Older Fallers’ Comprehensive Neuromuscular and Kinematic Alterations in Reactive Balance Control: Indicators of Balance Decline or Compensation? A Pilot Study by Ringo Tang-Long Zhu, Timmi Tim Mei Hung, Freddy Man Hin Lam, Jun-Zhe Li, Yu-Yan Luo, Jingting Sun, Shujun Wang, Christina Zong-Hao Ma

“…However, more in-depth neuromuscular/kinematic mechanisms have remained unclear. This study aimed to comprehensively investigate muscle activities and joint kinematics during reactive balance control in older adults with different fall histories. …”
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Determination of the Hydration Damage Instability Period in a Shale Borehole Wall and Its Application to a Fuling Shale Gas Reservoir in China by Haicheng She, Zaiqiang Hu, Zhan Qu, Yao Zhang, Hu Guo

“…During the process of drilling in shale, the complex stress and fluid-structure interactions result in the wall rock generating a strong hydration diffusion and swelling effect, which alters the stress distribution in the rock wall and deteriorates the mechanical parameters of the rock. This results in instability damage of the shale wellbore wall. …”
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THE THEORY OF CIVILIZATIONS THROUGH THE LENS OF CONTEMPORARY HUMANITIES by T. V. Danylova

“…For the preservation and further development of the world civilization, there is no other choice but to elaborate the strategies, mechanisms for consultation and dialogue, cooperation and partnership of civilizations and states. …”
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Does energy-consuming right trading policy achieve a low-carbon transition of the energy structure? A quasi-natural experiment from China by Ye Chen, Bin Zhong, Bingnan Guo

“…IntroductionThe implementation of energy-consuming right trading (ECRT) policy in 2017 is a major measure to promote the construction of ecological civilization and green development, which also aligns with the global trend towards sustainable energy management and carbon emission reduction.MethodsBased on energy consumption data in China from 2010 to 2021, this paper utilizes the Difference-in-Differences (DID) method to assess the extent and process of the impact of energy consuming right trading policy on the low-carbon transition of the energy structure. The transmission mechanism of industrial structure upgrading and the new-quality productive forces in the impact process was discussed, and the regulatory role of environmental regulations was tested.ResultsThe findings indicate: 1) ECRT has a strong driving effect on the low-carbon transition of the energy structure. 2) ECRT can promote low-carbon transition of the energy structure through the dual channel of promoting industrial structure upgrading and new quality productive forces. 3) The influence of ECRT on the low-carbon transition of the energy structure is different in different regions, and the higher degree of industrial agglomeration and renewable energy-rich regions are more significantly promoted by new quality productivity. 4) Environmental regulation has a significant positive moderating effect on the relationship between ECRT and low-carbon transition of the energy structure. 5) Furthermore, the exploratory analysis reveals that the positive impacts of ECRT policies on the low-carbon Transition of the energy structure translates into higher green total factor productivity and lower environmental pollution, which promotes the sustainable development of the low-carbon Transition of the energy structure.DiscussionThis paper responds to the basic question of whether energy use rights policies can promote the low-carbon Transition of the energy structure, and provides empirical evidence and policy reference not only for the development of China’s environmental policy and the direction of energy consumption but also for the international community’s efforts in sustainable energy and environmental governance.…”
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Temporary spinal cord stimulation combined with lidocaine patch for postherpetic neuralgia in the elderly: a controlled study by Yun Li, Chunhui Hao, Shengtao Wang, Feng Qiu, Xuli Zhao, Tao Sun

“…Combining spinal cord stimulation (SCS) with lidocaine patches may enhance pain relief by targeting central and peripheral pain mechanisms.MethodsThis randomized, controlled, single-blind trial enrolled 97 patients aged ≥60 years with PHN lasting ≥6 months. …”
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The heterogeneity of Pinus yunnanensis plantation growth was driven by soil microbial characteristics in different slope aspects by Zhongmu Li, Yong Chai, Chengjie Gao, Jin Li, Kai Cui

“…Abstract The slope aspect is an important environmental factor, which can indirectly change the acceptable solar radiation of forests. However, the mechanism of how this aspect changes the underground ecosystem and thus affects the growth of aboveground trees is not clear. …”
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The Interplay of Aging and PANoptosis in Osteoarthritis Pathogenesis: Implications for Novel Therapeutic Strategies by Liu S, Zhang G, Li N, Wang Z, Lu L

“…Additionally, exploring PANoptosis mechanisms offers potential for innovative OA treatments.Keywords: osteoarthritis, aging, senescence, PANoptosis, inflammation, therapeutic strategies…”
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Protocol for a Phase 2 randomized controlled patient-assessor blinded study: efficacy and safety of combined cortical and cerebellar dual-target transcranial magnetic stimulation f... by Jing Xu, Na Cao, Yan Qu, Suhang Shang, Xincheng Liu, Xuexin Wang, Fangfang Hu, Xuerong Bai, Qiumin Qu, Meng Zhang, Hongmei Cao

“…In this study, we will use left M1 cortex continuous theta-burst stimulation (cTBS) combined with right cerebellar hemisphere 1 Hz repetitive transcranial magnetic stimulation (rTMS) dual-target stimulation to explore the Safety, feasibility and efficiency of this dual-target stimulation mode, and the mechanism of its therapeutic effect.MethodsTwenty-four patients with ET will be randomly assigned to three groups: dual-target stimulation, single-target stimulation, or sham stimulation. …”
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The Application of Incretin-Based Pharmacotherapy in the Contemporary Management of Type 2 Diabetes: A Review of the Literature by Jakub Waszczyński, Wojciech Kulej, Wiktor Biesiada, Piotr Kulej, Justyna Woźniak, Justyna Weronika Kmieć, Anna Mariia Chernysh, Aleksandra Dusińska, Kamila Fuczyło, Karolina Stankević

“…Aim of the Study This study evaluates the mechanisms, efficacy, and benefits of GLP-1 receptor agonists and DPP-4 inhibitors in improving glycemic control, reducing cardiovascular risk, managing weight, and protecting renal function. …”
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Keratinocyte differentiation factor 1 enhances cervical cancer cell viability and migration by activating the PI3K/AKT pathway by Chao Chen, Junhua Liao, Xingxing Sun

“…Background The aim of This study is to investigate the effects of Keratinocyte differentiation factor 1 (KDF1) on cervical cancer cells and the underlying mechanisms.Methods The Gene Expression Profiling Interactive Analysis database was used to analyse KDF1 expression in cervical cancer and paracancerous tissue samples. …”
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Muscle Activations of the Upper Extremity and Core during Elevation and Rotational Movements in Overhead Throwing Athletes by Liam P Owens, Omid Khaiyat, Ginny Coyles

“…Qualitative analysis of muscle patterns during functional tasks reflected a temporal shift in muscle activation timings and magnitudes between athlete groups, suggesting potential compensatory mechanisms in injured athletes. # Conclusion Injured overhead athletes appear to utilize other upper limb and shoulder girdle muscles to compensate for lower upper trapezius activity during functional everyday tasks…”
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Tolerance and accumulation characteristics of Brassica chinensis L. under the interactive treatments of lanthanum, cerium, and fluorine in soil by Ying Jiang, Daixi Zhang, Shirong Zhang, Ting Li, Guiyin Wang, Xiaoxun Xu, Yulin Pu, Lichao Nengzi

“…In this study, the interaction mechanisms of these three pollutants regulating the growth characteristics, antioxidant capacity, and accumulation characteristics of B. chinensis was explored using pot experiments of La-Ce (LC), Ce-F (CF), La-F (LF), and La-Ce-F (LCF) interactions. …”
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ABIN1 Inhibits Inflammation through Necroptosis-Dependent Pathway in Ulcerative Colitis by Jing Bao, Bin Ye, Yuhan Ren

“…Furthermore, we established ABIN1 gain and loss function assay in CACO-2 to confirm the mechanism in UC in vitro. Results. We found that ABIN1, RIPK1, RIPK3, and MLKL were upregulated in UC sample and DSS-induced colitis. …”
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Effect of the Current-Collecting Carbon Nanotubes Layer on the Properties of the Lead Zirconate Titanate Film for Vibration Sensors by Victor V. Petrov, Victor V. Sysoev, Nikolay N. Rudyk, Yuri N. Varzarev, Andrey V. Nesterenko

“…The purpose of this work is to study the effect of a current-collecting layer of CNTs grown over silicon on the properties of a lead zirconate titanate (PZT) film, which is frequently employed in mechanical vibration sensors or energy harvesters. For the experiments, a vibration sensor mock-up was created with the PZT-CNT-Ni-V-SiO₂-Si and PZT-CNT-Ni-V-Si structures where an array of vertically oriented CNTs was grown over an oxidized or high-alloyed silicon substrates by plasma chemical deposition from a gas phase. …”
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Inhaled [D-Ala2]-Dynorphin 1-6 Prevents Hyperacetylation and Release of High Mobility Group Box 1 in a Mouse Model of Acute Lung Injury by Vladislav N. Karkischenko, Veronika I. Skvortsova, Melik T. Gasanov, Yuriy V. Fokin, Maxim S. Nesterov, Nataliya V. Petrova, Oxana V. Alimkina, Igor A. Pomytkin

“…In this study, we demonstrate that inhaled [D-Ala2]-dynorphin 1-6 (leytragin), a peptide agonist of δ-opioid receptors, significantly inhibits HMGB1 secretion in mice with lipopolysaccharide- (LPS-) induced acute lung injury. The mechanism of action involves preventing HMGB1’s hyperacetylation at critical lysine residues within nuclear localization sites, as well as promoting the expression of sirtuin 1 (SIRT1), an enzyme known to deacetylate HMGB1. …”
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In situ template synthesized silver nanoparticulate banana fibre materials with antimicrobial and antibiotic release properties: Efficacy evaluation in ex vivo wound infection mode... by Pompi Das, Debajit Mahanta, Sharmila Giogi, Tarh Kaha, Ngurang Nisha, Sanjeeb Kalita

“…Thermogravimetric analysis (TGA) revealed enhanced thermal stability, with BFS-SNP showing a 25 % improvement in decomposition onset temperature compared to pristine BFS. Mechanical testing demonstrated improved tensile strength in SNP-modified sheets (21.5 ± 0.8 MPa) compared to untreated sheets (16.8 ± 0.7 MPa), highlighting the reinforcement effect of SNP integration. …”
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Sunitinib Reduced the Migration of Ectopic Endometrial Cells via p-VEGFR-PI3K-AKT-YBX1-Snail Signaling Pathway by Xiaodan Fan, Yanyan Tong, Yiting Chen, Yichen Chen

“…Consequently, the purpose of this study is to explore the molecular mechanism by which sunitinib suppressed the ectopic endometrial migration. …”
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Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review by Lou’i Al-Husinat, Shrouq Obeidat, Saif Azzam, Yara Al-Gwairy, Fatima Obeidat, Sarah Al Sharie, Deema Haddad, Fadi Haddad, Martina Rekatsina, Matteo Luigi Giuseppe Leoni, Giustino Varrassi

“…This review examines the use of cannabis in managing chronic non-cancer pain, focusing on its benefits, drawbacks, mechanisms, delivery methods, and impact on quality of life.…”
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Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus by Liwen Zhang, Yu Wan, Liang Ma, Kaihong Xu, Baojin Cheng

“…Bronchiolitis can lead to a significant increase in the incidence of asthma in young children, but the mechanism of bronchiolitis transforming into asthma is still unclear. …”
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Dynamic structural characteristics and vibration susceptibility of Tongren loess under the influence of water content and confining pressure by Changbao Guo, Sanshao Ren, Yinlong Tan, Yaqi Shen

“…This study provides insights into the dynamic structural characteristics of Tongren loess, which can serve as a reference for understanding the formation mechanisms, stability analysis, and seismic design of loess landslides in the region.…”
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