Effect of Ginkgolide B on Non-Alcoholic Fatty Liver Disease based on Notch Signaling Pathway by Hong YU, Junzi WU, Bo SONG, Jun LI

“…Compared with the model group, the number of fat vacuoles in the simvastatin group, high, medium, and low dose group decreased significantly (<italic>P</italic>&lt; 0.05). ③The protein and mRNA expression of Notch-3 and Hes-1: compared with the normal group, the protein and mRNA expression of Notch-3 and Hes-1 in the model group increased significantly (<italic>P</italic>&lt; 0.05); compared with the model group, the protein and mRNA expression of Notch-3, Hes-1 in the simvastatin group, low and medium high-dose group decreased significantly (<italic>P</italic>&lt; 0.05); compared with the simvastatin group, the protein and mRNA expression of Notch-3, Hes-1 of the medium and high-dose group decreased significantly (<italic>P</italic>&lt; 0.05).Conclusion:Ginkgolide B can improve the liver function, reduce blood lipids, and reduce inflammation of NAFLD rats. Its mechanism may be that Ginkgolide B could regulate the Notch signaling pathway by inhibiting Notch-3, Hes-1 protein and mRNA expression in liver tissue.…”
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Educide amid conflict: the struggle of the Palestinian education system by Dalal Iriqat, Rula Alousi, Tahani Z. Aldahdouh, Alaa AlDahdouh, Iman Dankar, Dima Alburai, Mohamed Buheji, Abdo Hassoun

“…Highlighting the concept of “Educide”, the study calls for policies to prevent the targeting of educational institutions in conflict zones and mechanisms to hold perpetrators accountable. It advocates for comprehensive support to rebuild Gaza’s educational infrastructure, ensuring students and educators can safely return to learning environments. …”
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Field intercomparison of ice nucleation measurements: the Fifth International Workshop on Ice Nucleation Phase 3 (FIN-03) by P. J. DeMott, J. A. Mirrielees, J. A. Mirrielees, S. S. Petters, S. S. Petters, S. S. Petters, D. J. Cziczo, D. J. Cziczo, M. D. Petters, M. D. Petters, M. D. Petters, H. G. Bingemer, T. C. J. Hill, K. Froyd, K. Froyd, K. Froyd, S. Garimella, S. Garimella, A. G. Hallar, A. G. Hallar, E. J. T. Levin, E. J. T. Levin, I. B. McCubbin, I. B. McCubbin, A. E. Perring, A. E. Perring, A. E. Perring, C. N. Rapp, T. Schiebel, T. Schiebel, J. Schrod, K. J. Suski, K. J. Suski, D. Weber, D. Weber, M. J. Wolf, M. J. Wolf, M. Zawadowicz, M. Zawadowicz, J. Zenker, J. Zenker, O. Möhler, S. D. Brooks

“…Additionally, some measurements were made in the deposition nucleation regime at these same temperatures, representing one of the first efforts to include both mechanisms within a field campaign. INP concentrations via immersion freezing agreed within factors ranging from nearly 1 to 5 times on average between matched (time and temperature) measurements, and disagreements only rarely exceeded 1 order of magnitude for sampling times coordinated to within 3 h. …”
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Experimental Study of Modified Videman Method to Replicate Knee Osteoarthritis in Rabbits by Jing LIU, Qiaoxuan LIN, Liming LU, Zexing GUO, Hong LIU, Liangzhi ZHANG, Zhongbiao XIU

“…There was no significant difference in morphology between the traditional group and the improved group (<italic>P</italic>&gt;0.05).5) Comparison of the average time taken to fix and disassemble the plaster: the average time of the improved group was significantly shorter than that of the traditional group (<italic>P</italic>&lt;0.05).Conclusion:The KOA rabbit model established by modified Videman method has the advantages of simple operation, firm fixation, convenient disassembly and high success rate of modeling, which is conducive to the study of KOA mechanism.…”
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Molecular Epidemiological Characteristics of blaIMP-4-Carrying Klebsiella pneumoniae ST-11 in Hospitalized Patients by Xue YE, Zhang D, Du S, Chen D, Liu S, Peng T, Li C, Zhang J, Wang X

“…Patients with ST-11 CRKP underwent more mechanical ventilation (50% vs 32.9%, P=0.020) and gastric catheterization (15.7% vs 6.1%, P=0.042) within 3 months before sample collection, and also had higher drug-resistance rate than non-ST-11 CRKP. …”
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"Spirit in a world without spirit": Foucault's interpretation of the Iranian Revolution and resistance to western modernity by Urošević Milan

“…A certain number of authors also agree on the interpretation that sees inconsistency in Foucault's study of the Iranian Revolution, as they believe that at this point, he abandons his understanding of power as a totalizing mechanism and introduces the idea of a free acting subject. …”
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Review of the Handbook of Accounting, Accountability and Governance edited by Garry D. Carnegie and Christopher J. Napier by Anna Szychta

“…He emphasized that the importance of accounting “lies in its function as a cybernetic mechanism (a feedback that controls and regulates) that preserves confidence in the trustees of public and private resources and financial markets no less than in the entire economic system” (Mattessich, 1995, p. 2). …”
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Tax Exemptions and R;D Expenditures in Iran Saeed Dorokhshi Moghaddam by Saeed Dorokhshi Moghaddam, Bahram Sahabi, Hassan Heydari, Sajad Barkhordari

“…To effectively support knowledge-based companies and to create a more R&D-intensive country, it is not enough to solely provide tax exemptions for firms. However, mechanisms must be in place to foster reaching much more qualified human resources and to a greater extent finance. …”
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Acute phase responses in clinically healthy multiparous Holsteins with and without calcium dysregulation during the early postpartum period by J.A. Seminara, C.R. Seely, J.A.A. McArt

“…Although the causal structure of this relationship remains unknown, improved understanding of inflammation and dyscalcemia may provide insight into mechanisms by which some cows experience maladaptation during the early postpartum period.…”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…Our findings reinforce the need for larger, more definitive studies to confirm these associations and to explore the mechanisms by which these drugs may contribute to PV development. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…One of the possible protective mechanisms of these plants is their antioxidant property, which prevents the activity of free radicals produced by aflatoxin B1.Conclusion: The results of the present study indicate that the use of garlic extract at the rate of 50 mg/kg of body weight, turmeric extract at the rate of 100 mg/kg of body weight, and their combination reduces the level of toxicity caused by aflatoxin B1. …”
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Sources of right to freedom of peaceful assembly by М. А. Sambor

“…In order to understand and form the legal basis and mechanism (algorithm) for exercising the right to freedom of peaceful assembly, it is important to understand the origins of this right and to substantially fill the right to freedom of peaceful assembly. …”
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Pengaruh Hiperglikemia terhadap Gambaran Histopatologis Pulau Langerhans Mencit by Muhammad Farid, Eryati Darwin, Delmi Sulastri

“…Islet density was slightly increased in all treated group (p&lt;0.05) through mechanism of neogenesis. The result suggest that hyperglycemia induced by administration of different doses of glucose intraperitoneally for 14 days caused significant changes in histopathological features of mice pancreatic islet.…”
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Presenting the indigenous model of organizational self-leadership with an emphasis on training in non-governmental organizations by Sajad Ghoreishi, abbas abbaspour, Mostafa Niknami, Morteza Taheri

“…What should be done to train efficient leaders in organizations? What is the mechanism of leadership development in organizations? …”
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Crocin Alleviates Hippocampal Neuron Injury in Rats with Cerebral Ischemia-Reperfusion by Inhibiting JAK2/STAT3 Signaling Pathway by LI Xiaolei, ZHU Haisheng, MA Ruijuan, YAO Li, HU Ke, FENG Lina, WANG Xudong

“…ObjectiveTo investigate the effect of Crocin (CRO) on rats with hippocampal neuron cerebral ischemia reperfusion (CI/R) injury and explore its potential mechanism.MethodsA total of 144 male SD rats were selected and randomly divided into sham group, model (CI/R) group, CRO low-, medium-, high-dose (CRO-L, CRO-M, CRO-H) group and Nimodipine (NMP) group, with 24 rats in each group. …”
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Human Capital, Economic Growth and Environmental Quality with Special Emphasis on Public Education Expenditures: An Application of DSGE Models by Yahya Mohaghegh, hashem zare, Mehrzad Ebrahimi

“…Theoretical studies emphasize different mechanisms through which education affects economic growth. (1) Education increases the human capital of the labor force, thereby increasing labor productivity and shifting growth toward a higher equilibrium level of output. (2) In endogenous growth theories, education increases the economy's capacity to innovate new technologies, products, and processes, thereby promoting growth. …”
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Personalized approach in the management of women with heart failure with preserved ejection fraction and carbohydrate metabolism disorders by L.R. Petrovska, I.O. Kostitska, T.R. Petrovskyy, R.V. Petrovskyy

“…Due to both heterogeneity and syntropy of etiopathogenetic mechanisms of occurrence, the prevalence of DM and HF is increasing in the world population, and delayed treatment potentiates a poor prognosis. …”
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Hubungan Kadar LDL dan HDL Serum Ibu Hamil Aterm dengan Berat Lahir Bayi by Oktalia Sabrida, Hariadi ., Eny Yantri

“…Uptake and usage of LDL by placenta to the fetus is an alternative mechanism to obtain fatty acids and essential amino acids. …”
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Analyzing Expressions of the Design Argument and Answering Doubts Attributed to it Based on the Type of Logical Reasoning by Shokoh Monazzam, Abbas Abbaszadeh, Naser Forouhi

“…Therefore, real believers would not conclude the existence of a contriver creature in the design argument based on knowing the world as a mechanical one but perceive an intelligent cause based on definite and obvious rules like causality and cause-effect suitability.…”
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The Anisotropic Time-Dependent Properties and Constitutive Model Analysis of Carbonaceous Slate with Different Foliation Angles by Yuanguang Zhu, Xuanyao Wang, Bin Liu, Haoyuan Xue

“…The results provide a reference for the study of the creep mechanism of layered rocks.…”
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