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38321
Identification of Behavioral, Clinical, and Psychological Antecedents of Acute Stimulant Poisoning: Development and Implementation of a Mixed Methods Psychological Autopsy Study
Published 2025-01-01“… Abstract BackgroundDespite increasing fatal stimulant poisoning in the United States, little is understood about the mechanism of death. The psychological autopsy (PA) has long been used to distinguish the manner of death in equivocal cases, including opioid overdose, but has not been used to explicitly explore stimulant mortality. …”
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38322
Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study
Published 2025-01-01“…Neuritin, significantly expressed in injured brain tissues, is implicated in the molecular mechanisms underlying acute brain injury. We aimed to explore the prognostic and predictive value of serum neuritin in ICH.MethodsIn this prospective cohort study, serum neuritin levels were measured at admission in 202 patients, on post-ICH days 1, 3, 5, 7, and 10 in 54 of these patients, and at the time of enrollment in 100 healthy controls. …”
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38323
SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis
Published 2025-01-01“…Background: This study investigates the role of small ubiquitin-like modifier (SUMO)-specific peptidase 5 (SENP5), a key regulator of SUMOylation, in esophageal squamous cell carcinoma (ESCC), a lethal disease, and its underlying molecular mechanisms. …”
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38324
Filtration flow rate at low convection volume in continuous hemodiafiltration using cytokine adsorbing hemofilter does not affect cytokine clearance in an experimental model
Published 2025-01-01“…Two types of CAH are available, including polymethyl methacrylate (PMMA) and polyethylenimine-coated polyacrylonitrile (AN69ST), each having distinct adsorption mechanisms. PMMA adsorbs substances with hydrophobic bases through hydrophobic interactions, resulting in occlusion of the membrane pores. …”
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38325
Study of cardiovascular risk in type 2 diabetic patients in the acute phase of the coronavirus infection and post-COVID period on the background of therapy with sodium-glucose cotr...
Published 2024-12-01“…The relevance of finding optimal methods for treatment of people with type 2 diabetes (T2DM) who had coronavirus disease 2019 (COVID-19) is due to the fact that these conditions have a number of common pathogenetic mechanisms that cause complications of both diseases. …”
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38326
Synthesis and Characterization of Copper Ferrite Nanoparticles for Efficient Photocatalytic Degradation of Organic Dyes
Published 2025-01-01“…The study identified that hydroxyl radicals (·OH), generated from H2O2 decomposition under visible light irradiation, played a critical role in enhancing the efficiency of the photo-Fenton reaction. A proposed mechanism involves the excitation of CuFe2O4 under visible light, facilitating electron transfer that leads to the generation of ·OH radicals, which degrade the dye molecules. …”
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38327
In Silico Exploration of Staphylococcal Cassette Chromosome <i>mec</i> (SCC<i>mec</i>) Evolution Based on Phylogenetic Relationship of <i>ccrAB/C</i>
Published 2025-01-01“…In addition, the duplicate appearance of <i>ccrAB/C</i> and fixed composition of the <i>ccrAB/C</i> complex among different strains were indicative of more complicated transmission mechanisms than targeting direct repeats of SCC<i>mec</i>.…”
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38328
Research on Technology of Optical Switch Devices with Integrated Tunable Filters
Published 2024-12-01“…It is noted that Micro Electro Mechanical Systems (MEMS) can respectively realize the functions of OSW and TOF, and MEMS devices are relatively easy to implement with advantages such as fast tuning speed, wide tunable range, and small size. …”
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38329
Progression of ampC amplification during de novo amoxicillin resistance development in E. coli
Published 2025-02-01“…We propose that the transposon IS1 contributes to the amplification ampC region, that the sigma factor 70 regulates ampC overexpression, and that these combined form the backbone of a putative mechanism for ampC amplification.…”
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38330
The Predictive Value of Growth Differentiation Factor-15 in Recurrence of Atrial Fibrillation after Catheter Ablation
Published 2020-01-01“…The mechanisms underlying the recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFCA) are not well concerned. …”
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38331
Migration Crisis in West Africa: Limits and Prospects of Political Regulation
Published 2024-12-01“…At the same time, the ECOWAS migration policy does not contain a sufficient number of specific mechanisms for overcoming migration crises. The lack of financial and human resources in the countries of West Africa determines the high level of involvement of international organizations in the development of the migration policy of ECOWAS. …”
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38332
Association between Loa loa microfilaremia and anatomical hyposplenia in a rural area of the Republic of Congo: a population-based cross-sectional study
Published 2025-02-01“…Abstract Background Data suggest excess mortality is associated with loiasis, which is endemic to Central Africa, although the underlying mechanisms remain unknown. We hypothesized that there could be an association between Loa loa microfilarial densities (MFD) and lower spleen volume (SV) due to micro-obstruction linked to circulating microfilariae (mf). …”
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38333
Analysis of mRNA Pentatricopeptide Repeat Domain 1 as a prospective oncogene in clear cell renal cell carcinoma that accelerates tumor cells proliferation and invasion via the Akt/...
Published 2025-01-01“…PTCD1 regulated ccRCC progression via various cancer mechanisms including PI3K-Akt signaling, focal adhesion, PD-L1 expression, and PD-1 checkpoints in cancer. …”
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38334
RNA m6A involves in regulation of oxidative stress and apoptosis may via NF-kB pathway in cadmium-induced lung cells
Published 2025-01-01“…N6-methyladenosine (m6A) plays a crucial role in the development of lung tumors, but the mechanisms remain incompletely clarified. In present study, our data demonstrated that prolonged treatment of 1 μmol/L CdSO4 for 40 passages in bronchial epithelial cells (Beas-2B cells) resulted in the development of a malignant phenotype, which manifested as boosted proliferation, migration and invasion capacity as well as apoptosis reduction. …”
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38335
The expression of exosomal and cellular miRNAs in predicting oxaliplatin resistance in colorectal cancer cells: an in silico and in vitro study
Published 2025-01-01“…Therefore, it is crucial to comprehend the molecular mechanisms of oxaliplatin resistance and develop effective strategies to counter drug resistance. …”
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38336
Top 100 most-cited articles on apoptosis of non-small cell lung cancer over the past two decades: a bibliometrics analysis
Published 2025-01-01“…BackgroundRecently there has been an increasing number of studies have explored apoptosis mechanisms in lung cancer (LC). However, no researchers have conducted a bibliometric analysis of the most cited articles in this field.ObjectiveTo examine the top 100 most influential and cited publications on apoptosis in non-small cell lung cancer (NSCLC) from 2004 to 2023, summarizing research trends and key focus areas.MethodsThis study utilized the Web of Science Core Database (WOSCC) to research NSCLC apoptosis from 2004 to 2023, using keyword selection and manual screening for article searches. …”
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38337
To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation
Published 2024-01-01“…Seven biomarkers, namely, SLC37A4, ACOX2, GPD1, angiotensin-converting enzyme 2 (ACE2), SLC9A3, AGT, and PLG, were acquired via RF and RFE analyses, and they were found to be involved in various mechanisms such as glomerulus development, fatty acid metabolism, and peroxisome. …”
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38338
Assessing costs and constraints of forest residue disposal by pile burning
Published 2025-01-01“…Given the economic, human health, and climate implications of current pile burning practice, removing residues as feedstocks for carbon-negative utilizations is recommended as a near-term priority. Policy mechanisms, such as feedstock production, transport, or offtake subsidies of a similar magnitude to such avoided costs, could efficiently incentivize residue removal and support such climate-positive utilizations.…”
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38339
Association between Healthy Eating Index-2020, alternative Mediterranean Diet scores, and gastrointestinal cancer risk in NHANES 2005–2018
Published 2025-02-01“…Further research is needed to elucidate the mechanisms and effects of healthy diet management and high-quality diets in the prevention of GI cancers.…”
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38340
Structural and Thermal Properties of Ethiopian Eri and Mulberry Silk Fibres
Published 2020-01-01“…This research work aimed to study the structural, physical, mechanical, and thermal properties of Ethiopian silkworm cocoon’s filament. …”
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