Side Friction of Rock-Socketed Piles Involving Thick Sediment by Tie Hang Wang, Liang Zhang, Yan Zhou Hao, Xin Jin

“…Due to the thick layer of sediment, the axial force of the rock-socketed segment of the pile gradually decreases along the vertical direction from the applied load on the pile top to zero at the bottom. According to the mechanical properties at different shear stages, a function is derived for the complete constitutive model for a pile-rock interface. …”
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Accumulation of advanced oxidation protein products aggravates bone-fat imbalance during skeletal aging by Yu-Sheng Huang, Jia-Wen Gao, Rui-Feng Ao, Xin-Yu Liu, Di-Zheng Wu, Jun-Long Huang, Chen Tu, Jing-Shen Zhuang, Si-Yuan Zhu, Zhao-Ming Zhong

“…Conclusion: Our findings revealed the involvement of AOPPs in age‐related switch between osteogenic and adipogenic differentiation, and illuminated a novel potential mechanism underlying bone-fat imbalance during skeletal aging. …”
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Emergency volunteering willingness and participation: a cross-sectional survey of residents in northern China by Hong Sun, Chaojie Liu, Wei Xu, Ye Li, Qunhong Wu, Lijun Gao, Zheng Kang, Yanhua Hao, Ning Ning, Mingli Jiao, Libo Liang, Yu Cui, Mengli Shi, Chao Liang, Xiaowen Zhao, Jie Fei, Qiuyu Wei, Ming Yi

“…This can be done through improving policies, regulations, coordination mechanisms and volunteer training and support.…”
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Physalis Calyx seu Fructus relieves chicken intestinal damage to heat via improving the antioxidant ability by Bin Yin, Changning Juan, Rongling Zhang, Shifa Yang, Haiting Wang, Yueyue Liu, Shikai Song, Zunxiang Yan, Yunpeng Yi, Zengcheng Zhao, Zhongli Huang, Shuqian Lin

“…The purpose of this study was based on the antioxidant and anti-inflammatory activities of Physalis Calyx seu Fructus (Jin Deng Long, JDL) to investigate its efficacy and mechanism in relieving chicken heat stress damage. …”
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Effect of three different intracanal medications on canal wall cleanliness and radicular dentin microhardness by Amira Ibrahim Mohamed, Soha Adel Abdou, Yousra Aly

“…All root canals were mechanically prepared. The specimens were randomly divided into three groups (each = 10) according to the type of medication used. …”
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Developmental dysfunction in a preclinical model of Kcnq2 developmental and epileptic encephalopathy by Miaomiao Mao, Nikola Jancovski, Yafit Kushner, Lucas Teasdale, Phan Truong, Kun Zhou, Samuel Reid, Linghan Jia, Ye Htet Aung, Melody Li, Christopher A. Reid, Sean Byars, Ingrid Scheffer, Steven Petrou, Snezana Maljevic

“…Conclusions: Our study reports on a novel Kcnq2 DEE mouse model recapitulating aspects of the disease phenotype with the electrophysiological and transcriptome analysis providing insights into KCNQ2 DEE mechanisms that can be leveraged for future therapy development.…”
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Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review by Giulia Negro, Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Andrea Magi, Ildebrando Marco Appollonio, Ildebrando Marco Appollonio, Alfredo Costa, Alfredo Costa, Tino Emanuele Poloni, Tino Emanuele Poloni

“…Despite their prevalence, their underlying mechanisms and neuropathological correlates, remain poorly understood. …”
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Gut microbiota and inflammasome-mediated pyroptosis: a bibliometric analysis from 2014 to 2023 by Hang Zhang, Hang Zhang, Hang Zhang, Tian Zhao, Tian Zhao, Tian Zhao, Juan Gu, Juan Gu, Fushan Tang, Fushan Tang, Fushan Tang, Lei Zhu, Lei Zhu, Lei Zhu

“…However, an in-depth analysis, through studies is crucial to uncover and elucidate the complex mechanisms linking these elements.…”
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Factors Associated with Poor Ovarian Reserve in Young Infertile Women: A Hospital-based Cohort Study by Sanghamitra Hazarika, Paapa Dasari, Sairem Mangolnganbi Chanu, Sharbari Basu

“…This could be a confounder for other underlying mechanisms driving early exhaustion of ovarian reserve in certain young women. …”
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hCTLA4-Gene-Modified Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMMSCs) Maintain POSTN Secretion to Enhance the Migration Capability of Allogeneic hBMMSCs through the Integ... by Lei Song, Fei Zhang, Rui Zhou, Jun Xiao, Lei He, Fei Dai

“…However, the underlying mechanism is not clear. In the present study, we investigated whether CTLA4-modified hBMMSCs are involved in the migration of allogeneic hBMMSCs (allo-hBMMSCs) by maintaining POSTN secretion. hBMMSCs were isolated from different groups, named hBMMSCs and allo-hBMMSCs. hBMMSCs that were infected with the negative control (NC), empty adenovirus- or recombinant adenovirus-expressing CTLA4, POSTN, or CTLA4 plus the shRNA of POSTN were named NC hBMMSCs, CTLA4-modified hBMMSCs, POSTN-modified hBMMSCs, or CTLA4+shPOSTN-modified hBMMSCs, respectively. …”
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miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding by Juan Wen, Baiyi Tang, Lan Guo, Wei Chen, Xiaohong Tang

“…However, the molecular mechanisms behind these pathological processes in hypertension are not fully elucidated. …”
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Adaptive Hosting Capacity Forecasting in Distribution Networks with Distributed Energy Resources by Md Tariqul Islam, M. Jahangir Hossain, Md. Ahasan Habib, Muhammad Ahsan Zamee

“…Additionally, a feedback mechanism within the model provides inputs from previous cell states into the forget gate, allowing for refined control over input selection and enhancing forecasting precision. …”
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Oral Cancer Stem Cell-Derived Small Extracellular Vesicles Promote M2 Macrophage Polarization and Suppress CD4+ T-Cell Activity by Transferring UCA1 and Targeting LAMC2 by Lan Wu, Sai Ye, Yilin Yao, Chenping Zhang, Wei Liu

“…Our findings provide a new understanding of OSCC-CSC molecular mechanisms and suggest a potential therapeutic strategy for OSCC through targeting CSC-sEVs and M2-TAMs.…”
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Electroacupuncture Pretreatment Elicits Tolerance to Cerebral Ischemia/Reperfusion through Inhibition of the GluN2B/m-Calpain/p38 MAPK Proapoptotic Pathway by Bao-yu Zhang, Guan-ran Wang, Wen-hua Ning, Jian Liu, Sha Yang, Yan Shen, Yang Wang, Meng-xiong Zhao, Li Li

“…To investigate whether EA pretreatment based on TCM theory could elicit cerebral tolerance against ischemia/reperfusion (I/R) injury, and explore its potential excitotoxicity inhibition mechanism from regulating proapoptotic pathway of the NMDA subtype of glutamate receptor (GluN2B). …”
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Exploration of key genes and pathways in response to submergence stress in red clover (Trifolium pratense L.) by WGCNA by Panpan Shang, Lei Bi, Wenwen Li, Xiaoli Zhou, Yanlong Feng, Jiahai Wu, Bing Zeng

“…Conclusion In this study, using WGCNA, the molecular response mechanisms of red clover to submergence stress was proposed, and the core genes and metabolic pathways in response to submergence stress were obtained, providing a valuable data resource at the physiological and molecular levels for subsequent studies of submergence stress tolerance in plants.…”
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International Experience in Assessing Economic Security: Basic Approaches and Opportunities for Ukraine by D. O. Koshikov

“…It has been concluded that the national method of calculating the level of economic security of Ukraine needs to be improved by introducing into its system the indicators of state agencies’ work in the relevant area, defining criteria and indicators for combating economic crime and corruption, improving the mechanism of collecting primary data by adding sociological research, expert assessments and research of foreign financial institutions.…”
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Stress contingent changes in Hog1 pathway architecture and regulation in Candida albicans. by Alison M Day, Min Cao, Alessandra da Silva Dantas, Olga Ianieva, Carmen Herrero-de-Dios, Alistair J P Brown, Janet Quinn

“…Furthermore, we find that inhibition of protein tyrosine phosphatases is linked to the hydrogen peroxide induced oxidation of these negative regulators in a mechanism that is partly dependent on thioredoxin. …”
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Light-regulated microRNAs shape dynamic gene expression in the zebrafish circadian clock. by Zuo Wang, Shuang Wang, Yi Bi, Alessandra Boiti, Shengxiang Zhang, Daniela Vallone, Xianyong Lan, Nicholas S Foulkes, Haiyu Zhao

“…However, considerable evidence points to post-transcriptional regulatory mechanisms, notably microRNAs (miRNAs), playing an essential role in shaping dynamic changes in mRNA levels. …”
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CircBAZ1B stimulates myocardial ischemia/reperfusion injury (MI/RI) by modulating miR-1252-5p/ATF3-mediated ferroptosis by Ruili Wei, Tianxiao Yang, Weihong Li, Xiqian Wang

“…Here, we focused on the biological function and regulatory mechanism of circBAZ1B, a circRNA derived from the bromodomain adjacent to the zinc finger domain 1B (BAZ1B) gene, in MI/RI progression. …”
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KMO-driven metabolic reconfiguration and its impact on immune cell infiltration in nasopharyngeal carcinoma: a new avenue for immunotherapy by Nijun Chen, Yuan Zong, Chen Yang, Lei Li, Yang Yi, Jiawen Zhao, Xiaoyu Zhao, Xianfei Xie, Xingmei Sun, Ning Li, Liting Jiang

“…Furthermore, KMO expression was negatively correlated with DNA repair mechanisms and hypoxia. In addition, KMO levels were inversely associated with the upregulation of both oxidative phosphorylation (OXPHOS) and glycolysis pathways within the NPC tumor microenvironment (TME). …”
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