Methodological approach to assessing the competitiveness of the region's manufacturing sector by Khmeleva Galina, Skreblov Nikita

“…The results of the study made it possible to confirm the decrease in the level of technological dependence in the regions, since, compared to others, the geography of specializations in the production of electronic equipment and mechanical engineering is expanding at the fastest pace. …”
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Differentiation status determines the effects of IFNγ on the expression of PD-L1 and immunomodulatory genes in melanoma by Teitur Sævarsson, Adrián López García de Lomana, Ólafur Sánchez, Veerle van Esch, Gunnar Bjarni Ragnarsson, Siggeir Fannar Brynjólfsson, Eiríkur Steingrímsson, Berglind Ósk Einarsdóttir

“…Inhibition of the JAK kinases, NF-κB and STAT3 with small molecule inhibitors, and siRNA mediated knockdown of STAT1 and IRF1 was applied to investigate the molecular mechanism behind IFNγ induced PD-L1 expression in dedifferentiated melanoma cells. …”
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Effect of gestational age on clinical features in necrotizing enterocolitis-associated intestinal perforation by Minming Chen, Wei Feng, Jinping Hou, Xiaohong Die, Zhenhua Guo, Yi Wang

“…For related treatment, the usage rate of vasoactive substances and mechanical ventilation in Group 1 was higher than that of Group 2 and Group 3 (all P < 0.016). …”
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Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Patients with Post-Stroke Comorbid Cognitive Impairment and Depression by YANG Jinghan, LI Yamei, YU Qian

“…Compared with the control group, gray matter density in the left head and face regions of precentral gyrus, and the left caudal area of middle temporal gyrus of the observation group were higher, while gray matter density in the left medioventral occipital cortex and right middle frontal gyrus were lower, and the difference was statistically significant (<italic>P</italic>&lt;0.05).ConclusionHigh-frequency rTMS can improve cognitive function and depression of patients with PSCCID, and the mechanism may be related to the increase of the gray matter density in local brain regions.…”
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Anogenital distance in water buffalo females and relationship with reproductive performance. Preliminary results by Héctor Nava-Trujillo, Simón Zambrano-Salas, Justin Dijak, Adriana Morgado-Osorio, Quintino D’Andrea

“…In the same direction, there is a need to carry out more research to clarify the mechanism involved in improving reproductive performance and the heritability of AGD. …”
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The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity by Daniel Torrente, Enming J. Su, Alí Francisco Citalán-Madrid, Gerald P. Schielke, Daniel Magaoay, Mark Warnock, Tamara Stevenson, Kris Mann, Flavie Lesept, Nathalie Delétage, Manuel Blanc, Erin H. Norris, Denis Vivien, Daniel A. Lawrence

“…To characterize the mechanism of tPA action in α-synuclein-mediated pathology in the SN and to identify possible therapeutic pathways, we performed RNA-seq analysis of the SN and used multiple transgenic mouse models. …”
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Spatial-Temporal Variation and Driving Forces of Carbon Storage at the County Scale in China Based on a Gray Multi-Objective Optimization-Patch-Level Land Use Simulation-Integrated... by Gui Chen, Qingxia Peng, Qiaohong Fan, Wenxiong Lin, Kai Su

“…This study deepened, to a certain extent, the research on spatiotemporal dynamics simulation of carbon storage and its driving mechanisms under land-use changes in mountainous forest ecosystems. …”
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Gonadotropin Releasing Hormone Agonists Combined with Hormone Replacement Therapy Significantly Improves Reproductive Outcomes for Patients with Thin Endometrium and Intramural Fib... by Wei L, Tian B, Wang S, Xu S, Zhang C

“…These findings provide valuable insights for exploration of the underlying mechanisms by which the GnRH-a-HRT protocol enhances reproductive outcomes in patients of thin endometrium with intramural fibroids.Keywords: frozen embryo transfer, live birth rate, clinical pregnancy rate, thin endometrium, intramural fibroid…”
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Understanding the use of the National Early Warning Score 2 in acute care settings: a realist review protocol by Nia Roberts, Geoff Wong, Michelle Treacy, Mandy Odell

“…Therefore, this review will use a realist approach to understand what the mechanisms are that influence appropriate use (or not) of the NEWS2 in acute care settings, how, for whom and in which contexts. …”
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Y2O3NPs induce selective cytotoxicity, genomic instability, oxidative stress and ROS mediated mitochondrial apoptosis in human epidermoid skin A-431 Cancer cells by Hanan RH Mohamed, Shrouk H.A Hemdan, Ahmed A. El-Sherif

“…This study was thus conducted to investigate the impact of Y2O3NPs on both human skin normal and cancer cells, with an emphasis on assessing their cytotoxicity, genotoxicity, and the mechanisms underlying these effects. Cell viability and apoptosis induction were assessed using the Sulforhodamine B and chromatin diffusion assay, respectively. …”
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Low-cost phone-based LiDAR scanning technology provides sub-centimeter accuracy when measuring the main dimensions of motor-manual tree felling cuts by Stelian Alexandru Borz, Andrea Rosario Proto

“…Commonly, it requires a sequence of cuts and may cause higher volume losses compared to mechanized tree felling. The wood lost depends also on the tree size, but accurate quantifications and their dependencies are difficult to establish since there is a limited ability to manually measure key dimensions and assimilate the tree bottom to parametric geometric features. …”
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Sport commitment among children and adolescent through the lens of theory of organismic integration: A systematic literature review by Anna Pavlova

“…Discussion/Conclusion The mechanism of internalization of external motivational influences and the factors affecting this process are still understudied. …”
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Hairy transcriptional repression targets and cofactor recruitment in Drosophila. by Daniella Bianchi-Frias, Amir Orian, Jeffrey J Delrow, Julio Vazquez, Alicia E Rosales-Nieves, Susan M Parkhurst

“…While a major step forward in understanding the molecular mechanism(s) surrounding Hairy-mediated repression was made with the identification of Groucho, Drosophila C-terminal binding protein (dCtBP), and Drosophila silent information regulator 2 (dSir2) as Hairy transcriptional cofactors, the identity of Hairy target genes and the rules governing cofactor recruitment are relatively unknown. …”
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De la neuroplasticidad a las propuestas aplicadas: estimulación temprana y su implementación en Costa Rica / From Neuroplasticity to Applied Proposals: Early Stimulation and Its Im... by Johanna Sibaja-Molina, Tracy Sánchez-Pacheco, Mijail Rojas-Carvajal, Jaime Fornaguera-Trías

“…., developmental psychology, neuroscience) describes not only how environment can modulate brain development and function, but also the plastic mechanisms involved. In consequence, different methodological approximations of early stimulation (ES) have arisen, although they are not necessarily based on solid empirical evidence. …”
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Impact of a positive end-expiratory pressure on oxygenation, respiratory compliance, and hemodynamics in obese patients undergoing laparoscopic surgery in reverse Trendelenburg pos... by Gulfairus A. Yessenbayeva, Aizhan M. Meyerbekova, Sergey I. Kim, Murat B. Zhumabayev, Gulbanu S. Berdiyarova, Sanzhar B. Shalekenov, Dinara S. Zharlyganova, Irina Y. Mukatova, Yekaterina A. Yukhnevich, Dmitriy A. Klyuyev, Andrey I. Yaroshetskiy

“…Abstract Background High and individual positive end-expiratory pressure (PEEP) during laparoscopic surgery may improve oxygenation and respiratory mechanics. Methods We searched RCTs in PubMed, Cochrane Library, Web of Science, and Google Scholar from from from January 2000 to December 2023 comparing the different intraoperative PEEP (low PEEP (LPEEP): 0–5 mbar; moderate PEEP (MPEEP): 6–9 mbar; high PEEP (HPEEP): >=10 mbar; individualized PEEP (iPEEP): PEEP set by special physiological technique) on arterial oxygenation, respiratory compliance (Cdyn) or driving pressure, mean arterial pressure (MAP), and heart rate (HR) in patients during laparoscopic surgery in reverse Trendelenburg position. …”
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A Meta analysis on effect of auricular point sticking and pressing therapy in the treatment of hyperemesis gravidarum (耳穴贴压法治疗妊娠恶阻临床疗效的Meta分析) by TIAN Tian (田恬), XIE Wei (谢薇), DENG Yunyan (邓云燕), LI zhongqing (李忠琴), ZHANG yang (张杨), ZHAO Su (赵苏)

“…Conclusion Auricular point sticking and pressing therapy is better than basic therapy in the treatment of hyperemesis gravidarum. However, the mechanism of auricular plaster therapy is not clear and needs to be studied. …”
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Molecular characterization of ST15 carbapenem-resistant Klebsiella pneumoniae isolated in a single patient by Yongjin Hu, Rong Tang, Shanshan Jin, Jiahao Guan, Xiaoxiao Meng, Zengpeijie Dan, Ruilan Wang, Hong-Yu Ou, Jian Lu

“…In this study, we analysed the clinical and molecular characteristics of drug resistance changes in KP strains isolated from a single patient, and the potential mechanisms underlying these resistance changes. Methods: Antimicrobial susceptibility test and string test were conducted to evaluate the resistant and virulent characterization of the strains. …”
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CCAAT/Enhancer-Binding Protein β Mediates Oxygen-Induced Retinal Neovascularization via Retinal Vascular Damage and Vascular Endothelial Growth Factor by Tingting Li, Xuan Cai, Xiangning Wang, Xueyan Zhang, Hui Zhang, Biwei Xu, Shiwei Li, Jianyan Hu, Qiang Wu

“…C/EBP β shRNA inhibits RNV in OIR. A potential mechanism may be that the activity of C/EBP β increases with its overexpression, which in turn aggravates the amount of the retinal vascular damage and promotes transcription of VEGF. …”
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Yeast cell wall polysaccharides accelerate yet in-feed antibiotic delays intestinal development and maturation via modulating gut microbiome in chickens by Fangshen Guo, Jianing Qiao, Zeqiong Hu, Jia Huang, Ruichen Bi, Waseem Abbas, Wenrui Zhen, Yuming Guo, Zhong Wang

“…This study aimed to investigate the effects of dietary yeast cell wall polysaccharides (YCWP) addition on intestinal development and maturation of chickens and its potential action mechanism. Methods 180 one-day-old male Arbor Acres broilers were randomly assigned to three groups containing control (basal diets without any antibiotics or anticoccidial drug), bacitracin methylene disalicylate (BMD)-treated group (50 mg/kg) and YCWP-supplemented group (100 mg/kg). …”
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Adherence to a digital therapeutic mediates the relationship between momentary self-regulation and health risk behaviors by Enzo G. Plaitano, Enzo G. Plaitano, Daniel McNeish, Sophia M. Bartels, Sophia M. Bartels, Kathleen Bell, Jesse Dallery, Michael Grabinski, Michaela Kiernan, Hannah A. Lavoie, Hannah A. Lavoie, Shea M. Lemley, Michael R. Lowe, David P. MacKinnon, Stephen A. Metcalf, Stephen A. Metcalf, Lisa Onken, Judith J. Prochaska, Cady Lauren Sand, Cady Lauren Sand, Emily A. Scherer, Luke E. Stoeckel, Haiyi Xie, Lisa A. Marsch

“…Self-regulation is one fundamental behavior change mechanism often incorporated within digital therapeutics as it varies momentarily across time and contexts and may play a causal role in improving these health behaviors. …”
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