Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study by Carmen Tsang, Robert Wood, Tendai Mugwagwa, Kiran K Rai, Jingyan Yang, Theo Tritton, Jennifer L Nguyen, Kathleen Michelle Andersen, Maya Reimbaeva, Leah J McGrath, Poppy Payne, Bethany Emma Backhouse, Diana Mendes, Rebecca Butfield, Kevin Naicker, Mary Araghi

“…While few (6.0%) patients in critical care required mechanical ventilation, its use was higher in older adults (50–74 years: 8.3%; <50 years: 4.3%). …”
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Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter? by Agnieszka Zelek-Molik, Anna Gądek-Michalska, Michał Wilczkowski, Adam Bielawski, Katarzyna Maziarz, Grzegorz Kreiner, Irena Nalepa

“…In the first part, rats were exposed to RS for 3, 7, or 14 days, and the expression of glutamate signaling proteins (p(S845)/t GluA1, p(Y1472)/t GluN2B, VGLUT1, and VGLUT2) in the FC was analyzed to determine the optimal RS duration for studying the mechanisms of hypofrontality. In the second part, rats were exposed to RS for 14 days, and BET (5 mg/kg, p. o.) was administered during the last 8 days immediately after RS. …”
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Improved gas separation performance of PMMA/Matrimid@5218/graphene oxide (GO) mixed matrix membranes by Amirali Salehi, Mohammadreza Omidkhah, Abtin Ebadi Amooghin, Mohammad Mehdi Moftakhari Sharifzadeh

“…In this study, we fabricated a blend membrane by incorporating Poly (5 amino-1-(4 aminophenyl)-1,3-trimethyl indane) (Matrimid@5218) into the poly(methyl methacrylate) (PMMA) polymer matrix to harness the positive properties of Matrimid, such as high mechanical strength and thermal stability, along with the suitable permeability and selectivity of PMMA. …”
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The Effect of Gender Inequality in Education on Rural Poverty in Kamuganguzi Sub-County Kabale District. by Niwamanya, Obed

“…Specifically, this study was guided by the following objectives; To find out the factors that influence gender inequality in education on rural poverty in Kamuganguzi Sub-county, Kabale District, To ascertain the impacts of gender inequality in education on rural poverty in Kamuganguzi Sub-county, Kabale District and To explore mechanisms to reduce gender inequality on rural poverty in Kamuganguzi Sub-county, Kabale District. …”
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Gender Inequality and Education Attainment by Male and Female in Higher Institutions: A Case Study of Kabale University. by Twinomujuni, Promise

“…The objectives of the study were to examine factors for gender inequality in education attainment at Kabale University, to investigate the impacts of gender inequality on education at Kabale University, and to explore mechanisms to balance gender inequality in Education at Kabale University. …”
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Role of Government Projects and Youth Employment in Kisoro District: A Case Study of Youth Livelihood Program. by Zaninka, Esther

“…The study recommends that it is of significant importance that the Ministry of Gender, labor, and Social Development develops mechanisms that will enhance youth access to YLP by scrapping business registration costs, and business licensing costs, Equally, the age bracket for registration of businesses should be flexible from 17 years to 35 years old to ensure youth are encouraged early enough to venture into entrepreneurship, and also accessing YLP.…”
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Assessing the Use of Crushed Rock Aggregate and Carbon Black for Laterite Soil Stabilization in Road Construction. by Turyamureeba, Emmanuel

“…The purpose of this research and design project was therefore to investigate the use of carbon black in the reduction of the amount of crushed rock aggregates used in the mechanical stabilization of suitable lateritic soils for road base construction. …”
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Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa by Keneth Iceland, Kasozi, Zirintunda, Gerald, Ssempijja, Fred, Buyinza, Bridget, Alzahrani, Khalid J., Matama, Kevin, Nakimbugwe, Helen N., Alkazmi, Luay, Onanyang, David, Bogere, Paul, Ochieng, Juma John, Islam, Saher, Matovu, Wycliff, Nalumenya, David Paul, Batiha, Gaber El-Saber, Osuwat, Lawrence Obado, Abdelhamid, Mahmoud, Shen, Tianren, Omadang, Leonard, Welburn, Susan Christina

“…Cyclic transmission through Glossina species occurs for T. congolense, T. simiae, T. vivax, T. brucei, and T. b. rhodesiense, T. b. gambiense, and within Reduviid bugs for T. cruzi. T. evansi is mechanically transmitted, and T. vixax is also commonly transmitted by biting flies including tsetse. …”
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Designing a defensive silence failure model of creative employees in organizations by Azam Khosravi, karam khalili, Esfandyar Mohammadi

“…Providing training on the recognition and principles of supporting employees in the face of defensive silence can also be useful.Implement supportive policies and procedures: Develop and implement policies and procedures that allow employees to break the defensive silence and report problems and deficiencies without fear of negative consequences.Designing confidential mechanisms: creating safe and confidential mechanisms to welcome employee reports and complaints, so that their personality is protected and they do not experience any negative consequences.…”
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Neuroprotective Effect of Crocin on Rats with Focal Cerebral Ischemia-Reperfusion Injury Based on TLR4/NF-κB Pathway by LI Xiaolei, ZHU Haisheng, MA Ruijuan, HU Ke, FENG Lina, WANG Xudong

“…ObjectiveTo observe the protective effect of crocin on neurons of rats with focal cerebral ischemia-reperfusion (FCIR) injury based on the toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) pathway, and to explore the possible mechanism of crocin in the prevention and treatment on FCIR injury.MethodsA total of 128 SD rats were divided randomly into sham operation group, model group, crocin group, crocin + lipopolysaccharide group, with 32 rats in each group. …”
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Effect of Electroacupuncture at Baihui and Shenting on Cognitive Function in Cerebral Ischemia-reperfusion Injured Rats by Yongmei YOU, Yijing JIANG, Zhicheng LIN, Zengtu ZHAN, Jun WANG, Wei WEI, Shanli YANG

“…Objective:To observe the effect of electroacupuncture (EA) at Baihui and Shenting on cognitive function in rats after cerebral ischmeia-reperfusion (IR) injury, and explore the possible mechanism.Methods:A total of 111 male adult SD rats weighting (300±20) g were selected and randomly divided into the sham operation group (<italic>n</italic>=36) and the operation group (<italic>n</italic>=75). …”
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MUC5B modulation of early oral biofilm glucose metabolism by Carolina Robertsson, Carolina Robertsson, Julia Davies, Gunnel Svensäter, Anders Bay Nord, Niclas Norrström, Claes Wickström

“…This suggests that MUC5B may represent an innate mechanism to regulate biofilm eubiosis by supporting early coadhesion while regulating total biomass. …”
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Comprehensive Analysis of PDLIM3 Expression Profile, Prognostic Value, and Correlations with Immune Infiltrates in Gastric Cancer by Xinpeng Hu, Minfeng Chen, Qiang Ruan, Changzheng Shi, Jinghua Pan, Liangping Luo

“…GO and KEGG analyses were performed to illuminate the molecular mechanisms of action of PDLIM3. TIMER2.0 and GEPIA were applied to investigate correlations between PDLIM3 expression and gene marker subsets signifying immune infiltration, with TIMER2.0 exploring the correlations between PDLIM3 and related signaling pathways. …”
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A temporary cholesterol-rich diet and bacterial extracellular matrix factors favor Salmonella spp. biofilm formation in the cecum by Alonso Cruz-Cruz, Megan E. Schreeg, John S. Gunn

“…A greater understanding of these mechanisms will allow the formulation of new therapeutic strategies specifically targeted at preventing typhoid fever dissemination from chronic carriers.…”
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Microscale bone interlocking enhances osseointegration strength on the rough surface of 3D-printed titanium implants: experimental and finite element analysis by Tianyu Shu, Haoyu Shi, Meng Li, Yu-Chia Lin, Ang Li, Dandan Pei

“…However, the biomechanical mechanisms underlying this enhanced osseointegration strength remain elusive, thereby impeding the standardization and broader clinical application of 3D-printed titanium implants. …”
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Role of plasminogen/plasmin system components and matrix metalloproteases in retinal artery occlusion following cardiac surgery by L.V. Natrus, N.Ia. Kovalchuk, I.S. Tanasiichuk, Iu.O. Panchenko

“…Of these, 23 patients older than 60 years who had conventional-access mechanical prosthetic valve replacement with cardiopulmonary bypass were stratified into the group of high risk (HR) for RAO. …”
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Acute administration of NLX-101, a Serotonin 1A receptor agonist, improves auditory temporal processing during development in a mouse model of Fragile X Syndrome by Xin Tao, Katilynne Croom, Adrian Newman-Tancredi, Mark Varney, Khaleel A. Razak

“…The differential effects of serotonin modulation on ERP, background power and temporal processing suggest different developmental mechanisms leading to these phenotypes. Conclusions These results suggest that NLX-101 could constitute a promising treatment option for targeting post-synaptic 5-HT1A receptors to improve auditory temporal processing, which in turn may improve speech and language function in FXS.…”
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Reduced interhemispheric connectivity in traumatic brachial plexopathies after bionic reconstruction by Galia V Anguelova, Agnes Sturma, Oskar Aszmann, Mehmet S Yildirim, Anna Boesendorfer, Victor Schmidbauer, Karl-Heinz Nenning, Gregor Kasprian

“…Patients without prosthesis also exhibited fewer structural connections between the left and right thalamus and pallidum, whereas those with prosthesis demonstrated increased structural connectivity compared to controls.The increased and more widespread cortical activity and functional connectivity after TBPL may be due to increased central effort necessary for motor execution and planning, representing a compensation mechanism for the decrease of interhemispheric and subcortical connectivity. …”
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Luteolin Pretreatment Ameliorates Myocardial Ischemia/Reperfusion Injury by lncRNA-JPX/miR-146b Axis by Tongda Xu, Yuanyuan Zhang, Gege Liao, Haochen Xuan, Jie Yin, Jieli Bao, Yang Liu, Dongye Li

“…We established the models in vitro (HL-1 cells) and in vivo (C57BL/6J mice) to certify the protection mechanism of Lut pretreatment on myocardial I/R injury. …”
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GATA1-mediated macrophage polarization via TrkB/cGMP–PKG signaling pathway to promote the development of preeclampsia by Wushan Li, Fei Hou, Di Cheng, Fengchun Gao, Jin Wang, Baoxia Cui

“…Recent studies have indicated that the transcription factor GATA1 may be implicated in the pathological processes of PE, but the underlying mechanism remains elusive. NTRK2/cGMP–PKG signaling pathway plays a crucial role in regulating the function and polarization of macrophages, which are key immune cells at the maternal–fetal interface. …”
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