Impact of Long-Term Cold Storage on the Physicochemical Properties, Volatile Composition, and Sensory Attributes of Dried Jujube (<i>Zizyphus jujuba</i> Mill.) by Shaoxiang Pan, Xuemei Liu, Xiaodong Zheng, Jihong Wu, Mengnan Tan, Ning Cao, Xinyu Zhao, Maoyu Wu, Yu Han, Xinhuan Yan, Ye Song

“…Future research should focus on elucidating the underlying mechanisms of these changes, identifying key markers for quality control during grey jujube storage, and providing a scientific basis for distinguishing between newly harvested and aged grey jujubes, while improving storage quality.…”
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Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research by Foteini Stefania Koumpa, Diamantis Xylas, Maciej Konopka, Dieter Galea, Kirill Veselkov, Anthony Antoniou, Akash Mehta, Reza Mirnezami

“…Early diagnosis and a deeper understanding of the biological mechanisms that regulate CPM are critical to refining patient selection for radical treatment, personalising therapeutic approaches, enhancing prognostication, and ultimately improving long-term survivorship. …”
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THE STRATEGY FOR CREATION OF THE MODERN CONCEPT OF INTEGRATIVE-HOLISTIC EDUCATION (A CASE STUDY OF MINING SCHOOLS OF THE URALS) by N. K. Chapaev, M. A. Choshanov

“…The relevance of the problem under study is caused by the contradiction between the necessity of fundamentalization of education, raising it to the level of the requirements of integral human development and the deepening disintegration of all sides of his life, including vocational education.The aim of the present publication is philosophical and pedagogical reflection and development of mechanisms for mainstreaming integrative-holistic approach when building a hypothetical model of professional education, aimed at provision of strategic turn towards more balanced (dialectical) approach to the traditional values of education. …”
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Earthquake Disaster Rescue Model Based on Complex Adaptive System Theory by Fujiang Chen, Jingang Liu, Junying Chen

“…In this paper, through the task allocation mechanism task, the disaster rescue task is divided into simple task and complex task, and the executive task subject is divided into single task subject and multitask subject. …”
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Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit by Fei Wu, Yuanyuan Ying, Min Yin, Yi Jiang, Chongyang Wu, Changrui Qian, Qianqian Chen, Kai Shen, Cong Cheng, Licheng Zhu, Kewei Li, Teng Xu, Qiyu Bao, Junwan Lu

“…To investigate the mechanisms of multiple resistance and the horizontal transfer of resistance genes in animal pathogens, we characterized the molecular structures of the resistance gene-related sequences in a multidrug-resistant Klebsiella pneumoniae strain R46 isolated from a rabbit. …”
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Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures by Kyung Min Kang, Jeoung Eun Lee, Ji Eun Park, Hyunjin Kim, Hee Yeon Jang, Minyeon Go, Dong Ryul Lee, Sung Han Shim

“…While studies on embryonic stem cells have been actively conducted, little is known about the epigenetic mechanisms in human embryonic stem cells (hESCs) in extended culture systems. …”
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Barriers to and facilitators of healthcare professionals in ADR reporting in a tertiary care hospital in India by Ian Osoro N, Suhaib KP, Jamuna Rani R, Rajanandh MG

“…Results Out of the 80 HCPs, only 22 of them had reported any ADRs in their career. 52% of our HCPs reported the lack of understanding of ADR reporting mechanism as their main hindrance. Additionally, 25 (31%) of the HCPs stated that reporting ADRs is time consuming. 18 (22%) of them reported a fear of legal liability. 13 (16%) of them stated that the reporting from is complicated and 29 (36%) stated a lack of motivation as the reason for not reporting ADR. …”
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Strawberry plant growth enhancement: Effects of artificial light and methyl jasmonate-salicylic acid treatments on physiology and metabolism by M. Adrian, Roedhy Poerwanto, Eiichi Inoue, Deden Derajat Matra

“…The secondary metabolite analysis, conducted using GC-MS and LC-MS, identified key defense-related compounds, including terpenoids, saturated fats, alkaloids, and amino acid derivatives, which play a role in the plant's defense mechanisms. These findings highlight the potential of LED lighting and hormone applications to modulate strawberry physiology and suggest further research into their role in plant stress responses.…”
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miR-129-5p Regulates the Immunomodulatory Functions of Adipose-Derived Stem Cells via Targeting Stat1 Signaling by He-Yang Zhang, Yu-Han Wang, Yan Wang, Yan-Nv Qu, Xiao-Hui Huang, Hui-Xin Yang, Chang-Ming Zhao, Youdi He, Si-Wei Li, Jin Zhou, Changyong Wang, Xiao-Xia Jiang

“…These novel insights into the mechanisms of ASC immunoregulation may lead to the consistent production of ASCs with strong immunosuppressive functions and thus better clinical utility of these cells.…”
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Isolation and characterization of cadmium-resistant Bacillus cereus strains from Cd-contaminated mining areas for potential bioremediation applications by Bixia Liang, Yimeng Feng, Xiyue Ji, Chune Li, Qian Li, Zhenshun Zeng, Yuqi Wang

“…Future research will focus on elucidating the molecular mechanisms underlying heavy-metal resistance and optimizing their application in large-scale bioremediation strategies.…”
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Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy by Kun Wang, Yingying Zhang, Zhaoming Su, Bei Wang, Yuanyang Zhou, Xiaochu Tong, Chengying Xie, Xiaomin Luo, Sulin Zhang, Mingyue Zheng

“…And we curated two ICI treatment cohorts for validation. We explored the mechanism based on The Cancer Genome Atlas database. …”
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Role of estuarine natural flocculation process in removal of Cu, Mn, Ni, Pb and Zn by S. Hassani, A.R. Karbassi, M. Ardestani

“…This study is performed to evaluate the mechanism of self-purification of heavy metals in Sardabroud's estuary. …”
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Characterization of a chemically induced osteoarthritis model in zebrafish by Gongyi Xiao, Jin Qin, Huiping Yang, Qizhi Song, Ruobin Zhang, Junlan Huang, Yuexi Mou, Wen Liu, Xianding Sun, Mao Nie

“…In the future, this model could serve as a valuable platform for delving deeper into the mechanisms of this disease, as well as for advancing drug discovery and therapeutic interventions. …”
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Role of central retinal artery and ophthalmic artery color doppler imaging in patients with increased intraocular pressure by Alka Agrawal, Gaurav Bhandari, Suhas Kattigowda, Mayank Patidar, Manzill JP

“…Background: Glaucoma is a leading cause of irreversible blindness and involves complex multifactorial mechanisms, with vascular dysregulation playing a crucial role.Objectives: This study aimed to evaluate the utility of Color Doppler Imaging (CDI) in detecting early vascular changes in patients with elevated intraocular pressure (IOP) who do not exhibit detectable visual field defects.Methods: This cross-sectional study was conducted at MGM Medical College and MY Hospital, involving 100 patients divided into groups based on the presence or absence of visual field changes. …”
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Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO by Sue J. Hong, Bradley J. De Souza, Kristen K. Penberthy, Lisa Hwang, David E. Procaccini, John N. Kheir, Melania M. Bembea

“…Understanding these mechanisms of injury through biomarker analysis supports potential neuroprotective strategies such as individualized blood pressure targets, judicious hypercarbia and hypoxemia correction, and immunomodulation (inhaled hydrogen and N-acetylcysteine). …”
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Phenotypic Presentation of Children with Joint Hypermobility: Preclinical Signs by Mateus Marino Lamari, Neuseli Marino Lamari, Michael Peres de Medeiros, Gerardo Maria de Araújo Filho, Adriana Barbosa Santos, Matheus Gomes Giacomini, Vitor Roberto Pugliesi Marques, Eny Maria Goloni-Bertollo, Érika Cristina Pavarino

“…Characteristics related to the sitting position with atypical body positions, such as sitting in splits (S), with the foot on the head (F), in W (W), in a concave shape (C), episodes of dislocations, and subluxations, suggest impacts on body mechanics since childhood, with damage to the conformation of the joints. …”
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Intelligent clustering using moth flame optimizer for vehicular ad hoc networks by Atif Ishtiaq, Sheeraz Ahmed, Muhammad Fahad Khan, Farhan Aadil, Muazzam Maqsood, Salabat Khan

“…Furthermore, it provides a robust routing mechanism based on the clustering. It is suitable for large highways for the productivity of quality communication, reliable delivery for each vehicle and can be widely applicant.…”
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A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte by Letizia Mezzasoma, Cinzia Antognelli, Vincenzo Nicola Talesa

“…Here, we newly demonstrated that, in human THP-1 monocytes, LPS/ATP-induced IL-1β secretion is strongly inhibited by BNP/NPR-1/cGMP axis at all the molecular mechanisms that tightly control its production and release, NF-kB, ERK 1/2, and all the elements of NALP3/ASC/Caspase-1 inflammasome cascade, and that NALP3 inflammasome inhibition is directly related to BNP deregulatory effect on NF-kB/ERK 1/2 activation. …”
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Using Attention for Improving Defect Detection in Existing RC Bridges by Sergio Ruggieri, Angelo Cardellicchio, Andrea Nettis, Vito Reno, Giuseppina Uva

“…Consequently, an improved version of YOLO11, embedding attention mechanisms to allow the network to focus on the most relevant details in each image, was trained, tested, and validated on the provided dataset, showing an overall improvement of quantitative metrics such as precision and recall, while retaining enough computational efficiency to allow real-time implementation on constrained devices. …”
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Geometric model for dynamics of motor-driven centrosomal asters by Yuan-Nan Young, Vicente Gomez Herrera, Huan Zhang, Reza Farhadifar, Michael J. Shelley

“…Our findings both explain experimental observations, providing insights into the mechanisms governing spindle positioning and cell division dynamics, and show the possibility of new nonlinear phenomena in cell biology.…”
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