Inverse Agonist of Retinoid-Related Orphan Receptor-Alpha Prevents Apoptosis and Degeneration in Nucleus Pulposus Cells via Upregulation of YAP by Tongzhou Liang, Jincheng Qiu, Shaoguang Li, Zhihuai Deng, Xianjian Qiu, Wenjun Hu, Pengfei Li, Taiqiu Chen, Zhancheng Liang, Hang Zhou, Bo Gao, Dongsheng Huang, Anjing Liang, Wenjie Gao

“…In this study, we found that RORα, a member of the retinoid-related orphan receptor family, is significantly elevated in nucleus pulposus tissue in IDD patients. …”
Get full text

Undernutrition and Associated Factors among Under-Five Orphan Children in Addis Ababa, Ethiopia, 2020: A Cross-Sectional Study by Selam Shegaw Sewnet, Hunegnaw Almaw Derseh, Hanna Demelash Desyibelew, Netsanet Fentahun

“…However, there is little information about the prevalence of undernutrition and associated factors among under-five orphan children. Objective. This study aimed to assess undernutrition and associated factors among under-five orphan children in orphanages in Addis Ababa, Ethiopia. …”
Get full text

Orphan nuclear receptor NR2E3 is a new molecular vulnerability in solid tumors by activating p53 by Yidan Wang, Todd G. Kroll, Linhui Hao, Zhi Wen

“…Abstract The orphan nuclear receptor NR2E3 has emerged as a potential tumor suppressor, yet its precise mechanisms in tumorigenesis require further investigation. …”
Get full text

Similarities and Differences in the Glycosylation Mechanisms in Prokaryotes and Eukaryotes by Anne Dell, Alaa Galadari, Federico Sastre, Paul Hitchen

“…Like in eukaryotes, stepwise O-glycosylation occurs on diverse bacterial proteins including flagellins, adhesins, autotransporters and lipoproteins, with O-glycosylation chain extension often coupled with secretory mechanisms.…”
Get full text

Research on the Mechanism of Cold Chain Logistics Subsidy by Nai-Ru Xu, Zheng-Qun Cai

“…It is designed that a supply chain system consisting of duopoly upstream agro-products suppliers and a downstream agro-products retailer for research. The mechanism of cold chain logistics subsidy is studied by analyzing the influence of cold chain subsidy on pricing behavior and cold chain decision-making of cold chain agro-products and ordinary agro-products. …”
Get full text

Mechanism of Strain Burst by Laboratory and Numerical Analysis by Manchao He, Fuqiang Ren, Cheng Cheng

“…In order to further studying the mechanism of strain burst considering the whole system, the engineering geomechanial model and numerical model of strain burst due to excavation are built, respectively. …”
Get full text

Mechanical Properties and Nondestructive Testing of Advanced Materials by Yan Yang, Xing Chen, Young Soo Choi

Get full text

Virological Mechanisms in the Coinfection between HIV and HCV by Maria Carla Liberto, Emilia Zicca, Grazia Pavia, Angela Quirino, Nadia Marascio, Carlo Torti, Alfredo Focà

“…These effects are mediated by immune mechanisms and by a cross-talk between the two viruses which could interfere with host defense mechanisms. …”
Get full text

The interface between metallurgy and mechanics in material performance by M. N. James, M. Newby

“…The paper focuses on the problems associated with cracking and uses case study examples drawn from engineering practice to illustrate the role of metallurgical factors in mechanical performance of materials.…”
Get full text

Continuous Canopy Shake Mechanical Harvesting Systems by Stephen H. Futch, Fritz M. Roka

“… Mechanical harvesting systems harvested more than 17,000 acres of Florida citrus in the 2002-03 season. …”
Get full text

MECHANISMS AND CLINICAL PERSPECTIVES OF ALLERGEN-SPECIFIC IMMUNOTHERAPY by Leila Akhvlediani, Marina Izmailovich, Meruyert Gazaliyeva, Anna Skvortsova, Kanan Tanriverdiev

“…Results and Discussion: ASIT promotes immunological tolerance through mechanisms such as suppression of Th2 activity, increased IgG4 production, and reduced effector cell activation. …”
Get full text

Benefits of an Abscission Agent in Mechanical Harvesting of Citrus by Fritz Roka, Jackie Burns, Jim Syvertsen, Robert Ebel

“…FE752, a 4-page fact sheet by Fritz Roka, Jackie Burns, Jim Syvertsen, and Robert Ebel, describes research into the use of abscission agents in mechanical harvesting, to extend the harvesting window to later in the season, permit faster harvesting speed, enhance fruit recovery percentages, and reduce tree damage. …”
Get full text

Fluid-Structure Interaction Mechanisms for Close-In Explosions by Andrew B. Wardlaw Jr., J. Alan Luton

“…Computational examples of several close-in interaction cases are presented to document the occurrence of these mechanisms. By comparing deformable and rigid body simulations, it is shown that cavitation collapse can occur solely from the shock-bubble interaction without the benefit of target deformation. …”
Get full text

Regulatory mechanisms tuning ethylen signaling in plants by E. V. Zemlyanskaya, N. A. Omelyanchuk, A. A. Ermakov, V. V. Mironova

“…That is why understanding molecular mechanisms underlying ethylene action is one of the basic questions in plant biology that is addressed in the context of both fundamental research and application in agriculture. …”
Get full text

Data traceability mechanism based on consortium chain by Shoucai ZHAO, Lifeng CAO, Xuehui DU

“…With the unprecedented growth in the speed of data generation and circulation in the era of big data, the emergence of blockchain technology provides a new solution for data authenticity verification.However, with the increasing demand for data flow between different blockchains, new security issues arise.Cross-chain data transmission can lead to data leakage, and detecting data leakage caused by illegal access becomes challenging.To address these problems, a data traceability mechanism based on a consortium chain was proposed.A cross-blockchain data traceability model was designed, incorporating private data pipelines to ensure the security of cross-chain data transmission.User behaviors were recorded through authorization and access logs, ensuring the traceability of illegal unauthorized access.To improve the efficiency of data traceability and query, an on-chain and off-chain synchronous storage mechanism was adopted.The state of data flow before each transaction was encrypted and stored in the database, and its index was stored in the blockchain transaction.This enables a one-to-one correspondence between on-chain and off-chain data.Additionally, Merkle trees were introduced into the block body to store block summaries, enhancing the efficiency of block legitimacy verification.Based on the data storage form and cross-chain data interaction mechanism, a data traceability algorithm was designed.The traceability results were displayed in the form of an ordered tree.An experimental environment for consortium chain traceability was built using fabric, targeting the cross-domain data traceability scenario in the e-commerce industry.The GO language was used to simulate and test the data traceability performance with a large number of blocks and transactions.The results demonstrate that with the increasing number of blocks and transactions, the proposed data traceability mechanism maintains satisfactory performance.…”
Get full text

Ion Channels and Zinc: Mechanisms of Neurotoxicity and Neurodegeneration by Deborah R. Morris, Cathy W. Levenson

“…This paper discusses the role of the excitotoxic influx and accumulation of zinc, the mechanisms responsible for its cytotoxicity, and a number of disorders of the central nervous system that have been linked to these neuronal ion channels and zinc toxicity including ischemic brain injury, traumatic brain injury, and epilepsy.…”
Get full text

INNOVATIVE DEVELOPMENT OF MECHANICAL ENGINEERING OF THE RUSSIAN FEDERATION by M. Tomova, L. Dedusheva

Get full text

Kinetics and mechanism of synthetic CoS oxidation process by Štrbac N., Mihajlović I., Živković D., Boyanov B., Živković Ž., Cocić M.

“…The results of investigation of kinetics and mechanism for synthetic a-CoS oxidation process are presented in this paper. …”
Get full text

THE MECHANISM OF PROFESSIONAL JUDGMENT IN REALIZATION OF THE PRINCIPLES OF ACCOUNTING by S. Ponomareva, V. Mironenko

“…This article is devoted to a research of questions of professional judgment in realization of the principles of accounting, to formation of the mechanism of approaches to a regulation of activity of the accountant directly during the choice of options of conducting account. …”
Get full text