Activin A promoted the anti‐tumor effect of ActRIIA high CD8+ T cells in mouse hepatoma by Liangchang Hu, Yu Zhao, Xuguang Zhang, Chunhui Ma

“…The purpose of this study is to investigate the regulatory effect and related mechanisms of activin A on CD8+ T cells. Methods This study established a mouse subcutaneous transplantation model of hepatoma to explore whether activin A has a regulatory effect of CD8+ T cells. …”
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First-principles calculations to investigate thermoelectric, thermophysical, and optical properties of RNi₄P₁₂ (R = Sm, Eu) rare-earth metal skutterudites by Poorva Nayak, Dinesh C. Gupta

“…Structural, phonon stability, mechanical, electronic, magnetic, transport, thermal, and optical properties are thoroughly explored to provide a holistic understanding of these materials. …”
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Project ChemicalBlooms: Collaborating with citizen scientists to survey the chemical diversity and phylogenetic distribution of plant epicuticular wax blooms by Le Thanh Dien Nguyen, Nicole Groth, Kylie Mondloch, Edgar B. Cahoon, Keith Jones, Lucas Busta

“…Thus, our data suggest that a lineage‐specific mechanism other than biosynthesis exists that enables select species to generate triterpenoid‐rich surface wax crystals. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

“…In this study, we explored the roles of S100A8/A9 in modulating neuroinflammation and influencing TBI outcomes, delving into the underlying mechanisms. S100A8/A9-enriched neutrophils were present in the injured brain tissue of TBI patients, and elevated plasma levels of S100A8/A9 were correlated with poorer neurological function. …”
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The Effect of Concussion History on Lower Extremity Injury Risk in College Athletes: A Systematic Review and Meta-Analysis by Vanessa Ramirez, Ryan McCann, Eric Schussler, Jessica Martinez

“…Further research is needed to investigate the mechanism behind this increased risk. Clinical assessments throughout the concussion return-to-play protocol may need to be improved in order to detect lingering impairments caused by concussions…”
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Gengnianchun Recipe Protects Ovarian Reserve of Rats Treated by 4-Vinylcyclohexene Diepoxide via the AKT Pathway by Fangui Zhao, Wenjun Wang

“…Here we aim to examine the effect of GNC in a DOR rat model induced by 4-vinylcyclohexene diepoxide (VCD), a chemical that selectively destroys ovarian small preantral follicles, and further investigate the possible mechanisms. Female SD rats were randomly divided into four groups: control group (C), model group (M), high-dose GNC group (H), and low-dose GNC group (L). …”
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Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition. by Tiffany M Halvorsen, Kaitlin A Schroeder, Allison M Jones, Disa Hammarlöf, David A Low, Sanna Koskiniemi, Christopher S Hayes

“…The specificity of this protein interaction network provides a mechanism for self/nonself discrimination between E. coli isolates.…”
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Association between serum carotenoids levels and severe headache or migraine in adults: a cross-sectional study from NHANES by Tian Hu, Yufei Chen, Siyu Chen, Rui Xue

“…This evidence indicates that carotenoids may provide a protective effect against migraines; however, further investigation is warranted to substantiate these associations and to elucidate the underlying mechanisms.…”
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Enhancing work environments and reducing turnover intention: a multicenter longitudinal cohort study on differentiated nursing practices in Dutch hospitals by Julia van Kraaij, Neeltje de Vries, Hanna Wessel, Hester Vermeulen, Catharina van Oostveen, RN2Blend Consortium

“…Future research should include longer term studies to fully understand the complex relationship and accompanying mechanisms between differentiated nursing practices, the nursing work environment, and turnover intention. …”
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Infeksi Cacing dan Alergi by Selfi Renita Rusdji

“…Hygiene hypothesis is a theory that can explain this phenomen. The mechanisms are mast cell saturation, IgG4 blocking and modified Th2.…”
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Green Apple Detection Method Based on Multidimensional Feature Extraction Network Model and Transformer Module by Wei Ji, Kelong Zhai, Bo Xu, Jiawen Wu

“…At the same time, in order to solve the problems of slow convergence speed and large calculation amount of the basic network model, the convergence speed of the overall network model is improved by replacing the attention mechanism of Transformer. Experimental results show that compared with the original DETR model, the proposed algorithm has improved in AP, AP50, and AP75 indicators, especially in the AP50 indicator, which has the most obvious improvement reaching a detection accuracy of 97.12%. …”
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Association of Pathology Markers with Somatostatin Analogue Responsiveness in Acromegaly by George Kontogeorgos, Vyron Markussis, Eleni Thodou, Efi Kyrodimou, Theodossia Choreftaki, Panagiotis Nomikos, Kostas I. Lampropoulos, Stylianos Tsagarakis

“…These findings improve our understanding of the mechanisms underlying SA response to medical treatment.…”
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Physical and emotional abuse with internet addiction and anxiety as a mediator and physical activity as a moderator by Jinyin Peng, Yang Liu, Xubo Wang, Zhenxiu Yi, Lei Xu, Fulan Zhang

“…Anxiety may be the internal mechanism of physical-emotional abuse affecting university students’ Internet addiction, and physical activity plays a moderator role in the relationship between physical-emotional abuse and university students’ Internet addiction. …”
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<i>In silico</i> mapping of coronary artery disease genes by I. V. Zorkoltseva, N. M. Belonogova, G. R. Svishcheva, A. V. Kirichenko, T. I. Axenovich

“…However, the genetic mechanisms and specific genes controlling this disease are still not fully understood. …”
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Protective Effect of Bergapten against Human Erythrocyte Hemolysis and Protein Denaturation In Vitro by Douglas Bosco Aidoo, Daniels Konja, Isaac Tabiri Henneh, Martins Ekor

“…The ability of bergapten to inhibit protein denaturation was studied as part of an investigation on its mechanism of action. The results showed a significant concentration-dependent reduction in protein denaturation. …”
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Investigating the Relationships between Internet Addiction and Suicidal Ideation in Adolescent Girls by Zeynab Akbari, Fatemeh Serjouie, Jafar Sarani Yaztappeh, Mohammad Hossein Turkzadeh, Faeze Ziaei, Ali Bagheri, Maryam Sate Zohd, Amir Sam Kianimoghadam

“…Using these findings, we can elucidate the mechanism of how IA affects individual SI, providing critical information for the development and implementation of targeted strategies and interventions to reduce SI among Iranian adolescent girls. …”
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Differences in clinical characteristics between coronavirus disease 2019 (COVID-19) and influenza: a systematic review and meta-analysis by Yingying Han, Jia Guo, Xingzhao Li, Zhuan Zhong

“…Patients with COVID-19 had longer stays in the hospital (MD = 3.20, 95% CI: 2.58–3.82) and ICU (MD = 3.10, 95% CI: 1.44–4.76), required mechanical ventilation more frequently (OR = 2.30, 95% CI: 1.77–3.00), and had higher mortality (OR = 2.22, 95% CI: 1.93–2.55). …”
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The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells by Chien-Ting Lin, Shang-Ju Wu, Cheng Hao Liao, Reyhung Roc Weng, Chun-Ming Lin

“…To stimulate both innate and adaptive mechanisms, we created a bifunctional eCD16A/anti-CD3-BFP adapter protein for combined use with clinically approved monoclonal IgG1 antibodies. …”
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Comparative study of phenotypic and genotypic expression of virulence factors in colonizing and pathogenic carbapenem resistant Acinetobacter baumannii (CRAB) by Swati Sharma, Kamal Singh, Ashish Chaurasiya, Tuhina Banerjee, Royana Singh, Ghanshyam Yadav, Ashok Kumar

“…Biofilm formation, porins, micronutrient capturing mechanism and quorum sensing, provide protection against desiccation, host-pathogen killing and enhance its persistence. …”
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An untargeted metabolomic analysis of acute AFB1 treatment in liver, breast, and lung cells. by Heidi H Cao, Sabrina Molina, Susan Sumner, Blake R Rushing

“…AFB1 is synthesized by Aspergillus flavus and is known to widely contaminate foodstuffs, particularly maize, wheat, and groundnuts. The mechanism in which AFB1 causes genetic mutations has been well studied, however its metabolomic effects remained largely unknown. …”
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