Adjustment of prudential norms, determining vector of the banking sector development by N. V. Gryzunova

“…The urgency proportional distribution of regulatory indicators of banking supervision by tier banking system, which are formed from the pacing of functional and regional specificity, – has been substantiated. The mechanism of price stability based on the clustering of financial institutions has been offered. …”
Get full text

Serum metabolome associated with novel and legacy per- and polyfluoroalkyl substances exposure and thyroid cancer risk: A multi-module integrated analysis based on machine learning by Fei Wang, Yuanxin Lin, Lian Qin, Xiangtai Zeng, Hancheng Jiang, Yanlan Liang, Shifeng Wen, Xiangzhi Li, Shiping Huang, Chunxiang Li, Xiaoyu Luo, Xiaobo Yang

“…Additionally, little is known about the potential mechanisms underlying the association. Objectives: Explore the effects of PFAS exposure on the serum metabolome and its correlation with TC. …”
Get full text

On the pursuit of reproducibility: the importance of large sample sizes in psychoimmunology by Manivel Rengasamy, Daniel Moriarity, Rebecca Price

“…., number/choice of covariates) will maximize reproducibility of psychoimmunology studies related to depression to enhance development of treatments for depression or to help understand pathophysiological mechanisms of depression.…”
Get full text

Stigma and social support and their impact on quality of life and self-esteem among women with endometriosis in Latin-America and the Caribbean. by Yatzmeli Matías-González, Astrid Sánchez-Galarza, Ernesto Rosario-Hernández, Idhaliz Flores-Caldera, Eliut Rivera-Segarra

“…Findings suggest stigma could be one of the mechanisms through which the relationship between incapacitating pain and self-esteem among Latin American and Caribbean women with endometriosis could be partially explained. …”
Get full text

IGF2BP2 Regulates the Progression of Alzheimer's Disease Through m6A‐Mediated NLRP3 Inflammasome by Wu Jingrui, Yang Haihui, Yan Jinjin, Fang Le

“…ABSTRACT Background Recent studies show that N6‐methyladenosine (m6A) plays an important role in the pathogenesis of the Alzheimer's disease (AD), while the mechanisms involved were studied insufficiently. Aims The present study aimed to explore the effect of human insulin‐like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2), one of the m6A‐binding proteins on the progression of AD. …”
Get full text

Determinants of burnout syndrome among undergraduate nursing students in Poland: a cross-sectional study by Katarzyna Szwamel, Wiesława Kowalska, Ewa Mazur, Anna Janus, Iwona Bonikowska, Justyna Jasik-Pyzdrowska

“…Depending on the results of the tests, implementation of interventions aiming at reducing the negative outcomes of burnout syndrome and promoting well-being and adaptive management mechanisms should be considered.…”
Get full text

Peculiarities of Legal Regulation of Non-Discrimination on Gender Basis while Being Employed by A. V. Kuchko

“…In this regard, the author has emphasized the importance of the existence of a wide range of effective legal principles in the national labor legislation for non-discrimination while employment, in particular on the grounds of sex, as well as an effective mechanism for their realization. It has been clarified that the legal regulation of non-discrimination on the grounds of sex while employment is the legal regulation of labor and closely related relations through legal means in order to achieve gender parity, prevention of any manifestations of gender discrimination in the realization of the right to labor by each person and citizen. …”
Get full text

Children’s Eating Behavior Questionnaire Correlated with Body Compositions of Thai Children and Adolescents with Obesity: A Pilot Study by Ekkarit Panichsillaphakit, Yuda Chongpison, Puthita Saengpanit, Tanisa Kwanbunbumpen, Jaraspong Uaariyapanichkul, Sirinuch Chomtho, Chitsanu Pancharoen, Chonnikant Visuthranukul

“…Additional study with a larger sample size needed to explore underlying mechanisms and findings can be used to develop future behavior modification program.…”
Get full text

Assessing safety culture and second victim experience following adverse events among Romanian nurses: a cross-sectional study by Mirabela Ioana Istrate, Alina Ioana Forray, Marius-Ionuț Ungureanu, José Joaquín Mira, Sorana Alexandra Constantinescu, Răzvan Mircea Cherecheș

“…With a limited body of research on patient safety, adverse events, and second victims (SVs) in Romania, this study addresses a crucial gap, highlighting the need for enhanced safety culture and support mechanisms for SVs. Methods A cross-sectional study in Romania targeted healthcare professionals, focusing on nurses. …”
Get full text

Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and a... by Zang Binbin, Wang Lihui

“…The current work was conducted to elucidate the pharmacological effect of pyrazole-conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in rats in sepsis and their mechanism of action. Various pyrazole-conjugated imidazo[1,2-a]-pyrazine derivatives have been synthesized in a straightforward synthetic route. …”
Get full text

Bioinformatic identification of important roles of COL1A1 and TNFRSF12A in cartilage injury and osteoporosis by Muzi Liu, Shiguo Gong, Xin Sheng, Zihong Zhang, Xichun Wang

“…Objective The aim of this study was to identify the key regulatory mechanisms of cartilage injury and osteoporosis through bioinformatics methods, and to provide a new theoretical basis and molecular targets for the diagnosis and treatment of the disease.Methods Microarray data for cartilage injury (GSE129147) and osteoporosis (GSE230665) were first downloaded from the GEO database. …”
Get full text

Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo by Yanfei Li, Dafa Shi, Haoran Zhang, Xiang Yao, Ke Ren

“…Background. The definitive mechanisms of CI-AKI include contrast medium (CM) nephrotoxicity and CM disturbances in renal blood flow, but how the immune system responds to CM has rarely been mentioned in previous studies, and different cell death pathways have not been clearly distinguished. …”
Get full text

The Effect of Strength Training on the Quality of Life and Cognitive Functions of Elderly People by Ernesta Klimavičiūtė, Sandra Naujalė, Lina Mickevičienė, Erika Krasinskė, Margarita Drozdova – Statkevičienė, Vida Janina Česnaitienė

“…Possible biological mechanisms that may underlie the effectiveness of physical exercise include increased blood flow in the brain, changes in neurotransmitter release, and the process of neurogenesis (Sumińska, 2021). …”
Get full text

Potential Medicinal Fungi from Freshwater Environments as Resources of Bioactive Compounds by Ilenia Cicero, Giulia Mirabile, Giuseppe Venturella

“…Several studies are available in the literature about in vitro and in vivo mechanisms of actions of such bioactive compounds. Most of these surveys are focused on macrofungi belonging to the genera <i>Pleurotus</i>, <i>Ganoderma</i>, or specific taxa such as <i>Agaricus bisporus</i>, <i>Agaricus blazei</i>, <i>Boletus eduliInonotus obliquus</i>, <i>Hericium erinaceus</i>, <i>Lentinula edodes</i>, and <i>Grifola frondose</i>. …”
Get full text

Evaluation of Competency-Based Medical Education (CBME) curriculum implementation for Phase II Medical undergraduates: A qualitative study by KRISHNAMURTHY SOUNDARIYA, ANANDABASKAR NISHANTHI, RAJALAKSHMI MAHENDRAN, MOUROUGUESSINE VIMAL

“…The key outcome of the study was establishing various subcommittees within the Curriculum Committee and Medical Education Unit to facilitate the implementation of various CBME components, supported by regular feedback mechanisms. Also, the action plan was shared with the Medical Education Unit to organize appropriate faculty development programs.…”
Get full text

Enhancing precision in cancer treatment: the role of gene therapy and immune modulation in oncology by Emile Youssef, Brandon Fletcher, Dannelle Palmer

“…CRISPR-Cas9, a revolutionary tool in precision medicine, enables precise editing of cancer-driving mutations, enhancing immune responses and disrupting tumor growth mechanisms. Additionally, emerging approaches target ferroptosis—a regulated, iron-dependent form of cell death—offering new possibilities for selectively inducing tumor cell death in resistant cancers. …”
Get full text

Patient perspectives on stress after ICU and a short primary care based psychological intervention – results from a qualitative sub‑study of the PICTURE trial by Antina Beutel, Linda Sanftenberg, Chris M. Friemel, Robert Philipp Kosilek, Maggie Schauer, Thomas Elbert, Ulf-Dietrich Reips, Tomke Schubert, Sabine Gehrke-Beck, Konrad Schmidt, Jochen Gensichen, for the PICTURE study group

“…All of them had experienced an ICU stay with mechanical ventilation and severe organ failure in the previous two years. …”
Get full text

Stan biologiczny populacji ludzkich a przemiany środowiska społeczno-ekonomicznego by Anna Siniarska, Napoleon Wolański

“…However, variability can also be generated during individual ontogeny at least by protective mechanisms of instinctive behaviors of animals and conscious cultural human actions. …”
Get full text

Patient engagement in radiation oncology: a large retrospective study of survey response dynamics by Bailey A. Loving, Hong Ye, Elizabeth Rutka, John M. Robertson

“…Strategies to enhance patient engagement must consider these diverse influences to ensure comprehensive and inclusive feedback mechanisms in healthcare settings. Tailored interventions to mitigate barriers specific to underrepresented groups are crucial for capturing a broad spectrum of patient experiences and improving the overall quality of patient care.…”
Get full text

Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes by Setareh Mamishi, Reihaneh Hosseinpour Sadeghi, Sadaf Sajedi Moghaddam, Babak Pourakbari, Shiva Poormohammadi, Maryam Sotoudeh Anvari, Shima Mahmoudi

“…Purpose This study aimed to investigate the prevalence of carbapenem resistance in gram-negative bacteria isolated from patients at the Children's Medical Center Hospital, Tehran, Iran, to understand the molecular mechanisms underlying this resistance. Methods During the period spanning from June 2019 to June 2020, 777 gram-negative bacterial strains were isolated. …”
Get full text