Neuronal density in the brain cortex and hippocampus in Clsnt2-KO mouse strain modeling autistic spectrum disorder by I. N. Rozhkova, S. V. Okotrub, E. Yu. Brusentsev, E. E. Uldanova, E. А. Chuyko, T. V. Lipina, T. G. Amstislavskaya, S. Ya. Amstislavsky

“…Autistic spectrum disorders (ASD) represent conditions starting in childhood, which are characterized by difficulties with social interaction and communication, as well as non-typical and stereotyping models of behavior. The mechanisms and the origin of these disorders are not yet understood and thus far there is a lack of prophylactic measures for these disorders. …”
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Luteolin Regulates the Differentiation of Regulatory T Cells and Activates IL-10-Dependent Macrophage Polarization against Acute Lung Injury by Ke Xie, Yu-sen Chai, Shi-hui Lin, Fang Xu, Chuan-jiang Wang

“…Luteolin-induced Treg differentiation from naïve CD4+ T cells may be a potential mechanism for regulating IL-10 production.…”
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Antiganglioside Antibodies and Inflammatory Response in Cutaneous Melanoma by Corina Daniela Ene, Mircea Tampa, Ilinca Nicolae, Cristina Iulia Mitran, Madalina Irina Mitran, Clara Matei, Ana Caruntu, Constantin Caruntu, Simona Roxana Georgescu

“…The host’s ability to elaborate an early antiganglioside response could be considered as a defence mechanism, directed toward eliminating a danger signal from the tumour microenvironment. …”
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Single-cell sequencing analysis reveals cancer-associated pericyte subgroup in esophageal squamous cell carcinoma to predict prognosis by Kai Xiong, Bing Pan, Hao Fang, Ziyou Tao

“…BackgroundThe role of cancer-associated pericytes (CAPs) in tumor microenvironment (TME) suggests that they are potential targets for cancer treatment. The mechanism of CAP heterogeneity in esophageal squamous cell carcinoma (ESCC) remains unclear, which has limited the development of treatments for tumors through CAPs. …”
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Gawe Rapah sebagai Model Resolusi Konflik Berbasis Kearifan Lokal di Pulau Seribu Masjid, Lombok by Mohammad Zaenul Kamar, Casmini Casmini, Nurus Sa'adah

“…This study underscores the relevance of the “gawe rapah” tradition as a conflict resolution mechanism rooted in local wisdom and highlights its potential to serve as an inclusive and sustainable model for conflict resolution in other multicultural contexts. …”
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NEAT1 regulates BMSCs aging through disruption of FGF2 nuclear transport by Zifei Wang, Wenyu Zhen, Qing Wang, Yuqiang Sun, Siyu Jin, Sensen Yu, Xing Wu, Wenhao Zhang, Yulong Zhang, Fei Xu, Rui Wang, Yuxuan Xie, Wansu Sun, Jianguang Xu, Hengguo Zhang

“…LncRNA NEAT1 is considered as a proliferative inhibitory role during cellular senescence, but the relevant mechanisms remain insufficient. This study aims to elucidate how NEAT1 regulates mitotic proteins during BMSCs aging. …”
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Caracterización morfológica de agregados para concreto mediante el análisis de imágenes Morphological characterization of concrete aggregates by means of image analysis by Maria Patricia León, Fernando Ramírez

“…In this study, the morphological characteristics of coarse aggregates from two different sources are determined using both, conventional methods and image analysis by means of Fourier descriptors. Mechanical properties of concrete prepared with coarse aggregates having different elongation indexes were evaluated. …”
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Inpatient service utilization amongst infants diagnosed with Respiratory Syncytial Virus infection (RSV) in the United States. by Jason R Gantenberg, Kathryn D Thompson, Robertus van Aalst, David M Smith, Megan Richards, Christopher B Nelson, William V La Via, Sandra S Chaves, Angela M Bengtson, David A Savitz, Andrew R Zullo

“…Outcomes included extracorporeal membrane oxygenation, supplemental oxygen use (in-hospital and post-discharge), mechanical ventilation (invasive and non-invasive), chest imaging, infant mortality, length of inpatient stay, intensive care unit (ICU) admission, and number of days in the ICU.…”
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Gender-transformative HIV and SRHR programme approaches for adolescents and young people: a realist review to inform policy and programmes by Isolde Birdthistle, Annabelle Gourlay, Sagri Singh, Damilola Walker, Migena Mata

“…We sought evidence of approaches to promote sexual and reproductive health (SRH) outcomes by addressing gender transformation and removing structural barriers that broadly limit prospects for adolescents and young people.Methods We conducted a realist review to identify HIV and SRH-focused interventions with gender transformative mechanisms. Eligible interventions sought to achieve HIV/STI prevention, sexual behaviour or pregnancy outcomes among young people by enhancing agency, resources and social norms supportive of gender transformation. …”
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A Personalised Optimising Level Adaptation (OLA) Difficulty Algorithm for Scenario Simulations in Professional VR Simulators by Marcin Wolański Robert, Karol Jędrasiak

“…The algorithm’s efficacy was tested across three proprietary VR simulators covering diverse professional scenarios: public speaking, hydrogen electrolysis and mechanical technician operations. Each scenario was divided into ten blocks of varying difficulty (easy, medium, difficult), dynamically adjusted based on the user's performance. …”
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Studying Alzheimer’s disease through an integrative serum metabolomic and lipoproteomic approach by Alessia Vignoli, Giovanni Bellomo, Federico Paolini Paoletti, Claudio Luchinat, Leonardo Tenori, Lucilla Parnetti

“…The great variability in disease evolution and the incomplete understanding of the molecular mechanisms underlying AD make it difficult to predict when a patient will convert from prodromal stage to dementia. …”
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Associations between autistic traits and early ear and upper respiratory signs: a prospective observational study of the Avon Longitudinal Study of Parents and Children (ALSPAC) ge... by Amanda Hall, Dheeraj Rai, Jean Golding, Yasmin Iles-Caven, Steven Gregory, Richard Maw

“…Results suggest the need for identification and management of ear, nose and throat conditions in autistic children and may provide possible indicators of causal mechanisms.…”
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Patient and public involvement in the co-design and assessment of unobtrusive sensing technologies for care at home: a user-centric design approach by Jenny Sharma, Nazia Gillani, Imran Saied, Aaesha Alzaabi, Tughrul Arslan

“…Suggestions for refining the prototypes included adding functionality for detecting deviations in daily routines and integrating feedback mechanisms for caregivers. Conclusions Involving diverse stakeholders from the early stages of technology development enhanced the relevance and acceptability of unobtrusive sensing solutions. …”
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Thermal-Moisture Dynamics at Different Underlying Surfaces in Permafrost Regions of the Central Tibetan Plateau by considering the Effect of Rainfall by Bingbing Lei, Bin Wang, Mingli Zhang, Zhixiong Zhou, Guang Li, Guodong Yue

“…., natural ground, asphalt pavement, and gravel pavement) were selected to compare the differences in energy balance at the ground surface, water-energy transport process, and coupling mechanism in active layers under rainfall conditions by a coupled water vapor-heat model of the unsaturated frozen soil. …”
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Early childhood deprivation and the impact of negative life events on mental health in later life: a test of the stress sensitization hypothesis by Jala Rizeq, Mark Kennedy, Kirellos Miseih, Wangjingyi Liao, Edmund J. S. Sonuga-Barke

“…We discuss possible mechanisms by which difficulties in peer relations might influence the emergence of depression and anxiety to already vulnerable individuals.…”
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Gawe Rapah sebagai Model Resolusi Konflik Berbasis Kearifan Lokal di Pulau Seribu Masjid, Lombok by Mohammad Zaenul Kamar, Casmini Casmini, Nurus Sa'adah

“…This study underscores the relevance of the “gawe rapah” tradition as a conflict resolution mechanism rooted in local wisdom and highlights its potential to serve as an inclusive and sustainable model for conflict resolution in other multicultural contexts. …”
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Solanum virginianum mediated green nanoparticles to control dental pathogens by Samrin Barkath Akbar Basha, Ranjani Soundhararajan, Hemalatha Srinivasan

“…Based on exploring the mechanism of action of nanoparticles it was observed that SVAgNPs targets dental pathogens more effectively than the antibiotics by inducing the leakage of cellular macromolecules and causing oxidative stress to the bacterial cells. …”
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Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study by Isabel Omaña-Guzmán, Ashuin Kammar-García, Luis Miguel Gutierrez-Robledo, Oscar Rosas-Carrasco

“…On the other hand, obesity has been associated with osteosarcopenia, and several biological mechanisms in the relationship between muscle, bone, and fat have been identified. …”
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Both light and soil moisture affect the rhizosphere microecology in two oak species by Jinshuo Lian, Keke Cai, Aijing Yin, Yuan Yuan, Xinna Zhang, Chengyang Xu

“…Understanding the mechanisms by which seedlings respond to light and water regulation, as well as studying the response of rhizosphere microecology to drought stress, are crucial for forest ecosystem management and ecological restoration. …”
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Neurological syndromes associated with COVID-19: a multicenter study in Brazil by Aline de Moura Brasil Matos, Andre Borges Ferreira Gomes, Fernanda Martins Maia Carvalho, Francisco Tomaz Meneses de Oliveira, Lohana Santana Almeida da Silva, Flavia Esper Dahy, Joao Victor Luisi de Moura, Marcela Vieira Freire, Jose Ernesto Vidal, Rosa Maria Nascimento Marcusso, Jerusa Smid, Victor Rebelo Procaci, Rodrigo Meireles Massaud, Felipe Von Glehn, Jorge Casseb, Camila Malta Romano, Augusto Cesar Penalva de Oliveira, on behalf of NeurocovBR study group

“…The median time from COVID-19 to onset of neurological symptoms was 14 days, suggesting a post-infectious immune-mediated mechanism. Patients were 10 times more likely to die (χ2 (1) = 356.55, p < 0.01, OR = 10.89) and 38 times more likely to be hospitalized than other COVID-19 patients (χ2 (1) = 1167.9, p < 0.01, OR = 38.22). …”
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