Gap junction intercellular communications regulates activation of SARM1 and protects against axonal degeneration by Wen Jie Zhu, Jun Liu, Wan Hua Li, Zhi Ying Zhao, Chongquan Huang, Jian Yuan Yang, Hon Cheung Lee, Yong Juan Zhao

“…Our results demonstrate a novel intercellular regulation mechanism of SARM1 and reveal a protective role of healthy tissue against AxD induced by injury or neuroinflammation.…”
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Freeze-Thaw Performance of Silt Sand Treated with Lignin by Fu Zhu, Jiayu Li, Wenhao Jiang, Shuang Zhang, Weizhi Dong

“…No new chemical elements, mineral components, or functional groups were produced when lignin was mixed with silt sand. The mechanism by which lignin improved the macroengineering properties of silt sand involved the cementitious material produced by the interaction between lignin and soil minerals, which encapsulated the soil particles and filled the interparticle pores. …”
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H-AMR FORGE’d in FIRE. I. Magnetic State Transitions, Jet Launching, and Radiative Emission in Super-Eddington, Highly Magnetized Quasar Disks Formed from Cosmological Initial Cond... by Nicholas Kaaz, Matthew Liska, Alexander Tchekhovskoy, Philip F. Hopkins, Jonatan Jacquemin-Ide

“…When a = 0.9375 ( a = 0), the energy in mechanical outflows and radiation equals about 60% (10%) and 100% (3%) of the accreted rest mass energy, respectively. …”
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Acute Coronary Syndrome in Acute Myeloid Leukemia with Maturation Accompanying Megakaryocytic Differentiation by Kentaro Odani, Junya Abe, Yoshiaki Tsuyuki, Soshi Yanagita, Kazuya Shiogama, Mitsuhiro Tachibana, Yutaka Tsutsumi

“…AML accompanying megakaryocytic differentiation in certain tissues and organs should be distinguished from acute megakaryoblastic leukemia. The mechanisms provoking acute coronary syndrome in acute myeloid leukemia are discussed.…”
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The box tree moth Cydalima perspectalis: a review of biology, invasiveness, management practices and future perspectives of control strategy in Europe by Marta Budziszewska, Paweł Krystian Bereś

“…This strategy combines biological, chemical, and mechanical methods to reduce populations and limit their destructive impact. …”
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Water utilization strategy of tomato grown on east-west orientation in solar greenhouses revealed based on hydroxide isotopes by Furong Han, Lili Zhangzhong, Wengang Zheng, Jingjing Li, Kaili Shi, Yibo Wei

“…East-west orientation is a strategy that significantly enhances mechanization level within solar greenhouse (SG). However, this orientation alters environmental parameter distribution, affecting soil water use in tomatoes. …”
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The Efficacy of a 6-month Pain Mentoring Program on Pain Knowledge, Beliefs, and Confidence within the United States Department of Veterans Affairs by Wesley Kurszewski, Edward Eichelsdoerfer, Kristin Eneberg-Boldon, Jennifer Gansen, Mark Havran, Molly J. Lahn, Kerry E. Mazzone, Bradley Schaack, Kathryn Schopmeyer, Rebecca Vogsland, Damian Keter

“…Materials and Methods: A 6-month education and mentoring program occurred across three sites with a focus on biopsychosocial pain care principles and treatment based on the mechanism-based classifications of pain. Data collection occurred at baseline, 3 months, and 6 months to include pain knowledge (revised Neurophysiology of Pain Questionnaire [rNPQ]), health-care attitudes and beliefs (Health Care Providers Pain and Impairment Relationship Scale [HC-PAIRS]), self-reported confidence addressing program objectives and self-reported satisfaction in assessing and treating patients with persistent pain. …”
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Glia control experience-dependent plasticity in an olfactory critical period by Hans C Leier, Alexander J Foden, Darren A Jindal, Abigail J Wilkov, Paola Van der Linden Costello, Pamela J Vanderzalm, Jaeda Coutinho-Budd, Masashi Tabuchi, Heather T Broihier

“…Sensory experience during developmental critical periods has lifelong consequences for circuit function and behavior, but the molecular and cellular mechanisms through which experience causes these changes are not well understood. …”
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Effects of hypoxia on the heart of the juvenile four-finger threadfin (Eleutheronema tetradactylum) based on physiological indicators and transcriptome analysis by Yi Lu, Eric Amenyogbe, Ye- Yang, Zhong-liang Wang, Zhong-liang Wang, Zhong-liang Wang, Jing-hui Jin, Rui-tao Xie, Eric Kwabena Droepenu, Jian-sheng Huang, Jian-sheng Huang, Jian-sheng Huang

“…This research provides a foundation for further studies on the molecular mechanisms of hypoxia stress in aquaculture species.…”
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Functional fitness and psychological well-being in older adults by Eliza E. Tóth, Aleksandar Vujić, Ferenc Ihász, Roberto Ruíz-Barquín, Attila Szabo

“…Conclusions These findings should stimulate research on the mechanism connecting functional fitness with PWB in older adults. …”
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How Water Content Can Influence the Chemomechanical Properties and Physical Degradation under Aging of Experimental Adhesives by Stella Renata Machado Silva Esteves, Daphne Camara Barcellos, Tânia Mara da Silva, Mateus Rodrigues Silva, Tiago Moreira Bastos Campos, Elizabeth Pimentel Rosetti, César Rogério Pucci, Sérgio Eduardo de Paiva Gonçalves

“…To evaluate the physicochemical (sorption (SOR), solubility (SOL), and degree of conversion (DC)) and mechanical (flexural strength (FS), modulus of elasticity (ME), and compressive strength (CS)) properties of adhesives with different water contents (D2O). …”
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H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux by Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Jinfeng Zhao, Yajun Zhai, Yajun Zhai, Li Yuan, Li Yuan, Li Yuan, Li Yuan

“…Our findings reveal that H-NS regulates the resistance of E. coli to aminoglycosides by influencing its uptake and efflux, which will enrich our understanding of the mechanism by which H-NS modulates bacterial resistance.…”
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Research on credit card transaction security supervision based on PU learning by Renfeng CHEN, Hongbin ZHU

“…The complex and ever-evolving nature of credit card cash out methods and the emergence of various forms of fake transactions present challenges in obtaining accurate transaction information during customer interactions.In order to develop an accurate supervision method for detecting fake credit card transactions, a PU (positive-unlabeled learning) based security identification model for single credit card transactions was established.It was based on long-term transaction label data from cashed-up accounts in commercial banks’ credit card systems.A Spy mechanism was introduced into sample data annotation by selecting million positive samples of highly reliable cash-out transactions and 1.3 million samples of transactions to be labeled, and using a learner to predict the result distribution and label negative samples of non-cash-out transactions that were difficult to identify, resulting in 1.2 million relatively reliable negative sample labels.Based on these samples, 120 candidate variables were constructed, including credit card customer attributes, quota usage, and transaction preference characteristics.After importance screening of variables, nearly 50 candidate variables were selected.The XGBoost binary classification algorithm was used for model development and prediction.The results show that the proposed model achieve an identification accuracy of 94.20%, with a group stability index (PSI) of 0.10%, indicating that the single credit card transaction security identification model based on PU learning can effectively monitor fake transactions.This study improves the model discrimination performance of machine learning binary classification algorithm in scenarios where high-precision sample label data is difficult to obtain, providing a new method for transaction security monitoring in commercial bank credit card systems.…”
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Hydrogeochemical Characteristics and Formation of Low-Temperature Geothermal Waters in Mangbang-Longling Area of Western Yunnan, China by Xing-Wang Chang, Mo Xu, Liang-Wen Jiang, Xiao Li, Yun-Hui Zhang

“…Numerous low-temperature geothermal waters are distributed extensively in Mangbang-Longling of western Yunnan in China, whose formation mechanism has not been completely investigated yet. …”
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Improving drug repositioning with negative data labeling using large language models by Milan Picard, Mickael Leclercq, Antoine Bodein, Marie Pier Scott-Boyer, Olivier Perin, Arnaud Droit

“…A detailed review of the top 30 revealed 9 promising drugs targeting various mechanisms such as genomic instability, p53 regulation, or TMPRSS2-ERG fusion. …”
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RECEPTION OF THE BIOGRAPHICAL METHOD IN HISTORICAL AND ANTHROPOGICAL STUDIES by T. I. Vlasova, G. G. Krivtchik

“…Among them there is "discovery of the implicit" i.e. not just the description of the results of human cultural activity in the immediate given, but the disclosure of sometimes unconscious mechanisms of this activity, of the deep "springs" of culture that ensure its movement. …”
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Crystallization characteristics of B2O3 and TiO2-bearing glassy fluoride-free mold fluxes by Wang Z., Shu Q.-F., Chou K.-C.

“…The crystallization processes of the studied fluoride-free mold fluxes correspond to the surface crystallization mechanism. This research provides important reference for further investigation on the heat transfer behavior of the TiO2 and B2O3-bearing slag between copper mould and slab to evaluate the feasibility of B2O3 and TiO2- bearing fluoride-free mold fluxes.…”
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Features of therapy selection in patients with glaucoma and “dry eye” syndrome by Zh.G. Oganezova, E.A. Egorov

“…In addition to neuroprotective effect, brimonidine has a double mechanism to reduce the level of IOP: at the same time, it reduces the production of water moisture and activates an uveoscleral outflow. 0.2% solution of brimonidine (Luxfen) contains in its formulation composition a moisturizing component — polyvinyl alcohol, due to which the problem of protecting the eye surface can be solved by prescribing more than one drug containing a preservative for a long period.…”
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A model-based spectral directional approach reveals the long-term impact of COVID-19 on cardiorespiratory control and baroreflex by Beatrice Cairo, Francesca Gelpi, Vlasta Bari, Martina Anguissola, Pavandeep Singh, Beatrice De Maria, Marco Ranucci, Alberto Porta

“…Patients were categorized according to their need of ventilatory support during hospitalization as individuals that had no need of continuous positive airway pressure (noCPAP, n = 27), need of continuous positive airway pressure in sub-intensive care unit (CPAP, n = 14) and need of invasive mechanical ventilation in intensive care unit (IMV, n = 8). …”
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Gut dysbiosis-induced vitamin B6 metabolic disorder contributes to chronic stress-related abnormal behaviors in a cortisol-independent manner by Wenxiang Qing, Huimin Chen, Xin Ma, Jie Chen, Yuan Le, Hui Chen, Jianhua Tong, Kaiming Duan, Daqing Ma, Wen Ouyang, Jianbin Tong

“…These findings show that gut dysbiosis-induced vitamin B6 metabolism disorder is a new non-hypothalamic-pituitary-adrenal axis mechanism of chronic stress-related brain disorders. …”
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