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Distance Learning For Military Doctors in Crisis Situations: The DILEMMA Cross-Sectional Study Results
Published 2024-01-01“…Primary and secondary endpoints were analyzed for groups of interns (DILEMMA-1, n=78) and physicians with practical experience participating in postgraduate activities at UMMA (DILEMMA-2, n=69). …”
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Impact of clinical pharmacist integration on diabetes management: a prospective cohort
Published 2025-01-01Get full text
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2343
La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine
Published 2020-12-01“…It rains on average one day out of two. This explains the importance of the network of water evacuation, which was one of the main problems faced by the inhabitants of Bibracte. …”
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Data-driven evaluation of background radiation safety using machine learning and statistical analysis
Published 2024-06-01Get full text
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A Case of Skull Base Osteomyelitis with Multiple Cerebral Infarction
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Congenital vitamin D deficiency: presenting with feeding difficulty in early infancy: a case report
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Clinical outcomes following shock team implementation for cardiogenic shock: a systematic review
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2350
Effects of Kalsis, A Dietary Supplement, on Bone Metabolism in the Ovariectomized Rats
Published 2012-01-01Get full text
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Possible Potentiation by Certain Antioxidants of the Anti-Inflammatory Effects of Diclofenac in Rats
Published 2014-01-01Get full text
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Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer: a prospective cohort study
Published 2025-02-01“…Four risk factors were identified as key predictors of PICC-RVT, including “diabetes requiring insulin (OR: 8.016; 95% CI 1.157–55.536), major surgery (within 1 month and operation time > 45 minutes) (OR: 0.023; 95% CI 1.296–30.77), reduced limb activities of the PICC arm (OR: 6.687; 95% CI 2.024–22.09)” and “catheter material (OR: 3.319; 95% CI 0.940–11.723)”. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research
Published 2025-01-01“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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Methods and Models of Market Risk Stress-Testing of the Portfolio of Financial Instruments
Published 2015-08-01Get full text
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DIPLOMATIC SUPPORT OF US INVOLVMENT IN THE KOREAN WAR JUNE 25 – JULY 6 1950: CRISIS RESPONSE EXPERIENCE
Published 2018-09-01Get full text
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Gradenigo’s Syndrome and Bacterial Meningitis in a Patient with a Petrous Apex Cholesterol Granuloma
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Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
Published 2022-01-01“…The approach was found to have intra- and inter-day precision values ranging from 1.42% to 6.91% and from 1.25% to 3.68%, respectively. …”
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