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35761
Effects of fiber engraving laser on metallurgical, surface topography, and corrosion properties of AZ80 magnesium-based alloy
Published 2025-01-01“…Surface modification with fiber lasers improves the biological and mechanical properties of biomaterials. Magnesium, a lightweight metal similar to natural bone, shows no toxicity and can aid in hard tissue recovery when implanted in the human body. …”
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35762
PlantReg: the reconstruction of links between transcription factor regulatory networks and biological processes under their control
Published 2025-01-01“…Thus, PlantReg is a convenient tool for generating hypotheses about the molecular mechanisms that control plant traits.…”
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35763
Study protocol: an observational study of distress, immune function and persistent pain in HIV
Published 2022-06-01“…The relationship between distress and pain is bidirectional, but the mechanisms by which distress exacerbates pain are unclear. …”
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35764
Hot and cold exposure triggers distinct transcriptional and behavioral responses in laboratory-inbred pond snails
Published 2025-01-01“…These findings contribute to our understanding of thermal biology and stress physiology in aquatic organisms, underscoring the importance of molecular mechanisms in shaping species' resilience in dynamic environments.…”
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35765
LncRNA TUG1 mitigates chronic kidney disease through miR-542-3p/HIF-1α/VEGF axis
Published 2025-01-01“…This study evaluated the impact of miR-542-3p and lncRNA TUG1 on renal fibrosis, along with the underlying regulatory mechanisms. Through in vitro tube formation assays, research demonstrated that knocking down lncRNA TUG1 may enhance angiogenesis and repair damaged endothelial cell-cell connections. …”
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35766
Identification of key chromium resistance genes in Cellulomonas using transcriptomics
Published 2025-02-01“…Our study showed theoretical importance by revealing the Cr(VI) reduction mechanism using chrome-resistant microorganisms.…”
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35767
An Updated Model Does Not Reveal Sex Differences in Patellofemoral Joint Stress during Running
Published 2022-12-01“…# Background Structure-specific loading may have implications in understanding the mechanisms of running related injury. As females demonstrate a prevalence of patellofemoral pain twice that of males, this may indicate differences in patellofemoral loads between males and females. …”
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35768
Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Advances in bioinformatics provide opportunities to elucidate the underlying mechanisms of PTSD. Methods RNA sequencing (RNA‐seq) datasets were retrieved from the Gene Expression Omnibus (GEO) database. …”
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35769
Timp2 loss-of-function mutation and TIMP2 treatment in a murine model of NSCLC: Modulation of immunosuppression and oncogenic signaling
Published 2025-03-01“…However, the demonstration of such anti-tumor activity and associated mechanisms using in vivo tumor models is lacking. The effects of a Timp2 functional mutation and administration of recombinant TIMP2 were examined in both orthotopic and heterotopic murine models of lung cancer using C57Bl/6 syngeneic Lewis Lung 2-luciferase 2 cells (LL2-Luc2) cells. …”
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35770
Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis...
Published 2023-12-01“…The reconstruction of gene networks describing the molecular mechanisms of interaction of aberrantly methylated genes with key participants of the extrinsic apoptosis pathway and their regulation by HCV proteins can provide important information when searching for pharmacological targets. …”
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35771
Metal-free production of natural blue colorants through anthocyanin–protein interactions
Published 2025-02-01“…Objectives: Our study aims to introduce a metal-free approach to achieve blue coloration in commonly distributed non-acylated 3-glucoside ACNs by exploring their interactions with proteins and unveiling the underlying mechanisms. Methods: Using human serum albumin (HSA) as a model protein, we investigated the structural influences of ACNs on their blue color generation using visible absorption spectroscopy, fluorescence quenching, and molecular simulations. …”
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35772
Zionism and Academic Hegemony: The Intersection of Power, Knowledge, and Suppression in the United States Universities
Published 2024-12-01“…This paper highlights the need for a deeper understanding of the mechanisms through which Zionism shapes the intellectual landscape in the U.S., reinforcing power structures that limit open debate and critical scholarship.…”
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35773
Liberties of the genome: insertions of mitochondrial DNA fragments into nuclear genome
Published 2024-09-01“…The integration of new mtDNA fragments into the nuclear genome occurs during double-strand DNA break repair through the non-homologous end joining mechanism. Along with evolutionarily stable “genetic fossils” that were integrated into the nuclear genome millions of years ago and are shared by many species, there are NUMTS that could be species-specific, polymorphic in a species, or “private”. …”
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35774
Jidoka-DT simulator programmed by hybridize XGboost-LSTM to evaluate helmets quality produced by Rice-Straw-alumina plastic dough to resist shocks and impenetrable
Published 2025-03-01“…LSTM is used to determine the helmet weakness zones (WZ) and XGboost classifies product parts according to physical and mechanical property. The standard dough should have a density of between 1.16 and 1.4 g/cm3. …”
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35775
Phenolic Compounds and Pharmacological Potential of <em>Lavandula angustifolia</em> Extracts for the Treatment of Neurodegenerative Diseases
Published 2025-01-01“…The search for neuroprotective compounds in lavender is driven by its traditional use for brain health, with antioxidant activity serving as a key mechanism in reducing oxidative stress and supporting cognitive function. …”
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35776
Plasma Metabolite Profiles of Healthy Volunteers after Administration of a Thai Herbal Formula for Dizziness
Published 2024-12-01“…These results highlight YHF20's potential for enhancing life quality through anti-inflammatory mechanisms. They offer a scientific basis for its traditional and anecdotal uses and suggest a novel approach to sleep quality improvement not previously documented. …”
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35777
Automatic assessment of nailfold capillaroscopy software: a pilot study
Published 2024-11-01“…For the calculation of 1 mm capillaries, an additional detection mechanism was designed. Results The results obtained under neural network training were compared to the results obtained in manual analysis. …”
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35778
BMI trajectories are associated with NAFLD and advanced fibrosis via aging-inflammation mediation
Published 2025-01-01“…Aging-inflammation may represent a distinct mechanism of sustained obesity to NAFLD, independent of IR.…”
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35779
Education as a Resource for the Formation of “Soft Power” in Working with Young Compatriots Living in the CIS countries
Published 2023-05-01“…Firstly, Russian-speaking compatriots are the demographic potential of Russia, and nowadays institutional mechanisms have been developed and implemented to facilitate the voluntary resettlement of compatriots living abroad to the Russian Federation. …”
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35780
Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like be...
Published 2024-07-01“…Analysis of the mechanisms underlying autism spectrum disorder (ASD) is an urgent task due to the everincreasing prevalence of this condition. …”
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