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38521
Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction
Published 2025-02-01“…This study aimed to investigate the potential biological mechanisms underlying POCD. Methods Male C57BL/6 mice (2 and 17 months old) were randomly assigned to surgery or control groups. …”
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38522
Overexpression of Parkin promotes the protective effect of mitochondrial autophagy on the lung of rats with exertional heatstroke
Published 2025-01-01“…Conclusion: Pink1/Parkin-mediated mitophagy dysfunction is one of the mechanisms underlying ALI in rats with EHS, and activation of Parkin overexpression-mediated mitophagy can alleviate ALI caused by EHS.…”
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38523
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus
Published 2025-02-01“…This pattern underscores the shared mechanisms involved in their immune responses and neurological complications, alongside dysregulation of the autophagy pathway. …”
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38524
Ethical leadership and nurses’ job performance: the mediating role of self-compassion
Published 2025-01-01“…Although the link between ethical leadership and nurse job performance has been established, the specific mechanisms that underlie this relationship remain unclear. …”
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38525
Characteristics and multi-omics analysis of spontaneous spondyloarthritis in non-human primates: Case report
Published 2025-01-01“…Its intricate pathological mechanisms have led to a scarcity of animal models capable of replicating the disease progression in humans, making it a prominent area of research interest in the field. …”
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38526
Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders
Published 2025-02-01“…To investigate the regulatory mechanism mediated by hypothalamic OPN5 on seasonal changes in the reproductive activities of domestic geese, 60 Magang ganders in their breeding period were selected for the experiment and evenly divided into an immunization group(OPN5-IM) and a control group. …”
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38527
Daya Tarik Selebriti Dalam Politik: Studi Kasus Rekrutmen Caleg Artis Oleh Partai NasDem Pada Pemilu 2019
Published 2024-12-01“…This study used a qualitative method through descriptive analysis to explain the recruitment mechanism carried out by the NasDem Party in the process of nominating legislative candidates. …”
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38528
PLGA-based biocompatible nanoparticles improved anti-breast tumor efficacy of 1,25(OH)2D3 through the SOCS3/STAT3/EMT signaling axis
Published 2025-03-01“…Hence, the potential of PLGA encapsulation to augment the anti-breast cancer properties of 1,25(OH)2D3 and the underlying mechanism remain uncertain. In this study, our findings not only demonstrated the effective encapsulation of 1,25(OH)2D3 in PLGA (PLGA-1,25(OH)2D3, PD) but also indicated that the PD has a more potent inhibitory effect on the proliferation and migration of breast cancer cells compared with 1,25(OH)2D3 alone. …”
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38529
Lightweight Detection and Counting of Maize Tassels in UAV RGB Images
Published 2024-12-01“…DLMNet features: (1) an efficient channel and spatial attention mechanism (ECSA) that suppresses high sunlight reflection noise and enhances details under low sunlight conditions, and (2) a dynamic feature fusion module (DFFM) that improves tassel recognition through dynamic fusion of shallow and deep features. …”
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38530
Identification of a potential homeodomain-like gene governing leaf size and venation architecture in birch
Published 2025-01-01“…To date, the molecular mechanisms governing leaf development including leaf venation patterning remains poorly understood in birch. …”
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38531
Polo-like Kinase 1 Expression as a Biomarker in Colorectal Cancer: A Retrospective Two-Center Study
Published 2024-12-01“…Further research on these combinations is necessary, as well as the discovery of new potential targets for targeted therapy and the mechanisms of synergistic effects in tumors with PLK-1 overexpression.…”
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38532
Calculation of a fibre concrete block as a part of locally reinforced truss nodes made of square hollow sections
Published 2024-05-01“…The bearing capacity of a node with the direct adjacency of struts to the chords of trusses made of S+HS is almost completely determined by geometry and physical and mechanical characteristics of truss elements made of SHS. …”
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38533
Antibacterial Potential of Endemic Medicinal Plants of the Maluku Islands, Indonesia, against Urinary Tract Infection Pathogens
Published 2024-09-01“…Further investigation is necessary to fully comprehend the mechanisms of action, detection, and description of bioactive compounds, particularly against human pathogens.…”
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38534
Influence of food availability on the diet and activity budget of two western lowland gorilla (Gorilla gorilla gorilla) groups of differing size in the Dzanga-Ndoki National Park,...
Published 2014-01-01“…We suggest that WLGs may cope with increased group size costs through other mechanisms such as group spread, rather than lowering diet quality or further changing activity patterns. …”
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38535
Morphological, Physiological, and Transcriptional Changes in <i>Crocus sativus</i> L. Under In Vitro Polyethylene Glycol-Induced Water Stress
Published 2025-01-01“…It also triggers significant changes in biochemical and molecular mechanisms, indicating the plant’s susceptibility to water scarcity.…”
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38536
Vaccarin suppresses diabetic nephropathy through <?A3B2 pi6?>inhibiting the EGFR/ERK1/2 signaling pathway
Published 2024-08-01“…Nonetheless, the potential role and mechanism of VAC in the etiology of DN have yet to be completely elucidated. …”
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38537
Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context
Published 2025-03-01“…These changes statistically mediated the association of Bacteroides salyersiae with sepsis, suggesting a potential underlying mechanism. A combined diagnostic model incorporating B.salyersia, NK cells in CD45+ leukocytes, and C-reactive protein (CRP) demonstrated high accuracy in distinguishing sepsis from non-sepsis (area under the receiver operating characteristic curve, AUC = 0.950, 95% CI: 0.811–1.000). …”
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38538
COVID-19 encephalopathy with severe neurological symptoms: a clinical case presentation with literature review
Published 2023-10-01“…However, the most likely etiology of encephalopathy is multifactorial: systemic disease response, inflammation, coagulopathy, direct viral neuroinvasion, endoartheritis, and possibly post-infectious autoimmune mechanisms. For patients with suspected changes in the level of consciousness due to coronavirus infection, it is recommended to perform a thorough examination of the cerebrospinal fluid (CSF), head imaging with a preference for magnetic resonance imaging (MRI), and electroencephalography (EEG) It is worth noting that blood or imaging tests often do not show specific changes in patients with encephalopathy. …”
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38539
Long non-coding RNA SNHG17 may function as a competitive endogenous RNA in diffuse large B-cell lymphoma progression by sponging miR-34a-5p.
Published 2023-01-01“…We investigated the functional mechanism of long non-coding small nucleolar host gene 17 (SNHG17) in diffuse large B-cell lymphoma (DLBCL). lncRNAs related to the prognosis of patients with DLBCL were screened to analyze long non-coding small nucleolar host gene 17 (SNHG17) expression in DLBCL and normal tissues, and a nomogram established for predicting DLBCL prognosis. …”
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38540
Increasing vulnerability of an endemic Mediterranean-climate conifer to changing climate and fire regime
Published 2025-01-01“…The climate and fire vulnerability of BDF could be reduced by management actions such as mechanical fuel treatments and post-fire restoration, but these are highly constrained by topography, access, and sensitive wildlife species. …”
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