The Promising Key Factors Mediating Secondary Neuronal Damage in the Perihematomal Region of Intracerebellar Hemorrhage of Mice by Saandeep Bhatia, Ramissh Paramasivam, Mohd Khairul Izamil Bin Zolkefley, Regunath Kandasamy, Sangu Muthuraju, Jafri Malin Abdullah

“…The underlying mechanisms of secondary neuronal damage following intracerebellar hemorrhage (ICbH) have not yet been clearly understood. …”
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CpG-ODN Induces a Dose-Dependent Enrichment of Immunological Niches in the Spleen and Lungs of Neonatal Chicks That Correlates with the Protective Immunity against Escherichia coli by Thushari Gunawardana, Khawaja Ashfaque Ahmed, Kalhari Goonewardene, Shelly Popowich, Shanika Kurukulasuriya, Ruwani Karunarathana, Lisanework E. Ayalew, Ashish Gupta, Betty Lockerbie, Marianna Foldvari, Suresh K. Tikoo, Philip Willson, Susantha Gomis

“…However, a causal relationship between CpG-ODN-induced immune enrichment and protective mechanisms remains unestablished. In this study, we investigated in ovo administered CpG-ODN-mediated immune cell recruitment in the immunological niches in lymphoid (spleen) and nonlymphoid (lungs) organs using various doses of CpG-ODN and examined whether the immunological profiles have any correlation with immunoprotection against E.coli infection. …”
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Analyzing sorbitol biosynthesis using a metabolic network flux model of a lichenized strain of the green microalga Diplosphaera chodatii by Hadi Nazem-Bokaee, Erik F. Y. Hom, Sarah Mathews, Cécile Gueidan

“…An important capability of the new metabolic model of D. chodatii is capturing both linear and cyclic electron flow mechanisms characterized in several other microalgae. …”
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The Roles of Skin Fibroblasts at Local Acupoints in Chrono-Acupuncture by Nannan Liu, Zhengyu Zhao, Qizhi Zhou, Xiaohong Zhang, Yu Wang, Shiqi Huang, Dingjun Cai

“…The aim of this study was to demonstrate the peripheral mechanisms of chrono-acupuncture by observing acupuncture at different time points affecting relative proteins to regulate the cytoskeleton of fibroblasts differently. …”
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Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants by Gajalakshmi Ramanathan, Yuqi Zhao, Rajat Gupta, Siri Langmo, May Bhetraratana, Fen Yin, Will Driscoll, Jerry Ricks, Allen Louie, James A. Stewart, Timothy R. Gould, Timothy V. Larson, Joel Kaufman, Michael E. Rosenfeld, Xia Yang, Jesus A. Araujo

“…Diesel exhaust (DE) emissions are important contributors which induce vascular inflammation and metabolic disturbances by unknown mechanisms. We aimed to determine molecular pathways activated by DE in the liver that could be responsible for its cardiometabolic toxicity. …”
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CDC20 and CCNB1 Overexpression as Prognostic Markers in Bladder Cancer by Hatice Sevim Nalkiran, Ilknur Biri, Ihsan Nalkiran, Hakki Uzun, Sumeyye Durur, Recep Bedir

“…Further studies with larger cohorts are needed to validate these findings and better understand the molecular mechanisms driving BC progression.…”
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MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling by Wenshuai He, Limin Zhao, Pengfei Wang, Maojia Ren, Yunfei Han

“…TNFSF4/TLR4/NF-κB pathway-related protein expressions were measured by Western blot. Molecular mechanisms were elucidated through quantitative real-time PCR, western blot analysis, and luciferase reporter assays. …”
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Spatial and Temporal Variations in 94-GHz Radar Backscatter From a Springtime Snowpack by William D. Harcourt, Duncan A. Robertson, David G. Macfarlane, Brice R. Rea, Mike R. James, Mark Diggins, Blair Fyffe

“…AVTIS2 is a tripod-mounted, real-aperture radar system which mechanically scans across a scene of interest to map normalized radar cross section <inline-formula><tex-math notation="LaTeX">$(\sigma ^{0})$</tex-math></inline-formula> and 3-D point clouds. …”
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Unraveling the Beneficial Role of Resveratrol in Fructose-Induced Non-Alcoholic Steatohepatitis with a Focus on the AMPK/Nrf2 Signaling Axis by Soha S. Zakaria, Safaa M. Hanafy

“…<i>Conclusions:</i> This study specifically examines resveratrol’s therapeutic effects in a high-fructose diet-induced NASH model, focusing on the AMPK/Nrf2 signaling pathway to address oxidative stress and autophagy, providing novel insights into its molecular mechanism of action. Resveratrol reduces NASH by boosting autophagy and activating the AMPK/Nrf2 pathway. …”
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Shi-Zhen-An-Shen Decoction, a Herbal Medicine That Reverses Cuprizone-Induced Demyelination and Behavioral Deficits in Mice Independent of the Neuregulin-1 Pathway by Chao Ma, Yan Wu, Xinyao Liu, Yi He, Yuan Jia, Pei Chen, Dongqing Yin, Yanzhe Ning, Guoqiang Xing, Zuoli Sun, Hongxiao Jia

“…Shi-Zhen-An-Shen decoction (SZASD), a Chinese herbal medicine that is a liquor extracted from plants by boiling, has been reported to be effective in treating schizophrenia. However, the mechanism is unclear. Abnormal demyelination has been implicated in schizophrenia. …”
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Biotechnological Effects of <i>Lactobacillus plantarum</i>, Cellulase, and Xylanase on Nutritional Quality and Microbial Community Structure of Corn Stover Silage by Jianliang Liu, Mingjian Liu, Panjie Sheng, Chaoran Song, Weiqin Ma, Baochao Bai, Jiayu Zhao, Shuai Du, Gentu Ge, Zhijun Wang, Yushan Jia

“…Specifically, <i>Lactobacillus plantarum</i>, cellulase preparations (commercial cellulase enzyme preparations), and xylanase preparations (commercial xylanase enzyme preparations) were employed as additives to investigate their synergistic effects and underlying mechanisms during the silage process. Furthermore, dosage gradients were established to determine the optimal dosage range, providing a robust scientific basis for the optimization of additive applications. …”
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Preliminary evidence of immune infiltration and neutrophil degranulation in peripheral blood of non-obese OSA patients related to cognitive decline by Qingqing Liu, Yanru Ou, Ting Liu, Yuming He, Xiangming Quan, Ruoyun Ouyang, Zhihui Shi

“…Abstract Obstructive sleep apnea (OSA) patients have varying degrees of cognitive impairment, but the specific pathogenic mechanism is still unclear. Meanwhile, poor compliance with continuous positive airway pressure (CPAP) in OSA prompts better solutions. …”
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The impact of arbuscular mycorrhizal colonization on flooding response of Medicago truncatula by Vajiheh Safavi-Rizi, Vajiheh Safavi-Rizi, Helen Friedlein, Sayedhamid Safavi-Rizi, Franziska Krajinski-Barth

“…Future research will focus on understanding the molecular mechanisms behind AMF modulation of flooding stress responses, including nutrient uptake and metabolism, stress tolerance, and recovery post-flooding. …”
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Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max) by Jinyu Zhang, Liying Zou, Li Wang, Dongchao Zhang, Ao Shen, Yongqi Lei, Maoni Chao, Xinjuan Xu, Zhiwei Xue, Zhongwen Huang

“…Notably, 12 GmSec14 genes exhibited significant alterations in expression following salt or drought stress, suggesting a potential role for these genes in stress response mechanisms. Furthermore, the protein interaction network and miRNA regulation associated with GmSec14s were predicted to elucidate the potential functions of GmSec14 members. …”
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Sign Problem in Tensor-Network Contraction by Jielun Chen, Jiaqing Jiang, Dominik Hangleiter, Norbert Schuch

“…To provide insight into this early breakdown of computational hardness and the accompanying entanglement transition, we construct an effective classical statistical-mechanical model that predicts a transition at a bias of the tensor entries of 1/D, confirming our observations. …”
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Adolescent Psychological Assistance Treatment Strategy Integrating Home-School Coordination and Network Information by Yaling Li

“…Based on this, this paper will focus on optimizing the home-school cooperation strategy, further clarify the main responsibilities of the school, teachers, and parents in the home-school cooperation education in the strategy, establish and improve the home-school cooperation mechanism based on this, and focus on the cultivation of parents’ mental health education and teachers’ mental health guidance professional skills in this process. …”
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Role of Cerebellum in the Treatment of Dystonia and Application of Cerebellum Transcranial Magnetic Stimulation by WENG Yajing, WU Yi, LIU Gang, CHENG Huilan, XIE Hongyu, TIAN Shan

“…Existing animal studies suggested that the cerebellum affects dystonia through at least three mechanisms: 1) abnormal cerebellar efferent signal patterns; 2) abnormal connections between the cerebellum and basal ganglia nuclei; 3) abnormalities in the shape or structure of cerebellar cells. …”
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Longitudinal Changes of Sensorimotor Resting-State Functional Connectivity Differentiate between Patients with Thalamic Infarction and Pontine Infarction by Peipei Wang, Zhenxiang Zang, Miao Zhang, Yanxiang Cao, Zhilian Zhao, Yi Shan, Qingfeng Ma, Jie Lu

“…The different patterns of sensorimotor functional damage and reorganization in patients with pontine infarction and thalamic infarction may provide insights into the neural mechanisms underlying functional recovery after stroke.…”
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Effects of dietary Acremonium terricola culture on production performance, serum biochemical parameters, egg quality and yolk amino acid contents of Beijing You-chicken by Jianzhong Wang, Cun Liu, Xiaowei Gong, Yanhan Liu

“…Future studies should focus on optimizing ATC dosage and exploring its underlying mechanisms for enhanced poultry production.…”
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Effects of different monochromatic light on growth performance and liver circadian rhythm of Yangzhou geese by Yingqing Xu, Yi Tang, Yiyi Cheng, Wen Yang, Jie Liu, Binbin Guo, Gang Luo, Huanxi Zhu

“…However, monochromatic light significantly down-regulated the gene expression, peak and amplitude of retinoic acid receptor-related orphan receptor α (RORα), as well as advancing or delaying the phase of the circadian rhythm. …”
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