Hubble Space Telescope Observations within the Sphere of Influence of the Powerful Supermassive Black Hole in PKS 0745-191 by Julie Hlavacek-Larrondo, Hyunseop Choi, Minghao Guo, Annabelle Richard-Laferrière, Carter Rhea, Marine Prunier, Helen Russell, Andy Fabian, Jonelle L. Walsh, Marie-Joëlle Gingras, Brian McNamara, Steve Allen, André-Nicolas Chené, Alastair Edge, Marie-Lou Gendron-Marsolais, Michael McDonald, Priyamvada Natarajan, Jeremy Sanders, James F. Steiner, Benjamin Vigneron, Anja von der Linden

“…These results provide valuable insights into the complex mechanisms driving galaxy evolution, highlighting the intricate relationship between SMBH fueling and AGN feedback within the host galaxy.…”
Get full text

Deep learning-based differential gut flora for prediction of Parkinson's. by Bo Yu, Hang Zhang, Min Zhang

“…Finally, a soft voting mechanism was employed to predict Parkinson's disease patients.…”
Get full text

Genomic characterization and molecular predictive biomarkers for chemotherapy in patients with metastatic triple-negative breast cancer treated in a real-world setting by Erik Olsson, Henrik Lindman, Evangelos Digkas, Viktoria Thurfjell, Haidar Mir Ali, Ute Krüger, Anna-Karin Wennstig, Marie Sundqvist, Antonios Valachis

“…Further research into the genomic landscape of tumors from patients with rapid progression or exceptional response to different treatment strategies can provide insights into mechanisms of resistance and identify predictive biomarkers.…”
Get full text

Effects of abscisic acid and gibberellin on sugar accumulation in 'Fengtang' Plum (Prunus salicina LindI.) by Qianjun Song, Xiaoshuang Nie, Hong Chen

“…To investigate the regulation mechanism of exogenous plant growth regulators on the sugar accumulation of 'Fengtang' plum fruits, and to provide theoretical support for improving the sugar content of 'Fengtang' plum fruits. …”
Get full text

Online selfie behavior and consideration of cosmetic surgery in teenage girls: The mediating roles of appearance comparisons and body dissatisfaction. by Yunduan Li, Hong Chen, Yan Zou, Yanshuo Guo, Liying Gao, Xinyu Xu

“…From the perspective of online selfie behaviors, this study explores the relationship between online selfie behaviors and consideration of cosmetic surgery, as well as its internal mechanisms. The study included 762 teenage girls with an average age of 16.85 years who completed the Online Selfie Behavior, Appearance Comparison, Body Dissatisfaction, and Consideration of Cosmetic Surgery scales. …”
Get full text

The interplay between RNA m6A modification and radiation biology of cancerous and non-cancerous tissues: a narrative review by Yajia Cheng, Yue Shang, Shuqin Zhang, Saijun Fan

“…Notably, this review underscores the importance of novel regulatory mechanisms of m6A and their potential clinical applications in identifying epigenetically modulated radiation-associated biomarkers for cancer therapy and estimation of radiation dosages. …”
Get full text

L’image du père et du jardin : Jane Eyre de Charlotte Brontë  et WideSargasso Sea de Jean Rhys by Anne-Marie Baranowski

“…Jane Eyre and Antoinette Cosway are orphaned at an early age, Rochester’s father is depicted as remote and insensitive; the surrogate fathers —Antoinette’s stepfather, Jane’s uncles— mostly fail when they try to replace the missing one. …”
Get full text

Prostate-Specific Membrane Antigen as Target for Neuroimaging of Central Nervous System Tumors by Brittany M. Stopa, James Crowley, Csaba Juhász, Cara M. Rogers, Mark R. Witcher, Jackson W. Kiser

“…Further research is needed regarding the mechanism(s) of PSMA expression in CNS tumors and its differential performance by tumor type.…”
Get full text

Novel coumarin-based acetohydrazide-1,2,3-triazole derivatives as urease enzyme inhibitors: Synthesis, in vitro evaluation, and molecular dynamics simulation studies by Hassan Sepehrmansourie, Mohammad Azimi, Ahmad Ebadi, Gholamabbas Chehardoli, Mohammad Ali Zolfigol, Massoud Amanlou, Mohammad Nazari Montazer, Mohammad Mahdavi, Zahra Najafi

“…Thus, the MD studies confirmed the proposed mechanism of uncompetitive inhibition. Overall, these findings highlight the potential of coumarin-based acetohydrazide-1,2,3-triazole hybrids as potent and novel inhibitors for developing new therapeutics against urease-related diseases.…”
Get full text

Rice glycosyltransferase OsDUGT1 is involved in heat stress tolerance by glycosylating flavonoids and regulating flavonoid metabolism by Guang-rui Dong, Shu-man Zhao, Yi Ding, Yu-qing Ma, Xing-mei Ma, Chong-lin Liu, Bing-kai Hou

“…One significant environmental element influencing the growth and yield of rice (Oryza sativa L.) is high temperature. Nevertheless, the mechanism by which rice responds to high temperature is not fully understood. …”
Get full text

Directions of harmonization of the main principles of domestic administrative and legal science with European integration requirements by O. Yu. Kyrychenko

“…The above-mentioned approaches are aimed at demonstrating to the world community the steady rise of Ukraine as a legal, democratic state, ensuring effective cooperation of state institutions and civil society, guaranteeing commitment to the principles of the rule of law, as well as maintaining the proper level of functioning of the law enforcement mechanism of our country.…”
Get full text

Physiological value of intestinal microflora by S. Yu. Kuchumova, Ye. A. Poluektova, A. A. Sheptulin, V. T. Ivashkin

“…Further studying of its functions, the states interfering qualitative and quantitative composition of microorganisms, colonizing human gastrointestinal tract, as well as the mechanism of action of probiotics and drugs of symptomatic action (defoamers) is necessary.…”
Get full text

Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

“…HIV infection augments angiogenesis via several mechanisms, most prominently, by the trans-activator of transcription (tat) protein mimicking VEGF-A by binding to its receptor, VEGFR-2, as well as upregulation of NRP-1, which enhances the interaction between VEGF-A and VEGFR-2. …”
Get full text

Multiple Organ Failure Associated with SARS-CoV-2 Infection in a Child with Down Syndrome: Is Trisomy 21 Associated with an Unfavourable Clinical Course? by Perla Idalia Vazquez-Hernández, Alan Cárdenas-Conejo, Manuel Alejandro Catalán-Ruiz, Karla Navar-Gallegos, Emilio Zenteno-Salazar, Jose Rafael-Parra-Bravo, Ranferi Aragon-Nogales, Maribel Ibarra-Sarlat, Juan Carlos Núñez-Enríquez

“…Female, 2 years old, karyotype 47,XX,+21[30], previously diagnosed with a cyanotic congenital heart disease (tricuspid atresia and infundibular pulmonary stenosis, type Ib) who started with diarrhea, developed shortness of breath, and cyanosis and was admitted to the hospital presenting low-oxygen saturation (33%) requiring invasive mechanical ventilation support. The patient tested positive for SARS-CoV-2 infection. …”
Get full text

Vegetation restoration effectiveness with main factors in the Beijing-Tianjin sandstorm source region during 2000-2020, China. by Xingshuo Zhang, Jingfang Yuan, Xiaoman Liu, Cheng Zong

“…Here, we employed the comprehensive vegetation parameters to describe the vegetation restoration effectiveness, and examined the driving mechanism of natural and human factors in different sub regions. …”
Get full text

Effect of Ni/Sn ratio on microstructure and properties of Cu-Ni-Sn-P alloy by Xiaokang Chen, Xiangpeng Xiao, Dawei Yuan, Jinshui Chen, Yu Wu

“…The precipitates in the Cu-Ni-Sn-P alloy with Ni/Sn = 2/1 were rod-shaped. The strengthening mechanisms of the three alloys were Orowan strengthening, grain boundary strengthening, solid solution strengthening and dislocation strengthening, and Orowan strengthening was dominant. …”
Get full text

Stability Analysis of Ecological Slopes Based on a 3D Finite Element Model by ZiFan Sui, Weijia Yuan, Wen Yi, Weihuan Yang

“…The plant distribution characteristics and mechanical properties are analyzed. This paper uses ABAQUS finite element software to construct a 3D model of the planted slope in the test section. …”
Get full text

TOWARDS GENDER EQUALITY: UKRAINE IN THE 21ST CENTURY by Tetyana V. Danylova

“…Conclusion. Appropriate mechanisms for overcoming gender stereotypes will contribute to integration of equal rights’ principle and opportunities.  …”
Get full text

Fade into you: genetic control of pigmentation patterns in red-flesh apple (Malus domestica) by Pierre Bouillon, Pierre Bouillon, Etienne Belin, Anne-Laure Fanciullino, Sandrine Balzergue, Sandrine Balzergue, Sylvain Hanteville, Yao Letekoma, Maryline Cournol, Fatima Faris, Andréa Bouanich, Dimitri Bréard, Frédéric Bernard, Jean-Marc Celton

“…To further investigate the mechanisms involved in the spatial deposition of anthocyanin, metabolome, transcriptome and methylome comparisons between white and red flesh areas within the red-flesh genotype cv. …”
Get full text

Immediate Effect of Kinetic Chain Activation and Mulligan’s Bent Leg Raise Technique in Patients with Asymptomatic Hamstring Tightness: A Randomised Clinical Trial by Santosh Channabasapa Metgud, Santosh D Patil, Omkar Anand Gaonkar

“…Introduction: Hamstring shortness is an important mechanical marker for hamstring strain injuries, often related to a muscle imbalance between the quadriceps and hamstrings. …”
Get full text