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35121
Hypericin-Mediated Photodynamic Therapy for Head and Neck Cancers: A Systematic Review
Published 2025-01-01“…<b>Objectives</b>: We aimed to evaluate the efficacy and underlying mechanisms of hypericin-mediated PDT (HY-PDT) in treating head and neck cancers. …”
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35122
Correlation among blastocoel fluid DNA level, apoptotic genes expression and preimplantation aneuploidy
Published 2025-02-01“…It is believed that aneuploid embryos release cell-free DNA (cfDNA) into the blastocyst cavity during the self-correction process through the apoptotic mechanism. This study aimed to develop less invasive methods for predicting ploidy status by investigating how ploidy status affects blastocoel fluid DNA (BF-DNA) levels and apoptotic gene expression as indicators of embryo viability. …”
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35123
Effect of prolonged starvation on nutrition utilization and transcriptional responses in Pacific oyster (Crassostrea gigas)
Published 2025-03-01“…Emaciation syndrome due to starvation is a significant cause of mortality in marine animals, yet the underlying mechanisms in non-feeding and weak/no-mobility marine bivalves remain poorly understood. …”
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35124
Explainable correlation-based anomaly detection for Industrial Control Systems
Published 2025-02-01“…This is achieved through an anomaly detection module that incorporates a threshold mechanism, utilizing alpha and epsilon values. The proposed method utilizes a novel set of input features extracted using the Shapley Additive explanation (SHAP) framework to train and evaluate the MGD model. …”
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35125
Expression study of Wnt/β-catenin signaling pathway associated lncRNAs in schizophrenia
Published 2025-01-01“…Abstract Schizophrenia is one of the most debilitating mental illnesses affecting any age group. The mechanism and etiology of schizophrenia are extremely complex and multiple signaling pathways recruit genes implicated in the etiology of this disease. …”
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35126
Multiscale Method for Seismic Response of Near-Source Sites
Published 2020-01-01“…The generalized free-field seismic response of the near-source region is obtained by establishing a large-scale calculation model of the source site and is used to simulate the fracture mechanism of faults and the process of seismic wave propagation. …”
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35127
Design and Optimization of a Lightweight and Simple Self-Propelled Crawler Potato Combine Harvester
Published 2024-12-01“…To address the inadequacies of mechanized potato-harvesting equipment on challenging terrains like hills, mountains, and small fields, a lightweight and simple self-propelled crawler potato combine harvester was developed based on the agronomic and harvesting requirements of potato cultivation. …”
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35128
Ewing sarcoma – pathomechanisms, standard treatment and new therapeutic perspectives
Published 2025-01-01“…Conclusions: They are new and promising approaches in cases where standard treatments fail, yet they still require further study. Knowledge of the mechanisms of Ewing's sarcoma formation and its metastases, currently accepted treatment standards, critical points in the pathomechanism and current attempts at treating Ewing's sarcoma is essential for choosing the best treatment and effectively reducing its mortality rate. …”
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35129
Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cel...
Published 2021-01-01“…However, the molecular mechanisms driving breast cancer initiation or enhancement by inflammation are yet to be deciphered. …”
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35130
The European Court of Human Rights as Part of Criminal Procedural Legislation of Ukraine
Published 2020-09-01“…Since the Convention for the Protection of Human Rights and Fundamental Freedoms has become part of national legislation after its ratification by the Verkhovna Rada of Ukraine, more detailed study should be conducted regarding the urgent task of fully understanding the content of this international treaty and the main mechanisms for implementing its norms. The author has analyzed the implementation of the case law of the European Court of Human Rights on the example of its specific decisions into criminal procedural legislation of Ukraine by applying the decisions of the European Court of Human Rights by the Grand Chamber of the Supreme Court in its activities and problematic aspects of their practical implementation. …”
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35131
AaMYB61-like and AabHLH137 jointly regulate anthocyanin biosynthesis in Actinidia arguta
Published 2025-01-01“…Conclusions Our study not only reveals the functions of AaMYB61-like and AabHLH137 in anthocyanin regulation, but also broadly enriches color regulation theory, establishing a foundation for clarifying the molecular mechanism of fruit coloration in kiwifruit.…”
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35132
Construire un outil d’association de données à l’heure de l’open data : La Fabrique Numérique du Passé (FNP)
Published 2023-11-01“…Like Gaignières in his day, current trends and public policies to open up data are re-examining the mechanisms for collecting, making available and exploiting bodies of information that are now digital. …”
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35133
The European Union’s Assistance to Morocco (1999–2011): Strategic Directions, Priority Areas, and Main Outcomes
Published 2020-11-01“…The author examines aid delivery mechanisms, distribution of aid through the Government and to civil society institutions in Morocco, as well as terms of such assistance. …”
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35134
In vitro and in vivo anti-hyperglycemia effects of extract of Faloak (Sterculia quadrifida R.Br.) leaves
Published 2024-11-01“…Identifying active ingredients paves the way for further research to elucidate specific bioactive compounds and their mechanisms of action …”
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35135
Dynamic Detection of Monocyte Subsets in Peripheral Blood of Patients with Acute Hypertriglyceridemic Pancreatitis
Published 2019-01-01“…Hypertriglyceridemic pancreatitis (HTGP) is always more severe than normal lipid-AP, whether the mechanism of aggravation involves monocyte subsets remains unknown though. …”
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35136
Sesame Oil (Sesamum Indicum L.) as a New Challenge for Reinforcement of Conventional Glass Ionomer Cement, Could It Be?
Published 2021-01-01“…Despite the advantages of glass ionomer cement (GIC) including chemical bonding to the tooth structure and fluoride release, its low-grade mechanical properties make it a topic for research. …”
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35137
Structural bioinformatic study of six human olfactory receptors and their AlphaFold3 predicted water-soluble QTY variants and OR1A2 with an odorant octanoate and TAAR9 with spermid...
Published 2025-01-01“…The molecular mechanism of olfaction, namely, how we smell with limited olfactory receptors to recognize exceedingly diverse and large numbers of scents remains unknown despite the recent advances in chemistry, chemical, structural, and molecular biology. …”
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35138
Defence counsel's participation in a special pre-trial investigation of criminal offenses
Published 2021-12-01“…These include inconsistent provisions of the law on the initial moment of involvement of a defence counsel in a special pre-trial investigation, imperfection of the procedural mechanism for engaging a defense counsel, whose participation is mandatory when considering a request of an investigator or prosecutor for a special pre-trial investigation. to the regional centers of secondary legal aid, assessment of the services quality and proper performance by a lawyer who provides free of charge to the suspect (accused), his or her responsibilities, the possibility of replacing a lawyer, and another problems. …”
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35139
2-Brain Regulation for Improved Neuroprotection during Early Development (2-BRAINED): a translational hyperscanning research project
Published 2025-01-01“…Electroencephalography (EEG) hyperscanning allows the assessment of brain-to-brain co-regulation during live interaction between infants and parents, offering promising insights into the mechanisms behind the interactive benefits of early VF interventions.GoalsThis study aimed to compare indices of brain-to-brain co-regulation between dyads of full-term (FT) and VPT infants interacting with their mothers and investigate the effect of an early post-discharge VF intervention on the brain-to-brain co-regulation indices of VPT dyads.Methods and analysisVPT and FT dyads will be enrolled at birth, and the former will be randomly allocated to one of two arms: VF intervention or care as usual. …”
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35140
A Predicted Helix-Turn-Helix Core Is Critical for Bacteriophage Kil Peptide to Disrupt <i>Escherichia coli</i> Cell Division
Published 2025-01-01“…<b>Methods</b>: To investigate Kil’s molecular mechanism further, we employed deletions, truncations, and molecular modeling to identify the minimal residues necessary for its activity. …”
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