that met the criteria for validity and reliability. …”
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5375
Automatic MRI Lymph Node Annotation From CT Labels
Published 2025-01-01“…The algorithm has three steps: 1) unsupervised deformable image translation-based registration of MRI to CT image, producing registered MRI; 2) annotating lymph nodes in registered MRI with the available CT labels; and 3) deregistration of registered annotated MRI back to the original shape of MRI. The translation-based registration model for the algorithm’s first and third steps uses a discriminator-free StyleGAN2 translation network and a deformable image registration network with a U-Net-inspired architecture. …”
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5376
Anatomy, histology, and morphology of fish gills in relation to feeding habits: a comparative review of marine and freshwater species
Published 2025-02-01“…The gill arch carries additional structures, such as the air-breathing dendritic organ of the catfish, located in the suprabranchial chamber caudodorsal to the gills and composed of two main parts: small and large ones originated by main stems from the second and fourth-gill arches, respectively. …”
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5377
Esclarecimiento de Heráldica Eclesiástica y nombre completo del Cardenal Belluga y Moncada y del escudo radicado en la antigua casa de administración de sus Pías Fundaciones en Dol...
Published 2024-12-01“…Dicha Casa se encontraba localizada en la Villa de Nuestra Señora de los Dolores (denominación original que en otro lugar tiempo atrás se solicitó fuese rehabilitada y que aquí se reitera vivamente), hoy conocida simplemente por Dolores, en la provincia de Alicante, cuyo capital principal con el que se pretendió su iniciación lo ha constituido la inquietud por lo propio, y su desenlace, entre otros, vino producido por el hallazgo llevado a cabo en el Archivo Histórico Municipal del Ayuntamiento de Alicante de una fotografía realizada en el año 1947 al monolito con busto del Cardenal Belluga y Moncada (sito en plaza homónima), en la que con gran nitidez se pueden observar para su examen las armas heráldicas que motivan este trabajo.…”
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5378
Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease
Published 2025-02-01“…This subpopulation simultaneously expressed characteristic markers of peripheral blood monocytes, suggesting that these cells may originate from peripheral blood monocytes, thereby triggering neuroinflammation through the ferroptosis pathway. …”
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5379
Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes
Published 2025-02-01“…This compound has demonstrated similar contraceptive and steroidogenic properties as the original extract from S. tuberculatiformis. Additionally, Compound A has shown potent anti-inflammatory and anti-cancer effects in skin, raising the question of whether the S. tuberculatiformis extract might exhibit similar properties. …”
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5380
Accurate phenotype-to-genotype mapping of high-diversity yeast libraries by heat-shock-electroporation (HEEL)
Published 2025-02-01“…However, one major obstacle to creating accurate computer-based models is the current abundance of low-quality phenotypic measurements originating from numerous high-throughput but low-resolution assays. …”
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