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Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial
Published 2025-01-01“…Objective The objective of this study is to evaluate the efficacy and safety of jaktinib hydrochloride tablets (jaktinib), a Janus kinase inhibitor, in patients with active radiographic axial spondyloarthritis (r-axSpA).Methods Adults with active r-axSpA who met modified New York criteria and had an inadequate response to non-steroidal anti-inflammatory drugs were randomised 1:1:1 to receive jaktinib 75 mg two times per day, 100 mg two times per day, or placebo. …”
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1682
Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab...
Published 2025-01-01“…After fully adjustment, MCR models indicated a heightened mortality risk for the ICU (hazard ratio [HR] = 1.55, 95% confidence interval [CI]: 1.08–2.22; p = 0.02), 30-day (HR = 1.87, 95% CI: 1.46–2.38; p < 0.001), 90-day (HR = 1.75, 95% CI: 1.42–2.15; p < 0.001), and 365-day (HR = 1.81, 95% CI: 1.50–2.19; p < 0.001) in the high BAR group as opposed to the low BAR group. …”
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1683
Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows
Published 2025-02-01“…Within each location, cows were randomly assigned to one of four treatments: (1 and 2) cows were estrus synchronized using the 7-day CO-Synch + CIDR protocol (7D) wherein they received an injection of one of two GnRH compounds [gonadorelin hydrochloride (GH) or gonadorelin diacetate tetrahydrate (GDT)] and a controlled internal drug release (CIDR) device on day 0, an injection of prostaglandin F2α (PG) at CIDR removal on day 7, and a second injection of their respective GnRH compound at fixed-time artificial insemination (TAI) on day 10 (7D-GH and 7D-GHT); (3 and 4) cows were treated with the 7&7 Synch (7&7) protocol, wherein they were treated the same as treatments 1 and 2 but received their CIDR inserts on day -7 in conjunction with an injection of PG (7&7-GH and 7&7-GDT). …”
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1684
Antibacterial action of penicillin against Mycobacterium avium complex
Published 2024-08-01“…RESULTS: Benzylpenicillin killed >2.1 log 10 colony-forming unit (CFU)/mL below Day 0, better than azithromycin, ethambutol, and rifabutin. …”
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1686
Efficacy Of Triamcinolone Injection In Management Of Oral Lichen Planus
Published 2024-03-01Get full text
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1687
Associations between sedentary behaviour and sarcopenia among patients aged 40 and older with chronic obstructive pulmonary disease: a cross-sectional study
Published 2025-01-01“…SB was categorized into 4 categories: less than 4 h/day, 4 to 6 h/day, 6 to 8 h/day, and 8 h or more per day. …”
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1688
Beverage Intake and Its Effect on Body Weight Status among WIC Preschool-Age Children
Published 2019-01-01Get full text
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1689
Urban and rural residence: their influence on food group consumption in Iran
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1690
Islamic Stocks and Russia – Ukraine War: Evidence from the Jakarta Islamic Index
Published 2024-04-01“… Previous research revealed that non-economic variables affected stock returns. War is one of the non-economic factors. All international stock markets were under pressure because of the conflict between Russia and Ukraine. …”
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Co-authorship networks: Collaborative research structures at the journal level
Published 2016-01-01“…Present-day research is, in most cases, the outcome of collaborative research, as evidenced by the fact that most papers are authored by two or more researchers. …”
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1693
cfDNA as a surrogate marker for COVID-19 severity in patients with influenza-like symptoms with and without SARS-CoV-2 infections in general practice: a study protocol for a prospe...
Published 2022-06-01“…The primary objective is to compare cfDNA levels in ambulatory patients in general practice with flu-like symptoms with SARS-CoV-2 infection with those with influenza like symptoms without a SARS-CoV-2 infection during the disease (day 7 and day 14). The secondary objective is to determine whether there is a correlation between cfDNA concentrations on the one hand, and laboratory and clinical parameters on the other hand. cfDNA, differential blood count, high-sensitive CRP and erythrocyte sedimentation rate will be measured in blood samples, concomitant symptoms will be surveyed via a self-assessment questionnaire, and oxygen saturation, breathing rate and examination of the lungs will be reported by treating physicians.Ethics and dissemination Ethical approval was issued on 1 March 2021 by the Ethics Committee Essen under the number 21-9916-BO. …”
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An animal model of severe acute respiratory distress syndrome for translational research
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1697
Impact of thrombocytopenia on failure of endoscopic variceal treatment in cirrhotic patients with acute variceal bleeding
Published 2025-01-01“…Thrombocytopenia was defined as platelet count below 150 × 10 9 /L and further classified as mild (100 × 10 9 /L–150 × 10 9 /L), moderate (50 × 10 9 /L–100 × 10 9 /L), and severe (<50 × 10 9 /L). A 1:1 propensity score matching (PSM) analysis was performed. …”
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Intestinal Obstruction in a Child with Massive Ascariasis
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