LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17 by Chanjiao Yao, Lingjuan Zeng, Qin Liu, Xiaoxin Qiu, Chunyan Chen

“…This study aimed to explore the roles and mechanisms of lncRNA FAM225B and PDIA4 in ovarian cancer. …”
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Influence of Fiber Orientation on Impact Resistance Behavior of Woven Sisal Fiber Reinforced Polyester Composite by Genetu A. Dress, M. H. Woldemariam, D. T. Redda

“…Woven natural fiber reinforced polymer composites have better tensile, flexural, and compressive strength compared to the mechanical properties of unidirectional and randomly oriented NFRPC because of the interlacing of fiber bundles. …”
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Soil fertility differences due to tillage methods modulate maize yield formation at different planting densities by Li-Qing Wang, Da-Ling Ma, Hong-yue Liu, Shu-Ping Hu, Xiao-Fang Yu, Ju-Lin Gao

“…This study aims to elucidate the regulatory mechanism by which soil fertility augmentation affects maize yield formation under a variety of planting densities. …”
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mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction by Seon-Yeong Lee, Jeonghyeon Moon, A Ram Lee, Young-Mee Moon, Jeong Won Choi, Chae Rim Lee, Su Been Jeon, Hee Su Sohn, Jeehee Youn, Dongyun Shin, Sung-Hwan Park, Mi-La Cho

“…Therefore, this study suggests a novel inhibitory mechanism of RA using mitoSTAT3 via the regulation of autophagy, Th17 differentiation, and inflammatory cell death.…”
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Prioritization of causal genes from genome-wide association studies by Bayesian data integration across loci. by Zeinab Mousavi, Marios Arvanitis, ThuyVy Duong, Jennifer A Brody, Alexis Battle, Nona Sotoodehnia, Ali Shojaie, Dan E Arking, Joel S Bader

“…Better prioritization and prediction of causal genes could reveal disease mechanisms and suggest interventions.<h4>Results</h4>We describe a new Bayesian method, termed SigNet for significance networks, that combines information both within and across loci to identify the most likely causal gene at each locus. …”
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Analysis of the Coupling Coordination and Spatiotemporal Evolution of High-Tech Industrial Technological Innovation and Regional Economic Development by Xu-Mei Yuan, Fu-Li Wei, Hui Li, Ying An

“…Based on the analysis of the mechanism of high-tech industrial technological innovation and regional economic development, this paper constructs the measurement index system of high-tech industrial technological innovation and regional economic development, and the chain network DEA model, entropy weight method, coupling coordination model, and exploratory spatial data analysis technology are comprehensively used to empirically analyze the technological innovation efficiency of high-tech industries, regional economic development level, and the coupling coordination relationship between them and the spatiotemporal evolution trend in 24 provinces (cities) of China from 2009 to 2018. …”
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Impact of obesity on iron metabolism and the effect of intravenous iron supplementation in obese patients with absolute iron deficiency by Laura Tarancon-Diez, Marianela Iriarte-Gahete, Pilar Sanchez-Mingo, Mª Ángeles Muñoz-Fernandez, Maria Luisa Navarro-Gomez, Yolanda M. Pacheco, Manuel Leal

“…Abstract Obesity and iron deficiency (ID) are widespread health issues, with subclinical inflammation in obesity potentially contributing to ID through unclear mechanisms. The aim of the present work was to elucidate how obesity-associated inflammation disturb iron metabolism and to investigate the effect of intravenous (IV) iron supplementation on absolute iron deficient pre-obese (BMI 25.0–29.9 kg/m2) and obese (BMI > 30 kg/m2) individuals compared to healthy weight (HW) group (BMI 18.5–24.9 kg/m2). …”
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Evolutionary analysis of DELLA proteins in sweet potato and related species reveals their roles in development and stress responses by Zhidan Zuo, Haoqiang Zhao, Yue Fan, Yixuan Zhu, Wenpeng Song, Hong Zhai, Shaozhen He, Huan Zhang, Ning Zhao, Qingchang Liu, Shaopei Gao

“…The cis-regulatory elements of the DELLA gene in selected Ipomoea species contain unique promoter elements, indicating the presence of species-specific regulatory mechanisms. A multitude of shared cis-regulatory elements related to stress responses were identified in the DELLA gene promoters. …”
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Non-governmental organizations’ perceptions of challenges and opportunities for participating in the provision of government-purchased community-based psychiatric rehabilitation se... by Hao Yao, Siyuan He, Fei Yan, Wei Wang, Hanyi Lin, Yanli Liu, Lili Xue, Jun Cai, Weibo Zhang

“…Conclusions Based on the findings, recommendations for future actions are provided in the areas of research, public awareness, funding, training, referrals, collaboration, and service designing to improve the mechanism of government purchasing of CBPR services from NGOs in China.…”
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Se-methylselenocysteine inhibits inflammatory response in an LPS-stimulated chicken HD11 macrophage-like cell model through the NFKB2 pathway by Min Yao, Binyu Wang, Zitong Li, Suqing Wu, Bingyu Zhao, Ning Sun, Huiping Xiao, Jianwu Wang, Guoping Liu, Tinghua Huang

“…This study identified key transcription factors and revealed one of the potential mechanisms through which SeMC exerts its anti-inflammatory effects from the perspective of transcriptional regulation.…”
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Study of the Windowing and Overlap-Add Operation for a Super-Gaussian Random Vibration Test by Yiming Peng, Yang Li

“…Based on the analysis, a further study is made to explain the mechanism of the kurtosis decrease due to the WOA method. …”
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Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis [version 2; peer review: 1 approve... by Spyridon Siafis, Johannes Schneider-Thoma, Alexandra Bannach-Brown, Oliver D. Howes, Virginia Chiocchia, Ulf Tölch, Natascha I. Drude, Sabine M. Hölter, Andrea de Bartolomeis, Anthony C. Vernon, Georgia Salanti, Sridhar Natesan, Stefan Leucht, Irene Bighelli, Sameer Jauhar, Ioannis Mantas, Josef Priller, Francesca Tinsdeall, Wulf-Peter Hansen, Fiona J. Ramage, Nobuyuki Nomura, Malcolm R. Macleod

“…Background Muscarinic receptor agonism and positive allosteric modulation is a promising mechanism of action for treating psychosis, not present in most D2R-blocking antipsychotics. …”
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Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target by Chao Xu, Litao Liang, Guoqing Liu, Yanzhi Feng, Bin Xu, Deming Zhu, Wenbo Jia, Jinyi Wang, Wenhu Zhao, Xiangyu Ling, Yongping Zhou, Wenzhou Ding, Lianbao Kong

“…Conclusion ACRRGs, particularly MORF4L1, play crucial roles in modulating HCC progression, offering new insights into the molecular mechanisms driving HCC and potential therapeutic targets. …”
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DMRIntTk: Integrating different DMR sets based on density peak clustering. by Wenjin Zhang, Wenlong Jie, Wanxin Cui, Guihua Duan, You Zou, Xiaoqing Peng

“…In addition, the overlap analysis suggests that the integrated DMR sets are quite comprehensive, and functional analyses indicate the integrated disease-related DMRs are significantly enriched in biological pathways associated with the pathological mechanisms of the diseases. A comparative analysis of the integrated DMR set versus each original DMR set further highlights the superiority of DMRIntTk, demonstrating the unique biological insights it can provide.…”
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Variability of morphometrical characteristics of needles at a clonal plantation of plus trees of scots pine (Pinus sylvestris L.) by N. N. Besschetnova, V. P. Besschetnov

“…This problem is related to the risk of inbreeding depression of the seed progeny of plus trees, which do not have any defense mechanism against self-pollination. Economically, the Scots pine is one of the most important wood species. …”
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Clinical Presentations and Characteristics of NSAIDs Hypersensitivity in a Tertiary Care Hospital in Indonesia: A Case Series by Nurmesa A, Zakiyah N, Insani WN

“…This case series provides valuable insights into the clinical presentations and potential mechanisms of NSAID hypersensitivity in the documented cases in one of the hospitals in Indonesia. …”
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Electro-Oxidation of Glycerol on Core–Shell M@Pt/C (M = Co, Ni, Sn) Catalysts in Alkaline Medium by Rudyere Nascimento Silva, Leandro Aparecido Pocrifka, Ermete Antolini, Raimundo Ribeiro Passos

“…Furthermore, Sn@Pt/C displayed remarkable poisoning tolerance attributed to a combined effect: a bifunctional mechanism driven by Sn oxides and an electronic effect within the PtSn alloy. …”
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15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity by Kan Chen, Jingjing Li, Junshan Wang, Yujing Xia, Weiqi Dai, Fan Wang, Miao Shen, Ping Cheng, Yan Zhang, Chengfen Wang, Jing Yang, Rong Zhu, Huawei Zhang, Yuanyuan Zheng, Jie Lu, Zhuoyi Fan, Yingqun Zhou, Chuanyong Guo

“…In this study, we investigated both effects of 15d-PGJ2 and its protection mechanism in concanavalin A- (ConA-) induced autoimmune hepatitis in mice. …”
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Analysis of Iranian health workforce emigration based on a system dynamics approach: a study protocol by Hamideh Keyvani, Reza Majdzadeh, Esmaeil Khedmati Morasae, Leila Doshmangir

“…The primary objective is to gain a profound understanding of the underlying causes, mechanisms, and consequences of migration, as well as assess the impact of policies, in order to prioritize effective interventions. …”
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Spatio-temporal dynamics of grassland ecosystem services and the segmentation effects of their drivers: A case in South China Karst by Yongyao Li, Kangning Xiong, Wenfang Zhang, Shuai Xiang, Baoshan Zhang, Rong Li

“…Our research results open a new perspective for the study of the impact mechanism of grassland ES. It can enrich the understanding of grassland ES and offer valuable insights to guide future initiatives for ecosystem restoration and sustainable development in ecologically fragile, particularly karst, areas.…”
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