China’s peacekeeping activities within the UN: Features, challenges, and prospects by Qian Li

“…The author emphasizes that China is not only actively engaging into the existing UN peace-keeping mechanisms and initiatives, but also offers its own original conceptual approaches to address the challenges related to peacemaking and peacebuilding. …”
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A Simple Approach for Mitigating a New Flooding Attack in RPL-Based IoT Networks by Mehdi Rouissat, Ibrahim S. Alsukayti, Mohammed Belkheir, Mohammed Alreshoodi, Allel Mokaddem, Djamila Ziani

“…The inherent design of RPL, particularly its topology establishment and maintenance mechanism, makes it easy to initiate more damaging attacks such as flooding attacks. …”
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A Novel Approach for Monitoring the Ecoenvironment of Alpine Wetlands using Big Geospatial Data and Cloud Computing by Haijun Wang, Xiangdong Kong, Ji Luo, Pengju Li, Tianhui Xie, Xiaobo Yi, Fang Wang, Jie Xiao

“…However, due to the limitations of data sources and calculation models, it is impossible for us to deeply understand the change mechanism and spatial difference of the ecological environment of the alpine wetland (EEAW) in previous studies. …”
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The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…This study focused on exosomes derived from stem cells of human exfoliated deciduous teeth (SHED-MSC-EXOs) and their role in managing the balance of immunoregulatory macromolecules that play a role in the underlying immunoregulatory mechanisms in THP-1-derived M0/M1 macrophage cells.MethodsFlow cytometry confirmed the expression of CD14, CD68, CD80, and CD86 markers in these macrophages. …”
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Antinociceptive and Anti-Inflammatory Activities of Teucrium persicum Boiss. Extract in Mice by Abdolhossein Miri, Javad Sharifi-Rad, Kaveh Tabrizian, Ali Akbar Nasiri

“…These results suggest that the aqueous extract from T. persicum Boiss. produced antinociceptive effects. Its exact mechanism of action still remains indistinct.…”
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Candidate genes for productivity identified by genome-wide association study with indicators of class in the Russian meat merino sheep breed by A. Y. Krivoruchko, O. A. Yatsyk, E. Y. Safaryan

“…However, further research is needed to confirm the influence of genes and determine the exact mechanisms for implementing this influence on the phenotype.…”
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Atg5 deficiency in basophils improves metabolism in lupus mice by regulating gut microbiota dysbiosis by Jiaxuan Chen, Quanren Pan, Lu Lu, Xiaorong Huang, Shuting Wang, Xiaoxian Liu, Jiaqi Lun, Xiaowei Xu, Hongyong Su, Fengbiao Guo, Lawei Yang, Liuyong You, Haiyan Xiao, Wenying Luo, Hua-feng Liu, Qingjun Pan

“…Emerging evidence shows that basophil activation plays a critical role in the pathogenesis of SLE; however, the underlying mechanisms remain largely unknown. Here, we investigated the effects of autophagic inhibition on the pathogenesis of basophils in SLE using Autophagy-related gene 5 (Atg5) knockout (Atg5 −/−) as an autophagic inhibitor. …”
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Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction by Hongjian Zhou, Zhipeng Xu, Chun Jiang, Qiuyue Wu, Chuanyue Zhang, Zhenyu Liu, Xiaoxue Zhang, Weiwei Li, Yujia Pang, Jing Zhang, Wenju Pan, Min Chen, Xinyi Xia

“…Abstract Introduction Ionizing radiation (IR) poses a significant threat to male fertility by inducing substantial changes in the testis, yet the mechanisms underlying IR-induced spermatogenesis disorders remain poorly understood, necessitating the development of more effective radioprotective agents. …”
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Trench MOS Schottky Diodes: A Physics-Based Analytical Model Approach to Charge Sharing by Mohammed Tanvir Quddus, Alvaro D. Latorre-Rey, Zeinab Ramezani, Mihir Mudholkar

“…Additionally, it provides a detailed view of the electric field suppression mechanism in the TMBS device, highlighting the significant effects of the inversion charge on the MOS interface. …”
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Exploring the anticancer potential of Hewittia malabarica through phytochemical analysis and molecular docking study by Shiji Thozhukkad Moosaripparambil, Kannan Vadakkadath Meethal

“…These results indicate that the mechanism of cytotoxicity observed may be mediated through induction of apoptosis in cancer cell lines. …”
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Natural Polymer Derivative-based pH responsive Nanoformulations Entrapped Diketo-tautomers of 5-fluorouracil for Enhanced Cancer Therapy by Anbazhagan Thirumalai, Koyeli Girigoswami, Karthick Harini, Venkatakrishnan Kiran, Pazhani Durgadevi, Agnishwar Girigoswami

“…Conclusion: In acidic conditions, there is a greater release of 5-FU than neutral pH levels, indicating a pH-responsive release profile beneficial for cancer treatment, with the release mechanism of OSANPs following Fickian diffusion as identified by a Korsmeyer-Peppas mathematical model and the formu¬lation showing improved therapeutic efficacy. …”
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Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism by Yoshimichi Takeda, Masashi Demura, Mitsuhiro Kometani, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Shin-ichi Horike, Makiko Meguro-Horike, Takashi Yoneda, Yoshiyu Takeda

“…HSD11B1 expression is partly controlled by an epigenetic mechanism in human tissues. The pathophysiological role of epigenetic regulation of HSD11B1 expression in adipose tissue requires further study.…”
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Balancing central control and sensory feedback produces adaptable and robust locomotor patterns in a spiking, neuromechanical model of the salamander spinal cord. by Alessandro Pazzaglia, Andrej Bicanski, Andrea Ferrario, Jonathan Arreguit, Dimitri Ryczko, Auke Ijspeert

“…The locomotor circuits, modeled as a spiking neural network of adaptive leaky integrate-and-fire neurons, are coupled to a three-dimensional mechanical model of a salamander with realistic physical parameters and simulated muscles. …”
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Therapeutic effects of Pueraria lobata (Willd.) Ohwi root and Hovenia dulcis Thunb. extracts on alcoholic liver disease: Network pharmacology and experimental validation by Zhendong Chen, Yu Yue, Hongyan An, Haisu Yan, Hyeok-Joo Park, Pei Lin

“…In addition, activation of the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) pathway was examined to elucidate the mechanisms underlying the effects of the extract. Results: Treatment with the extract contributed to a significant reduction in the release of nitric oxide and reactive oxygen species in the ethanol-treated HepG2 cells; promoted the elevated expression of superoxide dismutase, catalase, and glutathione, indicating enhanced antioxidant defenses; and showed strong free radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazyl radicals. …”
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A DNA-Methylated Sight on Autoimmune Inflammation Network across RA, pSS, and SLE by Xingqiang Wang, Dongyun Lei, Jie Ding, Shuang Liu, Li Tao, Fan Zhang, Jiangyun Peng, Jian Xu

“…Differentiating the cytokine methylation status will serve as valuable resource for researchers alike to gain better understanding of the epigenetic mechanisms of the three AIDs. Even more importantly, better understanding of cytokine methylation variability existing between the three classic AIDs will aid in identification of potential epigenetic biomarkers and therapeutic targets. …”
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Influences of multi-pass friction stir alloying on characterization of AZ91D alloy-based dual reinforcement bio-ceramic nano-composites by Surendra Kumar Patel, Guoxin Dai, Lu Liu, Zhen Sun, Lei Shi

“…In current study, microstructural, mechanical and corrosion behaviour were investigated with incorporation of dual reinforced AZ91D surface composites. …”
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Low-dose radiation ameliorates PM2.5-induced lung injury through non-canonical TLR1/TLR2-like receptor pathways modulated by Akkermansia muciniphila by Li Wang, Zhipeng Li, Huan He, Lijing Qin, Weiqiang Xu, Hongyuan Tian, Rongrong Liu, Xinru Lian, Wen Li, Yali Qi, Zhicheng Wang

“…Here, we aim to investigate the impact of LDR on PM2.5-induced lung injury in vivo and in vitro, and elucidated the potential mechanisms of anti-inflammation activated by gut microbiota. …”
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Static and dynamic experimental study of strengthened inforced short concrete corbel by using carbon fabrics, crack path in shear zone by I. Ivanova, J. Assih

“…The success of strengthening depends strongly on surface preparation conditions. The cracking mechanisms and collapse modes under static and dynamic loadings are presented. …”
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Comparison of the Effects of Desflurane, Sevoflurane, and Propofol on the Glottic Opening Area during Remifentanil-Based General Anesthesia Using a Supraglottic Airway Device by Takashi Kondo, Hiromichi Izumi, Makiko Kitagawa

“…Following induction of general anesthesia with remifentanil, continuous fiberoptic video recording around the glottis via an i-gel™ supraglottic device was started after establishing mechanical ventilation. Desflurane, sevoflurane, or propofol was administrated after video recording was started. …”
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The simulation of ELM control by the advanced divertor configuration in EAST by Y.L. Li, T.Y. Xia, Z.P. Luo, Q.Z. Yu, S.F. Mao, B. Gui, X.X. He, H.M. Qi, P.C. Xie, M.Y. Ye, the EAST team

“…To obtain the physical mechanism of ELM suppression, the numerical simulations are carried out using the BOUT++ turbulence model. …”
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