Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction by Xiaolong Qu, Pan Yang, Li Jiao, Yuehui Yin

“…AMPK pathway inhibitor compound C was used for further mechanism validation. …”
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Molecular assessment of NMDAR subunits and neuronal apoptosis in the trigeminal ganglion in a model of male migraine-induced rats following Moringa oleifera alcoholic extract admin... by Ahmad Vafaeian, Ali Vafaei, Mohammad Reza Parvizi, Mohsen Chamanara, Mojgan Mehriardestani, Yasaman Hosseini

“…This study aims to assess the efficacy and precise mechanisms of M. oleifera for the treatment of migraine, for which evidence is limited. …”
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A systematic scoping review on the consequences of stress-related hyperglycaemia. by Elena Olariu, Nicholas Pooley, Aurélie Danel, Montserrat Miret, Jean-Charles Preiser

“…The most frequently reported outcomes were mortality (38 studies), ICU and hospital length of stay (23 and 18 studies, respectively), and duration of mechanical ventilation (13 studies). The majority of these studies (40 studies) compared the reported outcomes in patients who experienced SHG with those who did not. …”
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Niche and interspecific association of dominant arbor species in Quercus communities in the Qinling Mountains, China by Ruizhi Huang, Qi Wang, Jingyi Sun, Yipei Zhao, Shaowei Yang, Wenfa Xiao, Jianfeng Liu

“…Study of niche characteristics, species interactions and community connectivity along elevation gradients contributes to our understandings on species' spatial interactions and vicarious distribution pattern, and helps reveal congeneric species coexistence and formation mechanisms of species distribution boundaries. In this study, we conducted a field survey on five types of Quercus communities across six elevation belts ranging from 900 to 2300 m (a.s.l) on the north and south slopes of Qinling Mountains, where the north subtropical and warm temperate zones divide. …”
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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

“…Further research is needed to understand the underlying mechanisms and to explore the potential of iron-targeted therapies.…”
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ESBL- and pAmpC-producing Enterobacterales from Swedish dogs and cats 2017–2021: a retrospective study by Anna Bonnevie, Mattias Myrenås, Oskar Nilsson

“…Of special concern are resistance mechanisms that are transmissible between bacteria, such as extended-spectrum beta-lactamases (ESBL) and plasmid-mediated AmpC (pAmpC). …”
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Association between serum endocan levels and organ failure in hospitalized patients with cirrhosis. by Salisa Wejnaruemarn, Sirinporn Suksawatamnuay, Jakapat Vanichanan, Piyawat Komolmit, Sombat Treeprasertsuk, Kessarin Thanapirom

“…Liver failure, hospital-acquired infection, mechanical ventilator use, and interleukin-6 ≥37 pg/mL were independent predictors of 28-day mortality.…”
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“National Champions” and Technological “Little Giants”: Chinese Industrial Policy Between Modernization and Tradition by I. V. Danilin

“…These include an analysis of support mechanisms for small and medium-sized enterprises (SMEs)—particularly the so-called "small giants"—as a key example of the implementation of the "national champions" policy. …”
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Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…Conclusions: This study confirms the therapeutic efficacy of H2S in facilitating the recovery of injured endometrium and revealed its potential therapeutic mechanism, offering a promising therapeutic avenue for patients with severe endometrial injury.…”
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Modeling Ebola Virus Disease transmissions with reservoir in a complex virus life ecology by Tsanou Berge, Samuel Bowong, Jean Lubuma, Martin Luther Mann Manyombe

“…Secondly it takes into account the well-known, the probable/suspected and the hypothetical transmission mechanisms (including direct and indirect routes of contamination) between and within the three different types of populations consisting of humans, animals and fruit bats. …”
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Effects of acupuncture at the Taichong (LIV3) and Hegu (LI4) points on functional connectivity with the retrosplenial cortex in patients with Alzheimer’s disease by Junkai Wang, Xinyue Bai, Xiaojun Chen, Shui Liu, Mengmeng Sun, Kuncheng Li, Yunsong Zheng, Zhiqun Wang

“…BackgroundAcupuncture has been demonstrated to have a promising effect on Alzheimer’s disease (AD), but the underlying neural mechanisms remain unclear. The retrosplenial cortex (RSC) is one of the earliest brain regions affected in AD, and changes in its functional connectivity (FC) are reported to underlie disease-associated memory impairment. …”
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B Lymphocyte—A Prognostic Indicator in Post‐Acute Pancreatitis Diabetes Mellitus by Xiaoyan Lin, Xiaoling Li, Junsheng Wang, Huiheng Liu

“…Furthermore we indicated that age, fatty liver, serous effusion, recurrent AP, and B% were independent risk factors for PPDM‐A. The mechanism of granulocyte and monocyte surface markers and B lymphocytes on PPDM‐A is worthy of study. …”
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Exploring the influence of “keeping consumers in suspense” in live streaming on consumer impulse buying behavior: A test of the mediating effects of consumer inner states by Xiangxi Kong, Ren Wang, Yuyang Zhang

“…Conclusion: KCIS strategies play a pivotal role in shaping consumer behavior in live-streaming e-commerce by influencing impulse buying through mechanisms such as value and expectation perception. …”
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Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways by Xiao Chen, Luping Lin, Qiaoling Wu, Sang Li, Huihui Wang, Yang Sun

“…Tumor necrosis factor-α (TNF-α) was found to be closely associated with lymphatic cancer metastasis. However, the mechanism through which TNF-α regulates lymphatic metastasis in cervical cancer remains unclear. …”
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The international trial of nasal oxygen therapy after cardiac surgery (NOTACS) in patients at high risk of postoperative pulmonary complications: Economic evaluation protocol and a... by Siddesh Shetty, Melissa Duckworth, Richard Norman, Jacquita Affandi, Sarah Dawson, Julia Fox-Rushby, NOTACS investigators, NOTACS Trial Steering Committee, NOTACS DMEC Committee

“…Missing data will be assessed, with values replaced depending on assumed mechanism of missingness, and impact of replacement on cost-effectiveness assessed. …”
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Do meteorological variables impact air quality differently across urbanization gradients? A case study of Kaohsiung, Taiwan, China by Bohan Wu, Shuang Zhao, Yuxiang Liu, Chunyan Zhang

“…Meteorological variables are key determinants of air quality; however, research on their impact across different urban gradients remains limited, and their mechanisms are largely unexplored. This study investigates the dynamic effects of meteorological variables on air quality under varying levels of urbanization using Kaohsiung City, Taiwan, as a case study. …”
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Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway by Xin Ma, Meng Li, Yuanyuan Zhang, Tingting Xu, Xinchen Zhou, Mengqi Qian, Zhiren Yang, Xinyan Han

“…We used piglet, mouse, and intestinal organoid models to explore the protective effects and mechanisms of FMT on ETEC infection. The results showed that FMT regulated gut microbiota and enhanced the protection of AIMD piglets against ETEC K88 challenge, as demonstrated by reduced intestinal pathogen colonization and alleviated gut barrier injury. …”
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Protein palmitoylation is involved in regulating mouse sperm motility via the signals of calcium, protein tyrosine phosphorylation and reactive oxygen species by Yuping Xiong, Chenchen Yi, Haixia Zheng, Ya Ni, Yamei Xue, Kun Li

“…This study aimed to elucidate the mechanism by which protein palmitoylation governs sperm motility. …”
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Immune responses in rodent whole eye transplantation: elucidation and preliminary investigations into rejection diagnosis and monitoring by Bing Li, Yong Wang, Charles R. Owens, Touka Banaee, Charleen T. Chu, Kayvon Jabbari, Anna D. Lee, Neil J. Khatter, Alan G. Palestine, An-Jey A. Su, Christene A. Huang, Kia M. Washington

“…Additionally, corneal transparency grading proved effective as a non-invasive monitoring tool.ConclusionThis study offers a first-time comprehensive exploration of immune responses in WET, unveiling rapid and complex rejection mechanisms. The identification of early biomarkers and the development of non-invasive monitoring techniques significantly advance our understanding of WET rejection. …”
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Comparison Of Glucagon Like Peptide/1 Levels In Diabetic Women With Ovarian Polycystic Syndrome And Healthy Women by Namra Iqtidar, Imran Ali Zaidi, Sobia Niaz, Javaria Latif, Amir Naveed, Ayesha Yousaf

“…The main function of GLP-1 is the reduction of glucose blood levels during hyper-glycemia through the mechanism of increased secretion of hormone insulin and reduced glucagon hormone secretion. …”
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