The impact of induced stress on reactive and proactive control in depression by Akihiro Masuyama

“…Background Depression, a widespread mental health issue, is often marked by impaired cognitive control, particularly in managing proactive and reactive processes. The Dual Mechanisms of Control (DMC) framework differentiates between these two modes of cognitive control: proactive control involves sustained goal maintenance, while reactive control is more stimulus-driven and transient. …”
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Real-World Parkinson’s Hand Tremor Detection Using Ensemble Learning Techniques by Sungwook Hur, Jieming Zhang, Moon-Hyun Kim, Tai-Myoung Chung

“…Our method first applies a dynamic scanning mechanism to screen out valid walking fragments from whole walking sequence. …”
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Simulation of discrete control systems with parallelism of behavior by D. I. Cheremisinov, L. D. Cheremisinova

“…The key concepts of the TLM model for simulating the descriptions of control algorithms in the PRALU language are defined: data structure, transactions, processes, and a barrier mechanism for synchronization of parallel processes. …”
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Comprehensive analysis of metabolomics and transcriptomics reveals varied tepal pigmentation across Gloriosa varieties by Yue Sun, Pinli Hu, Yanan Jiang, Zhenzhen Wang, Jiaxing Chang, Yiwei Zhou, Haojing Shao

“…This research provides new insights into the mechanisms underlying the formation of diverse floral colors in Gloriosa tepals.…”
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Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model by Xing Tu, Zixing Zou, Jiahui Li, Simiao Zeng, Zhengchao Luo, Gen Li, Yuanxu Gao, Kang Zhang, Jing Ni

“…However, the current understanding of the targeting agents and mechanisms of RIPK3 in the treatment of glaucoma remains limited. …”
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Momordica Charantia Polysaccharides Attenuates MPP+-Induced Injury in Parkinson’s Disease Mice and Cell Models by Regulating TLR4/MyD88/NF-κB Pathway by Dengjun Guo, Jie Zhou, Meng Zhang, Reyisha Taximaimaiti, Xiaoping Wang, Hai Wang

“…To investigate the potential role of Momordica charantia polysaccharides (MCPs) in Parkinson’s disease (PD) and reveal the molecular mechanism of its function. Method. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium (1-methyl-4-phenylpyridinium, MPP+) were used to establish PD mice and cell models. …”
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Bisphenol S exposure interrupted human embryonic stem cell derived cardiomyocytes differentiation through ER-NF-κB/ERK signaling pathway by Yongru Zhou, Lin Tian, Liang Wang, Wenjing Wu, Baofang Liang, Wei Xiong, Lishi Zhang, Xiaomeng Li, Jinyao Chen

“…To explore the effect of BPS on cardiomyocyte differentiation and its mechanism, our study established the human embryonic stem cell-cardiomyocyte differentiation model (hESC-CM), which was divided into early period of differentiation (DP1:1–8d), anaphase period of differentiation (DP2:9–16d) and whole stage of differentiation (DP3:1–16d) exposed to human-related levels of BPS. …”
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RETRACTED ARTICLE: LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells by Ziyi Zhao, Yingwei Sun, Jing Tang, Yuting Yang, Xiaochao Xu

“…However, the exact role and mechanisms by which LRPPRC acts in osteosarcoma and osteosarcoma-derived cancer stem-like cells (CSCs), which potentially critically contribute to recurrence, metastasis and chemoresistance, are still largely unclear. …”
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Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway by Xiaoping Yu, Xiaolong Song, Jiali Yan, Ziting Xiong, Lujie Zheng, Yan Luo, Fengcheng Deng, Yanfeng Zhu

“…Objective: This study investigates the effects of Dp on TNBC and aims to elucidate its specific mechanisms of action. Design: We utilized cell counting kit-8 (CCK-8) assays, colony formation assays, and scratch assays to evaluate the influence of Dp on the proliferation and migration of TNBC cells. …”
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Anti malicious KGC certificateless signature scheme based on blockchain and domestic cryptographic SM9 by Fei TANG, Ning GAN, Xianggui YANG, Jinyang WANG

“…The certificateless cryptosystem can solve the problems of certificate management and key escrow at the same time, but its security model always assumes that Type II adversary (named malicious KGC) will not launch public key replacement attacks.This security assumption has certain limitations in real-world applications.As an efficient identity-based cryptographic scheme, SM9 signature scheme adopts R-ate bilinear pairing which has good security and high computational efficiency.However, it requires KGC to generate and manage keys for users, so it has the problem of key escrow.In view of the above problems, a certificateless signature scheme against malicious KGC was constructed based on blockchain and SM9 signature algorithm.Based on the properties of decentralization and tamper-proof of blockchain, the proposed scheme used the smart contract to record part of the public key corresponding to the user’s secret value on the blockchain.Then, the verifier can revoke the smart contract to query the user’s public key during the signature verification stage.Therefore, the proposed scheme ensured the authenticity of the user’s public key.The user’s private key consisted of the partial private key generated by KGC and a secret randomly chosen by the user.The user required the partial private key generated by KGC to endorse his identity identifier when the user generates the private key for the first time.Subsequently, the private key can be independently updated by changing the secret and the corresponding partial public key.During this process, the identity remains unchanged, which provided a viable solution for key management in decentralized application scenarios.The blockchain relied on the consensus mechanism to ensure the consistency of the distributed data.Based on the traceability of the blockchain, the change log of user’s partial public key was stored in the blockchain, which can trace the source of malicious public key replacement attacks and thereby prevent malicious KGC from launching public key replacement attacks.According to the experimental simulation and security proof results, the total overhead of signature and verification of the proposed scheme is only 7.4ms.Compared with similar certificateless signature schemes, the proposed scheme can effectively resist public key replacement attacks and has higher computational efficiency.…”
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How does individualised physiotherapy work for people with low back pain? A Bayesian Network analysis using randomised controlled trial data. by Bernard X W Liew, Jon J Ford, Marco Scutari, Andrew J Hahne

“…The current study cannot rule out that unmeasured mechanisms (such as tissue healing or reduced inflammation) may mediate the relationship between individualised physiotherapy treatment and improvement in disability. …”
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Timely short-term specialised palliative home care for older people with frailty and their family: a mixed-methods pilot randomised controlled trial and process evaluation by Lieve Van den Block, Kim de Nooijer, Lara Pivodic, Peter Pype, Nele Van Den Noortgate, Rose Miranda, Kim Eecloo, Stefanie De Buyser, Aurelie Joos, Katlijn Van Mulders

“…Objective The primary study aims were to evaluate the implementation, mechanisms and context of a timely short-term specialised palliative care intervention for older people with frailty (Frailty+ intervention) as well as to assess the feasibility of a randomised controlled trial to evaluate Frailty+. …”
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Pulsed alternating wavelength system lighting does not negatively impact production or welfare but reduces dopamine activity and may improve bone growth in grow-out Pekin ducks by S. Tonissen, B.J. Emmert, J.M. Schober, E.M. Oluwagbenga, D.M. Karcher, G.S. Fraley

“…At 29 DOA, the PAWS humeri were wider than controls (P = 0.025) and had increased geometrical bone mechanical properties (P < 0.003), but no differences in breaking stress were evident. …”
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Tofogliflozin attenuates renal lipid deposition and inflammation via PPARα upregulation mediated by miR-21a impairment in diet-induced steatohepatitic mice by Sae Nishihara, Masahiro Koseki, Katsunao Tanaka, Takashi Omatsu, Ayami Saga, Hiroshi Sawabe, Hiroyasu Inui, Takeshi Okada, Tohru Ohama, Daisuke Okuzaki, Yoshihiro Kamada, Masafumi Ono, Makoto Nishida, Mikio Watanabe, Yasushi Sakata

“…However, the molecular mechanism in the kidneys in this model remains unclear. …”
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CST2 promotes cell proliferation and regulates cell cycle by activating Wnt-β-catenin signalling pathway in serous ovarian cancer by Xiaohua Wang, Sufen Zhao, Yanwei Guo, Chunhui Wang, Shuyu Han, Xingcha Wang

“…Therefore, we aimed to investigate the expression levels, survival outcomes, immune cell infiltration, proliferation, cell cycle, and underlying molecular mechanisms associated with the CST2 signature in SOC.Methods The Cancer Genome Atlas database was used to acquire clinical information and CST2 expression profiles from patients with SOC. …”
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Characterization of demethylating DNA glycosylase ROS1 from Nicotiana tabacum L. by D. V. Petrova, N. V. Permyakova, I. R. Grin, D. O. Zharkov

“…One of the main mechanisms of epigenetic regulation in higher eukaryotes is based on the methylation of cytosine at the C5 position with the formation of 5-methylcytosine (mC), which is further recognized by regulatory proteins. …”
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Evolution of Legal Consolidation of Language Policy of Russian Empire on Ukrainian Provinces in XIX – early XX Century by O. V. Shevchenko

“…The need to create an effective mechanism to ensure the implementation of language policy by our state has been increased at the present stage of the development of Ukraine and its legal system. …”
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Cancellation of a preventive measure in the form of detention under martial law in the context of Art. 616 of the CPC of Ukraine by A. H. Harkusha

“…The essence of the procedure for canceling and changing a preventive measure in the form of detention under martial law has been revealed, namely, it has been clarified that this process is complex and contradictory, as there is no clear mechanism for its practical application. The deployment of military aggression by the Russian Federation against Ukraine in the legal field became a determinant of numerous changes to the current legal acts, in particular the Criminal Code of Ukraine. …”
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Metabolic Effects of Testosterone Hormone Therapy in Normal and Orchiectomized Male Rats: From Indirect Calorimetry to Lipolytic Enzymes by Mahmoud Mustafa Ali Abulmeaty, Ali Madi Almajwal, Mohamed Farouk ElSadek, Mohamed Y Berika, Suhail Razak

“…T administration in orchiectomized rats significantly increased orexigenic mediators such as ghrelin and insulin without inducing any significant changes in wt. The mechanism for this finding might be the increased TEE and the stimulation of lipolysis through the ATGL enzyme. …”
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Association between glyphosate exposure and cardiovascular health using “Life’s Essential 8” metrics in US adults by Yuankang Zhu, Zhenlin Yang, Yuhao Chen, Lingzi Qian, Changning Hao, Liangshi Hao, Boshen Yang, Junli Duan

“…Further studies are required to investigate the safe threshold and underlying mechanism of glyphosate impairment.…”
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