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35481
Presenting a Framework of Effective Factors on the Implementation of Policies in the Field of Protection and Exploitation of Forests in the North of the Country
Published 2024-11-01“…Effective fulfillment of this essential duty requires the establishment of specific, coercive legal mechanisms that clearly delineate the roles and responsibilities of different institutions involved in this area. …”
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35482
Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Inhibit Apoptosis of Pulmonary Microvascular Endothelial Cells in COPD Mice Through miR-30b/Wnt5a Pathway
Published 2025-01-01“…We transfected PMVECs with the miR-30b mimic and Wnt5a overexpression plasmid to assess the underlying mechanisms. Cigarette smoke extract (CSE)-induced COPD mice were treated with exosomes and HBLV-mmu-miR-30b via intratracheal instillation. …”
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35483
Intraoperative evaluation of the intestinal wall viability
Published 2024-12-01“…Special attention is paid to the occlusion-related pathogenetic mechanism of developing mesenteric ischemia, which is accompanied by rapid development of irreversible morphological changes in the tissues and by significant disorders in the homeostasis systems of the organism. …”
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35484
The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase
Published 2020-01-01“…Hypercholesterolemia- (HC-) induced endothelial dysfunction is the first step of atherogenesis, and the peroxisome proliferator-activated receptor γ (PPARγ) has been reported to attenuate atherosclerosis formation; however, the underlying mechanisms are not fully understood. The present study was designed to determine whether myeloperoxidase (MPO) mediates HC-induced endothelial dysfunction and the role of the PPARγ agonist pioglitazone (PIO) in attenuating endothelial dysfunction. …”
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35485
Residual force enhancement decreases when scaling from the single muscle fiber to joint level in humans
Published 2025-12-01“…Conclusion: By comparing rFE across scales within the same participants, we show the development of the rFE non-responder phenomenon is upstream of rFE's cellular mechanisms, with rFE only lost rather than gained when scaling from single fibers to the joint level.…”
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35486
Electrochemically stable and ultrathin polymer-based solid electrolytes for dendrite-free all-solid-state lithium-metal batteries
Published 2025-01-01“…The study offers a new approach for fabricating ultrathin PCSEs and provides insights into the mechanisms of dendrite-free formation, guiding the development of high-performance PCSEs for ASSLMBs.…”
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35487
A novel approach for target deconvolution from phenotype-based screening using knowledge graph
Published 2025-01-01“…Phenotype-based screening can reveal new targets but involves a lengthy process to elucidate mechanisms and targets, hindering drug development. …”
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35488
High-Dose Toremifene as a Promising Candidate Therapy for Hormone Receptor-Positive Metastatic Breast Cancer with Secondary Resistance to Aromatase Inhibitors
Published 2020-01-01“…High-dose TOR appears to be most effective for postmenopausal breast cancer cases with secondary resistance to AIs, cases without prior AI treatment, and cases without liver metastasis. The detailed mechanisms of AI resistance and the clinical features of responsive cases need to be further clarified to identify the best candidates for HD-TOR.…”
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35489
Semantic Segmentation Method for High-Resolution Tomato Seedling Point Clouds Based on Sparse Convolution
Published 2024-12-01“…The feature fusion module based on the attention mechanism is designed by giving the corresponding attention weights to the voxel diffusion features and the point features in order to avoid the ambiguity of points with different semantics having the same characteristics caused by the diffusion module, in addition to suppressing noise. …”
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35490
In Vitro Experimental Assessment of Ethanolic Extract of Moringa oleifera Leaves as an α-Amylase and α-Lipase Inhibitor
Published 2022-01-01“…Moringa oleifera has been scientifically reported to have effects on diabetes and obesity. An explanatory mechanism on how the plant exerts its enzyme inhibitory activities are yet to be detailed. …”
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35491
Comparison of aprepitant versus ondansetron for prevention of postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis
Published 2024-09-01“…Preventing PONV in high-risk patients often requires a multimodal approach combining antiemetic drugs with diverse mechanisms. While aprepitant, a neurokinin-1 receptor antagonist, is recognised as highly effective for PONV prevention, uncertainties remain regarding its effectiveness. …”
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35492
Midostaurin shapes macroclonal and microclonal evolution of FLT3-mutated acute myeloid leukemia
Published 2025-01-01“…Here, we studied the molecular mechanisms underlying refractory/relapsed (R/R) disease in patients with FLT3-mutated AML. …”
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35493
Inhibition of RAC1 activator DOCK2 ameliorates cholestatic liver injury via regulating macrophage polarisation and hepatic stellate cell activation
Published 2025-02-01“…This study aimed to investigate the expression and role of DOCK2 in cholestasis-induced liver fibrosis and to further explore the potential mechanisms. Results Cholestasis was induced in male C57BL/6 mice by bile duct ligation (BDL). …”
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35494
Creating pathways for collaboration between Argentina and the UK to utilise microbial biofilms in sustainable agriculture
Published 2024-02-01“…Despite ongoing research, there are still large knowledge gaps in the understanding of the mechanisms governing interaction between biofilms and plants, and how these can be manipulated to promote sustainable agriculture. …”
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35495
Evaluating the effects of chlorhexidine and vitamin c mouthwash on oral health in non-surgical periodontal therapy: a randomized controlled clinical trial
Published 2025-01-01“…CHX, CHX + VitC, and P mouthwashes appeared to exhibit comparable effects as oral hygiene adjuncts to periodontal mechanical treatment, with the exception of staining, which was more noticeable in the CHX groups compared to the P group. …”
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35496
Crude Oil Foulant Deposition Studies on a Heated Surface Using a Novel Batch Stirred Coupon Test Rig
Published 2022-01-01“…The iron and sulfur content in the hard deposit was more than 45% in total, indicating that the fouling mechanism was corrosion-based resulting from the formation of FeS on the surface. …”
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35497
Lactobacillus acidophilus alleviate Salmonella enterica Serovar Typhimurium-induced murine inflammatory/oxidative responses via the p62-Keap1-Nrf2 signaling pathway and cecal micro...
Published 2025-01-01“…More and more studies have emphasized the broad prospects of probiotics in improving inflammation and oxidative stress, but the ability and mechanism of Lactobacillus acidophilus (LA) to alleviate the inflammatory/oxidative reaction caused by pathogens are still unclear.Methods and resultsIn this study, we treated the mice with LA for 14 days, infected them with S. …”
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35498
Modulation Instability, Analytical, and Numerical Studies for Integrable Time Fractional Nonlinear Model through Two Explicit Methods
Published 2024-01-01“…The present work deals with the investigation of the time-fractional Klein–Gordon (K-G) model, which has great importance in theoretical physics with applications in various fields, including quantum mechanics and field theory. The main motivation of this work is to analyze modulation instability and soliton solution of the time-fractional K-G model. …”
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35499
Left atrial appendage emptying velocity and left ventricular function as predictors of inotropic support in patients undergoing elective off-pump coronary artery bypass grafting
Published 2024-12-01“…These events need to be managed by pharmacological supports or relieving of mechanical obstruction (octopus) of the heart to maintain the hemodynamic stability. …”
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35500
Legal Framework for the Police Commissions: Current State and Prospects for Development
Published 2019-03-01“…It was suggested, therefore, to establish a mechanism, under which the police commissions would draft policing priorities and the respective local councils would adopt them.…”
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