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  1. 1681

    Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial by Xiaomei Li, Xiaoxia Wang, Jian Wu, Xiao Zhang, Chunde Bao, Shengqian Xu, Lingyun Sun, Juan Wang, Guixiu Shi, Xiaofei Wang, Qing Dai, Antao Xu, Huaxiang Wu, YongQing Wang, Yan Ye, Yongfu Wang, Huaxiang Liu, Chenyin Lv, Jun Miao, Weiqi Min, Kuanting Wang, Luan Xue, Shanhui Ye

    Published 2025-01-01
    “…Objective The objective of this study is to evaluate the efficacy and safety of jaktinib hydrochloride tablets (jaktinib), a Janus kinase inhibitor, in patients with active radiographic axial spondyloarthritis (r-axSpA).Methods Adults with active r-axSpA who met modified New York criteria and had an inadequate response to non-steroidal anti-inflammatory drugs were randomised 1:1:1 to receive jaktinib 75 mg two times per day, 100 mg two times per day, or placebo. …”
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  2. 1682

    Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab... by Yongwei Huang, Zongping Li, Jianjun Wang, Jianjun Wang, Decai Wang, Decai Wang, Xiaoshuang Yin

    Published 2025-01-01
    “…After fully adjustment, MCR models indicated a heightened mortality risk for the ICU (hazard ratio [HR] = 1.55, 95% confidence interval [CI]: 1.08–2.22; p = 0.02), 30-day (HR = 1.87, 95% CI: 1.46–2.38; p < 0.001), 90-day (HR = 1.75, 95% CI: 1.42–2.15; p < 0.001), and 365-day (HR = 1.81, 95% CI: 1.50–2.19; p < 0.001) in the high BAR group as opposed to the low BAR group. …”
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  3. 1683

    Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows by Nicola Oosthuizen, Lucas M. Goncalves, Samir Burato, Molly S. Smith, Kelsey M. Harvey, Graham Cliff Lamb, Graham Cliff Lamb, Pedro L. P. Fontes

    Published 2025-02-01
    “…Within each location, cows were randomly assigned to one of four treatments: (1 and 2) cows were estrus synchronized using the 7-day CO-Synch + CIDR protocol (7D) wherein they received an injection of one of two GnRH compounds [gonadorelin hydrochloride (GH) or gonadorelin diacetate tetrahydrate (GDT)] and a controlled internal drug release (CIDR) device on day 0, an injection of prostaglandin F2α (PG) at CIDR removal on day 7, and a second injection of their respective GnRH compound at fixed-time artificial insemination (TAI) on day 10 (7D-GH and 7D-GHT); (3 and 4) cows were treated with the 7&7 Synch (7&7) protocol, wherein they were treated the same as treatments 1 and 2 but received their CIDR inserts on day -7 in conjunction with an injection of PG (7&7-GH and 7&7-GDT). …”
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  4. 1684

    Antibacterial action of penicillin against Mycobacterium avium complex by D. Deshpande, G. Magombedze, S. Srivastava, T. Gumbo

    Published 2024-08-01
    “…RESULTS: Benzylpenicillin killed >2.1 log 10 colony-forming unit (CFU)/mL below Day 0, better than azithromycin, ethambutol, and rifabutin. …”
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    Associations between sedentary behaviour and sarcopenia among patients aged 40 and older with chronic obstructive pulmonary disease: a cross-sectional study by Dandan Wang, Ming Zhang, Jun Huang, Haihong Zhang, Si Chen, Kefang Wang

    Published 2025-01-01
    “…SB was categorized into 4 categories: less than 4 h/day, 4 to 6 h/day, 6 to 8 h/day, and 8 h or more per day. …”
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  8. 1688
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  10. 1690

    Islamic Stocks and Russia – Ukraine War: Evidence from the Jakarta Islamic Index by Erna Listyaningsih, Amirul Mukminin, Lenny Marzulina, Kasinyo Harto, Muhammad Rachmad, Muazza Muazza

    Published 2024-04-01
    “… Previous research revealed that non-economic variables affected stock returns. War is one of the non-economic factors. All international stock markets were under pressure because of the conflict between Russia and Ukraine. …”
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  11. 1691

    Co-authorship networks: Collaborative research structures at the journal level by José António C. Santos, Margarida Custódio Santos

    Published 2016-01-01
    “…Present-day research is, in most cases, the outcome of collaborative research, as evidenced by the fact that most papers are authored by two or more researchers. …”
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  12. 1692
  13. 1693

    cfDNA as a surrogate marker for COVID-19 severity in patients with influenza-like symptoms with and without SARS-CoV-2 infections in general practice: a study protocol for a prospe... by Dorothea Dehnen, Elmo Neuberger, Jürgen in der Schmitten, Ekaterini Giagkou, Perikles Simon, Suzan Botzenhardt

    Published 2022-06-01
    “…The primary objective is to compare cfDNA levels in ambulatory patients in general practice with flu-like symptoms with SARS-CoV-2 infection with those with influenza like symptoms without a SARS-CoV-2 infection during the disease (day 7 and day 14). The secondary objective is to determine whether there is a correlation between cfDNA concentrations on the one hand, and laboratory and clinical parameters on the other hand. cfDNA, differential blood count, high-sensitive CRP and erythrocyte sedimentation rate will be measured in blood samples, concomitant symptoms will be surveyed via a self-assessment questionnaire, and oxygen saturation, breathing rate and examination of the lungs will be reported by treating physicians.Ethics and dissemination Ethical approval was issued on 1 March 2021 by the Ethics Committee Essen under the number 21-9916-BO. …”
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  17. 1697

    Impact of thrombocytopenia on failure of endoscopic variceal treatment in cirrhotic patients with acute variceal bleeding by Yan He, Fernando Gomes Romeiro, Mingyu Sun, Fanpu Ji, Qiang Zhu, Yingli He, Dapeng Ma, Shanshan Yuan, Xiaofeng Liu, Cyriac Abby Philips, Metin Basaranoglu, Nahum Méndez-Sánchez, Kanokwan Pinyopornpanish, Yiling Li, Yunhai Wu, Ling Yang, Lichun Shao, Andrea Mancuso, Yu Chen, Frank Tacke, Su Lin, Lei Liu, Bimin Li, Xingshun Qi

    Published 2025-01-01
    “…Thrombocytopenia was defined as platelet count below 150 × 10 9 /L and further classified as mild (100 × 10 9 /L–150 × 10 9 /L), moderate (50 × 10 9 /L–100 × 10 9 /L), and severe (<50 × 10 9 /L). A 1:1 propensity score matching (PSM) analysis was performed. …”
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