Baicalin Mitigates Cardiac Hypertrophy and Fibrosis by Inhibiting the p85a Subunit of PI3K by Lu He, Min Zhu, Rui Yin, Liangli Dai, Juan Chen, Jie Zhou

“…However, the underlying mechanism(s) of the cardioprotective effect of baicalin are still not fully understood. …”
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Acute Kidney Injury Complicating Critical Forms of COVID-19: risk Factors and Prognostic Impact [version 3; peer review: 2 approved] by Ghadhoune Hatem, Yosra Yahia, Olfa Hammami, Hend Allouche, Insaf Trabelsi, Jihene Guissouma, Hana Ben Ali

“…In fact, age > 53 years (p: 0.018), septic shock complicating hospital acquired infection (p: 0.003) and mechanical ventilation (p<0.001) were the three prognostic factors in multivariate analysis. …”
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Rotting Sounds . Artistic Research Practice in Experimental Sound Art by Thomas Grill, Till Bovermann, Almut Schilling

“…The multi-year artistic research project Rotting Sounds has investigated the causes, mechanisms, and effects of such deterioration, specifically in the context of digital audio. …”
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A New X-Ray and Radio Burst Activity from the Magnetar SGR 1935+2154 by Noor S. Rehan, Alaa I. Ibrahim

“…We discuss the results in the context of the new emission models that propose physical mechanisms for the X-ray and radio burst emission from magnetars.…”
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Strengthening mycology research through coordinated access to microbial culture collection strains by D. Smith, A. Kermode, G. Cafà, A. G. Buddie, T. S. Caine, M. J. Ryan

“…All of the above may be achieved by individual institutions but, by working together, collections can form a critical mass to focus on key global issues and can achieve much more. Mechanisms are suggested for coordinating collections in order to deliver a more comprehensive support system in the advancement of science and innovation.…”
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DNA methylation of leptin before and after weight loss intervention program among sample of Egyptian obese females: Epigenetic approach in obesity by Nayera E. Hassan, Sahar A. El-Masry, Waheba A. Zarouk, Nayra S. Mehanna, Rehab M. Mosaad, Maha M Kobesiy, Mohamed S. Kishta, Mohamed Selim, Mahmoud A.S. Afify, Khadija Alian, Aya Khalil, Heba T. Aboud

“…DNA methylation constitutes the most relevant epigenetic mechanism that regulates gene expression in human cells. …”
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ASSESMENT OF THE ROLE OF STAKEHOLDERS IN THE MANAGEMENT OF BORDER INSECURITY USING AHP. A CASE STUDY OF GURIN-FOFURE, ADAMAWA STATE. by JOLLY P. M, MUAZU H. G.

“… Despite the mechanisms put in place to address border insecurity, the challenge still exists on the global scale, which is more pronounced at both regional and local levels. …”
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New era, new GOALs: cardiovascular screening and lipid management in cystic fibrosis by Katherine A. Despotes, Agathe S. Ceppe, Jennifer L. Goralski, Scott H. Donaldson

“…While cholesterol levels were historically low in pwCF, higher levels after initiating highly effective modulator therapy (HEMT) have been reported. Mechanisms are unclear and there is little guidance on screening. …”
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Capacity and market potential for local production and distribution of electric two-wheelers in Southeast Asia, focused on Thailand, Indonesia and Vietnam by Hyung Ju Kim, Shritu Shrestha, Kanya Pranawengkapti

“…This paper advocates for collaborative initiatives across digital platforms, financial mechanisms, and supportive government policies to accelerate the adoption of electric 2Ws (E2Ws) by promoting local production, fostering innovative business models, and establishing conducive regulatory frameworks. …”
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Unraveling pathogenesis and potential biomarkers for autism spectrum disorder associated with HIF1A pathway based on machine learning and experiment validation by Jinru Cui, Heli Li, Cong Hu, Feiyan Zhang, Yunjie Li, Ying Weng, Liping Yang, Yingying Li, Minglan Yao, Hao Li, Xiaoping Luo, Yan Hao

“…Hypoxic condition of the brain is considered an important pathological mechanism of ASD. HIF1A is a key participant in brain hypoxia, but its contribution to the pathophysiological landscape of ASD remains unclear. …”
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Numerical Analysis on the Load Sharing Performance of Long-Short CFG Pile Composite Foundation Subjected to Rotation of Adjacent Retaining Wall by Bantayehu Uba Uge, Yuancheng Guo, Yunlong Liu

“…The stress and displacement boundary conditions of excavation retaining structures affect the deformation mechanism and movement of the retained soil mass. The soil movement disturbs the load sharing performance and structural integrity of cement-fly ash-gravel (CFG) pile composite foundations existing in the vicinity, which merits considerable research work. …”
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miR-129-5p Promotes Osteogenic Differentiation of BMSCs and Bone Regeneration via Repressing Dkk3 by Changming Zhao, Yulin Gu, Yan Wang, Qiaozhen Qin, Ting Wang, Meng Huang, Heyang Zhang, Yannv Qu, Jingwen Zhang, Zhangzhen Du, Xiao-Xia Jiang, Lulu Xu

“…However, the associated mechanisms remain elusive. This paper is aimed at exploring the role of miR-129-5p in regulating bone marrow mesenchymal stem cell (BMSC) differentiation and bone regeneration in vivo and in vitro. …”
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Lactobacillus salivarius metabolite succinate enhances chicken intestinal stem cell activities via the SUCNR1-mitochondria axis by Danni Luo, Minyao Zou, Xi Rao, Mingping Wei, Lingzhi Zhang, Yuping Hua, Lingzi Yu, Jiajia Cao, Jinyi Ye, Sichao Qi, Huanan Wang, Yuling Mi, Caiqiao Zhang, Jian Li

“…However, the underlying mechanisms remain unclear. In this study, a total of 189 Hy-Line Brown chickens (Gallus) were randomly assigned to one of seven experimental groups (n = 27 per group). …”
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Effect of colchicine on physiological and biochemical properties of <i>Rhodococcus qingshengii</i> by Yu. A. Markova, L. A. Belovezhets, V. N. Nurminsky, I. S. Kapustina, N. V. Ozolina, V. V. Gurina, A. L. Rakevich, A. V. Sidorov

“…Colchicine was previously found to reduce biof ilm formation by P. carotovorum VKM B-1247 and R. qingshengii VKM Ac-2784D. To understand the mechanism of action of this alkaloid on the bacterial cell, we have studied the change in the fatty acid composition and microviscosity of the R. qingshengii VKM Ac-2784D membrane. …”
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Spleen tyrosine kinase inhibitors disrupt human neutrophil swarming and antifungal functions by Alex Hopke, Adam L. Viens, Natalie J. Alexander, Seok Joon Mun, Michael K. Mansour, Daniel Irimia

“…However, the molecular mechanisms controlling this process are just emerging. …”
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Laminated Veneers with Stratified Feldspathic Ceramics by Henrique Tuzzolo Neto, Wagner Ferreira do Nascimento, Larissa Erly, Rodrigo Alves Ribeiro, Jorge de Sá Barbosa, Jessica Mina Zambrana, Lariça Barbosa Raimundo, Cristiane da Silva Mendes, Ivan Pereira da Silva, Alfredo Mikail Melo Mesquita, Daniela Miranda Richarte de Andrade Salgado, Claudio Costa

“…Through careful treatment planning, it is possible to conservatively use ceramic veneers in the treatments, applying techniques with minimal wear of the teeth and obtaining excellent aesthetic results with mechanical stability and biocompatibility with the periodontal tissues and clinical longevity. …”
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Study on the Key Influential Factors on Water Huff-n-Puff in Ultralow-Permeability Reservoir by Xiaoyan Wang, Kun Xie, Jie Zhang, Yong Zhang, Yang Zhang, Wei Wang, Xi Yan, Fengxiang Zhao

“…The results show that imbibition and energy supplement are main mechanisms of water huff-n-puff; imbibition oil recovery is influenced by rock wettability, permeability, boundary condition, fracture length, water injection speed, and imbibition solution type; the stronger the water-wet reservoir rock is, the bigger the core permeability is, the longer the fracture length is, the larger the contacting area between imbibition solution and rock is, the stronger the ability of imbibition solution to change wettability, and to reduce the interfacial tension force between oil and water is, the better effect of water huff-n-puff is. …”
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Investigation into the Pore Structure and Multifractal Characteristics of Shale Reservoirs through N2 Adsorption: An Application in the Triassic Yanchang Formation, Ordos Basin, Ch... by Zhikai Liang, Zhenxue Jiang, Zhuo Li, Fenglin Gao, Xiaoqing Liu

“…To understand the pore structure and heterogeneity of pore size distribution (PSD) is essential for revealing fluid mechanics and evaluating the utilization of unconventional resources. …”
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A Strategy to Revalue a Wood Waste for Simultaneous Cadmium Removal and Wastewater Disinfection by Aleksandra Ivanovska, Sonja Veljović, Biljana Dojčinović, Nenad Tadić, Katarina Mihajlovski, Maja Natić, Mirjana Kostić

“…According to ATR-FTIR spectra, aldehyde, carboxyl, hydroxyl, and phenyl groups present on the wood waste surface are involved in Cd2+ adsorption which proceeds via the interplay of the complexation, cation-π interactions, and ion-exchange mechanisms. Mulberry and myrobalan plum showed about 89% and 80% of the total uptake capacity of cadmium within 60 min, while the equilibrium was attained after 240 min of contact time. …”
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Endoplasmic reticulum stress in the salivary glands of patients with primary and associated Sjögren’s disease, and non-Sjögren’s sicca syndrome: a comparative analysis and the infl... by Graziela Vieira Cavalcanti, Fabiola Reis de Oliveira, Rafael Ferraz Bannitz, Natalia Aparecida de Paula, Ana Carolina Fragoso Motta, Eduardo Melani Rocha, John Chiorini, Hilton Marcos Alves Ricz, Denny Marcos Garcia, Maria Cristina Foss-Freitas, Luiz Carlos Conti de Freitas

“…Abstract Background Endoplasmic reticulum stress (ERS) and the unfolded protein response (UPR) are adaptive mechanisms for conditions of high protein demand, marked by an accumulation of misfolded proteins in the endoplasmic reticulum (ER). …”
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