Knockdown of Adra2a Increases Secretion of Growth Factors and Wound Healing Ability in Diabetic Adipose-Derived Stem Cells by Xiangyuan Zhao, Yong Zhang, Xinzhen Zuo, Shubai Wang, Xiao Dong

“…Studies showed that compared to normal adipose-derived stem cells (ASCs), ASCs from type 2 diabetic (T2D) mice were less effective in treating diabetic cutaneous wounds. However, the mechanisms remain unclear. Our transcriptomic profiling comparison showed that the expression of α2A-adrenergic receptor (Adra2a) was significantly increased in ASCs from T2D mice (T2D ASCs). …”
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A Cause Analysis of the High-Content Nitrogen and Low-Content Hydrocarbon in Shale Gas: A Case Study of the Early Cambrian in Xiuwu Basin, Yangtze Region by Yizhou Huang, Kun Zhang, Zhenxue Jiang, Yan Song, Shu Jiang, Chengzao Jia, Weiwei Liu, Ming Wen, Xuelian Xie, Tianlin Liu, Xin Li, Xin Wang, Xiaoxue Liu, Ye Zhang, Ling Tang

“…The study of nitrogen concentration in shale gas contributes to solve the question that how shale gas diffuses in complex tectonic areas, which helps to figure out the preservation requirements and accumulation mechanisms of shale gas and avoid exploration crisis. …”
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The Effects Of Simvastatin On Islets Of Langerhans In The Pancreas Of Rats: A Histological And Biochemical Study by Abdullah Qamar, Hammad Gul Khan, Hina Kundi, Ayesha Ali, Sumyyia Bashir, Tooba Khurshid

“…Further research is necessary to elucidate the underlying mechanisms and clinical implications of these observations. …”
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Impacts of tropical climate on outdoor treatment of anaerobically digested sanitary wastewater using native microalgae by Gabriela Santos Cardozo, Graziele Ruas, Fabiana Alves Fiore, Gustavo Henrique Ribeiro Silva

“…Cultivation was performed on a bench scale using anaerobically digested sanitary wastewater processed by two mechanisms from the wastewater treatment plant in Bauru, Brazil: the Upflow Anaerobic Filter (UAF) and the Anaerobic Baffled Reactor (ABR). …”
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Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review by Brijesh Singh Chauhan, Yash Pal Singh

“…Results: We conducted a comprehensive review of the research progress on ANE, focusing on its pharmacological effects on various diseases using animal models, mechanisms of action, and composition, are as not explored in preceding reviews. …”
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Characterization of Two Historical Postage Stamps Made from Cotton Fibers and Their Restoration Trials Based on the Experimental Studies by Maisa M.A. Mansour, Yassin E. Zidan, Abou El Fettouh A Abd El Hakim, Mohamed Mahmoud Allam, Hayssam M. Ali, Mohammad Akrami, Mohamed Z. M. Salem

“…Two Egyptian historical postage stamps printed in blue and red printing inks were evaluated and examined for their composition using a light microscope, SEM-EDS, FTIR, and Raman spectroscopic analyses. Mechanical, chemical, and deacidification treatments were done for the two stamps. …”
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

“…IntroductionMetastasis is the major cause of thyroid cancer morbidity and mortality. However, the mechanisms are still poorly understood. MethodsWe performed genome-wide transcriptome analysis comparing gene expression profile of metastatic thyroid cancer cells (Met) with primary tumor cells established from transgenic mouse models of papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), poorly differentiated thyroid cancer (PDTC), and anaplastic thyroid cancer (ATC).ResultsGenes involved in tumor microenvironment (TME), inflammation, and immune escape were significantly overexpressed in Met cells. …”
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Kalmyks of the Salsky district in the context of national politics and ethno-social processes in the 1920s by Anton Viktorovich Averyanov

“…The purpose of the article is to identify the features of ethno social relations in the Salsky district during the NEP period, to identify and analyze the key mechanisms of socio-political and economic integration of the Kalmyk population. …”
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Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. Early detection of IBD is paramount for arresting disease progression and underscoring the importance of prognostic testing and genetic screening, especially in cases with familial predispositions or very early onset IBD. …”
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Introduction of the Project “Community Police Officer” as a Step towards Strengthening Local Security Infrastructure by O. I. Bezpalova

“…The author has emphasized on the importance of developing Regulations on the organization of community police officers’ work and developing an effective mechanism for elaborating the training programs for community police officers.…”
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Impact of Resistance Exercise under Hypoxia on Postexercise Hemodynamics in Healthy Young Males by Masahiro Horiuchi, Arisa Ni-i-nou, Mitsuhiro Miyazaki, Daisuke Ando, Katsuhiro Koyama

“…Moreover, the underlying mechanisms for the attenuation of hypotension after resistance exercise may differ between normoxia and hypoxia.…”
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Development of binder based on phosphogypsum hardening by mixed type by T. А. Bakhtina, N. V. Lyubomirskiy, A. S. Bakhtin, G. R. Bilenko, I. A. Tyunyukov

“…The determination of the mechanical characteristics of the prototypes was carried out on the basis of the MCC8 control console (Controls).Results. …”
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PALATE FRACTURE PROFILE IN PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY OF DR. SOETOMO GENERAL ACADEMIC HOSPITAL: JANUARY 2012- DECEMBER 2017 by Priscilla Valentine N., Agus Santoso Budi, Lobredia Zarasade

“…The variables studied were demographic data including sex, age, mechanism of occurrence of accidents, types of fractures, management, complications that occur and length of treatment. …”
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Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…Abstract Background Vimentin is a type III intermediate filament protein that plays an important role in cytoskeletal mechanics. It is now known that vimentin also has distinct functions outside the cell. …”
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Nutritional Indices, Phytochemistry, and the In Vitro Antioxidant Activity of Carrot Fortified Tomato Concentrate by Olabisi Theresa Ademosun, Abiodun Humphrey Adebayo, Kolawole Oluseyi Ajanaku

“…The plant materials were sourced locally, dried to a uniform weight, and milled using a mechanical blender. Nutritional indices, viz., proximate analysis, were analyzed using a standard protocol. …”
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Fatty acid metabolism-related signature suggests an oncogenic role of TEKT1 in endometrial cancer by Zhikai Xiahou, Hong Xiao, Yafeng Song, Xin Xu

“…Co-immunoprecipitation and Western blot were performed to determine the mechanism of TEKT1. Results: A prognostic signature based on 10 FAMRGs (ACACB, PTGIS, BMPR1B, DHCR24, FAAH, GPX1, GPX4, INMT, PON3, PPT2) was generated using Lasso Cox hazards regression analysis in TCGA. …”
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Instability Mode and Control Technology of Surrounding Rock in Composite Roof Coal Roadway under Multiple Dynamic Pressure Disturbances by Peng Wang, Nong Zhang, Jiaguang Kan, Xingliang Xu, Guangzhen Cui

“…The progressive crack development characteristics in composite roof coal roadway and the instability failure mode of surrounding rock under multiple dynamic pressure disturbances were revealed, and the control mechanism and support scheme were put forward. According to the result, it is difficult to form a stable bearing rock beam due to the occurrence characteristics of the weak interlayer of the composite roof. …”
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DNA Methylation May be Involved in the Analgesic Effect of Hyperbaric Oxygen via Regulating FUNDC1 by Kun Liu, Hao Wu, Rui Gao, Guang Han

“…Pain-related behaviors were evaluated using mechanical withdrawal threshold and thermal withdrawal latency analysis. …”
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Exploitation of the genetic potential of <i>Thinopyrum</i> and <i>Agropyron</i> genera to protect wheat from diseases and environmental stresses by L. Ya. Plotnikova, V. V. Knaub

“…Wheat samples with the tall wheatgrass genes Lr19, Lr38, Sr24, Sr25 and Sr26 showed defence mechanisms similar to nonhosts resistance. Their influence led to disruption of the development of surface infection structures and fungal death when trying to penetrate the stomata (prehaustorial resistance or stomatal immunity). …”
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Extrapolating empirical measurements of wastewater exfiltration from sanitary sewers to estimate watershed-scale fecal pollution loading in urban stormwater runoff by Joshua A. Steele, Adriana González-Fernández, John F. Griffith, Darcy Ebentier McCargar, Sierra Wallace, Kenneth C. Schiff

“…Future work is needed to better understand subsurface transport mechanisms of exfiltrated sewage and to test this approach, and the assumptions used, in other watersheds and sewer systems.…”
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