Mechanism of <italic>Hedyotis Diffusa</italic> in Treatment of Osteosarcoma based on Network Pharmacology and Molecular Docking by Qin LIU, Xinwei DUAN, Xihai LI

“…Objective:To explore the mechanism of intervention of Hedyotis diffusa on osteosarcoma by network pharmacology and molecular docking.Methods:The active components and related targets of Hedyotis diffusa were predicted through the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP), while, osteosarcoma-related genes were obtained through Gene Expression Omnibus database. …”
Get full text

Study on Selfish Node Incentive Mechanism with a Forward Game Node in Wireless Sensor Networks by Mohammed Ahmed Ahmed Al-Jaoufi, Yun Liu, Zhen-jiang Zhang, Lorna Uden

“…We present a new model for the selfish node incentive mechanism with a forward game node for wireless sensor networks, and we discuss applications of the replicator dynamics mechanism to analyze evolutionary trends of trust relationships among nodes. …”
Get full text

Alzheimer’s disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA roles by Seyyed Sam Mehdi Hosseininasab, Rasoul Ebrahimi, Shirin Yaghoobpoor, Kiarash Kazemi, Yaser Khakpour, Ramtin Hajibeygi, Ashraf Mohamadkhani, Mobina Fathi, Kimia Vakili, Arian Tavasol, Zohreh Tutunchian, Tara Fazel, Mohammad Fathi, Mohammadreza Hajiesmaeili

“…This article provides an overview of the association between AD and various infectious agents, with a focus on the mechanisms by which these pathogens may be related to the pathogenesis of AD. …”
Get full text

Mechanical Characterization of Biocomposites Reinforced with Untreated and 4% NaOH-Treated Sisal and Jute Fibres by D. P. Archana, H. N. Jagannatha Reddy, Basavaraju Paruti

“…In this work, the biocomposites reinforced with sisal and jute fibres which are made by hand layup technique were investigated for mechanical and water absorption characteristics. The effect of a 4 percent NaoH treatment concentration on the aforementioned properties was investigated. …”
Get full text

Study on the Synchronous Instability Mechanism of the Coal Wall and Direct Roof of High Soft Coal Seam by Baojie Fu, Jiawen Li, Min Tu, Ningping Jin

“…The degree of coal wall failure and the depth of the plastic fracture zone are closely related to the advanced mining stress. The mechanical analysis model is established, and the stress distribution in the fracture and plastic zone is analyzed by the elastic-plastic theory, and the depth function expressions of two zones are determined. …”
Get full text

Mechanism analysis of the enhanced corrosion resistance of the Mg–2Y alloy after Mn addition by Jinhang Dong, Yuxiu Zhang, Jun Liang, Zonghui He, Xiangbin Li, Fei Long

Subjects: Get full text

Molecular Mechanism of Macrophage Activation by Red Ginseng Acidic Polysaccharide from Korean Red Ginseng by Se Eun Byeon, Jaehwi Lee, Ji Hye Kim, Woo Seok Yang, Yi-Seong Kwak, Sun Young Kim, Eui Su Choung, Man Hee Rhee, Jae Youl Cho

“…In this study, we aimed to explore the mechanism of molecular activation of RGAP in macrophages. …”
Get full text

Neural mechanisms of fairness decision-making: An EEG comparative study on opportunity equity and outcome equity by Qi Li, Ya Zheng, Jing Xiao, Kesong Hu, Zhong Yang

“…Our study used a modified version of the ultimatum game (UG) and the classic UG, and recorded electroencephalogram (EEG) data to investigate underlying neural mechanisms of fairness decision-making of opportunity equity and outcome equity. …”
Get full text

The Cu–Sn multilevel gradient heterogeneous interface interpenetrative growth mechanism and its regulation strategies by Yulu Ouyang, Yahui Liu, Guoshang Zhang, Tao Huang, Weiwei Lu, Dong Liu, Aikui Liu, Kexing Song

Get full text

Study on the Influence Mechanism of Servo Gain Parameter on the Pitch Deviation Error of Tool Retracting Position by Zhao Chunhua, Liang Zhipeng

Get full text

A Review on the Effect of Various Chemical Treatments on the Mechanical Properties of Renewable Fiber-Reinforced Composites by M. Aravindh, S. Sathish, R. Ranga Raj, Alagar Karthick, V. Mohanavel, Pravin P. Patil, M. Muhibbullah, Sameh M. Osman

“…However, biofibers are also having some limitations that need to be addressed including poor compatibility between the reinforcing fiber matrices, high moisture absorption, swelling, poor chemical and fire resistance, and high dispersion of mechanical properties. A lot of research has been performed on physical and mechanical properties of natural fiber composite. …”
Get full text

Study on the Deformation Mechanism of Soft Rock Roadway under Blasting Disturbance in Baoguo Iron Mine by Hong-di Jing, Yuan-hui Li, Kun-meng Li

“…In order to study the deformation mechanism of soft rock roadway in underground mines, it is necessary not only to study the influence of the dynamic disturbance caused by the cyclic mining blasting vibration on the stability of the soft rock roadway but also to study the degradation of the roadway surrounding rock itself and other factors. …”
Get full text

Evaluation of Extra-High Translucent Dental Zirconia: Translucency, Crystalline Phase, Mechanical Properties, and Microstructures by Hiroto Nakai, Masanao Inokoshi, Hengyi Liu, Motohiro Uo, Manabu Kanazawa

“…In this study, we assessed the translucency, crystalline phase, mechanical properties, and microstructures of three newly developed highly translucent zirconia materials (Zpex 4. m, 4 mol% yttria-stabilized zirconia: 4YSZ; Zpex Smile.m, 5YSZ; ZR Lucent ULTRA, 6YSZ). …”
Get full text

An Improved Sequential Recommendation Algorithm based on Short-Sequence Enhancement and Temporal Self-Attention Mechanism by Jianjun Ni, Guangyi Tang, Tong Shen, Yu Cai, Weidong Cao

“…To address the above problems, an improved sequential recommendation algorithm based on short-sequence enhancement and temporal self-attention mechanism is proposed in this paper. In the proposed algorithm, a backward prediction model is trained first, to predict the prior items in the user sequence. …”
Get full text

Preparation of pH-Responsive Tanshinone IIA-Loaded Calcium Alginate Nanoparticles and Their Anticancer Mechanisms by Tianying Ren, Jing Wang, Yingxin Ma, Yichen Huang, Somy Yoon, Lijun Mu, Ru Li, Xuekun Wang, Lina Zhang, Pan Li, Lusha Ji

“…Further investigation into the molecular mechanisms revealed that the anticancer effects of Tan IIA/CA were mediated through apoptosis, ferroptosis, and autophagy pathways. …”
Get full text

Fatigue properties and fracture mechanism of load carrying type fillet joints with one-sided welding by Takamasa Abe, Hiroyuki Akebono, Masahiko Kato, Atsushi Sugeta

“…In this study, the fatigue properties and the fracture mechanism of the load carrying type fillet joints with one-sided welding were investigated experimentally to evaluate its fatigue damage with high accuracy based on the experimental results. …”
Get full text

Prone Position after Liberation from Prolonged Mechanical Ventilation in COVID-19 Respiratory Failure by Andrei Karpov, Anish R. Mitra, Sarah Crowe, Gregory Haljan

“…Prone positioning of nonintubated patients has prevented intubation and mechanical ventilation in patients with respiratory failure from coronavirus disease 2019 (COVID-19). …”
Get full text

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms by David Trombley McSwiggen, Helen Liu, Ruensern Tan, Sebastia Agramunt Puig, Lakshmi B Akella, Russell Berman, Mason Bretan, Hanzhe Chen, Xavier Darzacq, Kelsey Ford, Ruth Godbey, Eric Gonzalez, Adi Hanuka, Alec Heckert, Jaclyn J Ho, Stephanie L Johnson, Reed Kelso, Aaron Klammer, Ruchira Krishnamurthy, Jifu Li, Kevin Lin, Brian Margolin, Patrick McNamara, Laurence Meyer, Sarah E Pierce, Akshay Sule, Connor Stashko, Yangzhong Tang, Daniel J Anderson, Hilary P Beck

“…With this one experimental modality, we determined the potency, pathway selectivity, target engagement, and mechanism of action for identified hits. Kinetic htSMT experiments were capable of distinguishing between on-target and on-pathway modulators of ER signaling. …”
Get full text

The Mechanisms of Inclusive Leadership on Newcomers’ Proactive Socialization Behaviors—An Exploration Based on the Proactive Motivation Model by Jingyi Shi, Long Ye, Junnan Ren

Get full text

TECHNOLOGICAL ASSURANCE OF MECHANICAL PROCESSING OF COMPLEX SHAPED PARTS BASED ON MACHINING CENTERS WITH NUMERICAL CONTROL by BÎCIOC, Mihail

“…The present study focuses on technological assurance of the mechanical processing of complex-shaped parts on Computer Numerical Control (CNC) machining centers. …”
Get full text