-
2181
A Case of Relapsing Polychondritis Initiating with Unexplained Fever
Published 2016-01-01Get full text
Article -
2182
Distance Learning For Military Doctors in Crisis Situations: The DILEMMA Cross-Sectional Study Results
Published 2024-01-01“…Primary and secondary endpoints were analyzed for groups of interns (DILEMMA-1, n=78) and physicians with practical experience participating in postgraduate activities at UMMA (DILEMMA-2, n=69). …”
Get full text
Article -
2183
Impact of clinical pharmacist integration on diabetes management: a prospective cohort
Published 2025-01-01Get full text
Article -
2184
La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine
Published 2020-12-01“…It rains on average one day out of two. This explains the importance of the network of water evacuation, which was one of the main problems faced by the inhabitants of Bibracte. …”
Get full text
Article -
2185
Design and validation of value-oriented strategic marketing model in Iranian airlines
Published 2025-03-01Get full text
Article -
2186
-
2187
A Case of Skull Base Osteomyelitis with Multiple Cerebral Infarction
Published 2016-01-01Get full text
Article -
2188
-
2189
Older Adults Accessing HIV Care and Treatment and Adherence in the IeDEA Central Africa Cohort
Published 2012-01-01Get full text
Article -
2190
-
2191
Congenital vitamin D deficiency: presenting with feeding difficulty in early infancy: a case report
Published 2025-02-01Get full text
Article -
2192
Clinical outcomes following shock team implementation for cardiogenic shock: a systematic review
Published 2024-12-01Get full text
Article -
2193
Variability of Ionosphere Over Indian Longitudes to a Variety of Space Weather Events During December 2006
Published 2023-11-01Get full text
Article -
2194
-
2195
Effects of Kalsis, A Dietary Supplement, on Bone Metabolism in the Ovariectomized Rats
Published 2012-01-01Get full text
Article -
2196
Estimation of Radiological Effects from Consumption of milk from Volcanic areas of Kisoro, South-western Uganda.
Published 2023“…The average activity concentrations in milk for U-238, Th-232, and K-40 were; 1.058 Bq l-1, 1.369 Bq l-1, and 19.679 Bq l-1 ,respectively. …”
Get full text
Article -
2197
Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer: a prospective cohort study
Published 2025-02-01“…Four risk factors were identified as key predictors of PICC-RVT, including “diabetes requiring insulin (OR: 8.016; 95% CI 1.157–55.536), major surgery (within 1 month and operation time > 45 minutes) (OR: 0.023; 95% CI 1.296–30.77), reduced limb activities of the PICC arm (OR: 6.687; 95% CI 2.024–22.09)” and “catheter material (OR: 3.319; 95% CI 0.940–11.723)”. …”
Get full text
Article -
2198
Timeliness metrics for screening and preventing TB in household contacts of pulmonary TB patients in Kenya
Published 2024-01-01Get full text
Article -
2199
UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research
Published 2025-01-01“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
Get full text
Article -
2200