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38561
Designing a Policy Making Model in Iran' Sport with the Approach of Sport for All Development
Published 2024-03-01“…In Iran, 'sport for all' and organized recreation have received limited attention, and currently, there is no mechanism for monitoring sports policies and their continuous implementation. …”
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38562
Glucagon, rather than Glucagon-Like Peptide 1, Mediates Higher Post-Lunch Glucose Excursions during Breakfast Skipping in Asian Indian Patients with Uncontrolled Type 2 Diabetes Me...
Published 2024-12-01“…Introduction: The effect and mechanism of skipping breakfast on glycemic control in type 2 diabetes mellitus (T2DM) in Asian-Indians is unknown. …”
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38563
Design of an improved model using federated learning and LSTM autoencoders for secure and transparent blockchain network transactions
Published 2025-01-01“…Integrity and authenticity requirements are fulfilled by enforcing consensus mechanisms. Privacy in Machine Learning is guaranteed through Differential Privacy and Homomorphic Encryption. …”
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38564
Assessment of hemodynamic disturbances and impaired ventricular filling in asymptomatic fontan patients: A 4D flow CMR study
Published 2025-06-01“…The study utilized cine images to analyze cardiac function and inter-ventricular mechanical dyssynchrony. Echocardiography evaluated functional ventricular diastolic dysfunction. …”
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38565
Source-specific acute cardio-respiratory effects of ambient coarse particulate matter exposure in California’s Salton Sea region
Published 2025-01-01“…Further research is needed to determine the underlying mechanisms responsible for these health impacts, as well as possible primary or secondary preventive strategies.…”
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38566
The Regulatory Effect of Se-Cd Interaction on Tea Plants (<i>Camellia sinensis</i> (L.) O. Kuntze) Under Cadmium Stress
Published 2025-01-01“…We measured and analyzed the electrolyte permeability, proline content, malondialdehyde (MDA) content, antioxidant-related indicators, photosynthesis-related indicators, Cd content in various organs, and transmission electron microscopy images depicting the distribution of Cd and Se elements within different organs of tea plants under these treatments after 30 days of processing, studying the regulatory role of selenium on the resistance mechanism of tea plants (<i>Camellia sinensis</i>) under cadmium stress. …”
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38567
Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice
Published 2025-01-01“…This study aims to investigate the impact of lactate intervention and its underlying mechanisms on epilepsy.Methods: HT22 cells were stimulated with glutamate to construct an excitotoxicity cell model. …”
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38568
The association between neighborhood social vulnerability and community-based rehabilitation after stroke
Published 2025-01-01“…Future studies should evaluate potential mechanisms for these findings and further identify both patient and community factors that may inform strategies to improve rehabilitation use. …”
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38569
Eicosapentaenoic Acid and Docosahexaenoic Acid as an Antimicrobial Agent in Orthopedics—An In Vitro Study About the Race for Surface
Published 2025-01-01“…Its capability of forming biofilms and developing mechanisms against antibiotics is one of the most dangerous clinical topics being currently discussed. …”
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38570
Salivary testosterone and cortisol responses to seven weeks of practical blood flow restriction training in collegiate American football players
Published 2025-01-01“…For the testosterone-to-cortisol ratio (T/C), AM pre-exercise was lower than PM (p < 0.05), with no change in post-exercise T/C for both AM and PM conditions when collapsed across testing times.DiscussionOverall, these findings suggest an ecologically valid method of BFR implementation is capable of inducing heightened concentrations of sTes in well-resistance trained American football athletes, providing additional insight on possible physiological mechanisms underpinning BFR’s ability to elicit beneficial muscle hypertrophy and maximal strength adaptations when performed during regimented training programs. …”
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38571
hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation
Published 2025-02-01“…Our study has further advanced the understanding of the molecular mechanism underlying muscle atrophy in weightlessness and has demonstrated the protective effect of hBMSC-EVs on muscle atrophy.…”
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38572
Research progress of auricular point therapy to relieve preoperative period anxiety before elective surgery in adults (耳穴压豆缓解成年人择期手术术前焦虑的研究进展)...
Published 2024-12-01“…Through literature review and analysis, this paper summarizes the application of auricular acupressure in alleviating preoperative anxiety among adults undergoing elective surgery and discusses its physiological mechanisms, providing a reference for clinical practice. …”
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38573
Common pathogenic aspects of diabetic retinopathy and nephropathy. Kidney transplantation and the course of diabetic retinopathy
Published 2021-05-01“…Key biological pathogenic mechanisms of microvascular complications involve over-production of reactive oxygen species and activation of intracellular signaling pathways and their modulators. …”
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38574
Airway pressures generated by high flow nasal cannula in patients with acute hypoxemic respiratory failure: a computational study
Published 2025-01-01“…Higher levels of PEEP could be beneficial if they lead to alveolar recruitment and improved lung compliance, but could cause alveolar overdistension if they do not, motivating the close monitoring of the effects of HFNC on lung mechanics. Further clinical studies are warranted to directly measure the airway pressures produced by HFNC in patients with different severities of AHRF.…”
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38575
Characterization of the bioaccumulation and toxicity of copper pyrithione, an antifouling compound, on juveniles of rainbow trout
Published 2024-01-01“…Among them, copper pyrithione (CuPT) is used, but its mechanisms of toxicity remain little known. This project aimed to identify and measure the impacts of aqueous exposure to CuPT, an organic compound, and compare it to ionic Cu2+ added in the form of its inorganic salt CuSO4, in equivalent Cu2+ molar concentrations, on rainbow trout (Oncorhynchus mykiss) juveniles under controlled laboratory conditions. …”
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38576
Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi...
Published 2025-02-01“…Haiou Wang,1 Wenkang Huang,1 Xiaoya Pan,1 Meizi Tian,1 Jiahui Chen,1 Xiaotong Liu,1 Qin Li,1 Jianhua Qi,2 Yiping Ye,1 Lijuan Gao1 1School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, People’s Republic of China; 2College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence: Lijuan Gao; Yiping Ye, Hangzhou Medical College, 182 Tianmushan Road, Hangzhou, Zhejiang, 310013, People’s Republic of China, Email gaolijuan04141002@126.com; yeyiping2005@163.comPurpose: To explore the protective effect and underlying mechanism of Quzhou Aurantii Fructus flavonoids (QAFF) on Ulcerative colitis (UC).Methods: The constituents of QAFF were accurately determined by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). …”
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38577
Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopulations in chronic atro...
Published 2025-02-01“…Abstract Purpose To identify key cellular changes and molecular events in atrophic mucosa, we aimed to elucidate the molecular mechanisms driving the occurrence of chronic atrophic gastritis (CAG). …”
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38578
Overcoming barriers to the development of clean and digital energy start-ups: access to credit and protection of minority investors' rights
Published 2024-12-01“…The study's primary aim is to analyse how financial mechanisms and governance safeguards influence start-up development in the clean and digital energy sectors. …”
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38579
Role of sphingolipid metabolism signaling in a novel mouse model of renal osteodystrophy based on transcriptomic approach
Published 2025-01-01“…ROD increases the risk of fracture and mortality in CKD patients. The underlying mechanisms of ROD remain elusive, partially due to the absence of an appropriate animal model. …”
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38580
A method for evaluating the accessibility of underground auxiliary transportation vehicles in coal mines based on multi feature fusion
Published 2024-12-01“…Progressive probability Hough transform and Catmull Rom spline curve with improved feature point selection are used to fit the straight track and curved track separately, forming a railway track detection method based on a switchable model; Secondly, based on the color attributes of coal mine underground tunnel wall pipelines, a pipeline feature detection strategy is constructed through HSV color space transformation, edge detection, and least squares fitting algorithms; Once again, a weighted fusion method based on pipeline and rail feature points is proposed to extract the centerline trajectory of auxiliary transportation vehicles, and to construct rules for generating safe passage areas for auxiliary transportation vehicles; Then, for the over-segmentation problem in the traditional watershed algorithm, two-dimensional edge and area feature extraction of static obstacles is carried out by using improved watershed segmentation based on markers and GraphCut algorithm, and a small-sample classification support vector mechanism is selected to build a pedestrian detection model based on the fusion of HOG (Histograms of Oriented Gradients)features and LBP(Local Binary Pattern) features for underground coal mine, so as to realize the comprehensive detection of dynamic and static obstacles in front of auxiliary transportation vehicles; Finally, the positional relationship between obstacles and safe passage area is judged by Euclidean distance to determine the obstacle invasion, and the results of auxiliary transportation vehicle passability assessment are obtained. …”
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