Do continuous glucose monitoring (CGM) metrics predict macrovascular and microvascular complications in diabetes? The FACULTY protocol of a retrospective real-world cohort study by Eric Vicaut, Ramzi A Ajjan, J Seufert, Gérard de Pouvourville, Emmanuel Cosson, Laure Carcaillon-Bentata, Tadej Battelino, Patrick Blin, Fleur Levrat-Guillen, Michael Joubert

“…This will have an impact on routine clinical practice by setting targets for the different glycaemic markers, based on robust outcome data, thus helping to optimise glucose management in diabetes.Ethics and dissemination The study data-collection protocol is approved by the French National Commission for Informatics and Liberties, including approval from the Comité Ethique et Scientifique pour les Recherches, les Etudes et les Evaluations dans le domaine de la Santé. …”
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Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis by Lan Gao, Susan Brumby, Crystal Man Ying Lee, George Mnatzaganian, Suzanne Robinson, Helen Brown, Rachel Huxley, Anna Peeters, Dan Xu, James Boyd, Sean Randall, Adrienne O’Neil, Sangita Shakya, Sarah Gauci, Anita Shrestha, James Lucas

“…Exploring advanced costing methods such as time-driven activity-based costing can optimise resource allocation and identify opportunities to reduce unnecessary costs and cost disparities.PROSPERO registration number CRD42023412044.…”
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Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review by Annika Smith, Aidin Karahasan, Deborah Yi, Sanjay Yapabandara, James Elhindi, Pablo Fernandez-Penas, Clara Chow, Sarah Zaman

“…Further research in larger cohorts is needed to elucidate the benefits, if any, of biologic therapy on cardiometabolic parameters in individuals with psoriasis, in order to optimise care for this vulnerable cohort.…”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester-A primary cohort study with a scoping review. by Laura Ormesher, Jessica Catchpole, Linda Peacock, Heather Pitt, Anastasia Fabian-Hunt, Dexter Hayes, Claudia Popp, Jason M Carson, Raoul van Loon, Lynne Warrander, Karli Büchling, Alexander E P Heazell

“…Further work is needed to optimise the safety of prone positioning in pregnancy.…”
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Rearing mealworm larvae with wheat, barley or maize grains as main source of nutrients in unbalanced or balanced substrates by D. Plonquet, G. Fondevila, M. Fondevila

“…Feeding conditions of mealworm (T. molitor) larvae for livestock nutrition need to be optimised. The effects of the cereal offered as main nutrient source on growth performance and composition of T. molitor larvae were evaluated. …”
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PRACTICAL TRAINING OF OFFICERS OF THE STATE FIRE SERVICE THROUGH GAME-BASED LEARNING by V. V. Bulgakov, A. A. Lazarev, E. P. Konovalenko, T. A. Mochalova

“…However, in a technologically developed society, there is a contradiction between the increased requirements to young officers’ competencies and the impossibility to achieve a proper complex of graduates’ characteristics by providing education through only standard traditional techniques, which continue to be prevalent in higher education and ensure optimisation of professional activity in general.The aim of the present publication was to present the developed methodology of game-based learning for training of cadets of educational organisations of higher education of the EMERCOM of Russia. …”
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Skeletal Status, Body Composition, and Glycaemic Control in Adolescents with Type 1 Diabetes Mellitus by Elzbieta Wierzbicka, Anna Swiercz, Pawel Pludowski, Maciej Jaworski, Mieczyslaw Szalecki

“…Their recognition can be crucial in directing strategies to optimise metabolic control and improve diabetes management for bone development and maintenance in adolescents with T1DM.…”
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Corneal Clarity and Visual Outcomes after Small-Incision Lenticule Extraction and Comparison to Femtosecond Laser-Assisted In Situ Keratomileusis by Apostolos Lazaridis, Konstantinos Droutsas, Walter Sekundo, Michael Petrak, Stephan Schulze

“…CD was evaluated at 3 optically relevant, concentric radial zones (0–2 mm, 2–6 mm, and 0–6 mm annulus) around the corneal apex and at 3 different anatomical corneal layers (anterior, central, and posterior). …”
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Investigation of Borrow Pit TEA28 BP3, Fenstanton, Cambridgeshire, UK by W.A. Boismier, E. Allison, C. Ardis, R. Banerjea, C.R. Batchelor, P. Dark, K. Dudgeon, C.P. Green, E. Henderson, J. Ladocha, J. Weinstock, D.S. Young, J.-L. Schwenninger

“…Samples were also taken for optically stimulated luminescence dating (OSL) and accelerator mass spectrometry radiocarbon dating (AMS). …”
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A Dichotomy in the 1–24 GHz Parsec-scale Radio Spectra of Radio-quiet Quasars by Sina Chen, Ari Laor, Ehud Behar, Ranieri D. Baldi, Joseph D. Gelfand, Amy E. Kimball

“…The radio core emission generally exhibits a flat spectrum at 1.5–5.0 GHz, which indicates a compact optically thick synchrotron source on a scale smaller than the broad-line region (BLR) radius R _BLR  ∼ 0.01–0.1 pc. …”
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Recomendaciones para el diagnóstico y tratamiento de las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilo by Enrique Morales, Iñigo Rúa-Figueroa, José Luis Callejas Rubio, Ana Ávila Bernabéu, Ricardo Blanco Alonso, Maria C. Cid Xutgla, Gema Fernández Juárez, Natalia Mena-Vázquez, Juan José Ríos Blanco, Joaquín Manrique Escola, F. Javier Narváez García, Bernardo Sopeña, Luis F. Quintana Porras, Susana Romero-Yuste, Roser Solans Laqué

“…The use of glucocorticoids, cyclophosphamide and other immunosupressants (such as azathioprine, mychophenolate and methotrexate) was optimised in a series of clinical trials that established the treatment of reference. …”
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Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients by C Wheeler, C Masimirembwa, B Mthembu, J Botha, J Scholefield, J Fabian

“…Information from this study may inform the development of an Afrocentric tacrolimus precision-medicine algorithm to optimise recipient safety and graft outcomes. …”
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Recommendations for the diagnosis and treatment of anti-neutrophil cytoplasmic autoantibody associated vasculitis by Enrique Morales, Iñigo Rúa-Figueroa, José Luis Callejas Rubio, Ana Ávila Bernabéu, Ricardo Blanco Alonso, María C. Cid Xutgla, Gema Fernández Juárez, Natalia Mena-Vázquez, Juan José Ríos Blanco, Joaquín Manrique Escola, F. Javier Narváez García, Bernardo Sopeña, Luis F. Quintana Porras, Susana Romero-Yuste, Roser Solans Laqué

“…The use of glucocorticoids, cyclophosphamide and other immunosupressants (such as azathioprine, mychophenolate and methotrexate) was optimised in a series of clinical trials that established the treatment of reference. …”
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RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melan... by Sara Egea‐Rodriguez, Renáta Váraljai, Thierry M. Nordmann, Restuan Lubis, Manuel Philip, Florian Rambow, Alexander Roesch, Michael Flaig, Susanne Horn, Raphael Stoll, Fang Zhao, Annette Paschen, Bert Klebl, Ian D. Hickson, Dirk Schadendorf, Matthias Mann, Iris Helfrich

“…Conclusions Our findings unraveled the pivotal role of RECQL4 in immune modulation and its potential as both a predictive biomarker and therapeutic target for optimising immunotherapeutic strategies across various cancer types. …”
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Mycosynthesis of chitosan-selenium nanocomposite and its activity as an insecticide against the cotton leafworm Spodoptera littoralis by Sohila A. Ibrahiem, Fifi M. Reda, Eman M. Abd-ElAzeem, Mostafa S. Hashem, Hala A. Ammar

“…The biosynthesized nanomaterials were initially detected optically by the formation of a red color in the solution mixture and the appearance of a strong plasmon resonance peak at 240–300 nm. …”
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Preparation of Iron Oxide and Titania-Based Composite, Core-Shell Populated, Nanoparticulates Material by Two-Step LASER Ablation in Aqueous Media as Antimicrobial and Anticancer A... by Hasan H. Bahjat, Raid A. Ismail, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Mohsen Al-Omar, Salman A. A. Mohammed, Riaz A. Khan

“…The prepared monometallics, composite, and core-shell NPs structures were confirmed from the XRD, TEM, and EDX analyses, followed by the FE-SEM and UV absorptions. Optically, the NPs exhibited an increase in the energy gap from 3.27 eV to 3.75 eV as LASER fluence increased from 30 mJ/cm2 to 60 mJ/cm2. …”
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Effect of EOG Signal Filtering on the Removal of Ocular Artifacts and EEG-Based Brain-Computer Interface: A Comprehensive Study by Malik M. Naeem Mannan, M. Ahmad Kamran, Shinil Kang, Myung Yung Jeong

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Assainissement des eaux usées et risques socio – sanitaires et environnementaux en zones d’habitat planifié de Yaoundé (Cameroun) by Joseph Wethé, Michel Radoux, Emile Tanawa

“…La mise en œuvre de tels systèmes nécessite de maîtriser les paramètres socio-économiques, urbanistiques, sanitaires et environnement du contexte considéré. L'optimisation de l'efficacité épuratoire des stations extensives nécessite d'organiser et de structurer artificiellement les espèces aquatiques utilisées afin de maximiser la rétention des polluants présents dans les eaux usées. …”
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Nature and prevalence of long-term conditions in people with intellectual disability: retrospective longitudinal population-based study by Ashley Akbari, Navjot Kaur, Rania Kousovista, Gemma Lewin, Emeka Abakasanga, Rishika Shivamurthy, Georgina Cosma, Gyuchan Jun, Satheesh Gangadharan

“…Clusters of multiple long-term conditions, trajectories, outcomes and risk factors should be explored to optimise the understanding and longitudinal care of individuals with intellectual disabilities and long-term conditions.…”
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Emerging burden of post-cancer therapy complications on unplanned hospitalisation and costs among Australian cancer patients: a retrospective cohort study over 14 years by Rashidul Alam Mahumud, Md. Shahjalal, Padam Kanta Dahal, Md. Parvez Mosharaf, Sabuj Kanti Mistry, Kamrun Nahar Koly, Sujana Haque Chowdhury, Andre M. N. Renzaho, Jeff Gow, Khorshed Alam, Olivia Wawryk

“…The results highlight the need for better-customized treatment delivery strategies to address this burden and optimise resources in cancer care.…”
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