Enucleated bone marrow-derived mesenchymal stromal cells regulate immune microenvironment and promote testosterone production through efferocytosis by Lu Sun, Jiayu Huang, Xuezi Wang, Peng Huang, Baolin Dong, Zehang Liang, Jiahong Wu, Jiancheng Wang

“…Testosterone production and spermatogenesis were detected at different time points through various tests. To determine the mechanism of efferocytosis, we analysed the number of macrophages by immunofluorescence staining and quantitative real-time polymerase chain reaction (qRT-PCR). …”
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Genetic Mapping for Seed Aging Tolerance Under Multiple Environments in Sweet Corn by Yanchao Du, Jianting Lin, Haoxuan Jiang, Huating Zhao, Xuebiao Zhang, Ruigang Wang, Faqiang Feng

“…This study provides a foundational understanding of the genetic mechanisms of seed aging tolerance and the innovation of an elite germplasm for seed aging tolerance in sweet corn.…”
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GOVERNMENT DEBTS AND ECONOMIC GROWTH NEXUS: EMPIRICAL EVIDENCE FROM EMERGING ECONOMY by Emmanuel Imuede OYASOR

“…This could include refinancing existing high-cost debt with lower-interest options, optimizing the debt maturity structure, and improving credit ratings through sound fiscal policies and economic reforms, regulate the issuance and management of domestic debt to ensure it is used efficiently and does not crowd out private sector investment, also, ensure that both foreign and domestic debt are allocated to projects and sectors with high growth potential, and establish mechanisms for regular monitoring and evaluation of public debt levels and their impact on economic growth. …”
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CRISPR/Cas9, a universal tool for genomic engineering by A. V. Smirnov, A. M. Yunusova, V. A. Lukyanchikova, N. R. Battulin

“…First, we describe the basic mechanism of the CRISPR/Cas9 DNA recognition and binding, focusing in particular on its off-target activity. …”
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DKK3 promotes renal fibrosis by increasing MFF-mediated mitochondrial dysfunction in Wnt/β-catenin pathway-dependent manner by Jianling Song, Yanxia Chen, Yan Chen, Minzi Qiu, Wenliu Xiang, Ben Ke, Xiangdong Fang

“…However, the underlying mechanisms of DKK3 in CKD are not fully understood.Methods H2O2-treated HK-2 cells and ureteric obstruction (UUO) mice were used as RF models. …”
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Long time-series and high-frequency ecological evaluation of Henan section of the Yellow River by Jianzhong Guo, Daozhu Xu, Jian Xu, Ruoxin Zhu, Ning Li

“…However, due to the limitations of the existing model's solution mechanism, current ecological environment assessment models have poor automation capabilities. …”
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Screening of <em>FecLL</em> prolific allele of the <em>B4GALNT2</em> gene in Algerian sheep populations by Assia Hadjazi, Fatima Zahra Belharfi, Fatima Zohra Mahammi, Stéphane Fabre, Semir Bechir Suheil Gaouar, Nacera Tabet-Aoul

“… Background: Research on the main genes controlling prolificacy in sheep, also known as fecundity genes (Fec genes), has highlighted the mechanisms involved in ewe fertility and the genetic improvement of prolificacy. …”
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MicroRNA-26b inhibits cardiac remodeling after myocardial infarction by targeting ring finger protein 6 expression by Chun-Mei Tang, Qiang Su, Hai-Xia Zhao, He-Huan Sui, Jing Liang, Li-Sha Zhu, Si-Yun Yang, Tao Liu

“…Introduction This study aimed to determine the regulatory mechanism of miR-26b in myocardial infarction (MI)-induced cardiac remodeling through apoptosis. …”
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The experience of bodily image for patients with left ventricular assist device by Irena Milaniak, Emilia Witkowska, Marta Cebula, Paulina Tomsia, Grzegorz Wasilewski, Izabela Górkiewicz-Kot, Sylwia Wiśniowska-Śmiałek, Michał Kaleta, Karol Wierzbicki, Karol Wierzbicki

“…IntroductionMechanical Cardiac Support and Left Ventricular Assist Devices (LVAD) have been demonstrated to prolong Heart Failure patients' survival and improve their quality of life. …”
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Incorporation of kiwifruit peel improved the property of carboxymethyl cellulose-gum Arabic active film and its effects on the quality of beef sausages by Evans Frimpong Boateng, Ziyi Yang, Jian Zhang, Lei Zhou, Lujuan Xing, Wangang Zhang

“…CG-KPE films exhibited better physical and mechanical properties, increased opacity, and better ultraviolet (UV) emission barrier due to KPE addition and pigmentation compared to CG-CT films. …”
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Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein by Paula Andréa Malveira Cavalcante, Natalia Alenina, Alexandre Budu, Leandro Ceotto Freitas-Lima, Thaís Alves-Silva, Juan Sebastian Henao Agudelo, Fatimunnisa Qadri, Niels Olsen Saraiva Camara, Michael Bader, Ronaldo Carvalho Araújo

“…Macrophages contribute to a continuous increase in blood pressure and kidney damage in hypertension, but their polarization status and the underlying mechanisms have not been clarified. This study revealed an important role for M2 macrophages and the YM1/Chi3l3 protein in hypertensive nephropathy in a mouse model of hypertension. …”
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State-of-the-art gene therapy for inherited retinal disorders by O.I. Orenburkina, A.E. Babushkin

“…Babushkin² </p> <p> ¹Russian Center for Eye and Plastic Surgery of the Bashkir State Medical University, Ufa, Russian Federation </p> <p> ²Ufa Research Institute of Eye Diseases of the Bashkir State Medical University, Ufa, Russian Federation </p> <p> Inherited retinal diseases (IRDs), which are orphan diseases, are a relevant social issue due to severe visual impairment and disability in children and working-age individuals. …”
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Disruption of the CRF1 receptor eliminates morphine-induced sociability deficits and firing of oxytocinergic neurons in male mice by Alessandro Piccin, Anne-Emilie Allain, Jérôme M Baufreton, Sandrine S Bertrand, Angelo Contarino

“…Substance-induced social behavior deficits dramatically worsen the clinical outcome of substance use disorders; yet, the underlying mechanisms remain poorly understood. Herein, we investigated the role for the corticotropin-releasing factor receptor 1 (CRF1) in the acute sociability deficits induced by morphine and the related activity of oxytocin (OXY)- and arginine-vasopressin (AVP)-expressing neurons of the paraventricular nucleus of the hypothalamus (PVN). …”
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Height development and multiple bone health indicators in children aged 2-12 years with Duchenne muscular dystrophy (DMD). by Bingying Wang, Linyuhan Zhou, Shuangru Li, Huayan Xu, Yingkun Guo, Qin Hu, Min Huang, Dan Zhou, Xiaotang Cai, Qiu Wang, Xiaomei Sun

“…<h4>Purpose</h4>To establish the height growth curve of early DMD, and evaluate the potential influencing markers on height growth, provide further evidence for pathological mechanism, height growth management and bone health in DMD.…”
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Ecolinguistic dynamics of English loanwords in Chinese: a case study on terms for cement by Ruifeng Mo, Hao-Zhang Xiao

“…This study examines five cement-related English loanwords in Chinese to uncover the evolutionary mechanisms governing the adaptation of these loanwords by analyzing their ecological dynamics. …”
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Genome-wide quantification of polycistronic transcription in Leishmania major by Janne Grünebast, Stephan Lorenzen, Joachim Clos

“…Lastly, we find evidence for transcriptional pausing of all three RNA polymerase classes, hinting at a possible mechanism of transcriptional regulation.IMPORTANCELeishmania spp. are pathogens of humans and animals and cause one of the most important neglected tropical diseases. …”
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Cell-free DNA release following psychosocial and physical stress in women and men by A. S. Limberg, F. Berg, E. Köper, C. Lindgraf, C. Gevers, R. Kumsta, E. M. Hummel, D. A. Moser

“…However, further research is necessary to elucidate the mechanisms of cfDNA release from specific cells and to understand its biological function in the body.…”
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Early measures for prevention and containment of COVID-19 in the Maldives: A descriptive analysis by Mariyam SUZANA, Sheena MOOSA, Fathmath Nazla RAFEEG, Sofoora K. USMAN

“…Unlike many countries, which imposed restrictions for weeks at a stretch, Maldives applied a strategy of gradual in- tensification of measures, imposed localized restrictive measures compared to a national lockdown and used multiple communication mechanisms to educate and engage the community. The public-private partner- ships explored were strategic in mitigating the loss of income to the tourist industry as well as in breaking the chain of transmission. …”
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Neuron-Specific Glycine Metabolism Links Transfer RNA Epitranscriptomic Regulation to Complex Behaviors by Jennifer Blaze, Viviana Dolores Evans, Jessica Abigail Feria Pliego, Petr Unichenko, Behnam Javidfar, Soeren Heissel, Hanan Alwaseem, Zachary Pennington, Denise Cai, Henrik Molina, Christian Henneberger, Schahram Akbarian

“…Background: The presence of treatment resistance in neuropsychiatric disease suggests that novel mechanism-based discoveries and therapies could benefit the field, with a viable candidate being transfer RNA (tRNA) epitranscriptomics. …”
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A hybrid ice-mélange model based on particle and continuum methods by S. Kahl, C. Mehlmann, D. Notz

“…<p>Ice mélange, a composite of sea ice and icebergs, can have a major influence on sea-ice–ocean interactions. However, ice mélange has not been represented in climate models because numerically efficient realizations do not exist. …”
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