Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects by Cong Wang, Ting Jiang, Lvwang Ye, Mengyan Du, Fang Liu

“…Future research should explore the effects of different strains and doses, as well as the underlying mechanisms involved.…”
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Targeting protein synthesis pathways in MYC-amplified medulloblastoma by Devendra Kumar, Ranjana Kanchan, Nagendra K. Chaturvedi

“…Evidence strongly proposes that MYC/mTOR-driven tumorigenic signaling can predominantly control the translational machinery to elicit cooperative effects on increased cell proliferation, cell cycle progression, and genome dysregulation as a mechanism of cancer initiation. Several small molecule inhibitors of targeting MYC indirectly and mTOR signaling have been developed and used clinically with immunosuppressants and chemotherapy in multiple cancers. …”
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Tumor renal by Yarisdey Corrales Hernández, Noelia Castro Ladrón de Guevara

“…--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} </style> <!…”
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Habitat radiomics based on CT images to predict survival and immune status in hepatocellular carcinoma, a multi-cohort validation study by Kun Chen, Chunxiao Sui, Ziyang Wang, Zifan Liu, Lisha Qi, Xiaofeng Li

“…Ultimately, an immune status profiling was conducted based on bioinformatic analyses and multiplex immunohistochemistry (mIHC) assays to reveal the potential mechanisms. Results: A total of 4 habitats were segmented, and the corresponding habitat radiomic models were constructed based on each habitat and an integration of all the four habitats. …”
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Deep eutectic solvent-assisted carbon quantum dots from biomass Triticum aestivum: A fluorescent sensor for nanomolar detection of dual analytes mercury (Ⅱ) and glutathione by Shivam Khare, Neeraj Sohal, Mandeep Kaur, Banibrata Maity

“…The fluorescence quenching mechanism was confirmed by several photophysical parameters, such as average lifetime values, radiative rate constant (kr), non-radiative rate constant (knr) and others. …”
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Scrapie-Responsive Gene 1 Promotes Chondrogenic Differentiation of Umbilical Cord Mesenchymal Stem Cells via Wnt5a by Yuchuan Zhou, Tian Zheng, Lin Li, Yangfang Guo, Jiayu Xiao, Jin Wang, Zhiqin Du, Hui Gao, Weiwei Tang, Liusan Yang, Haiyan Hu, Xiaodan Wang, Mingyao Meng, Zongliu Hou

“…Herein, we explored the mechanism by which scrapie-responsive gene 1 (SCRG1), a candidate gene for cartilage regeneration promotion, regulates chondrogenic differentiation of MSCs. …”
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Prevalence and prognostic value of ventricular conduction delay in heart failure with preserved ejection fraction by Anouk Achten, Jerremy Weerts, Johan van Koll, Mohammed Ghossein, Sanne G.J. Mourmans, Arantxa Barandiarán Aizpurua, Antonius M.W. van Stipdonk, Kevin Vernooy, Frits W. Prinzen, Hans-Peter Brunner-La Rocca, Christian Knackstedt, Vanessa P.M. van Empel

“…Future efforts are needed to understand the mechanisms underlying the association of QRS duration and adverse outcomes, and to determine its clinical implications.…”
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Akkermansia muciniphila and its metabolite propionic acid maintains neuronal mitochondrial division and autophagy homeostasis during Alzheimer’s disease pathologic process via GPR4... by Zifan Wang, Cai Wang, Boyu Yuan, Li Liu, Haoming Zhang, Mingqiang Zhu, Hongxia Chai, Jie Peng, Yanhua Huang, Shuo Zhou, Juxiong Liu, Liyong Wu, Wei Wang

“…In order to further reveal the effects and the mechanisms of propionic acid on AD prevention, we systematically explored the effects of propionic acid administration on AD model mice and cultured hippocampal neuronal cells. …”
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Egfr Amplification Specific Gene Expression in Phyllodes Tumours of the Breast by Konstantin Agelopoulos, Christian Kersting, Eberhard Korsching, Hartmut Schmidt, Arno Kuijper, Christian August, Pia Wülfing, Joke Tio, Werner Boecker, Paul J. van Diest, Burkhard Brandt, Horst Buerger

“…Methods: In order to gain further insights into regulation mechanisms associated with egfr amplifications and EGFR expression in phyllodes tumours, we performed global gene expression analysis (Affymetrix A133.2) on a series of 10 phyllodes tumours, of these three with and seven without amplifications of an important regulatory repeat in intron 1 of egfr (CA-SSR I). …”
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Synthesis of Mg-, Al- and Mg/Al-date palm fronds modified biochars: characterization and investigations on phosphorus adsorption characteristics by Jellali, Salah, Hadroug, Samar, Al-Wardy, Malik, Hamdi, Helmi,  Al-Sabahi, Jamal, Bekri, Imene, Al-Raeesi, Ahmed, Hamdi, Wissem,  Jeguirim, Mejdi

“…The kinetic and isotherm experimental data modelling suggest that P recovery process was governed by both physical and chemical mechanisms. These P-loaded biochars have the potential to serve as promising fertilizers, offering a sustainable alternative to synthetic counterparts.…”
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THE RISK-ORIENTED APPROACH TO THE DEVELOPMENT OF CONTROL METHOD by P. S. Serenkov, V. L. Hurevich, M. R. Movlamov, A. S. Yetumya

“…For the entire range of sources of particular risks the results of studies of the mechanisms of their manifestation, the estimated degree of influence on the accuracy of the control of compliance of flame-retardant coating thickness requirements. …”
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Emergency contracting and the delivery of elective care services across the English National Health Service and independent sector during COVID-19: a descriptive analysis by Rocco Friebel, Michael Anderson, Laia Maynou, Jon Fistein

“…Most specialties, irrespective of sector or funding mechanisms, experienced a reduction in hospital admissions. …”
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BPZ inhibits early mouse embryonic development by disrupting maternal-to-zygotic transition and mitochondrial function by Zhiming Ding, Huilei Chen, Huiru Cheng, Caiyun Wu, Hongzhen Ruan, Bingjing Zhu, Ping Zhou, Zuying Xu, Huifen Xiang

“…This study investigates the impact of BPZ exposure on early mouse embryonic development alongside an exploration of the underlying mechanisms. The findings reveal that exposure to BPZ leads to a reduction in early embryo quality and hinders developmental progression. …”
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Effect of Moringa oleifera, Bacillus amyloliquefaciens, and Their Combination on Growth Performance, Digestive Enzymes, Immunity, and Microbiota in Nile Tilapia (Oreochromis niloti... by Mingxuan Guan, Junfeng Guan, Haotian Zhang, Dikuang Peng, Xiaotong Wen, Xiaoyong Zhang, Qing Pan

“…To exploit aquatic animals’ feed resources and functional ingredients and additives, this experiment investigated the effects (a 2 × 2 factorial trial) and mechanism of woody plants and probiotics on Nile tilapia. …”
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A retrospective analysis on maternal and neonatal outcomes in pSS/AITD pregnancies by Miaoguan Peng, Taizhen Luo, Xiaoshi Weng, Yanmei Dong, Yijuan Xie, Siqi Huang, Naifeng Liang, Shiyun Wen, Yaojie Zhai, Yingjun Xie, Yuyi Chen

“…Further exploration is essential to unravel the precise mechanisms through which AITD impacts fetal growth and to identify potential interventions to mitigate these effects.…”
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The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

“…This study contributes to the understanding of the pathogenicity and adaptation mechanisms that Salmonella employs to establish a successful infection in its host.…”
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Comparing low-cost activated carbon made from coffee waste and bagasse to remove heavy metals and methylene blue dye by Nahla. M. Salatein, Mahmoud Shaaban, Irene. S. Fahim

“…Kinetic studies were assessed using pseudo-first-order and pseudo-second-order models to clarify the potential copper adsorption mechanism, which indicated a more rapid adsorption rate on the adsorbent, with the pseudo-second-order model exhibiting an acceptable fit for all samples. …”
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Association between adult body shape index and serum levels of the anti-aging protein Klotho in adults: a population-based cross-sectional study of the NHANES from 2007 to 2016 by Li Gong, Jinghan Xu, Yiyang Zhuang, Liwei Zeng, Zhenfei Peng, Yuzhou Liu, Yinluan Huang, Yutian Chen, Fengyi Huang, Chunli Piao

“…Higher ABSI was associated with lower serum Klotho concentrations; however, this association did not seem to be significant in subjects with BMI ≥30 kg/m2.Further study is needed to verify the causality of this association and elucidate the underlying mechanisms.…”
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Effects of acteoside from Cistanche tubulosa on the plasma metabolome of cancer-related fatigue mice inoculated with colon cancer cells by Shilei Zhang, Fukai Gong, Jiali Liu, Shuping You, Tao Liu, Jianhua Yang, Junping Hu

“…ObjectiveTo elucidate the metabolic mechanisms by which acteoside (ACT) isolated from Cistanche tubulosa alleviates cancer-related fatigue (CRF) in a murine model of colon cancer with cachexia.MethodsBALB/c mice inoculated with C26 colon cancer cells were treated with paclitaxel (PTX, 10 mg/kg) and ACT (100 mg/kg) alone or in combination for 21 days. …”
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miR-223 and Chromogranin A Affect Inflammatory Immune Cell Activation in Liver Metastasis of Neuroendocrine Neoplasms by Lukas Geisler, Katharina Detjen, Teresa Hellberg, Marlene Kohlhepp, Carsten Grötzinger, Jana Knorr, Ines Eichhorn, Raphael Mohr, Theresa Holtmann, Bertram Wiedenmann, Frank Tacke, Christoph Roderburg, Alexander Wree

“…Our data hence provide initial insights into an immunoregulatory mechanism via miR-223 and CgA in NEN cells, as regulation of miR-223 in NEN may affect tumor-associated inflammation.…”
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