Restrictive transfusion strategy for critically injured patients (RESTRIC) trial: a study protocol for a cluster-randomised, crossover non-inferiority trial by Kaori Ito, Kazuhiko Sekine, Hiroaki Iijima, Yutaka Kondo, Takashi Tagami, Mineji Hayakawa, Daisuke Kudo, Takayuki Ogura, Tetsuya Yumoto, Akira Endo, Yosuke Matsumura, Shigeki Kushimoto

“…The outcomes measured will include the 28-day survival rate after arrival at the emergency department (primary), the cumulative amount of blood transfused, event-free days and frequency of transfusion-associated lung injury and organ failure (secondary). …”
Get full text

Sclerema Neonatorum in a Term Infant: A Case Report and Literature Review by Gloria Nakalema, Walufu Ivan Egesa, Patrick Kumbowi Kumbakulu, Martin Nduwimana, Amnia Diaz Anaya, Mirembe Stephen Kizito, Daniel Kavuma

Get full text

Solitary Nitric Oxide Signaling Mediates Mild Stress-Induced Anxiety and Norepinephrine Release in the Bed Nucleus of the Stria Terminalis during Protracted Ethanol Withdrawal by Zhenglin Zhao, Sang Chan Kim, Yu Jiao, Yefu Wang, Bong Hyo Lee, Hee Young Kim, Chul Won Lee, Chae Ha Yang, Rongjie Zhao

“…Rats were intraperitoneally administered 3 g/kg/day EtOH for 21 days followed by 28 days of withdrawal, and on the 28th day of withdrawal, the rats were subjected to restraint stress for 7 minutes. …”
Get full text

Association between screen time, including that for smartphones, and overweight/obesity among children in Japan: NICE EVIDENCE Study 4 by Izumi Ikeda, Kazuya Fujihara, Sakiko Morikawa Yoshizawa, Yasunaga Takeda, Hajime Ishiguro, Mayuko Yamada Harada, Chika Horikawa, Yasuhiro Matsubayashi, Takaho Yamada, Yohei Ogawa, Hirohito Sone

“…A cross-sectional study was conducted in 2,242 Japanese children (1,278 girls) aged 10–14 years. Overweight/obesity was defined by the International Obesity Task Force. …”
Get full text

Protocol for the generation of HLF+ HOXA+ human hematopoietic progenitor cells from pluripotent stem cells by Sherry Li Zheng, Jonas L. Fowler, Julie Y. Chen, Christopher Li, Elaine Lin, Alana T. Nguyen, Angela Chen, George Q. Daley, Lay Teng Ang, Kyle M. Loh

Get full text

Effect of comprehensive nursing interventions on relieving postoperative pain of breast cancer patients (乳腺肿瘤患者术后疼痛的护理干预研究) by LI Weijia (李唯佳), LI Yueru (李月茹), LI Ning (李宁), CAO Hongjing (曹红京)

Get full text

PROcalcitonin and NEWS2 evaluation for Timely identification of sepsis and Optimal use of antibiotics in the emergency department (PRONTO): protocol for a multicentre, open-label,... by David Taylor-Robinson, Steve Goodacre, Neil French, Richard Body, Kerenza Hood, Emma Thomas-Jones, Jane Daniels, Sarah Walker, Ingeborg Welters, Mike Bradburn, Paul Schmidt, Enitan Carrol, Lucy Brookes-Howell, Sarah Milosevic, Andrew Tabner, Philip Pallmann, Stephen Aston, Gavin Barlow, Emma Richards, Emmanuel Nsutebu, Philip Howard, Matthew Inada-Kim, Stacy Todd, Fiona McGill, Martin Llewelyn, Louis Wihelmus Niessen, Joanne Euden, Julie Carman, Stephanie Gilbert, Sam Clarkstone, Jacqui Hughes, Lena Meister, Angela Brain, Matthew Scarborough, Sian O'Shea, Claire James

“…PRONTO has two coprimary endpoints: initiation of intravenous antibiotics at 3 hours (superiority comparison) and 28-day mortality (non-inferiority comparison). The study has an internal pilot phase and group-sequential stopping rules for effectiveness and futility/safety, as well as a qualitative substudy and a health economic evaluation.Ethics and dissemination The trial protocol was approved by the Health Research Authority (HRA) and NHS Research Ethics Committee (Wales REC 2, reference 20/WA/0058). …”
Get full text

Newspaper “Rech” in the July Crisis of 1914 by B. S. Kotov

“…"Rech", founded in 1906 by the Constitutional Democratic Party (Kadets), was on the eve of the First World War one of the most important liberal organs of the Russian press. …”
Get full text

Microclimate monitoring in commercial tomato (Solanum Lycopersicum L.) greenhouse production and its effect on plant growth, yield and fruit quality by Jakub Šalagovič, Dorien Vanhees, Pieter Verboven, Kristof Holsteens, Bert Verlinden, Marlies Huysmans, Bram Van de Poel, Bram Van de Poel, Bart Nicolaï, Bart Nicolaï, Bart Nicolaï

“…Large greenhouses typically rely only on one central weather station per compartment to steer their internal climate, ignoring possible microclimate conditions within the greenhouse itself.MethodsIn this study, we analysed spatial variation in temperature and vapour pressure deficit in a commercial tomato greenhouse setting for three consecutive years. …”
Get full text

A Longer Duration of Intravenous Antibiotic Treatment for Patients with Early Periprosthetic Joint Infections Is Not Associated with a Lower Failure Rate by Janneke Meijer, Alex Soriano, Wierd Zijlstra, Bas ten Have, Saad Tarabichi, Paul Jutte, Javad Parvizi, Marjan Wouthuyzen-Bakker

Get full text

Ilaser Submucous Destruction in the Treatment of Hemorrhoids by S. A. Frolov, D. V. Vyshegorodtsev, A. M. Kuzminov, Yu. L. Trubacheva, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. N. Ryndin, A. A. Anarbaeva

Get full text

Presentation of knowledge sharing model in Bank Maskan Iran by Maryam Firoozi, ahmad vedadi, alireza Amirkabiri

“…In the current age, which is called the age of knowledge, organizations are witnessing environments that are becoming more dynamic and challenging day by day, and consider intangible and spiritual capital, called knowledge, as an important and vital factor (Firouzi & Feyzi, 2017). …”
Get full text

Assessing the physical activity training needs and preferences of community health workers in South Africa by Mark Stoutenberg, Blanca S. Noriega Esquives, Ruth G. St Fleur, Susanna S. Koen, Estelle D. Watson, Francia G. Portacio, Georgia Torres

“…Methods Community health promoters (CHPs), a type of CHWs in South Africa, from seven health districts in Johannesburg participated in a day-long in-service training on PA and healthy eating. …”
Get full text

Under simulated microgravity and gravity, anthocyanin is regulated by DcaWRKY2 in Dendrobium catenatum leaves by Tianze Hou, Baoqiang Zheng, Fucheng Peng, Zehui Jiang, Wenbo Zhang, Yan Wang

Get full text

Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance by Burak Korkmaz, Erhan Demirel, Qiang Ye, Qiang Ye, Anil Misra, Anil Misra, Candan Tamerler, Candan Tamerler, Candan Tamerler, Paulette Spencer, Paulette Spencer, Paulette Spencer

Get full text

African theological education and its curriculum responsiveness towards African Union’s Agenda 2063. by M. Naidoo

Get full text

Development and validation of a prognostic model for critically ill type 2 diabetes patients in ICU based on composite inflammatory indicators by Lin Liu, Yan-Bo Zhao, Zhuo-Ting Cheng, Ya-Hui Li, Yang Liu

“…Logistic and Cox regression analyses were used to evaluate the relationship between nine inflammatory indicators and ICU, 30-day, and 90-day mortality rates. Significant predictive variables were chosen using least absolute shrinkage selection operator (LASSO) regression from logistic regression results, and a prognostic prediction model was built with multivariate logistic regression. …”
Get full text

Risen Alive: The Lazarus Phenomenon by Waqar Haider Gaba, Shahad Abobakar El Hag, Shaima Mustafa Bashir

Get full text

Klebsiella pneumoniae Renal Abscess Syndrome: A Rare Case with Metastatic Involvement of Lungs, Eye, and Brain by Divyanshu Dubey, Fayez S. Raza, Anshudha Sawhney, Ambarish Pandey

Get full text

Efficacy and safety of SHEN26, a novel oral small molecular RdRp inhibitor for COVID-19 treatment: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical... by Jiangtao Bai, Tetsuya Asakawa, Wenfang Yuan, Yuanlong Lin, Hao Ju, Dandan Xu, Mingming Yang, Shuo Li, Guanguan Li, Deyin Guo, Hongzhou Lu, Xumu Zhang

Get full text