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    Evaluation of Clinical Interest of Anti-Aquaporin-4 Autoantibody Followup in Neuromyelitis Optica by Jean-Baptiste Chanson, Melissa Alame, Nicolas Collongues, Frédéric Blanc, Marie Fleury, Gabrielle Rudolf, Jérôme de Seze, Thierry Vincent

    Published 2013-01-01
    “…Neuromyelitis optica (NMO) is an autoimmune disease in which a specific biomarker named NMO-IgG and directed against aquaporin-4 (AQP4) has been found. …”
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  3. 503

    The Big Yawning: Pathological Yawning as a Symptom of Neuromyelitis Optica Spectrum Disorders by Veronika Spahlinger, Annette Niessen, Sebastian Rauer, Stefan Krämer, Matthias Reinhard

    Published 2019-01-01
    “…MRI showed a cervical myelitis over more than three vertebral segments up to the lower medulla and Aquaporin-4-antibodies were positive (diagnostic criteria for a Neuromyelitis optica spectrum disorder were fulfilled). Under treatment with methylprednisolone, followed by plasmapheresis and immunoadsorption, clinical symptoms were regressive and the frequency of yawning completely normalized. …”
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  4. 504

    Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering by Ryohei Yamamura, Makoto Kinoshita, Yoshiaki Yasumizu, Yoshiaki Yasumizu, Yoshiaki Yasumizu, Tomohiro Yata, Keigo Kihara, Daisuke Motooka, Daisuke Motooka, Naoyuki Shiraishi, Yasuko Sugiyama, Shohei Beppu, Hisashi Murata, Naoshi Koizumi, Itsuki Sano, Toru Koda, Tatsusada Okuno, Hideki Mochizuki

    Published 2025-02-01
    “…BackgroundThe advent of biologics has significantly transformed treatment strategies for neuromyelitis optica spectrum disorder (NMOSD). However, there are no biomarkers that predict relapses associated with steroid tapering; therefore, it is critical to identify potential indicators of disease activity. …”
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    Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation by Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin Rittinger

    Published 2025-01-01
    “…Here we present a chemoproteomics fragment screening platform for identifying novel DUB-specific hit matter, that combines activity-based protein profiling with high-throughput chemistry direct-to-biology optimisation to enable rapid elaboration of initial fragment hits against OTU DUBs. …”
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  10. 510

    Comparison of Kolmogorov–Arnold Networks and Multi-Layer Perceptron for modelling and optimisation analysis of energy systems by Talha Ansar, Waqar Muhammad Ashraf

    Published 2025-05-01
    “…It is anticipated that the scientific, research and industrial community may benefit from the fundamental insights presented in this paper for the ML algorithm selection and carrying out model-based optimisation analysis for the performance enhancement of energy systems.…”
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    Improved TLBO-JAYA Algorithm for Subset Feature Selection and Parameter Optimisation in Intrusion Detection System by Mohammad Aljanabi, Mohd Arfian Ismail, Vitaly Mezhuyev

    Published 2020-01-01
    “…Many optimisation-based intrusion detection algorithms have been developed and are widely used for intrusion identification. …”
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  14. 514

    Optimisation of Water-Use in Pulp and Paper Mills: A Streamlined Review of Scientific Journal Publications by Felicia Ocklind, Kristin Liback, Lova Lundqvist, Wilma Harge, G Venkatesh

    Published 2024-08-01
    “…Besides, there is also a nexus between water and energy here, with optimisation of the use of one of these resoruces enabling that of the other too. …”
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    Optimising the mechanism of electroshock treatment on the tensile behaviour of the laser melting deposited Ti55531 alloy by Chang Liu, Haoxing Wang, Jian Zhou, Yan Wen, Lechun Xie, Liqiang Wang, Lin Hua

    Published 2025-12-01
    “…All results indicate that EST is an effective and novel way to optimising the tensile properties of LMD titanium alloys.…”
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    Optimisation of the Monitoring Strategy of Macroinvertebrate Communities in the River Dender, in Relation to the EU Water Framework Directive by Tom P. D’heygere, Peter L.M. Goethals, Niels De Pauw

    Published 2002-01-01
    “…There are also seasonal differences between the macroinvertebrate communities when the Dender and its tributaries are examined separately. An optimised monitoring strategy is proposed based on these results and the EU Water Framework Directive. …”
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