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37361
Transition metal-based MOFs for Fenton-like photocatalytic degradation of organic pollutants: Performance, stability, and biocompatibility
Published 2025-01-01“…FeBDC achieved a reaction rate constant of 0.2719 min−1 with 50 mmol/L H₂O₂, outperforming other materials due to its superior visible-light absorption and catalytic activity, which justified its selection for more detailed mechanistic studies. The proposed mechanism involves ligand-to-metal charge transfer (LMCT) and Fe-driven generation of reactive oxygen species (ROS) such as hydroxyl radicals. …”
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37362
Anti-inflammatory effect of sea buckthorn in an HCl-induced cystitis rat model
Published 2025-01-01“…"Purpose: Although the mechanism underlying interstitial cystitis/bladder pain syndrome (IC/BPS) remains unclear, oxidative stress is suggested to be implicated in IC/BPS development. …”
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37363
Cyclophilin–CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8
Published 2025-02-01“…Taken together, our data reveal a novel mechanism how human monocytes sense SARS-CoV-2 and suggest that targeting the cyclophilin-CD147 axis might be beneficial to alleviate overt myeloid-driven inflammation triggered by SARS-CoV-2 infection.…”
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37364
The relationship between negative psychological state and quality of life among cardiovascular disease patients in China: the masking effect of abnormal dietary behavior
Published 2025-02-01“…The purpose of this study was to construct a moderated mediation model to explore the roles of abnormal dietary behavior and family health in the mechanism through which depression/anxiety influences Quality of life (QoL) in patients with cardiovascular disease.MethodsA field survey was conducted in China and ultimately included 730 patients with cardiovascular disease aged 20–60 years. …”
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37365
Exploring the relationship between trunk flexibility and arterial stiffness measured by pulse wave velocity: A systematic review and meta-analysis.
Published 2024-01-01“…<h4>Conclusion</h4>Poor trunk flexibility is linked to elevated arterial stiffness across diverse demographic groups, highlighting its potential as a surrogate marker for cardiovascular health. Physiological mechanisms involving connective tissue integrity and neural regulation may underpin this relationship. …”
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37366
Research on Territorial Spatial Use Regulation, Land Element Allocation, and Regional Fiscal Transfer Payments: An Empirical Study of the Yangtze River Economic Belt
Published 2025-01-01“…Currently, the state should establish a comprehensive regional fiscal transfer compensation mechanism that takes into account the fiscal payment capacities of “windfall profit regions” and the incentive effects on “windfall loss regions” when determining fiscal transfer amounts. …”
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37367
Repression of PFKFB3 sensitizes ovarian cancer to PARP inhibitors by impairing homologous recombination repair
Published 2025-01-01“…RNA sequencing and proximity labeling were employed to identify the molecular mechanisms underlying PFKFB3-mediated resistance. The in vivo efficacy of PARPi and PFK158 combination therapy was evaluated in OC xenograft models. …”
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37368
Analysis of the relevant factors for corneal graft rejection in the southern Liaoning region from 2019 to 2023
Published 2025-01-01“…Viral infections (p < 0.001, OR = 16.871) were the major risk factor for preoperative corneal neovascularization (CNV) compared to other etiologies, such as fungal infections (p < 0.001, OR = 0.018), mechanical ocular trauma (p < 0.001, OR = 0.034), immune keratitis (p = 0.023, OR = 0.152), and endothelial dysfunction (p < 0.001, OR = 0.054).ConclusionInfectious keratitis was identified as the major cause of corneal blindness in the southern Liaoning region over the past 5 years. …”
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37369
High-Performance Hydrogen Sensing at Room Temperature via Nb-Doped Titanium Oxide Thin Films Fabricated by Micro-Arc Oxidation
Published 2025-01-01“…The enhanced hydrogen sensing mechanism of NTO thin films primarily stems from the influence of Nb<sub>2</sub>O<sub>5</sub>; nanoparticles doping in the anatase-phase TiO<sub>2</sub> structure on the semiconductor surface depletion layer, as well as the improved charge transfer and additional adsorption sites provided by the Nb/Ti composite metal oxides, such as TiNb<sub>2</sub>O<sub>7</sub> and Ti<sub>0.95</sub>Nb<sub>0.95</sub>O<sub>4</sub>. …”
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37370
Genomic Characterization of Carbapenemase-Producing Enterobacteriaceae from Clinical and Epidemiological Human Samples
Published 2025-01-01“…Genomic characterization is essential to understanding resistance mechanisms, aiding therapy, limiting outbreaks, and improving precision medicine.…”
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37371
The role of long non-coding RNA LINC00839 in oral squamous cell carcinoma based on bioinformatics and experimental research
Published 2024-12-01“…This discovery reveals a novel regulatory mechanism underlying OSCC tumorigenesis and may provide effective diagnosis and potential therapeutic targets to cure this devastating cancer.…”
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37372
Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression
Published 2025-01-01“…Our results provide new insight into the mechanism of OSCC progression and suggest that the FASN of OSCC-MSCs may be potential targets of OSCC in the future.…”
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37373
Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study
Published 2025-02-01“…Recent evidence suggests a bidirectional link between endometriosis and brain functional networks, though the causal mechanisms remain unclear. This study aims to explore these relationships using Mendelian Randomization (MR) analysis.Methods: Data from 191 resting-state functional MRI (rsfMRI) phenotypes and endometriosis genetic datasets were analyzed using both forward and reverse MR approaches. …”
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37374
The impacts of reduced ice sheets, vegetation, and elevated CO2 on future Arctic climates
Published 2024-12-01“…This study emphasizes the value of integrating paleoclimate insights into future climate projections and underscores the need for a more detailed examination of feedback mechanisms to enhance the robustness of climate models.…”
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37375
Torque visuomotor feedback training versus standard eccentric exercise for the management of patellar tendinopathy: protocol for a randomised controlled trial
Published 2025-02-01“…To gain insights on mechanisms of action for potential improvements, motor unit discharge characteristics of the quadriceps femoris muscles will be assessed with high-density surface electromyography. …”
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37376
On the substrate turnover rate of NBCe1 and AE1 SLC4 transporters: structure-function considerations
Published 2025-01-01“…Comparison of this IF model with our previously determined cryoelectron microscopy (cryoEM) outward-facing (OF) conformation structure, demonstrates that NBCe1-A has an elevator-type transport mechanism with a small vertical ∼5 Å shift of the ion coordination site as we have previously shown for AE1. …”
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37377
Exposure to triphenyl phosphate during pregnancy: The role of gut-bile acids-liver axis on lipid metabolism in male offspring
Published 2025-01-01“…Overall, our findings indicate that gestational TPhP exposure induces hyperlipidemia in male offspring, and while the gut-BAs-liver axis plays a role, other mechanisms warrant further investigation.…”
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37378
Wear Behavior Analysis and Gated Recurrent Unit Neural Network Prediction of Coefficient of Friction in Al10Cu-B<sub>4</sub>C Composites
Published 2024-12-01“…These characteristics make them perfectly suited for applications demanding exceptional performance in extreme mechanical and tribological environments. This study investigates the wear behavior, microstructural characteristics, and predictive modeling of Al10Cu-B<sub>4</sub>C composites fabricated via powder metallurgy with varying B<sub>4</sub>C contents (0, 2.5, 5, and 7.5 wt.%). …”
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37379
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway
Published 2022-01-01“…Gut microbiota imbalance in PE patients is accompanied by elevated serum lipopolysaccharide (LPS) levels, but whether it affects the occurrence and development of PE, the underlying mechanism is not clear. This paper intends to investigate the relationship between lncRNA BC030099, inflammation, and gut microbiota in PE. …”
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37380
Profiles and natural drivers of antibiotic resistome in multiple environmental media in penguin-colonized area in Antarctica
Published 2025-01-01“…Profiles and driving mechanisms of antibiotic resistome in the polar region are important for exploring the natural evolution of antibiotic resistance genes (ARGs). …”
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