Effects of the Coronavirus Disease 2019 (COVID-19) Pandemic on Outcomes among Patients with Polytrauma at a Single Regional Trauma Center in South Korea by Sun Hyun Kim, Dongyeon Ryu, Hohyun Kim, Kangho Lee, Chang Ho Jeon, Hyuk Jin Choi, Jae Hoon Jang, Jae Hun Kim, Seok Ran Yeom

“…There was no difference in mechanisms of injury between the two periods. For patients admitted during the COVID-19 period, the hospital LOS was significantly shorter (10 days [interquartile range (IQR) 4–19 days] vs. 16 days [IQR 8–28 days], p<0.001); however, no significant differences in ICU LOS and mortality were found. …”
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Single‐cell dissection reveals immunosuppressive F13A1+ macrophage as a hallmark for multiple primary lung cancers by Chenglin Yang, Jiahao Qu, Jingting Wu, Songhua Cai, Wenyi Liu, Youjun Deng, Yiran Meng, Liuqing Zheng, Lishen Zhang, Li Wang, Xiaotong Guo

“…However, the molecular mechanisms driving MPLCdevelopment and distinguishing it from solitary primary lung cancers (SPLCs)remain largely unexplored. …”
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Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway by Qiaoli Chen MS, Quanxiang Hao MBBS, Yanping Yang MBBS, Limei Li PhD, Danping Li MS, Ran Zhao MS, Wanqi Wei MBBS, Lixian Deng MBBS, Jiaming Su MBBS, Ziyuan Liang MBBS, Shiyue Tang MS, Yaomin Lu MBBS, Yushan Liang PhD, Zhe Zhang PhD, Xiaoying Zhou PhD, Xue Xiao PhD, Ping Li PhD, Yi Huang PhD, Weilin Zhao PhD

“…Here, we aim to investigate the expression, cellular biological functions, and the potential underlying mechanism of CES4A in nasopharyngeal carcinoma (NPC). …”
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The influence of childhood trauma on social media-induced secondary traumatic stress among college students: the chain mediating effect of self-compassion and resilience by Xiqin Liu, Ye Yao, Siyu Zhu, Qiyong Gong

“…However, whether these variables are associated with social media-induced STS in college students and the underlying mechanisms remain unclear. The purpose of this study was to explore the complex relationship linking childhood trauma to social media-induced STS in a large sample of college students.Methods: A total of 1151 Chinese college students from Chengdu, Sichuan Province of China completed a web-based cross-sectional survey, which included standard assessments of childhood trauma, self-compassion, resilience and social media-induced STS, as well as sociodemographic questionnaires. …”
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Dynamic simulation of landscape ecological risk in Gansu’s farming-pastoral ecotone based on topographic gradients by Le Yang, Jixuan Yan, Guang Li, Weiwei Ma, Tao Li, Pengcheng Gao, Qiang Li, Xiangdong Yao, Jie Li, Wenning Wang

“…Consequently, land-use planning should be tailored to local conditions, and a long-term monitoring mechanism should be established. This study provides novel insights into the spatiotemporal changes in landscape ecological risk in ecologically vulnerable areas, focusing on topographic gradients.…”
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Case Report: Concurrent primary CNS lymphoma and meningothelial meningioma - nuances of diagnosis and management [version 2; peer review: 1 approved, 2 approved with reservations] by Rosalinda Menoni, Ira Bowen, Dan Miulli, Jacob Bernstein, Samir Kashyap

“…Case Description: A 64-year-old female with history of diabetes mellitus type 2 initially presented to the Emergency Department, two weeks prior, following a mechanical fall at home resulting in a left bimalleolar fracture. …”
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A realist evaluation to explain and understand the role of paramedics in primary care by Georgette Eaton, Geoff Wong, Stephanie Tierney, Veronika Williams, Kamal R. Mahtani

“…Results The culmination of findings from each phase led to the development of a final programme theory, comprising of 50 context-mechanism-outcome configurations (CMOCs) encompassing three conceptual categories: Expectations associated with paramedics in primary care, the transition of paramedics into primary care roles, and the roles and responsibilities of paramedics in primary care. …”
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Negligible contribution of body density to in-water vertical jump performance in elite male water polo players. by Bence Balázs, Balázs Sebesi, Alexandra Cselkó, Márk Váczi

“…Seventeen elite water polo players from Hungarian first league were tested for dry-land counter movement and squat jump mechanical impulse, isometric squat force, and in-water vertical jump height. …”
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Conflict Probability Prediction and Safety Assessment of Straight-Left Traffic Flow at Signalized Intersections by Yingying Ma, Zihao Zhang, Jiabin Wu

“…A case study was conducted to reveal the evolution mechanism of the conflict risk coefficient at the signalized intersection and to estimate the safety status under the various security optimization strategies. …”
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Application of a Multi‐Layer Artificial Neural Network in a 3‐D Global Electron Density Model Using the Long‐Term Observations of COSMIC, Fengyun‐3C, and Digisonde by Wang Li, Dongsheng Zhao, Changyong He, Yi Shen, Andong Hu, Kefei Zhang

“…The new model is expected to play an important role in the application of GNSS navigation and in the explanation of the physical mechanisms involved.…”
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Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway by Jianming Tang, Yu Cao, Hong Zhang, Rui Wang

“…Therefore, the demand remains to explore potential novel and effective mechanism underlying radioresistance to improve the efficacy of radiotherapy for NSCLC. …”
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Transcriptome analysis reveals the genetic basis underlying the formation and seasonal changes of nuptial pads in Rana chensinensis by Fuyuan Qiu, Qingbo Ai, Jun Li, Hua Wu

“…However, the genetic mechanisms underlying its formation and seasonal changes remain poorly understood. …”
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Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice by Tianchan Peng, Jian Xiang, Yun Tian, Xiaogen Tang, Lina Wang, Lijuan Gao, Oscar Junhong Luo, Li’an Huang, Guobing Chen

“…Objective: To investigate the geroprotective effects of Lycium barbarum glycopeptide (LbGp) and its potential mechanisms in a D-galactose-induced accelerated aging mouse model. …”
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Antibacterial, Antibiofilm, and Efflux Pump Inhibitory Properties of the Crude Extract and Fractions from Acacia macrostachya Stem Bark by Akua Frema Barfour, Abraham Yeboah Mensah, Evelyn Asante-Kwatia, Cynthia Amaning Danquah, Daniel Anokwah, Silas Adjei, Michael Kwesi Baah, Merlin L. K. Mensah

“…This study justifies the use of A. macrostachya in the treatment of infections in traditional medicine and highlights its potential as a source of bioactive compounds that could possibly interact with some resistance mechanisms in bacteria to combat antimicrobial resistance.…”
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Myeloid cell-derived apCAFs promote HNSCC progression by regulating proportion of CD4+ and CD8+ T cells by Feilong Ren, Lin Meng, Shize Zheng, Jiasen Cui, Shaoyi Song, Xing Li, Dandan Wang, Xing Li, Qilin Liu, Wenhuan Bu, Hongchen Sun

“…Our current study tried to explore the origin, mechanism, and function of the apCAFs in the HNSCC. …”
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Chemokine associations with blood cerebrospinal fluid (CSF) barrier permeability and delirium by Paul Denver, Lucas Tortorelli, Karen Hov, Jens Petter Berg, Lasse M. Giil, Arshed Nazmi, Ana Lopez-Rodriguez, Daire Healy, Carol Murray, Robyn Barry, Leiv Otto Watne, Colm Cunningham

“…Delirium is a highly prevalent neuropsychiatric syndrome characterised by acute and fluctuating impairments in attention and cognition. Mechanisms driving delirium are poorly understood but it has been suggested that blood cytokines and chemokines cross the blood brain barrier during delirium, directly impairing brain function. …”
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Bending Properties of Short-Cut Basalt Fiber Shotcrete in Deep Soft Rock Roadway by Shaoyang Yan, Huazhe Jiao, Xiaolin Yang, Jinxing Wang, Fengbin Chen

“…A transparent soil model and Scanning Electron Microscopy (SEM) were used to observe the distribution of BF with different volume fractions and analyze the toughness enhancement mechanism of basalt fiber shotcrete. The supporting effect of basalt fiber shotcrete with different volume fractions was verified by an underground engineering test. …”
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Long-Pulse Gastric Electrical Stimulation Repairs Interstitial Cells of Cajal and Smooth Muscle Cells in the Gastric Antrum of Diabetic Rats by Yan Chen, Hongcai Wang, Hai Li, Shi Liu

“…Gastric electrical stimulation (GES) is an efficient therapy for gastric motility disorders, but the mechanisms of GES require clarification. Methods. Male rats were randomly divided into the control group, diabetic rat group (DM), diabetic rats with sham GES group (DM + SGES), and diabetic rats with different frequency GES group (DM + GES) (GES1: 5.5 cpm, 100 ms, 4 mA; GES2: 5.5 cpm, 300 ms, 4 mA; and GES3: 5.5 cpm, 550 ms, 2 mA). …”
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Sequence of episodic memory-related behavioral and brain-imaging abnormalities in type 2 diabetes by Bo Hu, Ying Yu, Xin-Wen Yu, Min-Hua Ni, Yan-Yan Cui, Xin-Yu Cao, Ai-Li Yang, Yu-Xin Jin, Sheng-Ru Liang, Si-Ning Li, Pan Dai, Ke Wu, Lin-Feng Yan, Bin Gao, Guang-Bin Cui

“…To comprehensively explore the neural mechanisms underlying it, we aimed to explore the sequence that episodic memory-related behavioral and brain-imaging biomarkers appear abnormal in the progression of T2D. …”
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Integration of wireless power transfer and low power wide area networks in IoT applications—A review by Molefi J. Makhetha, Elisha D. Markus, Adnan M. Abu-Mahfouz

“…Conversely, due to these devices’ locations (hard-to-reach/hazardous), it is a challenge to sustainably charge them and for the power sources or their mechanisms to last for longer term. This review analyses recent work on LPWANs and low power WPT with strong focus on the main challenges and key solutions that would allow for their integration in IoT applications. …”
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