Effect of Body Weight Supported Treadmill Training on Motor Function of Rats with Spinal Cord Injury Based on AMPK-Autophagy Signaling Pathway by CAI Jili, ZHAI Chenyuan, WANG Zun, WU Qi, FANG Lu, WANG Yu, WANG Tong

“…ObjectiveTo explore the effect and mechanism of body weight supported treadmill training on motor function of rats with spinal cord injured (SCI) based on the adenosine monophosphate-activated protein kinase (AMPK)-autophagy signaling pathway.MethodsA total of 30 10-week-old female SD rats were randomly divided into sham operation group, model group, and exercise group, with 10 cases in each group. …”
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Effect of Electroacupuncture Preconditioning on Inflammatory Factors of Rabbits after Spinal Cord Ischemia-Reperfusion Injury by Mengli YAO, Xianghua CHEN, Zhaohui CHEN, Hai WANG

“…Objective:To observe the effects of electroacupuncture preconditioning on the pathological changes of spinal cord tissue and the expression of inflammatory cytokines such as interleukin-1β(IL-1β), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α), interleukin-1 receptor antagonist(IL-1Rα)after spinal cord ischemia-reperfusion injury, and to explore the protective mechanism of electroacupuncture on spinal cord ischemia-reperfusion injury in rabbits.Methods:A total of twenty-four New Zealand white rabbits were randomly divided into the sham operation group, the model group and the electroacupuncture group according to the random number table method, with eight cases in each group.The model was made by Zivin method in the model group and the electroacupuncture group, the abdominal cavity was opened after intravenous anesthesia at ear margin, the abdominal aorta was exposed and temporarily clamped, and the rabbit model of spinal cord ischemia-reperfusion injury was established after ischemia for thirty minutes.The model preparation and experimental animal treatment of the sham operation group were the same as those of the model group, however, the dissection was fully exposed without clamping the abdominal aorta.At thirty minutes before the induction of rabbit spinal cord ischemia-reperfusion model, SDZ-II electroacupuncture instrument was used to acupuncture bilateral"Xuanzhong"and"Yanglingquan"acupoints in the electroacupuncture group, intervention for thirty minutes.All rabbits were killed after intervention for twelve hours, and the L2-5 segments of spinal cord tissue were captured.HE staining method was used to observe the pathological changes of spinal cord tissues in the three groups; Immunohistochemical method was used to observe the localization and content changes of IL-1β, IL-6 and TNF-α; Enzyme-linked immunosorbent assay(ELISA)was used to detect the contents of IL-1β, IL-6, TNF-α and IL-1Rα in serum before modeling and 4, 8, 12 hours after ischemia-reperfusion.Results:①HE staining results: compared with the sham operation group, the number of neurons in spinal cord tissue in the model group decreased, the color of nucleus and cytoplasm of cells became lighter, and the boundary of nuclear membrane was not clear.In severe cases, the nucleus dissolved or even nucleolus disappeared, there were transparent areas around cells, and axons showed different degrees of degeneration such as enlargement, swelling and disappearance; compared with the model group, the number of neurons in the electroacupuncture group increased, the structure of most neurons was clear, the atrophy degree of nucleolus and nucleus was light, only a small amount of cells became deformed and necrosis, the damage degree of cells were lighter, and the density of surviving neurons increased.②Immunohistochemistry results: compared with the sham operation group, the expressions of IL-1β, IL-6 and TNF-α of spinal cord tissue in the model group were significantly increased(<italic>P</italic>&lt;0.05);compared with the model group, the contents of IL-1β, IL-6 and TNF-α in the spinal cord of rabbits in the electroacupuncture group were significantly decreased(<italic>P</italic>&lt;0.05).③ELISA results: Before modeling, there was no significant difference in the three groups(<italic>P</italic>&gt;0.05);compared with before modeling, the expressions of IL-1β, IL-6, TNF-α, IL-1Rα in serum of the three groups increased in different degrees at 4, 8 and 12 h after ischemia-reperfusion, with significantly significance(<italic>P</italic>&lt;0.05);compared with the sham operation group at the same time, the expressions of IL-1β, IL-6, TNF-α and IL-1Rα in the model group increased significantly at 4, 8 and 12 h after reperfusion(<italic>P</italic>&lt;0.05);compared with the model group at the same time, the expression of IL-1β and TNF-α in the electroacupuncture group decreased significantly at 4, 8, 12 h after reperfusion(<italic>P</italic>&lt;0.05).Conclusion:Electroacupuncture pretreatment can effectively alleviate the pathological injury of spinal cord and has a good protective effect on spinal cord ischemia-reperfusion injury, which may be related to inhibit the expression of IL-1β, IL-6 and TNF-α and promote the expression of IL-1Rα.…”
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Evolution, Characteristics and Inspirations of Management Zoning for National Parks in the United States by Zhenwei ZHANG, Hanyue XIAO, Yankang MAO

“…Besides, management rules should be refined to enhance the adaptability. 3) Procedurally, the delineation and adjustment of zoning should be incorporated into the management plan, and the mechanisms for periodic assessment of planning and zoning should be incorporated into the legislation to summarize problems and rectify them in a timely manner. 4) The integrity of top-level policy design should be strengthened. …”
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Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

“…To confirm whether NL-SDT can reduce hypertensive renal fibrosis and its mechanism. The mice model of hypertensive renal fibrosis was established by using osmotic minipumps (Alzet model 2004, Cupertino, CA) equipped with angiotensin-II (Ang II). …”
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Changes of Narrative: Osvald Sirén’s Photographic Modeling of Modern Research on Chinese Garden by Jiuwen GU, Yuanfeng SHI, Shan JIA

“…As an emerging image material and a way to understand and review gardens, photography has driven a shift in gardening research, with the underlying mechanisms being investigated in this research. In addition, the research also explores the interaction between photography’s technical characteristics and gardens’ spatial characteristics.MethodsThis research adopts the case study of Osvald Sirén’s photographic images of Chinese gardens. …”
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Characteristics of the Volunteer Service Management System for National Parks in the United Kingdom by Tianyi REN, Chuanbo HONG, Yinglin WANG

“…Meanwhile, on the basis of literature review, this research searches relevant official data on the first batch of national parks announced in China, analyzes such contents as management documents, activity management, and personnel recruitment management, and compares the same horizontally with the volunteer service management system for national parks in the UK so as to analyze the shortcomings of the volunteer service management system for national parks in China and put forward corresponding suggestions.ResultsThe research finds that the 14 national parks in the UK have sound volunteer service management policies, management system structures and volunteer recruitment websites, as well as open and transparent volunteer screening mechanisms and volunteer feedback channels. In addition, most of the national parks have public data on the management of volunteer service funds, and a small number of national parks have public statistics on the number of volunteers and the total number of volunteer hours per year. …”
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Jiangu Granules Regulates Endoplasmic Reticulum Stress-Induced Apoptosis in UMR-106 Cells by Modulating the PERK/eIF2α/ATF4/CHOP Pathway by CHEN Sainan, ZHOU Fen, HUANG Yunmei, LIN Yanping

“…ObjectiveTo observe and analyze the mechanism by which Jiangu Granules containing serum alleviate endoplasmic reticulum stress (ERS)-induced apoptosis in UMR-106 osteoblast-like cells.MethodsUMR-106 osteoblast-like cells were selected for the study, and various concentrations (0, 0.01, 0.02, 0.03, 0.04, 0.05 μmol/L) of GSK2606414 (PERK inhibitor) were employed to intervene in the cells. …”
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Topological Analysis of Brain Glucose Metabolic Connectivity Networks of Patients with Type 2 Diabetes Mellitus Combined with Mild Cognitive Impairment by LIANG Shengxiang, YANG Junchao, ZHANG Yusi, YIN Xiaolong, HUANG Li, LI Zuanfang

“…The nodal local efficiencies of left hippocampal (<italic>r</italic>=-0.363, <italic>P</italic>=0.002) and left parahippocampal gyrus (<italic>r</italic>=-0.362, <italic>P</italic>=0.002) were negatively correlated with EcogSPMem score.ConclusionThe abnormal topological structure of brain glucose metabolic connectivity network in patients with T2DM&amp;MCI might be one of the reasons for the decline in memory, which could provide a reference for the exploring of the neural mechanism of patients with T2DM&amp;MCI.…”
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The role of teachers and administrators in supporting the adaptation of students with special needs in mainstream high schools by Amir Mahmood, Xiao Huang, Nadia Rehman

“…Schools should prioritize developing comprehensive support systems that include robust teacher support mechanisms and strong administrative backing. Professional development programs should focus on enhancing teachers’ skills in differentiated instruction, formative assessment and the use of technology in the classroom. …”
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Componentes y Dinámica Natural del Ambiente - Ciudad de Neuquén- by Olga Capua, Elsie Marcela Jurio

“…Under the prevailing climatic conditions, soil pedogenic processes are weak or allowing the initial processes of weathering or weathering, act directly on the rocky outcrops influencing modeling. The mechanical breakdown and gravitational movements, generate from the initial slope, new landforms characterized by the deposition of debris, masking en some sectors, the original lithology. …”
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Effects of Exercise Preconditioning Mediating Oxidative Stress to Regulate PI3K/Akt and Nrf2/HO-1 Pathways to Alleviate Cognitive and Learning Disorders in Rats by KONG Haijun, LI Xinlong, WANG Fenghua, CHEN Xiaoan

“…ObjectiveTo explore the basic mechanism of exercise preconditioning regulating PI3K/Akt and Nrf2/HO-1 signa-ling pathways and oxidative stress to alleviate cognitive and learning disabilities in rats with hypoxic exposure.MethodsA total of sixty 6-week-old SPF male SD rats were divided into control group, exercise group, exposure group and exercise + exposure group according to random number table method, with 15 rats in each group. …”
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Characteristics of Traditional Human Settlement Landscapes on Bedrock Islands in Guangdong Based on the “Ao” Unit by Ying PAN, Linxi CHEN, Ying SHI

“…ObjectiveThe objective of this research is to contribute to the strategic goal of transforming China into a strong maritime nation by enhancing the understanding and management of the ocean, and by fostering innovation in marine science and technology. …”
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Grape Recognition and Localization Method Based on 3C-YOLOv8n and Depth Camera by LIU Chang, SUN Yu, YANG Jing, WANG Fengchao, CHEN Jin

“…The integration of the CBAM and CA attention mechanisms into the YOLOv8n backbone resulted in mAP values of 93.5% each. …”
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Role of a key microphysical factor in mixed-phase stratocumulus clouds and their interactions with aerosols by S. S. Lee, S. S. Lee, S. S. Lee, C. H. Jung, J. Choi, Y. J. Yoon, J. Um, J. Um, Y. Zheng, J. Guo, M. G. Manoj, S.-K. Song

“…This examination is performed using a large-eddy simulation (LES) framework and is one of the efforts toward a more general understanding of mechanisms controlling cloud development and aerosol–cloud interactions, as well as the impacts of ice processes on them in mixed-phase stratocumulus clouds. …”
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Medical Jousting: Going for the kill! by Dr.Fuad Ahmed Khan Niazi

“…Medical Jousting may also be due to a lack of knowledge about other specialties in the context of multidisciplinary patient care or, it may just be a defensive mechanism to bail out of a complication; why not just blame it on someone else!!…”
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Pathways Through Which Green Exposure Type Influences Cardiovascular Diseases Mortality in Shanghai, China by Jianzhong HUANG, Yanting XU, Lan WANG, Zhouqian HE

“…Building density, in particular, can indirectly influence the influence of green exposure on CVDs mortality by modulating physical activity levels as a mediating factor.ConclusionThis research offers an in-depth analysis of the complex mechanisms by which various types of green exposure influence CVDs mortality, with a particular focus on the key mediating role of physical activity. …”
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Lightweight Daylily Grading and Detection Model Based on Improved YOLOv10 by JIN Xuemeng, LIANG Xiyin, DENG Pengfei

“…AKVanillaNet combines AKConv (adaptive kernel convolution) with VanillaNet's deep learning and shallow inference mechanisms. The second convolutional layer in VanillaNet was replaced with AKConv, and AKConv was merged with standard convolution layers at the end of the training phase to optimize the model for capturing the unique shape characteristics of dried daylilies. …”
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Analysis of the Rights and Obligations of Stakeholders in China’s National Park Concession System by Le ZHONG, Zhicong ZHAO

“…The research uncovers that the current system falls short in addressing the community’s rights, particularly concerning active engagement in concession activities and benefit-sharing mechanisms. The research concludes with a set of recommendations to explicitly integrate stakeholder qualifications, rights, and obligations into legislation at multiple levels, establish concession systems grounded in the principle of right-obligation equivalence, and ensure the full realization of community rights within the national park concession system.ConclusionThis research conducts a thorough analysis of stakeholders in China’s concession framework, encompassing such shareholders as grantors, concessionaires and supervisory entities, from the three levels of “ought to be”, “is” and “enabled to be”. …”
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Predicting Insemination Outcome in Holstein Dairy Cattle using Deep Learning by Mohammad Alishahi, Mahdi Ravakhah

“…This ability is attributed to the unique structure of LSTM and its gate mechanisms, which enable the network to filter out irrelevant information while retaining essential information. …”
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Dense Nursery Stock Detecting and Counting Based on UAV Aerial Images and Improved LSC-CNN by PENG Xiaodan, CHEN Fengjun, ZHU Xueyan, CAI Jiawei, GU Mengmeng

“…Secondly, the convolutional block attention module (CBAM) attention mechanism was introduced at the beginning of each scale branch. …”
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