DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences by Gaëlle Lenglet, Marie-Hélène David-Cordonnier

“…Small DNA-interacting molecules share the ability of certain proteins to change the DNA helix's overall organization and geometrical orientation via tilt, roll, twist, slip, and flip effects. In this ocean of DNA-interacting compounds, most stabilize both DNA strands and very few display helix-destabilizing properties. …”
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Methods for Increasing Power Efficiency of Heating Furnaces Applied in Metallurgical and Mechanical Engineering Industries by M. L. German, S. M. Kabishov, A. A. Oznobishin

“…The paper analyzes experimental data and results of balance tests of two continuous heating furnaces applied in mechanical engineering and metallurgical industries. …”
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Performance analysis and optimization for coverage classes updating mechanism of narrow-band internet of things by Xin JIAN, Yuqin LIU, Yixiao WEI, Jian SONG, Fang WANG, Shu FU, Xiaoheng TAN

“…A Markov chain model with coverage classes as state variables was established to describe the dynamics of the coverage classes updating mechanism of narrow-band internet of things (NB-IoT).An optimization model to minimize average probability of access failure as well as average power consumption was formulated,with which the effects of preamble repetition number,system load and global maximum transmission number on the optimal configuration of maximum transmission number of each coverage class was analyzed.Numerical analysis results show that the maximum transmission number of normal coverage and extended coverage have a great influence on the system performance and their value ranges should be set within[1,5]and[1,7]respectively.However,the maximum transmission number of extreme coverage has little influence on the system performance,its value could be any one in[1,10]but the recommended value is 1.In addition,the average power consumption of the model that introduced coverage classes’ rollback mechanism is about 95% lower than the model proposed by 3GPP.…”
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Study on the improvement of behavior and pain and the mechanism of Yangpafang in subacute Parkinson's disease model mice by SHI Ying, MEI Shan‐shan, WANG Yuan‐ling, XIA A‐long, WANG Xiao‐wei, LI Jun

Subjects: “…behavior and behavior mechanisms…”
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Effect of Curing Methods on the Mechanical Properties of Cement Mortar Contaminated with Heavy Crude Oil by Rajab Abousnina, Fahad Aljuaydi

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Cross-domain multi-copy of flow discovery mechanism based on dual certificate storage by Haiyang LUO, Bin KUANG, Shoukun GUO, Lingcui ZHANG, Ben NIU, Fenghua LI

“…To solve the problems of the privacy information leakage caused by the deliberate or inadvertent retention of information when information was frequently exchanged across nodes and systems in a ubiquitous sharing environment, a cross-domain multi-copy of flow discovery mechanism based on dual certificate storage was proposed, which could trace the propagation path and channel, and construct a multi-copy propagation graph of the information.Depending on the timing and method of certification, the dual certification was comprised active circulation certification and passive operation certification.Before the information was shared, the information sharer actively recorded the propagation path and method to generate active circulation certification records.Before the information was operated, the system automatically recorded the propagation path to generate passive operational certification records.Compared with single certificate storage, the dual certificate storage could improve the integrity and authenticity of the constructed multi-copy propagation graph of information, and could detect nodes with abnormal certificate storage behavior and provide disposals.Based on the theory of social punishment, the effectiveness of abnormal certificate storage behavior detection and handling was demonstrated.A prototype system for multi-copy discovery of OFD with dual certificate storage is developed, the improvement of information dissemination graph construction integrity by the proposed mechanism is verified.…”
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Corrosion Mechanism of Press-Hardened Steel with Aluminum-Silicon Coating in Controlled Atmospheric Conditions by Nikola Macháčková, Darja Rudomilova, Tomáš Prošek, Thierry Sturel, Maxime Brossard

“…The effect of various atmospheric parameters on the corrosion mechanism of press-hardened steel (PHS) coated with Al-Si (AS) was studied. …”
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Overlap of Functional Gastrointestinal Disorders: Common Mechanisms of Pathogenesis as a Key to Rational Therapy by S. N. Mekhdiyev, O. A. Mekhdieva, O. M. Berko

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Anti-fatigue activity and mechanism of crocetin loaded nanoliposome in acute exercise-treated mice by Jian Nan, Jinglei Li, Haishan Wu, Haoran Cheng, HyunJin Park, Qingsheng Zhao, Liu Yang

“…In the present study, the antifatigue activities and potential mechanism of crocetin loaded nanoliposome (CLN) was extensively investigated. …”
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Numerical Simulation of Mechanical Characteristics of Roadway Surrounding Rock under Dynamic and Static Loading by Ce Jia, Sheng Li, Chaojun Fan, Jinbao Tang

“…Mechanical characteristics of roadway surrounding rock under different stress wave disturbances are the key to design roadway supporting scheme. …”
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Error Analysis and Compensation of a Three-degree-of-freedom Cervical Traction Rehabilitation Mechanisms by Hong Li, Qingfeng Wang, Xinyu Wang, Weixiao Lu

Subjects: “…Cervical traction rehabilitation mechanisms…”
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Deciphering the pseudouridine nucleobase modification in human diseases: From molecular mechanisms to clinical perspectives by Shiheng Jia, Xue Yu, Na Deng, Chen Zheng, Mingguang Ju, Fanglin Wang, Yixiao Zhang, Ziming Gao, Yanshu Li, Heng Zhou, Kai Li

“…This review examines the regulatory mechanisms and pathological implications of pseudouridylation in human diseases, with a focus on its involvement in tumourigenesis. …”
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Workspace Analysis of a 2PRS/2PUS 4-DOF Parallel Mechanism by Pu Zhixin, Jin Lei

Subjects: “…Parallel mechanism…”
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Mechanical Properties of Hemp Fiber-Reinforced Polypropylene Composites for Drone Propeller Guard Application by Witawat Singsang, Thanasak Khamsin, Chayapol Prachumchon, Anurak Rodbumrung, Benjamas Netiworaruksa, Natkrita Prasoetsopha, Ing-orn Sittitanadol

“…Mechanics of Advanced Composite Structures…”
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Efficient handover authentication and secure key-updating mechanism for B5G networks by Qimei CUI, Wenjing ZHAO, Xiaoyang GU, Zengbao ZHU, Xiaoxuan ZHU, Xiaofeng TAO, Wei NI

“…In order to solve the problems of 5G network handover authentication and key update mechanism， such as lacking of forward security， being vulnerable to bypass attack and having signaling congestion， for 5G enhanced （B5G） network， an efficient handover authentication and security key-updating mechanism based on no certificate was proposed.The certificateless key agreement mechanism was introduced in the network edge side， which made the mobile terminals in-itiate the key-updating request actively and complete the whole certificateless key-updating process on the fly.The security of the key-updating mechanism was proved theoretically based on the Diffie-Hellman problem under the eCK security model.Simulation results demonstrate that the proposed mechanism not only meets the forward security of mobile terminal key management， but also has lower communication and computing overheads compared with other similar handoff authentication.…”
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Evaluating the Mechanisms of Improved Glucose Homeostasis after Bariatric Surgery in Ossabaw Miniature Swine by Jonathan G. Sham, Vlad V. Simianu, Andrew S. Wright, Skye D. Stewart, Mouhamad Alloosh, Michael Sturek, David E. Cummings, David R. Flum

“…Roux-en-Y gastric bypass (RYGB) is the most common bariatric operation; however, the mechanism underlying the profound weight-independent effects on glucose homeostasis remains unclear. …”
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Failure Mechanism of Salt Barrier in Saline Soil Subgrade in Cold and Arid Plateau Areas by Yurong Zhang, Wen Zhang, Yanbin Fan, Shiyi Liu, Yunxiu He, Yi Zou

“…In addition, their water and salt transport heights and the failure mechanism of the subgrade salt barrier were studied. …”
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Mobile Internet of Things Dynamic Grid QoS Service Matching Mechanism and Simulation Analysis by Xuemei Fan

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Sealing Form and Failure Mechanism of Deep In Situ Rock Core Pressure-Maintaining Controller by Nianhan Wu, Heping Xie, Ling Chen, Mingzhong Gao, Cong Li

“…The mechanical properties of deep rocks change nonlinearly in an in situ pressure environment, so standard cores cannot be used as real samples for deep rock mechanics research. …”
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Crushing Stones: Mechanical, Intracorporeal and Extracorporeal Lithotripsy in the Clearance of Common Bile Duct Lithiasis by Claude Liguory, Jean Francois Lefebevre, Didier Bonnel, Gary C Vitale

“…Mechanical lithotripsy was performed in 74 cases and was successful in 38 (51.3%). …”
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