Impacts of coal fracture roughness and aperture on the seepage of injected water: An experimental study by Gang WANG, Xuechang CHEN, Hao CHEN, Qingming LONG, Yixin LIU

“…Through a deep exploration into the relationships of the fracture aperture and roughness with seepage rate, this study determines the key mechanisms underlying the impacts of the fracture aperture and roughness on water injection into coal seams. …”
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Validation of a delirium predictive model in patients admitted to surgical intensive care units: a multicentre prospective observational cohort study by Kaweesak Chittawatanarat, Onuma Chaiwat, Sirirat Mueankwan, Sunthiti Morakul, Pitchaya Dilokpattanamongkol, Chayanan Thanakiattiwibun, Arunotai Siriussawakul

“…Validation was performed of the previously developed delirium predictive model: age+(5×SOFA)+(15×benzodiazepine use)+(20×DM)+(20×mechanical ventilation)+(20×modified IQCODE>3.42).Results In all, 380 SICU patients were recruited. …”
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Rab21-Targeted Nano Drug Delivery System-Based FFPG for Efficient Paclitaxel Delivery to Inhibit Lung Cancer Progression by Jing Wang, Xueying Yan, Wenfei Wang, Shu Wang, Hongxiang Jiang, Xinhua Zhu, Zhehui Li, Defu Cai, Yonggang Xia

“…<b>Background/Objectives</b>: <i>Platycodon grandiflorus</i> (PG) has been widely researched as a conductant drug for the treatment of lung diseases by ancient and modern traditional Chinese medicine (TCM) practitioners. Inspired by the mechanism and our previous finding about fructans and fructooligosaccharides from <i>Platycodon grandiflorus</i> (FFPG), we developed a nano drug delivery system (NDDS) targeting lung cancer. …”
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The Influence of the Farming System and Forecrop on the Yield and Chemical and Health-Promoting Composition of Spring Wheat Grain by Elżbieta Harasim, Cezary A. Kwiatkowski, Jan Buczek

“…In the conventional system, mineral NPK fertilization and pesticides (herbicides, fungicide, insecticide, and retardant) were applied at the recommended rates for wheat. Mechanical weed control was also used (double harrowing). …”
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β-ecdysone/PLGA composite scaffolds promote skull defect healing in diabetic rat by Yicai Luo, Ziwei Wu, Yingjuan Zhang, Yang Qiao, Yinge Wei, Xuan Yan, Xiangyu Ma, Xianxian Huang, Xiaoxia Zhong, Zhimao Ye, Xinping Lu, Hongbing Liao

“…Simultaneously, the safety of the scaffolds in vivo was also evaluated.ResultsThe material characterization results indicated that, in comparison to the single-pore size scaffold, the composite scaffold exhibited superior porosity, swelling ratio, drug loading capacity, and mechanical properties. Additionally, the composite scaffolds showed appropriate degradation performance and sustained drug release profiles. …”
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Synthesis of novel magnesium ferrite Schiff base chitosan nanocomposite for efficient removal of pb(II) ions from aqueous media by Nada S. Al-Kadhi, Ehab A. Abdelrahman, Fowzia S. Alamro, Reem K. Shah, Fawaz A. Saad, Khalil ur Rehman

“…The nanocomposite exhibited outstanding performance as a nanoadsorbent for the efficient removal of Pb(II) ions from aqueous media through electrostatic attraction and complexation mechanisms, achieving a maximum adsorption capacity of 290.7 mg g-1. …”
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The Effects of C. lacerata on Insulin Resistance in Type 2 Diabetes Patients by Arim Choi, Jung Hye Kim, Hye-Kyung Chung, Chul Woo Ahn, Hee Joon Choi, Yu-Sik Kim, Ji Sun Nam

“…A larger population study with a longer follow-up period and an effort to elucidate the mechanism is warranted to further assess the effects of C. lacerata on T2DM patients.…”
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Roof collapse accumulation and stress evolution characteristics of double-inclined mining in steeply inclined medium-thick coal seam by WU Yongping, XU Yingrui, XIE Panshi, WANG Hongwei, LANG Ding, HUANGFU Jingyu, QIANG Xubo, DU Yuqian, WANG Lechen, RU Xiaohui, WANG Zhengfu

“…The pseudo-inclined mining has limited capacity to reduce the inclination angle of working face, necessitating breakthroughs in longwall comprehensive mechanized mining methods for steeply inclined medium-thick coal seam with inclination angles exceeding 60°. …”
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Selective Vulnerability of the Cochlear Basal Turn to Acrylonitrile and Noise by B. Pouyatos, C. A. Gearhart, A. Nelson-Miller, S. Fulton, L. D. Fechter

“…Exposure to acrylonitrile, a high-production industrial chemical, can promote noise-induced hearing loss (NIHL) in the rat even though this agent does not itself produce permanent hearing loss. The mechanism by which acrylonitrile promotes NIHL includes oxidative stress as antioxidant drugs can partially protect the cochlea from acrylonitrile+noise. …”
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Production of abiotic or biogenic hydrocarbons on rock particles in the presence of H2O and carbon compounds by Young Sang Cho, In-Hwan Oh, Ju Hee Kim, Jae Ik Kim, Kang-Bong Lee, In Wook Nah

“…Here, we show that various rock constituents (solid acids) play a catalytic role in the formation of H and OH radicals via H2O dissociation, as well as in the formation of diverse hydrocarbons via the synthesis reactions of H radicals and inorganic carbons or by H radical-induced dissociation of organic carbons. The mechanisms and characteristics of these formation processes were explored through a series of reactor-based laboratory experiments. …”
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Microwave hyperthermia enhances radiosensitization by decreasing DNA repair efficiency and inducing oxidative stress in PC3 prostatic adenocarcinoma cells by Yajun Wu, Pengyuan Liu, Wendy Chen, Shiting Bai, Sisi Chen, Jianglin Chen, Xiaogang Xu, Jindan Xia, Yufei Wu, Jianjun Lai, Chuan Sun, Zhenghong Lao, Xiaoqing Wan, Zhibing Wu

“…In this study, we aimed to explore the use of microwave hyperthermia (MW-HT) to sensitize PCa to RT and investigate the underlying molecular mechanisms.Methods We developed a dedicated MW-HT heating setup, created an in vitro and in vivo MW-HT + RT treatment model for CRPC. …”
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Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma by Kawuli Jumai, Tangjuan Zhang, Bingzhang Qiao, Julaiti Ainiwaer, Haiping Zhang, Zhichao Hou, Idris Awut, Madinyat Niyaz, Liwei Zhang, Ilyar Sheyhidin

“…We further explored the cancer-promoting mechanism of target genes in ESCC by sequencing of the genes’ exons. …”
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Relationship between muscle activation and sagittal knee joint biomechanics in patients with patellofemoral pain syndrome: a cross-sectional study by Byung Sun Choi, Soon Bin Kwon, Sehyeon Jeon, Myeongjun Kim, Yunseo Ku, Du Hyun Ro, Hyuk-Soo Han

“…Conclusions Patients with PFPS exhibit elevated muscle activation, particularly in response to changes in the knee extension moment, which is likely a compensatory mechanism to manage knee joint loading during gait. …”
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Intrinsic constraint on T c for unconventional superconductivity by Qiong Qin, Yi-feng Yang

“…As a result, the known families of unconventional superconductivity, possibly except the infinite-layer nickelates, seem to almost exhaust their potentials in reaching the maximal T c allowed by their respective J, while achieving room temperature superconductor would require a much larger J beyond 400–700 meV, which seems unrealistic in existing correlated materials and hence demands novel pairing mechanisms. The agreement also implies some deep underlying principles of the constraint that urge for a more rigorous theoretical understanding.…”
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Precision Psychobiotics for Gut–Brain Axis Health: Advancing the Discovery Pipelines to Deliver Mechanistic Pathways and Proven Health Efficacy by Rebecca F. Slykerman, Naomi Davies, Klara Vlckova, Kenneth J. O'Riordan, Shalome A. Bassett, James Dekker, Harriët Schellekens, Niall P. Hyland, Gerard Clarke, Elaine Patterson

“…Expediting the transition from positive preclinical data to proven benefits in humans includes interpreting the promises and pitfalls of animal behavioural assays, as well as navigating mechanism‐informed decision making to select the right microbe(s) for the job. …”
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Combating modern methods of legalisation (laundering) of the funds obtained by criminal means with the use of cryptocurrency by V. Р. Yatsenko, V. S. Bushyn

“…The main shortcomings of the institutional and regulatory mechanism for detecting and investigating this category of offences have been highlighted, taking into account the use of modern financial technologies. …”
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Optimized scaffold-free human 3D adipose tissue organoid culture for obesity and disease modeling by Rafael Dariolli, Raphael Nir, Tova Mushlam, Glauco R. Souza, Stephen R. Farmer, Miguel L Batista, Jr.

“…However, existing adipose tissue models have limitations, particularly in the stable culture of fat cells that maintain physiologically relevant phenotypes, hindering a deeper understanding of adipocyte biology and the molecular mechanisms behind differentiation. Current model systems fail to fully replicate In vivo metabolism, posing challenges in adipose tissue research. …”
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Scrub typhus association with autoimmune biomarkers and clinical implications. by Hwanseung You, Jeongeun Song, Seonglyeong Kim, Sang-Min Oh, Joo-Hee Hwang, Jeong-Hwan Hwang, Wan-Hee Yoo, Yunjung Choi, Chang-Seop Lee

“…These results underline the complex interplay between infectious diseases and autoimmunity, emphasizing the necessity for further research into these mechanisms and their clinical implications.…”
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PHILOSOPHICAL FEATURES OF THE CHINESE MUSICAL TRADITION. GENERAL ANALYSIS by Liu Yongxu

“…The complexity of the ritual required the formation of a mechanism for the harmonization of the sacred-ritual factor through music, songs and dances, which was realized in Chinese culture through the creation of ritual music, which was included as a necessary element in the system of ritual (sacred) and the structure of society (profane) combining them. …”
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Efficient and secure attribute-based heterogeneous online/offline signcryption for body sensor networks based on blockchain by Jawaid Iqbal, Arif Iqbal Umar, Noorul Amin, Abdul Waheed

“…Advancement in wireless technology although improves the patient health–monitoring mechanism, but still there are some limitations regarding security, privacy, and efficiency due to open wireless channel and limited resources of body sensor networks. …”
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