An exergy-based analysis for the synthesis of aromatics from biomass by Mohammed Usman, Joseph Akintola, Gabriel Umoh, Joseph Akpan, Ekpotu Wilson, Queen Moses, Philemon Udom, Edose Osagie

“…This study demonstrates the two process routes’ long-term economic viability and efficiency, which can be further optimised in future studies to achieve sustainable process implementation.…”
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Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy by Stewart D. Ramsay, Stewart D. Ramsay, Stewart D. Ramsay, Marni A. Nenke, Marni A. Nenke, Emily J. Meyer, Emily J. Meyer, David J. Torpy, David J. Torpy, Richard L. Young, Richard L. Young, Richard L. Young, Richard L. Young

“…Chronotherapy and chronopharmacotherapy are promising approaches to resynchronise circadian rhythms or leverage circadian rhythms to optimise medication efficacy, respectively, and hold much potential in the treatment of sepsis and septic shock. …”
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Does knowledge of sleep hygiene recommendations match behaviour in Australian shift workers? A cross-sectional study by Grace E Vincent, Sally A Ferguson, Caroline M Rampling, Charlotte Cecelia Gupta, Alexandra E Shriane, Gabrielle Rigney

“…Future research should focus on the development of sleep hygiene interventions that accommodate the unique challenges of shift work to optimise sleep.…”
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Tailoring lipid management interventions to reduce inequalities in cardiovascular disease risk management in primary care for deprived communities in Northern England: a mixed-meth... by Julia L Newton, Yu Fu, Sarah Sowden, Paula Whitty, Eugene YH Tang

“…This study describes the protocol for the development of a tailored intervention aiming to optimise lipid management in primary care settings to help reduce inequalities in CVD risks and improve outcomes in deprived communities.Methods and analysis A mixed-methods approach will be employed consisting of four work packages: (1) rapid review and logic model; (2) assessment and comparison of CVD risk management for deprived with non-deprived populations in Northern England to England overall; (3) interviews with health professionals; and (4) intervention development. …”
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Involvement of HLADQA1*05 in Patients with Inflammatory Bowel Disease Treated with Anti-TNF Drugs by Anna Pau, Ilaria Galliano, Elisa Barnini, Maddalena Dini, Antonio Pizzol, Alice Ponte, Stefano Gambarino, Pier Luigi Calvo, Massimiliano Bergallo

“…Testing for HLA-DQA105 can aid in personalising treatment and optimising therapy to minimise immunogenicity risks.…”
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Cataract surgery has minimal effect on corneal shape by Vito Romano, Stephen B Kaye, Keri McLean, Luca Pagano, Esmaeil M Arbabi, Fadi Alfaqawi, Ahmed Al-Maskari, Gabriella Czanner

“…Greater emphasis, however, should be placed on eye-specific factors, such as biometry, or patient-related factors to optimise refractive outcomes.…”
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Delirium and Cognitive Screening in National Hip Fracture Registries: Scoping Review Protocol [version 2; peer review: 2 approved] by Pamela Hickey, Rose S. Penfold, Louise Brent, Niamh A. Merriman, Eithne Sexton, Tara Coughlan, Mary E. Walsh, Antony Johansen, Catherine Blake, Alasdair M. J. MacLullich, Andrew J. Hall, Cristina Ojeda-Thies

“…Conclusion By identifying existing heterogeneity in delirium and cognitive screening tool use and administration, it is hoped that administration and specific screening tool use will become standardised to optimise comparability across countries and ensure that high quality and reliable data are included across international registry reports.…”
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Application of photogrammetry and laser scanner on the Bronze Age structures of the Castillejos de Luna cist tomb necropolis (Pizarra, Spain) by Alejandro Muñoz-Muñoz, Diego Fernández-Sánchez, Eduardo Vijande-Vila, Serafín Becerra-Martín, Juan Jesús Cantillo-Duarte, Salvador Domínguez-Bella, Virgilio Martínez Enamorado, Francisca Rengel Castro, Pedro Cantalejo Duarte, María del Mar Espejo-Herrerías, José Suárez-Padilla, Juan Antonio Martín-Ruiz, José Ramos-Muñoz

“…The preliminary results are published in the web repository of 3D models Sketchfab, where the users can see a preview of one of the tombs before and after being optimised with retopology through Blender. The authors provide a socio-historical analysis of Bronze Age necropolises in central Andalusia, within the framework of a debate on the western expansion of the El Argar Culture.…”
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Interpretation services used for non-English language speaking patients with head and neck cancer: Findings from a tertiary London cancer centre by Maesaya Chartkul, Florence Cook, Roganie Govender

“…Future research should investigate how this can be optimised to ensure necessary language support is provided consistent with guidelines that promote equality, diversity, and inclusion.…”
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Teamwork between registered nurses and unlicensed assistive personnel in acute care settings: A scoping review by Kang Lynn Wong, Wei Ling Chua, Peter Griffiths, Qin Ling Pearlyn Goh, Kye Wern Chelsea Low, Jia Qi Apphia Tan, Sok Ying Liaw

“…Future research should focus on optimising communication processes and enhancing registered nurses’ delegation skills through education.…”
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CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models by Maia Cabrera, Romina Armando, Ian Czarnowski, Patricio Chinestrad, Ramiro Blanco, Alejandra Zinni, Daniel Gómez, Diego L. Mengual Gómez, Pablo Lorenzano Menna

“…Future studies will focus on optimising these candidates and assessing their efficacy in vivo glioblastoma models, reassuring the thoroughness of our research and the potential for further advancements.…”
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Epidemiology, microbiology and clinical impacts of non-tuberculous mycobacteria in adult patients with cystic fibrosis by Zoltán Örlős, Lilla Katalin Lőrinczi, Balázs Antus, Imre Barta, Zsuzsanna Miklós, Ildikó Horváth

“…Detailed description of regional NTM prevalence and distribution, and identification of predictors of NTM acquisition in CF are essential to optimise treatment and surveillance guidelines. Methods: A retrospective, multi-center analysis was conducted between the years 2020 and 2022 on data from 232 adult patients registered in the Hungarian CF Registry in 2022. …”
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Comparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano by Biodun Bintu Adebakin, Mayor Orezime Atima, Ugbede Idakwo, Jamilu Abubakar Bala, Alhasan Sharif Abdullahi, Auwal Bello Muhammad, Jah Douglas Pam, Emeka John Dingwoke, Florence Olufunke Darda

“…Accurate diagnosis is essential to prevent retinal damage and optimise treatment. This study aimed to compare three diagnostic methods funduscopy, serology (ELISA), and PCR in detecting ocular toxoplasmosis in patients at ECWA Eye Hospital, Kano, Nigeria.Methods and analysis A total of 264 patients suspected of having ocular toxoplasmosis were enrolled. …”
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Acute Severe Anaphylaxis in Nepali Patients with Neurotoxic Snakebite Envenoming Treated with the VINS Polyvalent Antivenom by Sanjib Kumar Sharma, Emilie Alirol, Anup Ghimire, Suman Shrestha, Rupesh Jha, Surya B. Parajuli, Deekshya Shrestha, Surya Jyoti Shrestha, Amir Bista, David Warrell, Ulrich Kuch, Francois Chappuis, Walter Robert John Taylor

“…Severe ARA was common and recurrent and had overlapping signs with severe neurotoxic envenoming. Optimising the management of ARA at different healthy system levels needs more research. …”
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Lysine requirement of weaned piglets by S. Goethals, P. Bikker, J.H.M. Rijpert, B. Ampe, J.W. Spek, S. Millet

“…Variability in lysine requirements arises due to factors such as age, sex and environmental conditions. Optimising pig health and production efficiency and minimising nitrogen excretion require accurate knowledge of estimated lysine requirements accounting for factors such as genetics, feeding practices, scientific advancements, and environmental considerations. …”
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Heart rate cost as a tool for monitoring recovery between acute training sessions by José Morais Souto Filho, Milton Rocha de Moraes, Patrício Lopes de Araújo Leite, Larissa Alves Maciel, Andréa Cândida Arruda Andrade Rezende, Thiago dos Santos Rosa, Fabiana Andrade Machado, Sergio Rodrigues Moreira, Ricardo Yukio Assano, Marcelo Magalhães Sales, Herbert Gustavo Simões

“…Purpose Effective recovery monitoring is crucial to optimise performance and prevent overreaching, injuries, and overtraining. …”
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Adaptations to the welsh national exercise referral scheme during the COVID-19 pandemic: a qualitative study exploring the experiences of service users and providers and supplement... by Katie Newby, Neil Howlett, Adam P. Wagner, Nigel Lloyd, Imogen Freethy, Charis Bontoft, Olujoke Fakoya, Shelley Jackson, Carla Jackson, Wendy Wills, Mary-Ann McKibben, Annie Petherick, Katherine E. Brown

“…Findings provide wider evidence to inform adaptations that could be made to ensure that other exercise referral schemes can optimise virtual delivery.…”
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Solid-State Modification Strategies for Alpha-Mangostin Solubility Enhancement: A Review on Recent Progress by Nurin Syamimi Ahmad Izuren Shah, Muhammad Taher Bakhtiar, Syarifah Abd Rahim, Fatmawati Adam, Wan Hazman Danial, Mohd Rushdi Abu Bakar

“…These findings highlight the potential of solubility enhancement strategies to optimise AM’s pharmaceutical applications and provide a framework for improving the bioavailability of other poorly water-soluble compounds. …”
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Strained two-dimensional tungsten diselenide for mechanically tunable exciton transport by Jin Myung Kim, Kwang-Yong Jeong, Soyeong Kwon, Jae-Pil So, Michael Cai Wang, Peter Snapp, Hong-Gyu Park, SungWoo Nam

“…Wrinkle architecture enabled optically-resolvable local strain (2.4%) and energy gradient (49 meV/μm) to WSe2. …”
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Experience of being a frequent user of primary care and emergency department services: a qualitative systematic review and thematic synthesis by Catherine Hudon, Maud-Christine Chouinard, Magaly Brodeur, Eva Margo-Dermer

“…In the recent years, many jurisdictions have attempted to implement different public policies to optimise the use of health services by frequent users. …”
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